-
1
-
-
84873472629
-
Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies
-
Eriksson S, Graf EH, Dahl V, et al. Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies. PLoS Pathog 2013;9:e1003174.
-
(2013)
PLoS Pathog
, vol.9
, pp. e1003174
-
-
Eriksson, S.1
Graf, E.H.2
Dahl, V.3
-
2
-
-
84946096080
-
Precise quantita-tion of the latent HIV-1 reservoir: Implications for eradication strategies
-
Crooks AM, Bateson R, Cope AB, et al. Precise quantita-tion of the latent HIV-1 reservoir: Implications for eradication strategies. J Infect Dis 2015;212:1361-1365.
-
(2015)
J Infect Dis
, vol.212
, pp. 1361-1365
-
-
Crooks, A.M.1
Bateson, R.2
Cope, A.B.3
-
3
-
-
84886769508
-
Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure
-
Ho YC, Shan L, Hosmane NN, et al. Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure. Cell 2013;155:540-551.
-
(2013)
Cell
, vol.155
, pp. 540-551
-
-
Ho, Y.C.1
Shan, L.2
Hosmane, N.N.3
-
4
-
-
84907240033
-
Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1
-
Hill AL, Rosenbloom DI, Fu F, Nowak MA, Siliciano RF. Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1. Proc Natl Acad Sci U S A 2014;111: 13475-13480.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 13475-13480
-
-
Hill, A.L.1
Rosenbloom, D.I.2
Fu, F.3
Nowak, M.A.4
Siliciano, R.F.5
-
6
-
-
84877278315
-
Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation
-
Henrich TJ, Hu ZX, Li JZ, et al. Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation. J Infect Dis 2013;207:1694-1702.
-
(2013)
J Infect Dis
, vol.207
, pp. 1694-1702
-
-
Henrich, T.J.1
Hu, Z.X.2
Li, J.Z.3
-
7
-
-
60549090253
-
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
-
Hutter G, Nowak D, Mossner M, et al. Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N Engl J Med 2009;360:692-698.
-
(2009)
N Engl J Med
, vol.360
, pp. 692-698
-
-
Hutter, G.1
Nowak, D.2
Mossner, M.3
-
8
-
-
84942930968
-
T cell engineering as therapy for cancer and HIV: Our synthetic future
-
June CH, Levine BL. T cell engineering as therapy for cancer and HIV: Our synthetic future. Philos Trans R Soc Lond B Biol Sci 2015;370:20140374.
-
(2015)
Philos Trans R Soc Lond B Biol Sci
, vol.370
, pp. 20140374
-
-
June, C.H.1
Levine, B.L.2
-
10
-
-
85002582201
-
In vivo disruption of latent HSV by designer endonuclease therapy
-
Aubert M, Madden EA, Loprieno M, et al. In vivo disruption of latent HSV by designer endonuclease therapy. JCI Insight 2016;1:e88468.
-
(2016)
JCI Insight
, vol.1
, pp. e88468
-
-
Aubert, M.1
Madden, E.A.2
Loprieno, M.3
-
11
-
-
84969706258
-
Excision of HIV-1 DNA by gene editing: A proof-of-concept in vivo study
-
Kaminski R, Bella R, Yin C, et al. Excision of HIV-1 DNA by gene editing: A proof-of-concept in vivo study. Gene Ther 2016;23:690-695.
-
(2016)
Gene Ther
, vol.23
, pp. 690-695
-
-
Kaminski, R.1
Bella, R.2
Yin, C.3
-
12
-
-
84940105412
-
Exclusive transduction of human CD4+ T cells upon systemic delivery of CD4-targeted lentiviral vectors
-
Zhou Q, Uhlig KM, Muth A, et al. Exclusive transduction of human CD4+ T cells upon systemic delivery of CD4-targeted lentiviral vectors. J Immunol 2015;195:2493-2501.
-
(2015)
J Immunol
, vol.195
, pp. 2493-2501
-
-
Zhou, Q.1
Uhlig, K.M.2
Muth, A.3
-
13
-
-
79951783813
-
Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI
-
Aubert M, Ryu BY, Banks L, Rawlings DJ, Scharenberg AM, Jerome KR. Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI. PLoS One 2011;6:e16825.
-
(2011)
PLoS One
, vol.6
, pp. e16825
-
-
Aubert, M.1
Ryu, B.Y.2
Banks, L.3
Rawlings, D.J.4
Scharenberg, A.M.5
Jerome, K.R.6
-
14
-
-
84957595555
-
Digital detection of endonuclease mediated gene disruption in the HIV provirus
-
Sedlak RH, Liang S, Niyonzima N, et al. Digital detection of endonuclease mediated gene disruption in the HIV provirus. Sci Rep 2016;6:20064.
-
(2016)
Sci Rep
, vol.6
, pp. 20064
-
-
Sedlak, R.H.1
Liang, S.2
Niyonzima, N.3
-
15
-
-
84928739868
-
The CRISPR/Cas9 system inactivates latent HIV-1 proviral DNA
-
Zhu W, Lei R, Le Duff Y, et al. The CRISPR/Cas9 system inactivates latent HIV-1 proviral DNA. Retrovirology 2015; 12:22.
-
(2015)
Retrovirology
, vol.12
, pp. 22
-
-
Zhu, W.1
Lei, R.2
Le Duff, Y.3
-
16
-
-
84893869053
-
In vitro inactivation of latent HSV by targeted mutagenesis using an HSV-specific homing endonuclease
-
Aubert M, Boyle NM, Stone D, et al. In vitro inactivation of latent HSV by targeted mutagenesis using an HSV-specific homing endonuclease. Mol Ther Nucleic Acids 2014;3:e146.
-
(2014)
Mol Ther Nucleic Acids
, vol.3
, pp. e146
-
-
Aubert, M.1
Boyle, N.M.2
Stone, D.3
-
17
-
-
84867061435
-
Coupling endo-nucleases with DNA end-processing enzymes to drive gene disruption
-
Certo MT, Gwiazda KS, Kuhar R, et al. Coupling endo-nucleases with DNA end-processing enzymes to drive gene disruption. Nat Methods 2012;9:973-975.
-
(2012)
Nat Methods
, vol.9
, pp. 973-975
-
-
Certo, M.T.1
Gwiazda, K.S.2
Kuhar, R.3
-
18
-
-
84885008722
-
Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells
-
Qu X, Wang P, Ding D, et al. Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells. Nucleic Acids Res 2013;41:7771-7782.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 7771-7782
-
-
Qu, X.1
Wang, P.2
Ding, D.3
-
19
-
-
84924943941
-
A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector
-
Ebina H, Kanemura Y, Misawa N, et al. A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector. PLoS One 2015;10:e0120047.
-
(2015)
PLoS One
, vol.10
, pp. e0120047
-
-
Ebina, H.1
Kanemura, Y.2
Misawa, N.3
-
20
-
-
84905643812
-
RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
-
Hu W, Kaminski R, Yang F, et al. RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection. Proc Natl Acad Sci U S A 2014;111:11461-11466.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 11461-11466
-
-
Hu, W.1
Kaminski, R.2
Yang, F.3
-
21
-
-
84924365668
-
Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells
-
Liao HK, Gu Y, Diaz A, et al. Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells. Nat Commun 2015;6:6413.
-
(2015)
Nat Commun
, vol.6
, pp. 6413
-
-
Liao, H.K.1
Gu, Y.2
Diaz, A.3
-
22
-
-
84952863766
-
HIV excision utilizing CRISPR/Cas9 technology: Attacking the proviral quasispecies in reservoirs to achieve a cure
-
Dampier W, Nonnemacher MR, Sullivan NT, Jacobson JM, Wigdahl B. HIV excision utilizing CRISPR/Cas9 technology: Attacking the proviral quasispecies in reservoirs to achieve a cure. MOJ Immunol 2014;1:pii:00022.
-
(2014)
MOJ Immunol
, vol.1
-
-
Dampier, W.1
Nonnemacher, M.R.2
Sullivan, N.T.3
Jacobson, J.M.4
Wigdahl, B.5
-
23
-
-
84866176440
-
Targeted DNA mutagenesis for the cure of chronic viral infections
-
Schiffer JT, Aubert M, Weber ND, Mintzer E, Stone D, Jerome KR. Targeted DNA mutagenesis for the cure of chronic viral infections. J Virol 2012;86:8920-8936.
-
(2012)
J Virol
, vol.86
, pp. 8920-8936
-
-
Schiffer, J.T.1
Aubert, M.2
Weber, N.D.3
Mintzer, E.4
Stone, D.5
Jerome, K.R.6
-
24
-
-
84880799657
-
Predictors of hepatitis B cure using gene therapy to deliver DNA cleavage enzymes: A mathematical modeling approach
-
Schiffer JT, Swan DA, Stone D, Jerome KR. Predictors of hepatitis B cure using gene therapy to deliver DNA cleavage enzymes: A mathematical modeling approach. PLoS Comput Biol 2013;9:e1003131.
-
(2013)
PLoS Comput Biol
, vol.9
, pp. e1003131
-
-
Schiffer, J.T.1
Swan, D.A.2
Stone, D.3
Jerome, K.R.4
-
25
-
-
84953225653
-
Emergence of treatment-resistant infectious HIV after genome-directed antiviral endonuclease therapy
-
De Silva Feelixge HS, Stone D, Pietz HL, et al. Emergence of treatment-resistant infectious HIV after genome-directed antiviral endonuclease therapy. Antiviral Res 2016;126:90-98.
-
(2016)
Antiviral Res
, vol.126
, pp. 90-98
-
-
De Silva Feelixge, H.S.1
Stone, D.2
Pietz, H.L.3
-
26
-
-
84960380460
-
CRISPR-Cas9 can inhibit HIV-1 replication but NHEJ repair facilitates virus escape
-
Wang G, Zhao N, Berkhout B, Das AT. CRISPR-Cas9 can inhibit HIV-1 replication but NHEJ repair facilitates virus escape. Mol Ther 2016;24:522-526.
-
(2016)
Mol Ther
, vol.24
, pp. 522-526
-
-
Wang, G.1
Zhao, N.2
Berkhout, B.3
Das, A.T.4
-
27
-
-
84978370136
-
Host double strand break repair generates HIV-1 strains resistant to CRISPR/Cas9
-
Yoder KE, Bundschuh R. Host double strand break repair generates HIV-1 strains resistant to CRISPR/Cas9. Sci Rep 2016;6:29530.
-
(2016)
Sci Rep
, vol.6
, pp. 29530
-
-
Yoder, K.E.1
Bundschuh, R.2
-
28
-
-
84962726170
-
CRISPR/Cas9-derived mutations both inhibit HIV-1 replication and accelerate viral escape
-
Wang Z, Pan Q, Gendron P, et al. CRISPR/Cas9-derived mutations both inhibit HIV-1 replication and accelerate viral escape. Cell Rep 2016;15:481-489.
-
(2016)
Cell Rep
, vol.15
, pp. 481-489
-
-
Wang, Z.1
Pan, Q.2
Gendron, P.3
-
30
-
-
84976293053
-
Genome editing and the next generation of antiviral therapy
-
Stone D, Niyonzima N, Jerome KR. Genome editing and the next generation of antiviral therapy. Hum Genet 2016; 135:1071-1082.
-
(2016)
Hum Genet
, vol.135
, pp. 1071-1082
-
-
Stone, D.1
Niyonzima, N.2
Jerome, K.R.3
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