Evidence that factor VIII forms a bivalent complex with the Low Density Lipoprotein (LDL) Receptor-related Protein 1 (LRP1): Identification of cluster IV on LRP1 as the major binding site

Journal of Biological Chemistry

Volumn 291, Issue 50, 2016, Pages 26035-26044

  Young, Patricia A ^a   Migliorini, Mary ^a   Strickland, Dudley K ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING SITES; CHEMICAL MODIFICATION; IONIC STRENGTH; PROTEINS; SURFACE PLASMON RESONANCE;

BLEEDING DISORDER; CHARGED RESIDUES; COAGULATION FACTOR; HIGH AFFINITY; IONIC STRENGTH DEPENDENCE; KINETIC STUDY; LOW DENSITY LIPOPROTEIN RECEPTORS; LYSINE RESIDUES;

BINS;

BLOOD CLOTTING FACTOR 8; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LYSINE; F8 PROTEIN, HUMAN; LRP1 PROTEIN, HUMAN; MULTIPROTEIN COMPLEX;

ANIMAL CELL; ARTICLE; BINDING SITE; CHEMICAL MODIFICATION; CONTROLLED STUDY; IONIC STRENGTH; KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY; SURFACE PLASMON RESONANCE; ANIMAL; CELL LINE; CHEMISTRY; GENETICS; HAMSTER; HUMAN; MALE; METABOLISM;

ANIMALS; BINDING SITES; CELL LINE; CRICETINAE; FACTOR VIII; HUMANS; KINETICS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-1; MALE; MULTIPROTEIN COMPLEXES; SURFACE PLASMON RESONANCE;

EID: 85002728254     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.754622     Document Type: Article

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