Shear stress-independent binding of von Willebrand factor-type 2B mutants p.R1306Q & p.V1316M to LRP1 explains their increased clearance

Journal of Thrombosis and Haemostasis

Volumn 13, Issue 5, 2015, Pages 815-820

  Wohner, N ^a   Legendre, P ^a   Casari, C ^a   Christophe, O D ^a   Lenting, P J ^a   Denis, C V ^a  

^a Dept Environ Med Natl Inst Publ HIth   (Norway)

Author keywords

Half life; LDL receptor related proteins; Protein protein interaction domains; Von Willebrand disease; Von Willebrand factor

Indexed keywords

LIPOPROTEIN RECEPTOR; VON WILLEBRAND FACTOR; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LRP1 PROTEIN, HUMAN; PROTEIN BINDING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CONTROLLED STUDY; FEMALE; MACROPHAGE; MALE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; SHEAR STRESS; VON WILLEBRAND DISEASE; ANIMAL; GENETICS; MECHANICAL STRESS; METABOLISM; MOUSE; SHEAR STRENGTH;

ANIMALS; FEMALE; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-1; MALE; MICE; MUTATION; PROTEIN BINDING; SHEAR STRENGTH; STRESS, MECHANICAL; VON WILLEBRAND FACTOR;

EID: 84928753943     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.12885     Document Type: Article

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