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Volumn 197, Issue 12, 2016, Pages 4639-4650

The nuclear receptor AhR controls bone homeostasis by regulating osteoclast differentiation via the RANK/c-fos signaling axis

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; CATHEPSIN K; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NFAT CYTOPLASMIC CALCINEURIN DEPENDENT 1; PROTEIN C FOS; PROTEIN KINASE B; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; BENZO[A]PYRENE DERIVATIVE; OSTEOCLAST DIFFERENTIATION FACTOR; TNFSF11 PROTEIN, MOUSE;

EID: 85002180250     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1600822     Document Type: Article
Times cited : (55)

References (55)
  • 1
    • 27544434863 scopus 로고    scopus 로고
    • Molecular mechanisms of AhR functions in the regulation of cytochrome P450 genes
    • Fujii-Kuriyama, Y., and J. Mimura. 2005. Molecular mechanisms of AhR functions in the regulation of cytochrome P450 genes. Biochem. Biophys. Res. Commun. 338: 311-317.
    • (2005) Biochem. Biophys. Res. Commun , vol.338 , pp. 311-317
    • Fujii-Kuriyama, Y.1    Mimura, J.2
  • 2
    • 0037450429 scopus 로고    scopus 로고
    • Functional role of AhR in the expression of toxic effects by TCDD
    • Mimura, J., and Y. Fujii-Kuriyama. 2003. Functional role of AhR in the expression of toxic effects by TCDD. Biochim. Biophys. Acta 1619: 263-268.
    • (2003) Biochim. Biophys. Acta , vol.1619 , pp. 263-268
    • Mimura, J.1    Fujii-Kuriyama, Y.2
  • 3
    • 0036721571 scopus 로고    scopus 로고
    • 3-Methylcholanthrene, which binds to the arylhydrocarbon receptor, inhibits proliferation and differentiation of osteoblasts in vitro and ossification in vivo
    • Naruse, M., Y. Ishihara, S. Miyagawa-Tomita, A. Koyama, and H. Hagiwara. 2002. 3-Methylcholanthrene, which binds to the arylhydrocarbon receptor, inhibits proliferation and differentiation of osteoblasts in vitro and ossification in vivo. Endocrinology 143: 3575-3581.
    • (2002) Endocrinology , vol.143 , pp. 3575-3581
    • Naruse, M.1    Ishihara, Y.2    Miyagawa-Tomita, S.3    Koyama, A.4    Hagiwara, H.5
  • 4
    • 0037145025 scopus 로고    scopus 로고
    • The role of chaperone proteins in the aryl hydrocarbon receptor core complex
    • Petrulis, J. R., and G. H. Perdew. 2002. The role of chaperone proteins in the aryl hydrocarbon receptor core complex. Chem. Biol. Interact. 141: 25-40.
    • (2002) Chem. Biol. Interact , vol.141 , pp. 25-40
    • Petrulis, J.R.1    Perdew, G.H.2
  • 6
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • Teitelbaum, S. L. 2000. Bone resorption by osteoclasts. Science 289: 1504-1508.
    • (2000) Science , vol.289 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 7
    • 30644469500 scopus 로고    scopus 로고
    • RANKL-RANK signaling in osteoclastogenesis and bone disease
    • Wada, T., T. Nakashima, N. Hiroshi, and J. M. Penninger. 2006. RANKL-RANK signaling in osteoclastogenesis and bone disease. Trends Mol. Med. 12: 17-25.
    • (2006) Trends Mol. Med , vol.12 , pp. 17-25
    • Wada, T.1    Nakashima, T.2    Hiroshi, N.3    Penninger, J.M.4
  • 8
    • 33947583822 scopus 로고    scopus 로고
    • Osteoimmunology: Shared mechanisms and crosstalk between the immune and bone systems
    • Takayanagi, H. 2007. Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat. Rev. Immunol. 7: 292-304.
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 292-304
    • Takayanagi, H.1
  • 10
    • 0033621698 scopus 로고    scopus 로고
    • Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation
    • Matsuo, K., J. M. Owens, M. Tonko, C. Elliott, T. J. Chambers, and E. F.Wagner. 2000. Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation. Nat. Genet. 24: 184-187.
    • (2000) Nat. Genet , vol.24 , pp. 184-187
    • Matsuo, K.1    Owens, J.M.2    Tonko, M.3    Elliott, C.4    Chambers, T.J.5    Wagner, F.E.6
  • 12
    • 84904766846 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor catabolic activity in bone metabolism is osteoclast dependent in vivo
    • Yu, T. Y., T. Kondo, T. Matsumoto, Y. Fujii-Kuriyama, and Y. Imai. 2014. Aryl hydrocarbon receptor catabolic activity in bone metabolism is osteoclast dependent in vivo. Biochem. Biophys. Res. Commun. 450: 416-422.
    • (2014) Biochem. Biophys. Res. Commun , vol.450 , pp. 416-422
    • Yu, T.Y.1    Kondo, T.2    Matsumoto, T.3    Fujii-Kuriyama, Y.4    Imai, Y.5
  • 13
    • 84921805765 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptors in osteoclast lineage cells are a negative regulator of bone mass
    • Yu, T. Y., W. J. Pang, and G. S. Yang. 2015. Aryl hydrocarbon receptors in osteoclast lineage cells are a negative regulator of bone mass. PLoS One 10: e0117112.
    • (2015) PLoS One , vol.10
    • Yu, T.Y.1    Pang, W.J.2    Yang, G.S.3
  • 14
    • 77951582963 scopus 로고    scopus 로고
    • Transgenic mice with a constitutively active aryl hydrocarbon receptor display a gender-specific bone phenotype
    • Wejheden, C., S. Brunnberg, S. Larsson, P. M. Lind, G. Andersson, and A. Hanberg. 2010. Transgenic mice with a constitutively active aryl hydrocarbon receptor display a gender-specific bone phenotype. Toxicol. Sci. 114: 48-58.
    • (2010) Toxicol. Sci , vol.114 , pp. 48-58
    • Wejheden, C.1    Brunnberg, S.2    Larsson, S.3    Lind, P.M.4    Andersson, G.5    Hanberg, A.6
  • 16
    • 9944255780 scopus 로고    scopus 로고
    • Role of coactivators in transcriptional activation by the aryl hydrocarbon receptor
    • Hankinson, O. 2005. Role of coactivators in transcriptional activation by the aryl hydrocarbon receptor. Arch. Biochem. Biophys. 433: 379-386.
    • (2005) Arch. Biochem. Biophys , vol.433 , pp. 379-386
    • Hankinson, O.1
  • 17
    • 0042303885 scopus 로고    scopus 로고
    • Rapid communication: Effects of tobacco processing on the quantity of benzo[a]pyrene in mainstream smoke
    • Martin, L. A., S. K. Byrd, and R. E. Milofsky. 2003. Rapid communication: effects of tobacco processing on the quantity of benzo[a]pyrene in mainstream smoke. J. Toxicol. Environ. Health A 66: 1283-1286.
    • (2003) J. Toxicol. Environ. Health A , vol.66 , pp. 1283-1286
    • Martin, L.A.1    Byrd, S.K.2    Milofsky, R.E.3
  • 18
    • 0035992120 scopus 로고    scopus 로고
    • Biomonitoring of tobacco smoke carcinogenicity by dosimetry of DNA adducts and genotyping and phenotyping of biotransformational enzymes: A review on polycyclic aromatic hydrocarbons
    • Besaratinia, A., J. C. Kleinjans, and F. J. Van Schooten. 2002. Biomonitoring of tobacco smoke carcinogenicity by dosimetry of DNA adducts and genotyping and phenotyping of biotransformational enzymes: a review on polycyclic aromatic hydrocarbons. Biomarkers 7: 209-229.
    • (2002) Biomarkers , vol.7 , pp. 209-229
    • Besaratinia, A.1    Kleinjans, J.C.2    Van Schooten, F.J.3
  • 22
  • 24
  • 25
    • 0033940801 scopus 로고    scopus 로고
    • Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts
    • Takeshita, S., K. Kaji, and A. Kudo. 2000. Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts. J. Bone Miner. Res. 15: 1477-1488.
    • (2000) J. Bone Miner. Res , vol.15 , pp. 1477-1488
    • Takeshita, S.1    Kaji, K.2    Kudo, A.3
  • 27
    • 0142227052 scopus 로고    scopus 로고
    • Retrovirus-mediated gene transfer and expression cloning: Powerful tools in functional genomics
    • Kitamura, T., Y. Koshino, F. Shibata, T. Oki, H. Nakajima, T. Nosaka, and H. Kumagai. 2003. Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics. Exp. Hematol. 31: 1007-1014.
    • (2003) Exp. Hematol , vol.31 , pp. 1007-1014
    • Kitamura, T.1    Koshino, Y.2    Shibata, F.3    Oki, T.4    Nakajima, H.5    Nosaka, T.6    Kumagai, H.7
  • 28
    • 33947497852 scopus 로고    scopus 로고
    • Osteoclasts: What do they do and how do they do it?
    • Teitelbaum, S. L. 2007. Osteoclasts: what do they do and how do they do it? Am. J. Pathol. 170: 427-435.
    • (2007) Am. J. Pathol , vol.170 , pp. 427-435
    • Teitelbaum, S.L.1
  • 29
    • 17044368385 scopus 로고    scopus 로고
    • Regulatory roles and molecular signaling of TNF family members in osteoclasts
    • Feng, X. 2005. Regulatory roles and molecular signaling of TNF family members in osteoclasts. Gene 350: 1-13.
    • (2005) Gene , vol.350 , pp. 1-13
    • Feng, X.1
  • 31
    • 33846031926 scopus 로고    scopus 로고
    • The molecular understanding of osteoclast differentiation
    • Asagiri, M., and H. Takayanagi. 2007. The molecular understanding of osteoclast differentiation. Bone 40: 251-264.
    • (2007) Bone , vol.40 , pp. 251-264
    • Asagiri, M.1    Takayanagi, H.2
  • 35
    • 77956408841 scopus 로고    scopus 로고
    • PGC1b mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss
    • Wei, W., X. Wang, M. Yang, L. C. Smith, P. C. Dechow, J. Sonoda, R. M. Evans, and Y. Wan. 2010. PGC1b mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss. Cell Metab. 11: 503-516.
    • (2010) Cell Metab , vol.11 , pp. 503-516
    • Wei, W.1    Wang, X.2    Yang, M.3    Smith, L.C.4    Dechow, P.C.5    Sonoda, J.6    Evans, R.M.7    Wan, Y.8
  • 36
    • 36849034568 scopus 로고    scopus 로고
    • PPAR-g regulates osteoclastogenesis in mice
    • Wan, Y., L. W. Chong, and R. M. Evans. 2007. PPAR-g regulates osteoclastogenesis in mice. Nat. Med. 13: 1496-1503.
    • (2007) Nat. Med , vol.13 , pp. 1496-1503
    • Wan, Y.1    Chong, L.W.2    Evans, R.M.3
  • 37
    • 84954076692 scopus 로고    scopus 로고
    • Alternative NF-kB regulates RANKL-induced osteoclast differentiation and mitochondrial biogenesis via independent mechanisms
    • Zeng, R., R. Faccio, and D. V. Novack. 2015. Alternative NF-kB regulates RANKL-induced osteoclast differentiation and mitochondrial biogenesis via independent mechanisms. J. Bone Miner. Res. 30: 2287-2299.
    • (2015) J. Bone Miner. Res , vol.30 , pp. 2287-2299
    • Zeng, R.1    Faccio, R.2    Novack, D.V.3
  • 38
    • 0035075677 scopus 로고    scopus 로고
    • Molecular aspects of healing in stabilized and non-stabilized fractures
    • Le, A. X., T. Miclau, D. Hu, and J. A. Helms. 2001. Molecular aspects of healing in stabilized and non-stabilized fractures. J. Orthop. Res. 19: 78-84.
    • (2001) J. Orthop. Res , vol.19 , pp. 78-84
    • Le, A.X.1    Miclau, T.2    Hu, D.3    Helms, J.A.4
  • 39
    • 84904887392 scopus 로고    scopus 로고
    • Mechanisms of osteoclast-dependent bone formation
    • Teti, A. 2013. Mechanisms of osteoclast-dependent bone formation. Bonekey Rep. 2:449.
    • (2013) Bonekey Rep , vol.2 , pp. 449
    • Teti, A.1
  • 44
    • 18744366041 scopus 로고    scopus 로고
    • Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
    • Takayanagi, H., S. Kim, T. Koga, H. Nishina, M. Isshiki, H. Yoshida, A. Saiura, M. Isobe, T. Yokochi, J. Inoue, et al. 2002. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev. Cell 3: 889-901.
    • (2002) Dev. Cell , vol.3 , pp. 889-901
    • Takayanagi, H.1    Kim, S.2    Koga, T.3    Nishina, H.4    Isshiki, M.5    Yoshida, H.6    Saiura, A.7    Isobe, M.8    Yokochi, T.9    Inoue, J.10
  • 45
    • 84155192347 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated impairment of chondrogenesis and fracture healing by cigarette smoke and benzo(a)pyrene
    • Kung, M. H., K. Yukata, R. J. O'Keefe, and M. J. Zuscik. 2012. Aryl hydrocarbon receptor-mediated impairment of chondrogenesis and fracture healing by cigarette smoke and benzo(a)pyrene. J. Cell. Physiol. 227: 1062-1070.
    • (2012) J. Cell. Physiol , vol.227 , pp. 1062-1070
    • Kung, M.H.1    Yukata, K.2    O'Keefe, R.J.3    Zuscik, M.J.4
  • 46
    • 77951213242 scopus 로고    scopus 로고
    • RANKL-mediated reactive oxygen species pathway that induces long lasting Ca2+ oscillations essential for osteoclastogenesis
    • Kim, M. S., Y. M. Yang, A. Son, Y. S. Tian, S. I. Lee, S. W. Kang, S. Muallem, and D. M. Shin. 2010. RANKL-mediated reactive oxygen species pathway that induces long lasting Ca2+ oscillations essential for osteoclastogenesis. J. Biol. Chem. 285: 6913-6921.
    • (2010) J. Biol. Chem , vol.285 , pp. 6913-6921
    • Kim, M.S.1    Yang, Y.M.2    Son, A.3    Tian, Y.S.4    Lee, S.I.5    Kang, S.W.6    Muallem, S.7    Shin, D.M.8
  • 49
    • 34247590356 scopus 로고    scopus 로고
    • PGC-1b controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis
    • Sonoda, J., I. R. Mehl, L. W. Chong, R. R. Nofsinger, and R. M. Evans. 2007. PGC-1b controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis. Proc. Natl. Acad. Sci. USA 104: 5223-5228.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 5223-5228
    • Sonoda, J.1    Mehl, I.R.2    Chong, L.W.3    Nofsinger, R.R.4    Evans, R.M.5
  • 50
    • 33845674997 scopus 로고    scopus 로고
    • The transcriptional coactivator PGC-1b drives the formation of oxidative type IIX fibers in skeletal muscle
    • Arany, Z., N. Lebrasseur, C. Morris, E. Smith, W. Yang, Y. Ma, S. Chin, and B. M. Spiegelman. 2007. The transcriptional coactivator PGC-1b drives the formation of oxidative type IIX fibers in skeletal muscle. Cell Metab. 5: 35-46.
    • (2007) Cell Metab , vol.5 , pp. 35-46
    • Arany, Z.1    Lebrasseur, N.2    Morris, C.3    Smith, E.4    Yang, W.5    Ma, Y.6    Chin, S.7    Spiegelman, B.M.8
  • 55
    • 0036259278 scopus 로고    scopus 로고
    • Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair
    • Zhang, X., E. M. Schwarz, D. A. Young, J. E. Puzas, R. N. Rosier, and R. J. O'Keefe. 2002. Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. J. Clin. Invest. 109: 1405-1415.
    • (2002) J. Clin. Invest , vol.109 , pp. 1405-1415
    • Zhang, X.1    Schwarz, E.M.2    Young, D.A.3    Puzas, J.E.4    Rosier, R.N.5    O'Keefe, R.J.6


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