-
1
-
-
70349269503
-
Leptospira: the dawn of the molecular genetics era for an emerging zoonotic pathogen
-
19756012,.; (): –. PubMed Central PMCID: PMC3384523
-
Ko AI, Goarant C, Picardeau M, Leptospira: the dawn of the molecular genetics era for an emerging zoonotic pathogen. Nature reviews Microbiology. 2009;7(10):736–47. PubMed Central PMCID: PMC3384523. doi: 10.1038/nrmicro220819756012
-
(2009)
Nature reviews Microbiology
, vol.7
, Issue.10
, pp. 736-747
-
-
Ko, A.I.1
Goarant, C.2
Picardeau, M.3
-
2
-
-
34548422845
-
Control of neglected tropical diseases
-
17804846,..; (): –. Epub 2007/09/07
-
Hotez PJ, Molyneux DH, Fenwick A, Kumaresan J, Sachs SE, Sachs JD, et al. Control of neglected tropical diseases. N Engl J Med. 2007;357(10):1018–27. Epub 2007/09/07. doi: 10.1056/NEJMra06414217804846
-
(2007)
N Engl J Med
, vol.357
, Issue.10
, pp. 1018-1027
-
-
Hotez, P.J.1
Molyneux, D.H.2
Fenwick, A.3
Kumaresan, J.4
Sachs, S.E.5
Sachs, J.D.6
-
3
-
-
84943161123
-
Global Morbidity and Mortality of Leptospirosis: A Systematic Review
-
26379143,..; ():. PubMed Central PMCID: PMC4574773
-
Costa F, Hagan JE, Calcagno J, Kane M, Torgerson P, Martinez-Silveira MS, et al. Global Morbidity and Mortality of Leptospirosis: A Systematic Review. PLoS neglected tropical diseases. 2015;9(9):e0003898. PubMed Central PMCID: PMC4574773. doi: 10.1371/journal.pntd.000389826379143
-
(2015)
PLoS neglected tropical diseases
, vol.9
, Issue.9
, pp. e0003898
-
-
Costa, F.1
Hagan, J.E.2
Calcagno, J.3
Kane, M.4
Torgerson, P.5
Martinez-Silveira, M.S.6
-
4
-
-
84956488642
-
Global Burden of Leptospirosis: Estimated in Terms of Disability Adjusted Life Years
-
26431366,..; ():. PubMed Central PMCID: PMC4591975
-
Torgerson PR, Hagan JE, Costa F, Calcagno J, Kane M, Martinez-Silveira MS, et al. Global Burden of Leptospirosis: Estimated in Terms of Disability Adjusted Life Years. PLoS neglected tropical diseases. 2015;9(10):e0004122. PubMed Central PMCID: PMC4591975. doi: 10.1371/journal.pntd.000412226431366
-
(2015)
PLoS neglected tropical diseases
, vol.9
, Issue.10
, pp. e0004122
-
-
Torgerson, P.R.1
Hagan, J.E.2
Costa, F.3
Calcagno, J.4
Kane, M.5
Martinez-Silveira, M.S.6
-
5
-
-
85002253864
-
-
Leptospirosis case notification records, Brazil. Health Surveillance Secretary Brazilian Ministry of Health; 2007.
-
(2007)
-
-
-
6
-
-
84901779232
-
Prospective study of leptospirosis transmission in an urban slum community: role of poor environment in repeated exposures to the Leptospira agent
-
24875389,..; ():. PubMed Central PMCID: PMC4038618
-
Felzemburgh RD, Ribeiro GS, Costa F, Reis RB, Hagan JE, Melendez AX, et al. Prospective study of leptospirosis transmission in an urban slum community: role of poor environment in repeated exposures to the Leptospira agent. PLoS neglected tropical diseases. 2014;8(5):e2927. PubMed Central PMCID: PMC4038618. doi: 10.1371/journal.pntd.000292724875389
-
(2014)
PLoS neglected tropical diseases
, vol.8
, Issue.5
, pp. e2927
-
-
Felzemburgh, R.D.1
Ribeiro, G.S.2
Costa, F.3
Reis, R.B.4
Hagan, J.E.5
Melendez, A.X.6
-
7
-
-
41349093977
-
Leptospirosis-associated severe pulmonary hemorrhagic syndrome, Salvador, Brazil
-
18325275,..; (): –. Epub 2008/03/08. PubMed Central PMCID: PMC2570821
-
Gouveia EL, Metcalfe J, de Carvalho AL, Aires TS, Villasboas-Bisneto JC, Queirroz A, et al. Leptospirosis-associated severe pulmonary hemorrhagic syndrome, Salvador, Brazil. Emerg Infect Dis. 2008;14(3):505–8. Epub 2008/03/08. PubMed Central PMCID: PMC2570821. doi: 10.3201/eid1403.07106418325275
-
(2008)
Emerg Infect Dis
, vol.14
, Issue.3
, pp. 505-508
-
-
Gouveia, E.L.1
Metcalfe, J.2
de Carvalho, A.L.3
Aires, T.S.4
Villasboas-Bisneto, J.C.5
Queirroz, A.6
-
8
-
-
0033396245
-
Acute lung injury in leptospirosis: clinical and laboratory features, outcome, and factors associated with mortality
-
10585813,..; (): –. Epub 1999/12/10
-
Marotto PC, Nascimento CM, Eluf-Neto J, Marotto MS, Andrade L, Sztajnbok J, et al. Acute lung injury in leptospirosis: clinical and laboratory features, outcome, and factors associated with mortality. Clin Infect Dis. 1999;29(6):1561–3. Epub 1999/12/10. doi: 10.1086/31350110585813
-
(1999)
Clin Infect Dis
, vol.29
, Issue.6
, pp. 1561-1563
-
-
Marotto, P.C.1
Nascimento, C.M.2
Eluf-Neto, J.3
Marotto, M.S.4
Andrade, L.5
Sztajnbok, J.6
-
9
-
-
25144436317
-
Leptospirosis
-
16148523,.; (): –
-
McBride AJ, Athanazio DA, Reis MG, Ko AI, Leptospirosis. Current opinion in infectious diseases. 2005;18(5):376–86. 16148523
-
(2005)
Current opinion in infectious diseases
, vol.18
, Issue.5
, pp. 376-386
-
-
McBride, A.J.1
Athanazio, D.A.2
Reis, M.G.3
Ko, A.I.4
-
10
-
-
0036594945
-
Leptospirosis as a cause of acute respiratory failure: clinical features and outcome in 35 critical care patients
-
12144750,.; (): –. Epub 2002/07/30
-
Vieira SR, Brauner JS, Leptospirosis as a cause of acute respiratory failure: clinical features and outcome in 35 critical care patients. Braz J Infect Dis. 2002;6(3):135–9. Epub 2002/07/30. 12144750
-
(2002)
Braz J Infect Dis
, vol.6
, Issue.3
, pp. 135-139
-
-
Vieira, S.R.1
Brauner, J.S.2
-
11
-
-
84869028722
-
Leptospira and inflammation
-
23132959,.;:. PubMed Central PMCID: PMC3485547
-
Goncalves-de-Albuquerque CF, Burth P, Silva AR, Younes-Ibrahim M, Castro-Faria-Neto HC, Castro-Faria MV, Leptospira and inflammation. Mediators of inflammation. 2012;2012:317950. PubMed Central PMCID: PMC3485547. doi: 10.1155/2012/31795023132959
-
(2012)
Mediators of inflammation
, vol.2012
, pp. 317950
-
-
Goncalves-de-Albuquerque, C.F.1
Burth, P.2
Silva, A.R.3
Younes-Ibrahim, M.4
Castro-Faria-Neto, H.C.5
Castro-Faria, M.V.6
-
13
-
-
84861785677
-
Inflammasome-regulated cytokines are critical mediators of acute lung injury
-
22461369,..; (): –. PubMed Central PMCID: PMC3373064
-
Dolinay T, Kim YS, Howrylak J, Hunninghake GM, An CH, Fredenburgh L, et al. Inflammasome-regulated cytokines are critical mediators of acute lung injury. American journal of respiratory and critical care medicine. 2012;185(11):1225–34. PubMed Central PMCID: PMC3373064. doi: 10.1164/rccm.201201-0003OC22461369
-
(2012)
American journal of respiratory and critical care medicine
, vol.185
, Issue.11
, pp. 1225-1234
-
-
Dolinay, T.1
Kim, Y.S.2
Howrylak, J.3
Hunninghake, G.M.4
An, C.H.5
Fredenburgh, L.6
-
14
-
-
84888325490
-
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
-
24232462,.; (): –. PubMed Central PMCID: PMC4077177
-
Hotchkiss RS, Monneret G, Payen D, Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy. Nature reviews Immunology. 2013;13(12):862–74. PubMed Central PMCID: PMC4077177. doi: 10.1038/nri355224232462
-
(2013)
Nature reviews Immunology
, vol.13
, Issue.12
, pp. 862-874
-
-
Hotchkiss, R.S.1
Monneret, G.2
Payen, D.3
-
15
-
-
70350026682
-
Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis
-
19683555,..; (): –
-
Fialho RN, Martins L, Pinheiro JP, Bettencourt BF, Couto AR, Santos MR, et al. Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis. Hum Immunol. 2009;70(11):915–20. doi: 10.1016/j.humimm.2009.08.00719683555
-
(2009)
Hum Immunol
, vol.70
, Issue.11
, pp. 915-920
-
-
Fialho, R.N.1
Martins, L.2
Pinheiro, J.P.3
Bettencourt, B.F.4
Couto, A.R.5
Santos, M.R.6
-
16
-
-
84925432737
-
Association of Toll-like receptor 2 Arg753Gln and Toll-like receptor 1 Ile602Ser single-nucleotide polymorphisms with leptospirosis in an Argentine population
-
25784560,.;: –
-
Cedola M, Chiani Y, Pretre G, Alberdi L, Vanasco B, Gomez RM, Association of Toll-like receptor 2 Arg753Gln and Toll-like receptor 1 Ile602Ser single-nucleotide polymorphisms with leptospirosis in an Argentine population. Acta Trop. 2015;146:73–80. doi: 10.1016/j.actatropica.2015.03.00725784560
-
(2015)
Acta Trop
, vol.146
, pp. 73-80
-
-
Cedola, M.1
Chiani, Y.2
Pretre, G.3
Alberdi, L.4
Vanasco, B.5
Gomez, R.M.6
-
17
-
-
0033523415
-
Urban epidemic of severe leptospirosis in Brazil. Salvador Leptospirosis Study Group
-
10485724,.; (): –. Epub 1999/09/15
-
Ko AI, Galvao Reis M, Ribeiro Dourado CM, Johnson WD, Jr.Riley LW, Urban epidemic of severe leptospirosis in Brazil. Salvador Leptospirosis Study Group. Lancet. 1999;354(9181):820–5. Epub 1999/09/15. 10485724
-
(1999)
Lancet
, vol.354
, Issue.9181
, pp. 820-825
-
-
Ko, A.I.1
Galvao Reis, M.2
Ribeiro Dourado, C.M.3
Johnson, W.D.4
Riley, L.W.5
-
18
-
-
48949118023
-
Impact of environment and social gradient on Leptospira infection in urban slums
-
18431445,..; ():. PubMed Central PMCID: PMC2292260
-
Reis RB, Ribeiro GS, Felzemburgh RD, Santana FS, Mohr S, Melendez AX, et al. Impact of environment and social gradient on Leptospira infection in urban slums. PLoS neglected tropical diseases. 2008;2(4):e228. PubMed Central PMCID: PMC2292260. doi: 10.1371/journal.pntd.000022818431445
-
(2008)
PLoS neglected tropical diseases
, vol.2
, Issue.4
, pp. e228
-
-
Reis, R.B.1
Ribeiro, G.S.2
Felzemburgh, R.D.3
Santana, F.S.4
Mohr, S.5
Melendez, A.X.6
-
19
-
-
0035166437
-
Identification of new repetitive element in Leptospira interrogans serovar copenhageni and its application to PCR-based differentiation of Leptospira serogroups
-
11136769,.; (): –. PubMed Central PMCID: PMC87700
-
Barocchi MA, Ko AI, Ferrer SR, Faria MT, Reis MG, Riley LW, Identification of new repetitive element in Leptospira interrogans serovar copenhageni and its application to PCR-based differentiation of Leptospira serogroups. J Clin Microbiol. 2001;39(1):191–5. PubMed Central PMCID: PMC87700. doi: 10.1128/JCM.39.1.191-195.200111136769
-
(2001)
J Clin Microbiol
, vol.39
, Issue.1
, pp. 191-195
-
-
Barocchi, M.A.1
Ko, A.I.2
Ferrer, S.R.3
Faria, M.T.4
Reis, M.G.5
Riley, L.W.6
-
20
-
-
0036293450
-
Prognostic factors of death in leptospirosis: a prospective cohort study in Khon Kaen, Thailand
-
12044303,.; (): –. Epub 2002/06/05
-
Panaphut T, Domrongkitchaiporn S, Thinkamrop B, Prognostic factors of death in leptospirosis: a prospective cohort study in Khon Kaen, Thailand. Int J Infect Dis. 2002;6(1):52–9. Epub 2002/06/05. 12044303
-
(2002)
Int J Infect Dis
, vol.6
, Issue.1
, pp. 52-59
-
-
Panaphut, T.1
Domrongkitchaiporn, S.2
Thinkamrop, B.3
-
21
-
-
19244362162
-
Association of plasma levels of tumor necrosis factor alpha with severity of disease and mortality among patients with leptospirosis
-
8922824,.; (): –
-
Tajiki H, Salomao R, Association of plasma levels of tumor necrosis factor alpha with severity of disease and mortality among patients with leptospirosis. Clin Infect Dis. 1996;23(5):1177–8. 8922824
-
(1996)
Clin Infect Dis
, vol.23
, Issue.5
, pp. 1177-1178
-
-
Tajiki, H.1
Salomao, R.2
-
22
-
-
79953042117
-
Serum TNF-alpha, sTNFR1, IL-6, IL-8 and IL-10 levels in Weil's syndrome
-
21316985,.; (): –. Epub 2011/02/15
-
Kyriakidis I, Samara P, Papa A, Serum TNF-alpha, sTNFR1, IL-6, IL-8 and IL-10 levels in Weil's syndrome. Cytokine. 2011;54(2):117–20. Epub 2011/02/15. doi: 10.1016/j.cyto.2011.01.01421316985
-
(2011)
Cytokine
, vol.54
, Issue.2
, pp. 117-120
-
-
Kyriakidis, I.1
Samara, P.2
Papa, A.3
-
23
-
-
84884689873
-
Cytokine response signatures in disease progression and development of severe clinical outcomes for leptospirosis
-
24069500,..; ():. PubMed Central PMCID: PMC3777885
-
Reis EA, Hagan JE, Ribeiro GS, Teixeira-Carvalho A, Martins-Filho OA, Montgomery RR, et al. Cytokine response signatures in disease progression and development of severe clinical outcomes for leptospirosis. PLoS neglected tropical diseases. 2013;7(9):e2457. PubMed Central PMCID: PMC3777885. doi: 10.1371/journal.pntd.000245724069500
-
(2013)
PLoS neglected tropical diseases
, vol.7
, Issue.9
, pp. e2457
-
-
Reis, E.A.1
Hagan, J.E.2
Ribeiro, G.S.3
Teixeira-Carvalho, A.4
Martins-Filho, O.A.5
Montgomery, R.R.6
-
24
-
-
85002247129
-
Severity markers in severe leptospirosis: a cohort study
-
Mikulski M, Boisier P, Lacassin F, Soupe-Gilbert ME, Mauron C, Bruyere-Ostells L, et al. Severity markers in severe leptospirosis: a cohort study. European journal of clinical microbiology & infectious diseases: official publication of the European Society of Clinical Microbiology. 2014.
-
(2014)
European journal of clinical microbiology & infectious diseases: official publication of the European Society of Clinical Microbiology
-
-
Mikulski, M.1
Boisier, P.2
Lacassin, F.3
Soupe-Gilbert, M.E.4
Mauron, C.5
Bruyere-Ostells, L.6
-
26
-
-
66749154775
-
Haematological and clinical-chemistry markers in patients presenting with leptospirosis: a comparison of the findings from uncomplicated cases with those seen in the severe disease
-
19508751,.; (): –
-
Craig SB, Graham GC, Burns MA, Dohnt MF, Smythe LD, McKay DB, Haematological and clinical-chemistry markers in patients presenting with leptospirosis: a comparison of the findings from uncomplicated cases with those seen in the severe disease. Annals of tropical medicine and parasitology. 2009;103(4):333–41. doi: 10.1179/136485909X43505819508751
-
(2009)
Annals of tropical medicine and parasitology
, vol.103
, Issue.4
, pp. 333-341
-
-
Craig, S.B.1
Graham, G.C.2
Burns, M.A.3
Dohnt, M.F.4
Smythe, L.D.5
McKay, D.B.6
-
27
-
-
0034536222
-
Neutrophils as early immunologic effectors in hemorrhage- or endotoxemia-induced acute lung injury
-
11076804,.; (): –
-
Abraham E, Carmody A, Shenkar R, Arcaroli J, Neutrophils as early immunologic effectors in hemorrhage- or endotoxemia-induced acute lung injury. American journal of physiology Lung cellular and molecular physiology. 2000;279(6):L1137–45. 11076804
-
(2000)
American journal of physiology Lung cellular and molecular physiology
, vol.279
, Issue.6
, pp. L1137-L1145
-
-
Abraham, E.1
Carmody, A.2
Shenkar, R.3
Arcaroli, J.4
-
28
-
-
84941744544
-
Markers of endothelial cell activation and immune activation are increased in patients with severe leptospirosis and associated with disease severity
-
Goeijenbier M, Gasem MH, Meijers JC, Hartskeerl RA, Ahmed A, Goris MG, et al. Markers of endothelial cell activation and immune activation are increased in patients with severe leptospirosis and associated with disease severity. The Journal of infection. 2015.
-
(2015)
The Journal of infection
-
-
Goeijenbier, M.1
Gasem, M.H.2
Meijers, J.C.3
Hartskeerl, R.A.4
Ahmed, A.5
Goris, M.G.6
-
29
-
-
0036518150
-
Leptospirosis severity may be associated with the intensity of humoral immune response
-
12048544,.; (): –
-
Abdulkader RC, Daher EF, Camargo ED, Spinosa C, da Silva MV, Leptospirosis severity may be associated with the intensity of humoral immune response. Revista do Instituto de Medicina Tropical de Sao Paulo. 2002;44(2):79–83. 12048544
-
(2002)
Revista do Instituto de Medicina Tropical de Sao Paulo
, vol.44
, Issue.2
, pp. 79-83
-
-
Abdulkader, R.C.1
Daher, E.F.2
Camargo, E.D.3
Spinosa, C.4
da Silva, M.V.5
-
30
-
-
0032702291
-
Leptospiral outer membrane proteins OmpL1 and LipL41 exhibit synergistic immunoprotection
-
10569777,..; (): –. PubMed Central PMCID: PMC97069
-
Haake DA, Mazel MK, McCoy AM, Milward F, Chao G, Matsunaga J, et al. Leptospiral outer membrane proteins OmpL1 and LipL41 exhibit synergistic immunoprotection. Infection and immunity. 1999;67(12):6572–82. PubMed Central PMCID: PMC97069. 10569777
-
(1999)
Infection and immunity
, vol.67
, Issue.12
, pp. 6572-6582
-
-
Haake, D.A.1
Mazel, M.K.2
McCoy, A.M.3
Milward, F.4
Chao, G.5
Matsunaga, J.6
-
31
-
-
0017645569
-
Host immunological mechanisms in the resistance of mice to leptospiral infections
-
885617,.; (): –. PubMed Central PMCID: PMC421082
-
Adler B, Faine S, Host immunological mechanisms in the resistance of mice to leptospiral infections. Infection and immunity. 1977;17(1):67–72. PubMed Central PMCID: PMC421082. 885617
-
(1977)
Infection and immunity
, vol.17
, Issue.1
, pp. 67-72
-
-
Adler, B.1
Faine, S.2
-
32
-
-
70149110267
-
TLR4- and TLR2-mediated B cell responses control the clearance of the bacterial pathogen, Leptospira interrogans
-
19635914,..; (): –
-
Chassin C, Picardeau M, Goujon JM, Bourhy P, Quellard N, Darche S, et al. TLR4- and TLR2-mediated B cell responses control the clearance of the bacterial pathogen, Leptospira interrogans. J Immunol. 2009;183(4):2669–77. doi: 10.4049/jimmunol.090050619635914
-
(2009)
J Immunol
, vol.183
, Issue.4
, pp. 2669-2677
-
-
Chassin, C.1
Picardeau, M.2
Goujon, J.M.3
Bourhy, P.4
Quellard, N.5
Darche, S.6
-
33
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
19131956,.; (): –
-
Huang da W, Sherman BT, Lempicki RA, Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nature protocols. 2009;4(1):44–57. doi: 10.1038/nprot.2008.21119131956
-
(2009)
Nature protocols
, vol.4
, Issue.1
, pp. 44-57
-
-
Huang da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
34
-
-
58549112996
-
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
-
19033363,.; (): –. PubMed Central PMCID: PMC2615629
-
Huang da W, Sherman BT, Lempicki RA, Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic acids research. 2009;37(1):1–13. PubMed Central PMCID: PMC2615629. doi: 10.1093/nar/gkn92319033363
-
(2009)
Nucleic acids research
, vol.37
, Issue.1
, pp. 1-13
-
-
Huang da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
35
-
-
84883303075
-
Identifying key regulatory genes in the whole blood of septic patients to monitor underlying immune dysfunctions
-
23807251,..; (): –
-
Parnell GP, Tang BM, Nalos M, Armstrong NJ, Huang SJ, Booth DR, et al. Identifying key regulatory genes in the whole blood of septic patients to monitor underlying immune dysfunctions. Shock. 2013;40(3):166–74. doi: 10.1097/SHK.0b013e31829ee60423807251
-
(2013)
Shock
, vol.40
, Issue.3
, pp. 166-174
-
-
Parnell, G.P.1
Tang, B.M.2
Nalos, M.3
Armstrong, N.J.4
Huang, S.J.5
Booth, D.R.6
-
36
-
-
84857647499
-
Standardizing immunophenotyping for the Human Immunology Project
-
22343568,.; (): –. PubMed Central PMCID: PMC3409649
-
Maecker HT, McCoy JP, Nussenblatt R, Standardizing immunophenotyping for the Human Immunology Project. Nature reviews Immunology. 2012;12(3):191–200. PubMed Central PMCID: PMC3409649. doi: 10.1038/nri315822343568
-
(2012)
Nature reviews Immunology
, vol.12
, Issue.3
, pp. 191-200
-
-
Maecker, H.T.1
McCoy, J.P.2
Nussenblatt, R.3
-
37
-
-
84906790031
-
Javier Abello and Tonatiuh Melgarejo. Clinical Relevance of Cathelicidin in Infectious Disease
-
Annika Linde GHL, Javier Abello and Tonatiuh Melgarejo. Clinical Relevance of Cathelicidin in Infectious Disease. Journal of Clinical Cell Immunology. 2013;S13:003.
-
(2013)
Journal of Clinical Cell Immunology
, vol.S13
, pp. 003
-
-
Annika Linde, G.H.L.1
-
38
-
-
84923040341
-
Hepatocyte growth factor: A regulator of inflammation and autoimmunity
-
25476732,.; (): –
-
Molnarfi N, Benkhoucha M, Funakoshi H, Nakamura T, Lalive PH, Hepatocyte growth factor: A regulator of inflammation and autoimmunity. Autoimmunity reviews. 2015;14(4):293–303. doi: 10.1016/j.autrev.2014.11.01325476732
-
(2015)
Autoimmunity reviews
, vol.14
, Issue.4
, pp. 293-303
-
-
Molnarfi, N.1
Benkhoucha, M.2
Funakoshi, H.3
Nakamura, T.4
Lalive, P.H.5
-
39
-
-
84881023510
-
Plasma YKL-40 and CHI3L1 in systemic inflammation and sepsis-experience from two prospective cohorts
-
23706599,..; (): –
-
Kornblit B, Hellemann D, Munthe-Fog L, Bonde J, Strom JJ, Madsen HO, et al. Plasma YKL-40 and CHI3L1 in systemic inflammation and sepsis-experience from two prospective cohorts. Immunobiology. 2013;218(10):1227–34. doi: 10.1016/j.imbio.2013.04.01023706599
-
(2013)
Immunobiology
, vol.218
, Issue.10
, pp. 1227-1234
-
-
Kornblit, B.1
Hellemann, D.2
Munthe-Fog, L.3
Bonde, J.4
Strom, J.J.5
Madsen, H.O.6
-
40
-
-
84937702724
-
TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes
-
26101323,.; (): –
-
Eigenbrod T, Pelka K, Latz E, Kreikemeyer B, Dalpke AH, TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes. J Immunol. 2015;195(3):1092–9. doi: 10.4049/jimmunol.140317326101323
-
(2015)
J Immunol
, vol.195
, Issue.3
, pp. 1092-1099
-
-
Eigenbrod, T.1
Pelka, K.2
Latz, E.3
Kreikemeyer, B.4
Dalpke, A.H.5
-
41
-
-
84954373228
-
Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA
-
26545385,..; (): –. PubMed Central PMCID: PMC4687425
-
Kruger A, Oldenburg M, Chebrolu C, Beisser D, Kolter J, Sigmund AM, et al. Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA. EMBO Rep. 2015;16(12):1656–63. PubMed Central PMCID: PMC4687425. doi: 10.15252/embr.20154086126545385
-
(2015)
EMBO Rep
, vol.16
, Issue.12
, pp. 1656-1663
-
-
Kruger, A.1
Oldenburg, M.2
Chebrolu, C.3
Beisser, D.4
Kolter, J.5
Sigmund, A.M.6
-
42
-
-
70349245386
-
Bacterial RNA is recognized by different sets of immunoreceptors
-
19662634,.; (): –
-
Eberle F, Sirin M, Binder M, Dalpke AH, Bacterial RNA is recognized by different sets of immunoreceptors. Eur J Immunol. 2009;39(9):2537–47. doi: 10.1002/eji.20083897819662634
-
(2009)
Eur J Immunol
, vol.39
, Issue.9
, pp. 2537-2547
-
-
Eberle, F.1
Sirin, M.2
Binder, M.3
Dalpke, A.H.4
-
43
-
-
67349187318
-
Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells
-
19430477,..; (): –
-
Mancuso G, Gambuzza M, Midiri A, Biondo C, Papasergi S, Akira S, et al. Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells. Nat Immunol. 2009;10(6):587–94. doi: 10.1038/ni.173319430477
-
(2009)
Nat Immunol
, vol.10
, Issue.6
, pp. 587-594
-
-
Mancuso, G.1
Gambuzza, M.2
Midiri, A.3
Biondo, C.4
Papasergi, S.5
Akira, S.6
-
44
-
-
0036929153
-
Comparative in vitro activity of five cathelicidin-derived synthetic peptides against Leptospira, Borrelia and Treponema pallidum
-
12461010,..; (): –
-
Sambri V, Marangoni A, Giacani L, Gennaro R, Murgia R, Cevenini R, et al. Comparative in vitro activity of five cathelicidin-derived synthetic peptides against Leptospira, Borrelia and Treponema pallidum. J Antimicrob Chemother. 2002;50(6):895–902. 12461010
-
(2002)
J Antimicrob Chemother
, vol.50
, Issue.6
, pp. 895-902
-
-
Sambri, V.1
Marangoni, A.2
Giacani, L.3
Gennaro, R.4
Murgia, R.5
Cevenini, R.6
-
45
-
-
6444234288
-
Antimicrobial and Lipopolysaccharide-Binding Activities of C-terminal Domain of Human CAP18 Peptides to Genus Leptospira
-
Isogai E, M. H Isogai H, Matsuo K, Watarai S, Miura H, et al. Antimicrobial and Lipopolysaccharide-Binding Activities of C-terminal Domain of Human CAP18 Peptides to Genus Leptospira. The Journal of Applied Research. 2004;4(1):180–5.
-
(2004)
The Journal of Applied Research
, vol.4
, Issue.1
, pp. 180-185
-
-
Isogai, E.1
Isogai, H.2
Matsuo, K.3
Watarai, S.4
Miura, H.5
-
46
-
-
0006473918
-
The ratio of plasma levels of IL-10/TNF-alpha and its relationship to disease severity and survival in patients with leptospirosis
-
11105129,.; (): –
-
Tajiki MH, Satie Nakama A, Salomao R, The ratio of plasma levels of IL-10/TNF-alpha and its relationship to disease severity and survival in patients with leptospirosis. Braz J Infect Dis. 1997;1(3):138–41. 11105129
-
(1997)
Braz J Infect Dis
, vol.1
, Issue.3
, pp. 138-141
-
-
Tajiki, M.H.1
Satie Nakama, A.2
Salomao, R.3
-
47
-
-
59749089160
-
Evaluation of strategies for improving proteolytic resistance of antimicrobial peptides by using variants of EFK17, an internal segment of LL-37
-
19029324,.; (): –. PubMed Central PMCID: PMC2630634
-
Stromstedt AA, Pasupuleti M, Schmidtchen A, Malmsten M, Evaluation of strategies for improving proteolytic resistance of antimicrobial peptides by using variants of EFK17, an internal segment of LL-37. Antimicrob Agents Chemother. 2009;53(2):593–602. PubMed Central PMCID: PMC2630634. doi: 10.1128/AAC.00477-0819029324
-
(2009)
Antimicrob Agents Chemother
, vol.53
, Issue.2
, pp. 593-602
-
-
Stromstedt, A.A.1
Pasupuleti, M.2
Schmidtchen, A.3
Malmsten, M.4
-
48
-
-
85007199232
-
Treatment with LL-37 is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: a randomized, placebo-controlled clinical trial
-
25041740,.; (): –
-
Gronberg A, Mahlapuu M, Stahle M, Whately-Smith C, Rollman O, Treatment with LL-37 is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: a randomized, placebo-controlled clinical trial. Wound Repair Regen. 2014;22(5):613–21. doi: 10.1111/wrr.1221125041740
-
(2014)
Wound Repair Regen
, vol.22
, Issue.5
, pp. 613-621
-
-
Gronberg, A.1
Mahlapuu, M.2
Stahle, M.3
Whately-Smith, C.4
Rollman, O.5
-
49
-
-
85002264096
-
-
[18JUL2016]. Available from
-
Intratumoral Injections of LL37 for Melanoma https://clinicaltrials.gov/ct2/show/NCT02225366: M.D. Anderson Cancer Center; 2016 [18JUL2016]. Available from: https://clinicaltrials.gov/ct2/show/NCT02225366.
-
(2016)
-
-
-
50
-
-
84877036491
-
Diverse pathological implications of YKL-40: answers may lie in 'outside-in' signaling
-
23562456,..; (): –
-
Prakash M, Bodas M, Prakash D, Nawani N, Khetmalas M, Mandal A, et al. Diverse pathological implications of YKL-40: answers may lie in 'outside-in' signaling. Cellular signalling. 2013;25(7):1567–73. doi: 10.1016/j.cellsig.2013.03.01623562456
-
(2013)
Cellular signalling
, vol.25
, Issue.7
, pp. 1567-1573
-
-
Prakash, M.1
Bodas, M.2
Prakash, D.3
Nawani, N.4
Khetmalas, M.5
Mandal, A.6
-
51
-
-
84892867717
-
Interleukin-18, more than a Th1 cytokine
-
24275602,.; (): –
-
Novick D, Kim S, Kaplanski G, Dinarello CA, Interleukin-18, more than a Th1 cytokine. Seminars in immunology. 2013;25(6):439–48. doi: 10.1016/j.smim.2013.10.01424275602
-
(2013)
Seminars in immunology
, vol.25
, Issue.6
, pp. 439-448
-
-
Novick, D.1
Kim, S.2
Kaplanski, G.3
Dinarello, C.A.4
-
52
-
-
0033944073
-
Elevation of IL-18 in human sepsis
-
10941829,..; (): –
-
Grobmyer SR, Lin E, Lowry SF, Rivadeneira DE, Potter S, Barie PS, et al. Elevation of IL-18 in human sepsis. Journal of clinical immunology. 2000;20(3):212–5. 10941829
-
(2000)
Journal of clinical immunology
, vol.20
, Issue.3
, pp. 212-215
-
-
Grobmyer, S.R.1
Lin, E.2
Lowry, S.F.3
Rivadeneira, D.E.4
Potter, S.5
Barie, P.S.6
-
53
-
-
33644819168
-
Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit
-
16148039,.; (): –
-
Parikh CR, Abraham E, Ancukiewicz M, Edelstein CL, Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit. Journal of the American Society of Nephrology: JASN. 2005;16(10):3046–52. doi: 10.1681/ASN.200503023616148039
-
(2005)
Journal of the American Society of Nephrology: JASN
, vol.16
, Issue.10
, pp. 3046-3052
-
-
Parikh, C.R.1
Abraham, E.2
Ancukiewicz, M.3
Edelstein, C.L.4
-
54
-
-
0018039097
-
The antibodies involved in the human immune response to leptospiral infection
-
722781,.; (): –
-
Adler B, Faine S, The antibodies involved in the human immune response to leptospiral infection. Journal of medical microbiology. 1978;11(4):387–400. doi: 10.1099/00222615-11-4-387722781
-
(1978)
Journal of medical microbiology
, vol.11
, Issue.4
, pp. 387-400
-
-
Adler, B.1
Faine, S.2
-
55
-
-
0023035801
-
A monoclonal antibody reacting with a determinant on leptospiral lipopolysaccharide protects guinea pigs against leptospirosis
-
2430103,.; (): –
-
Jost BH, Adler B, Vinh T, Faine S, A monoclonal antibody reacting with a determinant on leptospiral lipopolysaccharide protects guinea pigs against leptospirosis. Journal of medical microbiology. 1986;22(3):269–75. doi: 10.1099/00222615-22-3-2692430103
-
(1986)
Journal of medical microbiology
, vol.22
, Issue.3
, pp. 269-275
-
-
Jost, B.H.1
Adler, B.2
Vinh, T.3
Faine, S.4
-
56
-
-
79952344765
-
Cross-protective immunity against leptospirosis elicited by a live, attenuated lipopolysaccharide mutant
-
21220775,..; (): –. PubMed Central PMCID: PMC3071135
-
Srikram A, Zhang K, Bartpho T, Lo M, Hoke DE, Sermswan RW, et al. Cross-protective immunity against leptospirosis elicited by a live, attenuated lipopolysaccharide mutant. J Infect Dis. 2011;203(6):870–9. PubMed Central PMCID: PMC3071135. doi: 10.1093/infdis/jiq12721220775
-
(2011)
J Infect Dis
, vol.203
, Issue.6
, pp. 870-879
-
-
Srikram, A.1
Zhang, K.2
Bartpho, T.3
Lo, M.4
Hoke, D.E.5
Sermswan, R.W.6
-
57
-
-
58149123710
-
Monoclonal antibodies to LipL32 protect against heterologous Leptospira spp. challenge
-
Maneewatch S, Sakolvaree Y, Saengjaruk P, Srimanote P, Tapchaisri P, Tongtawe P, et al. Monoclonal antibodies to LipL32 protect against heterologous Leptospira spp. challenge. Hybridoma (Larchmt). 2008;27(6):453–65.
-
(2008)
Hybridoma (Larchmt)
, vol.27
, Issue.6
, pp. 453-465
-
-
Maneewatch, S.1
Sakolvaree, Y.2
Saengjaruk, P.3
Srimanote, P.4
Tapchaisri, P.5
Tongtawe, P.6
-
58
-
-
84907587756
-
Human leptospirosis: seroreactivity and genetic susceptibility in the population of Sao Miguel Island (Azores, Portugal)
-
25255143,..; ():. PubMed Central PMCID: PMC4177921
-
Esteves LM, Bulhoes SM, Branco CC, Mota FM, Paiva C, Cabral R, et al. Human leptospirosis: seroreactivity and genetic susceptibility in the population of Sao Miguel Island (Azores, Portugal). PLoS One. 2014;9(9):e108534. PubMed Central PMCID: PMC4177921. doi: 10.1371/journal.pone.010853425255143
-
(2014)
PLoS One
, vol.9
, Issue.9
, pp. e108534
-
-
Esteves, L.M.1
Bulhoes, S.M.2
Branco, C.C.3
Mota, F.M.4
Paiva, C.5
Cabral, R.6
-
59
-
-
3242747467
-
HLA-DQ6 and ingestion of contaminated water: possible gene-environment interaction in an outbreak of Leptospirosis
-
15014429,..; (): –
-
Lingappa J, Kuffner T, Tappero J, Whitworth W, Mize A, Kaiser R, et al. HLA-DQ6 and ingestion of contaminated water: possible gene-environment interaction in an outbreak of Leptospirosis. Genes Immun. 2004;5(3):197–202. doi: 10.1038/sj.gene.636405815014429
-
(2004)
Genes Immun
, vol.5
, Issue.3
, pp. 197-202
-
-
Lingappa, J.1
Kuffner, T.2
Tappero, J.3
Whitworth, W.4
Mize, A.5
Kaiser, R.6
-
60
-
-
67349163028
-
Detection of pathogenic Leptospira spp. through TaqMan polymerase chain reaction targeting the LipL32 gene
-
19395218,.; (): –
-
Stoddard RA, Gee JE, Wilkins PP, McCaustland K, Hoffmaster AR, Detection of pathogenic Leptospira spp. through TaqMan polymerase chain reaction targeting the LipL32 gene. Diagnostic microbiology and infectious disease. 2009;64(3):247–55. doi: 10.1016/j.diagmicrobio.2009.03.01419395218
-
(2009)
Diagnostic microbiology and infectious disease
, vol.64
, Issue.3
, pp. 247-255
-
-
Stoddard, R.A.1
Gee, J.E.2
Wilkins, P.P.3
McCaustland, K.4
Hoffmaster, A.R.5
-
61
-
-
2942625703
-
A quantitative PCR (TaqMan) assay for pathogenic Leptospira spp
-
12100734,..;:. PubMed Central PMCID: PMC117785
-
Smythe LD, Smith IL, Smith GA, Dohnt MF, Symonds ML, Barnett LJ, et al. A quantitative PCR (TaqMan) assay for pathogenic Leptospira spp. BMC infectious diseases. 2002;2:13. PubMed Central PMCID: PMC117785. doi: 10.1186/1471-2334-2-1312100734
-
(2002)
BMC infectious diseases
, vol.2
, pp. 13
-
-
Smythe, L.D.1
Smith, I.L.2
Smith, G.A.3
Dohnt, M.F.4
Symonds, M.L.5
Barnett, L.J.6
-
62
-
-
62049084378
-
Research electronic data capture (REDCap)—a metadata-driven methodology and workflow process for providing translational research informatics support
-
18929686,.; (): –. PubMed Central PMCID: PMC2700030
-
Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG, Research electronic data capture (REDCap)—a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377–81. PubMed Central PMCID: PMC2700030. doi: 10.1016/j.jbi.2008.08.01018929686
-
(2009)
J Biomed Inform
, vol.42
, Issue.2
, pp. 377-381
-
-
Harris, P.A.1
Taylor, R.2
Thielke, R.3
Payne, J.4
Gonzalez, N.5
Conde, J.G.6
-
63
-
-
84961347404
-
Spatiotemporal Determinants of Urban Leptospirosis Transmission: Four-Year Prospective Cohort Study of Slum Residents in Brazil
-
26771379,..; ():. PubMed Central PMCID: PMC4714915
-
Hagan JE, Moraga P, Costa F, Capian N, Ribeiro GS, Wunder EA, Jr.et al. Spatiotemporal Determinants of Urban Leptospirosis Transmission: Four-Year Prospective Cohort Study of Slum Residents in Brazil. PLoS neglected tropical diseases. 2016;10(1):e0004275. PubMed Central PMCID: PMC4714915. doi: 10.1371/journal.pntd.000427526771379
-
(2016)
PLoS neglected tropical diseases
, vol.10
, Issue.1
, pp. e0004275
-
-
Hagan, J.E.1
Moraga, P.2
Costa, F.3
Capian, N.4
Ribeiro, G.S.5
Wunder, E.A.6
-
64
-
-
84926507971
-
limma powers differential expression analyses for RNA-sequencing and microarray studies
-
Ritchie ME, Phipson B, Wu D, Hu Y, Law CW, Shi W, et al. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic acids research. 2015.
-
(2015)
Nucleic acids research
-
-
Ritchie, M.E.1
Phipson, B.2
Wu, D.3
Hu, Y.4
Law, C.W.5
Shi, W.6
-
65
-
-
84874271270
-
NCBI GEO: archive for functional genomics data sets—update
-
23193258,..; (Database issue): –. PubMed Central PMCID: PMC3531084
-
Barrett T, Wilhite SE, Ledoux P, Evangelista C, Kim IF, Tomashevsky M, et al. NCBI GEO: archive for functional genomics data sets—update. Nucleic acids research. 2013;41(Database issue):D991–5. PubMed Central PMCID: PMC3531084. doi: 10.1093/nar/gks119323193258
-
(2013)
Nucleic acids research
, vol.41
, pp. D991-D995
-
-
Barrett, T.1
Wilhite, S.E.2
Ledoux, P.3
Evangelista, C.4
Kim, I.F.5
Tomashevsky, M.6
-
66
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
11309499,.; (): –. PubMed Central PMCID: PMC33173
-
Tusher VG, Tibshirani R, Chu G, Significance analysis of microarrays applied to the ionizing radiation response. Proceedings of the National Academy of Sciences of the United States of America. 2001;98(9):5116–21. PubMed Central PMCID: PMC33173. doi: 10.1073/pnas.09106249811309499
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.9
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
67
-
-
0034730140
-
Singular value decomposition for genome-wide expression data processing and modeling
-
10963673,.; (): –. PubMed Central PMCID: PMC27718
-
Alter O, Brown PO, Botstein D, Singular value decomposition for genome-wide expression data processing and modeling. Proceedings of the National Academy of Sciences of the United States of America. 2000;97(18):10101–6. PubMed Central PMCID: PMC27718. 10963673
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.18
, pp. 10101-10106
-
-
Alter, O.1
Brown, P.O.2
Botstein, D.3
-
68
-
-
40449126165
-
Gene-expression patterns reveal underlying biological processes in Kawasaki disease
-
18067656,..; ():. PubMed Central PMCID: PMC2246263
-
Popper SJ, Shimizu C, Shike H, Kanegaye JT, Newburger JW, Sundel RP, et al. Gene-expression patterns reveal underlying biological processes in Kawasaki disease. Genome biology. 2007;8(12):R261. PubMed Central PMCID: PMC2246263. doi: 10.1186/gb-2007-8-12-r26118067656
-
(2007)
Genome biology
, vol.8
, Issue.12
, pp. R261
-
-
Popper, S.J.1
Shimizu, C.2
Shike, H.3
Kanegaye, J.T.4
Newburger, J.W.5
Sundel, R.P.6
-
69
-
-
84876581893
-
InnateDB: systems biology of innate immunity and beyond—recent updates and continuing curation
-
23180781,..; (Database issue): –. PubMed Central PMCID: PMC3531080
-
Breuer K, Foroushani AK, Laird MR, Chen C, Sribnaia A, Lo R, et al. InnateDB: systems biology of innate immunity and beyond—recent updates and continuing curation. Nucleic acids research. 2013;41(Database issue):D1228–33. PubMed Central PMCID: PMC3531080. doi: 10.1093/nar/gks114723180781
-
(2013)
Nucleic acids research
, vol.41
, pp. D1228-D1233
-
-
Breuer, K.1
Foroushani, A.K.2
Laird, M.R.3
Chen, C.4
Sribnaia, A.5
Lo, R.6
-
70
-
-
84920511159
-
Systems immunology reveals markers of susceptibility to West Nile virus infection
-
25355795,..; (): –. PubMed Central PMCID: PMC4278927
-
Qian F, Goel G, Meng H, Wang X, You F, Devine L, et al. Systems immunology reveals markers of susceptibility to West Nile virus infection. Clinical and vaccine immunology: CVI. 2015;22(1):6–16. PubMed Central PMCID: PMC4278927. doi: 10.1128/CVI.00508-1425355795
-
(2015)
Clinical and vaccine immunology: CVI
, vol.22
, Issue.1
, pp. 6-16
-
-
Qian, F.1
Goel, G.2
Meng, H.3
Wang, X.4
You, F.5
Devine, L.6
-
71
-
-
84903703398
-
Automated identification of stratifying signatures in cellular subpopulations
-
24979804,.; (): –. PubMed Central PMCID: PMC4084463
-
Bruggner RV, Bodenmiller B, Dill DL, Tibshirani RJ, Nolan GP, Automated identification of stratifying signatures in cellular subpopulations. Proceedings of the National Academy of Sciences of the United States of America. 2014;111(26):E2770–7. PubMed Central PMCID: PMC4084463. doi: 10.1073/pnas.140879211124979804
-
(2014)
Proceedings of the National Academy of Sciences of the United States of America
, vol.111
, Issue.26
, pp. E2770-E2777
-
-
Bruggner, R.V.1
Bodenmiller, B.2
Dill, D.L.3
Tibshirani, R.J.4
Nolan, G.P.5
-
72
-
-
46349105015
-
Characterization of virulence of Leptospira isolates in a hamster model
-
18547690,..; (): –. PubMed Central PMCID: PMC2519131
-
Silva EF, Santos CS, Athanazio DA, Seyffert N, Seixas FK, Cerqueira GM, et al. Characterization of virulence of Leptospira isolates in a hamster model. Vaccine. 2008;26(31):3892–6. PubMed Central PMCID: PMC2519131. doi: 10.1016/j.vaccine.2008.04.08518547690
-
(2008)
Vaccine
, vol.26
, Issue.31
, pp. 3892-3896
-
-
Silva, E.F.1
Santos, C.S.2
Athanazio, D.A.3
Seyffert, N.4
Seixas, F.K.5
Cerqueira, G.M.6
-
73
-
-
84976871046
-
Real-Time PCR Reveals Rapid Dissemination of Leptospira interrogans after Intraperitoneal and Conjunctival Inoculation of Hamsters
-
27141082,..; (): –. PubMed Central PMCID: PMC4936353
-
Wunder EA, Jr.Figueira CP, Santos GR, Lourdault K, Matthias MA, Vinetz JM, et al. Real-Time PCR Reveals Rapid Dissemination of Leptospira interrogans after Intraperitoneal and Conjunctival Inoculation of Hamsters. Infection and immunity. 2016;84(7):2105–15. PubMed Central PMCID: PMC4936353. doi: 10.1128/IAI.00094-1627141082
-
(2016)
Infection and immunity
, vol.84
, Issue.7
, pp. 2105-2115
-
-
Wunder, E.A.1
Figueira, C.P.2
Santos, G.R.3
Lourdault, K.4
Matthias, M.A.5
Vinetz, J.M.6
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