Synergistic anti-cancer effects of galangin and berberine through apoptosis induction and proliferation inhibition in oesophageal carcinoma cells

Biomedicine and Pharmacotherapy

Volumn 84, Issue , 2016, Pages 1748-1759

  Ren, Kewei ^a   Zhang, Wenzhe ^a   Wu, Gang ^a   Ren, Jianzhuang ^a   Lu, Huibin ^a   Li, Zongming ^a   Han, Xinwei ^a,b,c  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^b Interventional Therapy and Clinical Research Center of Henan Province   (China)

^c ZHENGZHOU UNIVERSITY   (China)

Author keywords

Berberine; Combination; Galangin; Oesophageal carcinoma

Indexed keywords

ANTINEOPLASTIC AGENT; BERBERINE; BETA CATENIN; CASPASE 3; CYCLIN B; CYCLIN D; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN E; GALANGIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; JANUS KINASE 2; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; PROTEIN P21; PROTEIN P27; PROTEIN P53; RAC PROTEIN; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; WNT3A PROTEIN; X LINKED INHIBITOR OF APOPTOSIS; CTNNB1 PROTEIN, HUMAN; FLAVONOID; WNT3A PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DEATH; CELL DENSITY; CELL MIGRATION; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG POTENTIATION; ESOPHAGEAL CANCER CELL LINE; ESOPHAGUS CARCINOMA; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SPINDLE CELL; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CARCINOMA, SQUAMOUS CELL; DRUG EFFECTS; DRUG SCREENING; ESOPHAGEAL NEOPLASMS; GENETIC TRANSFECTION; GENETICS; METABOLISM; NUDE MOUSE; OXIDATIVE STRESS; PATHOLOGY; RNA INTERFERENCE; TIME FACTOR; TUMOR CELL LINE; TUMOR VOLUME; WNT SIGNALING PATHWAY;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BERBERINE; BETA CATENIN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ESOPHAGEAL NEOPLASMS; FLAVONOIDS; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; MALE; MICE, INBRED BALB C; MICE, NUDE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; TIME FACTORS; TRANSFECTION; TUMOR BURDEN; WNT SIGNALING PATHWAY; WNT3A PROTEIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 85001070774     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2016.10.111     Document Type: Article

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