Inhibitory effect of the plant flavonoid galangin on rat vas deferens in vitro

Life Sciences

Volumn 72, Issue 26, 2003, Pages 2993-3001

  Capasso, Raffaele ^a,b   Mascolo, Nicola ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Flavonoids; Galangin; Neurotrasmission; Vanilloid (capsaicin) receptors; Vas deferens

Indexed keywords

ATROPINE; CAPSAZEPINE; GALANGIN; HEXAMETHONIUM; N(G) NITROARGININE METHYL ESTER; NALOXONE; NOLPITANTIUM; OSANETANT; SAREDUTANT; VANILLOID RECEPTOR; YOHIMBINE;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ELECTROSTIMULATION; IN VITRO STUDY; ISOLATED ORGAN; MALE; MINIMUM INHIBITORY CONCENTRATION; NEUROTRANSMISSION; NONHUMAN; RAT; SMOOTH MUSCLE CONTRACTION; VAS DEFERENS;

ANIMALIA; EMBRYOPHYTA;

EID: 0037449061     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(03)00232-7     Document Type: Article

References (39)

1. Amoros M., Lurton E., Boustie J., Girre L. Comparison of the anti-herpes simplex virus activities of propolis and 3-methyl-but-2-enyl caffeate. Journal of Natural Products. 57(5):1994;644-647.
2. Begg M., Molleman A., Parsons M. Modulation of the release of endogenous gamma-aminobutyric acid by cannabinoids in the guinea pig ileum. European Journal of Pharmacology. 434(1-2):2002;87-94.
3. Bevan S.J., Hothi S., Hughes G., James I.F., Rang H.P., Shah K., Walpole C.S.J., Yeats J.C. Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin. British Journal of Pharmacology. 107(2):1992;544-552.
4. 1 metabolism in human liver microsomes by naturally occurring flavonoids. Cancer Research. 41(1):1981;67-72.
5. Capasso R., Tavares I.A. Effect of the flavonoid galangin on urinary bladder rat contractility in vitro. Journal of Pharmacy and Pharmacology. 54(8):2002;1147-1150.
6. 4-induced microsomal lipid peroxidation. Experientia. 47(2):1991;195-199.
7. Ciolino H.P., Yeh G.C. The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the arly hidrocarbon receptor. British Journal of Cancer. 79(9-10):1999;1340-1346.
8. Denny B.J., Lambert P.A., West P.W.J. The flavonoid galangin inhibits the L1 metallo-β-lactamase from Stenotrophomonas maltophilia. FEMS Microbiology Letters. 208(1):2002;21-24.
9. Di Carlo G., Mascolo N., Izzo A.A., Capasso F. Flavonoids: old and new aspects of a class of natural therapeutic drugs. Life Sciences. 65(4):1999;337-353.
10. Gabor M., Razga Z. Effect of benzopyrone derivatives on simultaneously induced croton oil ear oedema and carrageenin paw oedema in rats. Acta Physiologica Hungarica. 77(3-4):1991;197-207.
11. Heo M.Y., Yu K.S., Kim K.H., Kim H.P., Au W.W. Anticlastogenic effect of flavonoids against mutagen-induced micronuclei in mice. Mutation Research. 284(2):1992;243-249.
12. Heo M.Y., Lee S.J., Kwon C.H., Kim S.W., Sohn D.H., Au W.W. Anticlastogenic effects of galangin against bleomycin-induced chromosomal aberration in mouse spleen lymphocytes. Mutation Research. 311(2):1994;225-229.
13. Heo M.Y., Jae L.H., Jung S.S., Au W.W. Anticlastogenic effects of galangin against mitomycin C-induced micronuclei in reticulocytes of mice. Mutation Research. 360(1):1996;37-41.
14. Heo M.Y., Sohn S.J., Au W.W. Anti-genotoxicity of galangin as a cancer chemopreventive agent candidate. Mutation Research. 488(2):2001;135-150.
15. Horvathova K., Vachalkova A., Novotny L. Flavonoids as the chemoprotective agents for civilitation diseases. Neoplasma. 48(6):2001;435-441.
16. Hughes J., Kosterlitz H.W., Leslie F.M. Effect of morphine on adrenergic transmission in the mouse vas deferens. Assessment of agonist and antagonist potencies of narcotic analgesics. British Journal of Pharmacology. 53(3):1975;371-381.
17. Imamura Y., Migita T., Uriu Y., Otagiri M., Okawara T. Inhibitory effects of flavonoids on rabbit heart carbonyl reductase. Journal of Biochemistry. 127(4):2000;653-658.
18. 1 receptors. British Journal of Pharmacology. 124(7):1998;1363-1368.
19. Izzo A.A., Mascolo N., Capasso F. Effect of selective phosphodiesterase inhibitors on synaptic transmission in the guinea-pig ileum. Naunyn Schmiedeberg's Archives Pharmacology. 357(6):1998;677-681.
20. Kang S.S., Kim J.S., Son K.M., Kim H.P., Chang H.W. Isolation of COX-2 inhibitors from Alpinia officinarum. Korean Journal of Pharmacognosy. 31:2000;57-62.
21. Maggi C.A., Bevan S., Walpole C.S.J., Rang H.P., Giuliani S. A comparation of capsazepine and ruthenium red as capsaicin antagonists in the rat isolated urinary bladder and vas deferens. British Journal of Pharmacology. 108(3):1993;801-805.
22. Maggi C.A., Patacchini R., Tramontana M., Amman R., Giuliani S., Santicioli P. Similarities and differences in the action of resiniferatoxin and capsaicin on central and peripheral endings of primary sensory neurons. Neuroscience. 37(2):1990;531-539.
23. Meyer J.J., Afolayan A.J., Taylor M.B., Erasmus D. Antiviral activity of galangin isolated from the aerial parts of Helichrysum aureonitens. Journal of Ethopharmacology. 56(2):1997;165-169.
24. Morimoto H., Murai M., Maeda Y., Yamaoka M., Nishikawa M., Kiyotoh S., Fujii T. FK 224,a novel cyclopeptide substances P antagonist with NK1 and NK2 receptor selectivity. Journal of Pharmacology and Experimental Therapeutics. 262(1):1992;398-402.
25. Nocerino E., Izzo A.A., Borrelli F., Capasso F., Capasso R., Pinto A., Sautebin L., Mascolo N. Relaxant effect of capsazepine in the isolated rat ileum. Naunyn Schmiedeberg's Archives Pharmacology. 365(3):2002;187-192.
26. Parlani M., Conte B., Goso C., Szallasi A., Manzini S. Capsaicin-induced relaxation in the rat isolated external urethral sphincter: characterization of the vanilloid receptor and mediation by CGRP. British Journal of Pharmacology. 110(3):1993;989-994.
27. Park Y.K., Koo M.H., Sato H.H., Contado J.L. Survey of some components of propolis which were collected by Apis mellifera in Brazil. Archives of Biological Technology. 38:1995;1253-1259.
28. Postorino A., Vetri T., Leggio L., Serio R., Bonvissuto F. Nitric oxide as neuromodulator of sympathetic transmission in rat vas deferens. Journal of Autonomic Pharmacology. 18(1):1998;21-29.
29. Rice-Evans C., Miller N.J., Paganga G. Antioxidant propriertes of phenolic compounds. Trends in Plant Science. 2:1997;152-159.
30. Ross R.A., Gibson T.M., Brockie H.C., Leslie M., Pashmi G., Craib S.J., Di Marzo V., Pertwee R.G. Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens. British Journal of Pharmacology. 132(3):2001;631-640.
31. Santicioli P., Maggi C.A., Geppetti P., Del Bianco E., Theodorsson E., Meli A. Release of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) from organs of the genitourinary tract in rats. Neuroscience Letters. 92(2):1988;197-201.
32. Shih H., Pickwell G.V., Quattrochi L.C. Differential effects of flavonoid compounds on tumor promoter-induced activation of the human CYP1A2 enhancer. Archives of Biochemistry and Biophysics. 373(1):2000;287-294.
33. So F.V., Guthrie N., Chambers A.F., Carroll K.K. Inhibition of proliferation of estrogen receptor-positive MCF-7 human breast cancer cells by flavonoids in the presence and absence of excess estrogen. Cancer Letters. 112(2):1997;127-133.
34. Sohn S.J., Huh I.H., Au W.W., Heo M.Y. Antigenotoxicity of galangin against N-methyl-N-nitrosourea. Mutation Research. 402(1-2):1998;231-236.
35. Szallasi A., Di Marzo V. New perspectives on enigmatic vanilloid receptor. Trends Neuroscience. 23(3):2000;491-497.
36. Wall M.E., Wani M.C., Manikumar G., Abraham P., Taylor H., Hughes T.J., Warner J., McGivney R. Plant antimutagenic agents. 2. Flavonoids. Journal of Natural Products. 51(6):1988;1084-1091.
37. Wardle K.A., Furey G., Sanger G.J. Pharmacological characterization of the vanilloid receptor in the rat isolated vas deferens. Journal of Pharmacy and Pharmacology. 48(3):1996;285-291.
38. Westfall T.D., Westfall D.P. Pharmacological techniques for the in vitro study of the vas deferens. Journal of Pharmacology and Toxicology Methods. 45(2):2001;109-122.
39. Xi Q., Angus J.A. Evidence against an action of mibefradil at N-type voltage-operated calcium channels. Naunyn Schmiedeberg's Archives Pharmacology. 364(5):2001;430-436.