Microvascular monitoring – Do ‘global’ markers help?

Best Practice and Research: Clinical Anaesthesiology

Volumn 30, Issue 4, 2016, Pages 399-405

  Vincent, Jean Louis ^a   Taccone, Fabio Silvio ^a  

^a ERASME HOSPITAL   (Belgium)

Author keywords

adrenergic agents; drotrecogin alfa; endothelial cells; nitrates; PCO2 gradients; septic shock

Indexed keywords

CORTICOSTEROID; DROTRECOGIN; MARKER; NITRIC OXIDE; VASOACTIVE AGENT;

ARTERIAL PRESSURE; BLOOD TRANSFUSION; CAPILLARY DENSITY; CRITICALLY ILL PATIENT; HEART OUTPUT; HEMODYNAMICS; HUMAN; MEAN ARTERIAL PRESSURE; MICROCIRCULATION; MICROVASCULARIZATION; MICROVASCULATURE; OUTCOME ASSESSMENT; OXYGEN SATURATION; PRIORITY JOURNAL; REVIEW; SEPSIS; SYSTEMIC CIRCULATION; VENOUS OXYGEN TENSION; PHYSIOLOGIC MONITORING; PHYSIOLOGY; STANDARDS;

ARTERIAL PRESSURE; CARDIAC OUTPUT; HEMODYNAMICS; HUMANS; MICROCIRCULATION; MONITORING, PHYSIOLOGIC;

EID: 85000963160     PISSN: 15216896     EISSN: 1532169X     Source Type: Journal    
DOI: 10.1016/j.bpa.2016.10.006     Document Type: Review

References (47)

1. [1] Vincent, J.L., De Backer, D., Circulatory shock. N Engl J Med 369 (2013), 1726–1734.
2. [2] De Backer, D., Donadello, K., Sakr, Y., et al. Microcirculatory alterations in patients with severe sepsis: impact of time of assessment and relationship with outcome. Crit Care Med 41 (2013), 791–799.
3. [3] Edul, V.S., Ince, C., Vazquez, A.R., et al. Similar microcirculatory alterations in patients with normodynamic and hyperdynamic septic shock. Ann Am Thorac Soc 13 (2016), 240–247.
4. [4] Ince, C., The microcirculation is the motor of sepsis. Crit Care 9:Suppl. 4 (2005), S13–S19.
5. [5] De Backer, D., Donadello, K., Taccone, F.S., et al. Microcirculatory alterations: potential mechanisms and implications for therapy. Ann Intensive Care, 1, 2011, 27.
6. [6] Weil, M.H., Shubin, H., Proposed reclassification of shock states with special reference to distributive defects. Adv Exp Med Biol 23 (1971), 13–23.
7. [7] Ospina-Tascon, G.A., Umana, M., Bermudez, W.F., et al. Can venous-to-arterial carbon dioxide differences reflect microcirculatory alterations in patients with septic shock?. Intensive Care Med 42 (2016), 211–221.
8. [8] De Backer, D., Orbegozo, D., Donadello, K., et al. Pathophysiology of microcirculatory dysfunction and the pathogenesis of septic shock. Virulence 5 (2014), 73–79.
9. [9] De Backer, D., Creteur, J., Preiser, J.C., et al. Microvascular blood flow is altered in patients with sepsis. Am J Respir Crit Care Med 166 (2002), 98–104.
10. [10] Sakr, Y., Dubois, M.J., De Backer, D., et al. Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med 32 (2004), 1825–1831.
11. [11] Trzeciak, S., McCoy, J.V., Phillip, D.R., et al. Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis. Intensive Care Med 34 (2008), 2210–2217.
12. [12] Dubin, A., Pozo, M.O., Casabella, C.A., et al. Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study. Crit Care, 13, 2009, R92.
13. [13] Morelli, A., Donati, A., Ertmer, C., et al. Short-term effects of terlipressin bolus infusion on sublingual microcirculatory blood flow during septic shock. Intensive Care Med 37 (2011), 963–969.
14. [14] Morelli, A., Donati, A., Ertmer, C., et al. Effects of vasopressinergic receptor agonists on sublingual microcirculation in norepinephrine-dependent septic shock. Crit Care, 15, 2011, R217.
15. [15] Morelli, A., Donati, A., Ertmer, C., et al. Levosimendan for resuscitating the microcirculation in patients with septic shock: a randomized controlled study. Crit Care, 14, 2010, R232.
16. [16] Creteur, J., De Backer, D., Sakr, Y., et al. Sublingual capnometry tracks microcirculatory changes in septic patients. Intensive Care Med 32 (2006), 516–523.
17. [17] Habicher, M., von Heymann, C., Spies, C.D., et al. Central venous-arterial pCO2 difference identifies microcirculatory hypoperfusion in cardiac surgical patients with normal central venous oxygen saturation: a retrospective analysis. J Cardiothorac Vasc Anesth 29 (2015), 646–655.
18. [18] Vincent, J.L., Quintairos, E. Silva, Couto, L. Jr., et al. The value of blood lactate kinetics in critically ill patients: a systematic review. Crit Care, 20, 2016, 257.
19. [19] Vincent, J.L., Lactic acidosis. N Engl J Med 372 (2015), 1077–1078.
20. [20] Vincent, J.L., Serial blood lactate levels reflect both lactate production and clearance. Crit Care Med, 43, 2015, e209.
21. [21] Puskarich, M.A., Shapiro, N.I., Massey, M.J., et al. Lactate clearance in septic shock is not a surrogate for improved microcirculatory flow. Acad Emerg Med 23 (2016), 690–693.
22. [22] Ospina-Tascon, G., Neves, A.P., Occhipinti, G., et al. Effects of fluids on microvascular perfusion in patients with severe sepsis. Intensive Care Med 36 (2010), 949–955.
23. [23] Pranskunas, A., Koopmans, M., Koetsier, P.M., et al. Microcirculatory blood flow as a tool to select ICU patients eligible for fluid therapy. Intensive Care Med 39 (2013), 612–619.
24. [24] Dubin, A., Pozo, M.O., Casabella, C.A., et al. Comparison of 6% hydroxyethyl starch 130/0.4 and saline solution for resuscitation of the microcirculation during the early goal-directed therapy of septic patients. J Crit Care, 25, 2010 659.e1-8.
25. [25] Sakr, Y., Chierego, M., Piagnerelli, M., et al. Microvascular response to red blood cell transfusion in patients with severe sepsis. Crit Care Med 35 (2007), 1639–1644.
26. [26] Creteur, J., Neves, A.P., Vincent, J.L., Near-infrared spectroscopy technique to evaluate the effects of red blood cell transfusion on tissue oxygenation. Crit Care, 13(Suppl. 5), 2009, S11.
27. [27] Sadaka, F., Aggu-Sher, R., Krause, K., et al. The effect of red blood cell transfusion on tissue oxygenation and microcirculation in severe septic patients. Ann Intensive Care, 1, 2011, 46.
28. [28] Yuruk, K., Almac, E., Bezemer, R., et al. Blood transfusions recruit the microcirculation during cardiac surgery. Transfusion 51 (2011), 961–967.
29. [29] Xu, J.Y., Ma, S.Q., Pan, C., et al. A high mean arterial pressure target is associated with improved microcirculation in septic shock patients with previous hypertension: a prospective open label study. Crit Care, 19, 2015, 130.
30. [30] Maier, S., Hasibeder, W.R., Hengl, C., et al. Effects of phenylephrine on the sublingual microcirculation during cardiopulmonary bypass. Br J Anaesth 102 (2009), 485–491.
31. [31] Jhanji, S., Stirling, S., Patel, N., et al. The effect of increasing doses of norepinephrine on tissue oxygenation and microvascular flow in patients with septic shock. Crit Care Med 37 (2009), 1961–1966.
32. [32] Thooft, A., Favory, R., Salgado, D.R., et al. Effects of changes in arterial pressure on organ perfusion during septic shock. Crit Care, 15, 2011, R222.
33. [33] Spronk, P.E., Ince, C., Gardien, M.J., et al. Nitroglycerin in septic shock after intravascular volume resuscitation. Lancet 360 (2002), 1395–1396.
34. [34] Boerma, E.C., Koopmans, M., Konijn, A., et al. Effects of nitroglycerin on sublingual microcirculatory blood flow in patients with severe sepsis/septic shock after a strict resuscitation protocol: a double-blind randomized placebo controlled trial. Crit Care Med 38 (2010), 93–100.
35. [35] De Backer, D., Creteur, J., Dubois, M.J., et al. The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects. Crit Care Med 34 (2006), 403–408.
36. [36] He, X., Su, F., Velissaris, D., et al. Administration of tetrahydrobiopterin improves the microcirculation and outcome in an ovine model of septic shock. Crit Care Med 40 (2012), 2833–2840.
37. [37] Buchele, G.L., Silva, E., Ospina-Tascon, G.A., et al. Effects of hydrocortisone on microcirculatory alterations in patients with septic shock. Crit Care Med 37 (2009), 1341–1347.
38. [38] De Backer, D., Verdant, C., Chierego, M., et al. Effects of drotrecogin alfa activated on microcirculatory alterations in patients with severe sepsis. Crit Care Med 34 (2006), 1918–1924.
39. [39] Masip, J., Mesquida, J., Luengo, C., et al. Near-infrared spectroscopy StO2 monitoring to assess the therapeutic effect of drotrecogin alfa (activated) on microcirculation in patients with severe sepsis or septic shock. Ann Intensive Care, 3, 2013, 30.
40. [40] Lamblin, V., Favory, R., Boulo, M., et al. Microcirculatory alterations induced by sedation in intensive care patients. Effects of midazolam alone and in association with sufentanil. Crit Care, 10, 2006, R176.
41. [41] Koch, M., De Backer, D., Vincent, J.L., et al. Effects of propofol on human microcirculation. Br J Anaesth 101 (2008), 473–478.
42. [42] Miranda, M.L., Balarini, M.M., Bouskela, E., Dexmedetomidine attenuates the microcirculatory derangements evoked by experimental sepsis. Anesthesiology 122 (2015), 619–630.
43. [43] Liu, X., Zhang, K., Wang, W., et al. Dexmedetomidine versus propofol sedation improves sublingual microcirculation after cardiac surgery: a randomized controlled trial. J Cardiothorac Vasc Anesth, 2016, 10.1053/j.jvca.2016.05.038 (in press).
44. [44] Verdant, C.L., De Backer, D., Bruhn, A., et al. Evaluation of sublingual and gut mucosal microcirculation in sepsis: a quantitative analysis. Crit Care Med 37 (2009), 2875–2881.
45. [45] Boerma, E.C., van der Voort, P.H., Spronk, P.E., et al. Relationship between sublingual and intestinal microcirculatory perfusion in patients with abdominal sepsis. Crit Care Med 35 (2007), 1055–1060.
46. [46] Gilbert-Kawai, E., Coppel, J., Bountziouka, V., et al. A comparison of the quality of image acquisition between the incident dark field and sidestream dark field video-microscopes. BMC Med Imaging, 16, 2016, 10.
47. [47] Tanaka, S., Harrois, A., Nicolai, C., et al. Qualitative real-time analysis by nurses of sublingual microcirculation in intensive care unit: the MICRONURSE study. Crit Care, 19, 2015, 388.