Microcirculatory blood flow as a tool to select ICU patients eligible for fluid therapy

Intensive Care Medicine

Volumn 39, Issue 4, 2013, Pages 612-619

  Pranskunas, Andrius ^a   Koopmans, Matty ^b   Koetsier, Peter M ^b   Pilvinis, Vidas ^a   Boerma, E Christiaan ^b,c  

^a LITHUANIAN UNIVERSITY OF HEALTH SCIENCES   (Lithuania)

^b MEDICAL CENTER LEEUWARDEN   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Fluid challenge; Fluid responsiveness; Microcirculation; Organ perfusion; SDF imaging

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD VESSEL PARAMETERS; CLINICAL SIGNS OF IMPAIRED ORGAN PERFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRITICALLY ILL PATIENT; FEMALE; FLUID THERAPY; HEART STROKE VOLUME; HEMODYNAMIC MONITORING; HUMAN; IN VIVO STUDY; INCIDENCE; INTENSIVE CARE UNIT; INVASIVE PROCEDURE; MAJOR CLINICAL STUDY; MALE; MICROCIRCULATION; MICROVASCULAR FLOW INDEX; OBSERVATIONAL STUDY; ORGAN PERFUSION; PATIENT IDENTIFICATION; REFERENCE VALUE; SUBLINGUAL MICROCIRCULATION;

AGED; APACHE; BLOOD FLOW VELOCITY; CRITICAL ILLNESS; FEMALE; FLUID THERAPY; HUMANS; INTENSIVE CARE UNITS; MALE; MICROCIRCULATION; MIDDLE AGED; MOUTH FLOOR; PATIENT SELECTION; PROSPECTIVE STUDIES; TERTIARY CARE CENTERS;

EID: 84884211459     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-012-2793-8     Document Type: Article

References (30)

1. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL (2008) Surviving sepsis campaign: International Guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med 34:17-60. doi: 10.1007/s00134-007-0934-2
2. Vincent JL, Weil MH (2006) Fluid challenge revisited. Crit Care Med 34:1333-1337. doi: 10.1097/01.CCM.0000214677.76535.A5
3. Vincent JL, Rhodes A, Perel A, Martin GS, Della Rocca G, Vallet B, Pinsky MR, Hofer CK, Teboul JL, de Boode WP, Scolletta S, Vieillard-Baron A, De Backer D, Walley KR, Maggiorini M, Singer M (2011) Clinical review: update on hemodynamic monitoring - a consensus of 16. Crit Care 15:229. doi: 10.1186/cc10291
4. Michard F, Teboul JL (2002) Predicting fluid responsiveness in ICU patients: a critical analysis of the evidence. Chest 121:2000-2008
5. Groner W, Winkelman JW, Harris AG, Ince C, Bouma GJ, Messmer K, Nadeau RG (1999) Orthogonal polarization spectral imaging: a new method for study of the microcirculation. Nat Med 5:1209-1212. doi: 10.1038/13529
6. Goedhart PT, Khalilzada M, Bezemer R, Merza J, Ince C (2007) Sidestream dark field (SDF) imaging: a novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation. Opt Express 15:15101-15114
7. Maier S, Holz-Hölzl C, Pajk W, Ulmer H, Hengl C, Dünser M, Haas T, Velik-Salchner C, Fries D, Greiner A, Hasibeder W, Knotzer H (2009) Microcirculatory parameters after isotonic and hypertonic colloidal fluid resuscitation in acute hemorrhagic shock. J Trauma 66:337-345. doi: 10.1097/TA.0b013e31817dac66
8. Dubin A, Pozo MO, Ferrara G, Murias G, Martins E, Canullán C, Canales HS, Kanoore Edul VS, Estenssoro E, Ince C (2009) Systemic and microcirculatory responses to progressive hemorrhage. Intensive Care Med 35:556-564. doi: 10.1007/s00134-008-1385-0
9. Pottecher J, Deruddre S, Teboul JL, Georger JF, Laplace C, Benhamou D, Vicaut E, Duranteau J (2010) Both passive leg raising and intravascular volume expansion improve sublingual microcirculatory perfusion in severe sepsis and septic shock patients. Intensive Care Med 36:1867-1874. doi: 10.1007/s00134-010-1966-6
10. Ospina-Tascon G, Neves AP, Occhipinti G, Donadello K, Büchele G, Simion D, Chierego ML, Silva TO, Fonseca A, Vincent JL, De Backer D (2010) Effects of fluids on microvascular perfusion in patients with severe sepsis. Intensive Care Med 36:949-955
11. Boerma EC, Mathura KR, van der Voort PHJ, Spronk PE, Ince C (2005) Quantifying bedside-derived imaging of microcirculatory abnormalities in septic patients: a prospective validation study. Crit Care 9:R601-R606. doi: 10.1186/cc3809
12. Trzeciak S, Dellinger RP, Parrillo JE, Guglielmi M, Bajaj J, Abate NL, Arnold RC, Colilla S, Zanotti S, Hollenberg SM (2007) Microcirculatory alterations in resuscitation and shock investigators. Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival. Ann Emerg Med 49:88-98. doi: 10.1016/j.annemergmed.2006.08.021 98.e1
13. Dobbe JGG, Streekstra GJ, Atasever B, van Zijderveld R, Ince C (2008) Measurement of functional microcirculatory geometry and velocity distributions using automated image analysis. Med Biol Eng Comput 46:659-670. doi: 10.1007/s11517-008-0349-4
14. De Backer D, Hollenberg S, Boerma C, Goedhart P, Büchele G, Ospina-Tascon G, Dobbe I, Ince C (2007) How to evaluate the microcirculation: report of a round table conference. Crit Care 11:R101. doi: 10.1186/cc6118
15. Zimmerman JE, Kramer AA, McNair DS, Malila FM (2006) Acute physiology and chronic health evaluation (APACHE) IV: hospital mortality assessment for today's critically ill patients. Crit Care Med 34:1297-1310. doi: 10.1097/01.CCM.0000215112.84523.F0
16. Vincent JL, de Mendonça A, Cantraine F, Moreno R, Takala J, Suter PM, Sprung CL, Colardyn F, Blecher S (1998) Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of intensive care medicine. Crit Care Med 26:1793-1800
17. Spanos A, Jhanji S, Vivian-Smith A, Harris T, Pearse RM (2009) Early microvascular changes in sepsis and severe sepsis. Shock. doi: 10.1097/SHK.0b013e3181c6be04
18. Boerma EC, van der Voort PHJ, Spronk PE, Ince C (2007) Relationship between sublingual and intestinal microcirculatory perfusion in patients with abdominal sepsis. Crit Care Med 35:1055-1060. doi: 10.1097/01.CCM.0000259527. 89927.F9
19. Edul VSK, Enrico C, Laviolle B, Vazquez AR, Ince C, Dubin A (2012) Quantitative assessment of the microcirculation in healthy volunteers and in patients with septic shock. Crit Care Med. doi: 10.1097/CCM.0b013e31823dae59
20. Jhanji S, Lee C, Watson D, Hinds C, Pearse RM (2009) Microvascular flow and tissue oxygenation after major abdominal surgery: association with post-operative complications. Intensive Care Med 35:671-677. doi: 10.1007/s00134-008-1325-z
21. Arnold RC, Parrillo JE, Phillip Dellinger R, Chansky ME, Shapiro NI, Lundy DJ, Trzeciak S, Hollenberg SM (2009) Point-of-care assessment of microvascular blood flow in critically ill patients. Intensive Care Med 35:1761-1766. doi: 10.1007/s00134-009-1517-1
22. De Backer D, Creteur J, Dubois MJ, Sakr Y, Vincent JL (2004) Microvascular alterations in patients with acute severe heart failure and cardiogenic shock. Am Heart J 147:91-99
23. Sakr Y, Dubois MJ, De Backer D, Creteur J, Vincent JL (2004) Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med 32:1825-1831
24. Sheikh MY, Javed U, Singh J, Choudhury J, Deen O, Dhah K, Peterson MW (2009) Bedside sublingual video imaging of microcirculation in assessing bacterial infection in cirrhosis. Dig Dis Sci. doi: 10.1007/s10620-008-0664-5
25. Trzeciak S, McCoy JV, Phillip Dellinger R, Arnold RC, Rizzuto M, Abate NL, Shapiro NI, Parrillo JE, Hollenberg SM (2008) Microcirculatory alterations in resuscitation and shock (MARS) investigators Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis. Intensive Care Med 34:2210-2217. doi: 10.1007/s00134-008-1193-6
26. Lansdorp B, Lemson J, van Putten MJAM, de Keijzer A, van der Hoeven JG, Pickkers P (2012) Dynamic indices do not predict volume responsiveness in routine clinical practice. Br J Anaesth 108:395-401. doi: 10.1093/bja/aer411
27. Dubin A, Pozo MO, Casabella CA, Murias G, Pálizas F, Moseinco MC, Kanoore Edul VS, Estenssoro E, Ince C (2010) Comparison of 6 % hydroxyethyl starch 130/0.4 and saline solution for resuscitation of the microcirculation during the early goal-directed therapy of septic patients. J Crit Care 25(4):659.e1-659.e8. doi: 10.1016/j.jcrc.2010.04.007
28. van Haren FMP, Sleigh J, Boerma EC, La Pine M, Bahr M, Pickkers P, van der Hoeven JG (2012) Hypertonic fluid administration in patients with septic shock: a prospective randomized controlled pilot study. Shock 37:268-275. doi: 10.1097/SHK.0b013e31823f152f
29. Pranskunas A, Pilvinis V, Dambrauskas Z, Rasimaviciute R, Planciuniene R, Dobozinskas P, Veikutis V, Vaitkaitis D, Boerma EC (2012) Early course of microcirculatory perfusion in eye and digestive tract during hypodynamic sepsis. Crit Care 16:R83. doi: 10.1186/cc11341
30. Dubin A, Edul VS, Pozo MO, Murias G, Canullán CM, Martins EF, Ferrara G, Canales HS, Laporte M, Estenssoro E, Ince C (2008) Persistent villi hypo-perfusion explains intra-mucosal acidosis in sheep endotoxemia. Crit Care Med 36:535-542. doi: 10.1097/01.CCM.0000300083.74726.43