Anti-adhesive antimicrobial peptide coating prevents catheter associated infection in a mouse urinary infection model

Biomaterials

Volumn 116, Issue , 2017, Pages 69-81

  Yu, Kai ^a   Lo, Joey C Y ^a   Yan, Mei ^a   Yang, Xiaoqiang ^a   Brooks, Donald E ^a   Hancock, Robert E W ^a   Lange, Dirk ^a   Kizhakkedathu, Jayachandran N ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Antimicrobial peptide; Biocompatibility; Catheter associated urinary tract infections; Polymer brush coating; Urinary infection model

Indexed keywords

ADHESION; AMINO ACIDS; ATOMIC FORCE MICROSCOPY; BACTERIA; BIOCOMPATIBILITY; CATHETERS; CELL ADHESION; CELL CULTURE; COATINGS; FUNCTIONAL POLYMERS; MAMMALS; MICROORGANISMS; PEPTIDES; POLYPEPTIDES;

ANTI-MICROBIAL ACTIVITY; ANTIMICROBIAL COATINGS; ANTIMICROBIAL PEPTIDE; ECONOMIC CONSEQUENCES; HOSPITAL ACQUIRED INFECTION; INFECTION MODELS; POLYMER BRUSHES; URINARY TRACT INFECTIONS;

PLASTIC COATINGS;

CATHELICIDIN; CYSTEINE; POLYMER; POLYPEPTIDE ANTIBIOTIC AGENT; POLYURETHAN; POLY[2 (DIMETHYLAMINO)ETHYL METHACRYLATE]; ANTIMICROBIAL CATIONIC PEPTIDE; BIOCOMPATIBLE COATED MATERIAL;

ADHESION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ARTICLE; ATOMIC FORCE MICROSCOPY; BACTERIAL GROWTH; BACTERIUM ADHERENCE; BACTERIUM CULTURE; BIOCOMPATIBILITY; BLADDER EPITHELIUM; CARBOXY TERMINAL SEQUENCE; CATHETER ASSOCIATED URINARY TRACT INFECTION; CATHETER INFECTION; CELL CULTURE; CLINICAL EFFECTIVENESS; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; EPITHELIUM CELL; FIBROBLAST; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MATERIAL COATING; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURFACE PROPERTY; URINALYSIS; URINARY CATHETER; URINARY TRACT INFECTION; ADVERSE DEVICE EFFECT; ANIMAL; C57BL MOUSE; CHEMISTRY; DRUG EFFECTS; MALE; MEDICAL DEVICE CONTAMINATION; MICROBIOLOGY;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL ADHESION; CATHETER-RELATED INFECTIONS; COATED MATERIALS, BIOCOMPATIBLE; EQUIPMENT CONTAMINATION; MALE; MICE; MICE, INBRED C57BL; URINARY CATHETERS; URINARY TRACT INFECTIONS;

EID: 85000916597     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2016.11.047     Document Type: Article

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