Antimicrobial functionalization of silicone surfaces with engineered short peptides having broad spectrum antimicrobial and salt-resistant properties

Acta Biomaterialia

Volumn 10, Issue 1, 2014, Pages 258-266

  Li, Xiang ^a   Li, Peng ^a   Saravanan, Rathi ^b   Basu, Anindya ^a   Mishra, Biswajit ^a   Lim, Suo Hon ^c   Su, Xiaodi ^c   Tambyah, Paul Anantharajah ^d   Leong, Susanna Su Jan ^d,e  

^a Nanyang Technological University   (Singapore)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^c INSTITUTE OF MATERIALS RESEARCH AND ENGINEERING   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e SINGAPORE INSTITUTE OF TECHNOLOGY   (Singapore)

Author keywords

Antimicrobial peptide; Catheter; Infections; Polymer brush; Silicone

Indexed keywords

AMINO ACIDS; ANTIBIOTICS; CATHETERS; CELL ADHESION; HEALTH RISKS; MICROORGANISMS; PATHOGENS; PEPTIDES; PLASTIC COATINGS; X RAY PHOTOELECTRON SPECTROSCOPY;

ALLYL GLYCIDYL ETHERS; ANTIMICROBIAL FUNCTIONALIZATION; ANTIMICROBIAL PEPTIDE; BROAD SPECTRUM; CATHETER SURFACE; INFECTION; POLYMER BRUSHES; PROPERTY; SILICONE SURFACES; URINARY TRACT INFECTIONS;

DENDRIMERS;

ALLYL GLYCIDYL ETHER; ARGININE; DIMETICONE; ETHER; LYSINE; PHOSPHATE BUFFERED SALINE; POLYMER; POLYPEPTIDE ANTIBIOTIC AGENT; SILICONE; SODIUM CHLORIDE; TRYPTOPHAN; UNCLASSIFIED DRUG; WATER;

ANTIMICROBIAL ACTIVITY; ANTIMICROBIAL URINARY CATHETER; ARTICLE; BACTERICIDAL ACTIVITY; BACTERIUM ADHERENCE; BIOCOMPATIBILITY; BIOFILM; CANDIDA ALBICANS; CATHETER ASSOCIATED URINARY TRACT INFECTION; CATHETER INFECTION; CELL ADHESION; CHEMICAL COMPOSITION; CONJUGATION; CONTACT ANGLE; CONTROLLED STUDY; CYTOTOXICITY; DIFFUSION; ESCHERICHIA COLI; FEASIBILITY STUDY; FOLEY BALLOON CATHETER; FUNGICIDAL ACTIVITY; INFECTION PREVENTION; MEMBRANE DAMAGE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN IMMOBILIZATION; SALT TOLERANCE; SMOOTH MUSCLE FIBER; STAPHYLOCOCCUS AUREUS; SURFACE PROPERTY; URINARY TRACT INFECTION; URINE; X RAY PHOTOELECTRON SPECTROSCOPY;

FUNGI;

ANTIMICROBIAL PEPTIDE; CATHETER; INFECTIONS; POLYMER BRUSH; SILICONE;

ADENOSINE TRIPHOSPHATE; ANTI-INFECTIVE AGENTS; BIOFILMS; CANDIDA; CELL ADHESION; DIMETHYLPOLYSILOXANES; ESCHERICHIA COLI; IMMOBILIZED PROTEINS; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; MYOCYTES, SMOOTH MUSCLE; PEPTIDES; PHOTOELECTRON SPECTROSCOPY; PROTEIN ENGINEERING; SILICONES; SODIUM CHLORIDE; SOLUBILITY; STAPHYLOCOCCUS AUREUS; URINARY CATHETERS; WETTABILITY;

EID: 84888638582     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.09.009     Document Type: Article

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