Screening the impact of sirtuin inhibitors on inflammatory and innate immune responses of macrophages and in a mouse model of endotoxic shock

Methods in Molecular Biology

Volumn 1436, Issue , 2016, Pages 313-334

  Ciarlo, Eleonora ^a   Roger, Thierry ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Cytokine; Endotoxemia; Epigenetics; Histone deacetylases; Innate immunity; Macrophage; Pharmacological inhibitors; Sepsis; Sirtuins

Indexed keywords

COMPLEMENTARY DNA; HISTONE DEACETYLASE INHIBITOR; INTERLEUKIN 6; SIRTUIN; TUMOR NECROSIS FACTOR; CYTOKINE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CYTOKINE PRODUCTION; DNA SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAW 264.7 CELL LINE; RNA PURIFICATION; SCREENING; SEPTIC SHOCK; ANIMAL; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; IMMUNOLOGY; METABOLISM; PRECLINICAL STUDY;

ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION REGULATION; HISTONE DEACETYLASE INHIBITORS; IMMUNITY, INNATE; MACROPHAGES; MICE; RAW 264.7 CELLS; SHOCK, SEPTIC; SIRTUINS;

EID: 84999624960     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4939-3667-0_21     Document Type: Article

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