SIRT1 deacetylates RORγt and enhances Th17 cell generation

Journal of Experimental Medicine

Volumn 212, Issue 5, 2015, Pages 607-617

  Lim, Hyung W ^a   Kang, Seung Goo ^c   Ryu, Jae Kyu ^a   Schilling, Birgit ^d   Fei, Mingjian ^a   Lee, Intelly S ^a   Kehasse, Amanuel ^d   Shirakawa, Kotaro ^a   Yokoyama, Masaru ^e   Schnölzer, Martina ^f   Kasler, Herbert G ^a   Kwon, Hye Sook ^a   Gibson, Bradford W ^a,d   Sato, Hironori ^e   Akassoglou, Katerina ^a,b   Xiao, Changchun ^c   Littman, Dan R ^g   Ott, Melanie ^a   Verdin, Eric ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^e NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^f GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^g NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; DNA; INTERLEUKIN 17; INTERLEUKIN 2; RETINOID RELATED ORPHAN RECEPTOR GAMMA; RETINOID RELATED ORPHAN RECEPTOR GAMMA T; SIRTUIN 1; UNCLASSIFIED DRUG; SIRT1 PROTEIN, MOUSE;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL POPULATION; CHIMERA; CONTROLLED STUDY; DEACETYLATION; DNA BINDING; LYMPHOCYTE DIFFERENTIATION; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE SUBPOPULATION; TH17 CELL; THYMOCYTE; ACETYLATION; ANIMAL; CELL DIFFERENTIATION; DISEASE MODEL; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY;

ACETYLATION; ANIMALS; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; MICE; MICE, KNOCKOUT; MULTIPLE SCLEROSIS; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; SIRTUIN 1; TH17 CELLS; TRANSCRIPTION, GENETIC;

EID: 84940110100     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20132378     Document Type: Article

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