Macrophage migration inhibitory factor deficiency is associated with impaired killing of gram-negative bacteria by macrophages and increased susceptibility to Klebsiella pneumoniae sepsis

Journal of Infectious Diseases

Volumn 207, Issue 2, 2013, Pages 331-339

  Roger, Thierry ^a   Delaloye, Julie ^a   Chanson, Anne Laure ^a   Giddey, Marlyse ^b   Le Roy, Didier ^a   Calandra, Thierry ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Bacterial killing; Gram negative Bacteria; Macrophage; Macrophage migration inhibitory factor; Phagocytosis

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MACROPHAGE MIGRATION INHIBITION FACTOR; NITRIC OXIDE; TUMOR NECROSIS FACTOR;

ADAPTIVE IMMUNITY; ARTICLE; BACTERICIDAL ACTIVITY; DEFENSE MECHANISM; DISEASE PREDISPOSITION; ESCHERICHIA COLI; GEL MOBILITY SHIFT ASSAY; GRAM NEGATIVE BACTERIUM; GRAM NEGATIVE SEPSIS; HOST RESISTANCE; INNATE IMMUNITY; KLEBSIELLA PNEUMONIAE; MACROPHAGE MIGRATION INHIBITION; MORTALITY; NONHUMAN; PHAGOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; CELL LINE; CELLS, CULTURED; GRAM-NEGATIVE BACTERIA; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MACROPHAGES; MICE; MICE, INBRED BALB C; PHAGOCYTOSIS;

EID: 84871731343     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jis673     Document Type: Article

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