Adenosine triphosphate analogs can efficiently inhibit the Zika virus RNA-dependent RNA polymerase

Antiviral Research

Volumn 137, Issue , 2017, Pages 131-133

  Hercík, Kamil ^a   Kozak, Jaroslav ^a   Šála, Michal ^a   Dejmek, Milan ^a   Hřebabecký, Hubert ^a   Zborníková, Eva ^a   Smola, Miroslav ^a   Ruzek, Daniel ^b,c   Nencka, Radim ^a   Boura, Evzen ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^b VETERINARY RESEARCH INSTITUTE   (Czech Republic)

^c INSTITUTE OF PARASITOLOGY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE DERIVATIVE; CARBOHYDRATE; RNA DIRECTED RNA POLYMERASE; ADENOSINE TRIPHOSPHATE; ANTIVIRUS AGENT; ENZYME INHIBITOR; NUCLEOSIDE;

ARTICLE; ASSAY; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME PURIFICATION; IC50; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ZIKA VIRUS; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CONFORMATION; DRUG DEVELOPMENT; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HUMAN; ISOLATION AND PURIFICATION;

ADENOSINE TRIPHOSPHATE; ANTIVIRAL AGENTS; DRUG DISCOVERY; ENZYME INHIBITORS; HUMANS; MOLECULAR CONFORMATION; NUCLEOSIDES; RNA REPLICASE; ZIKA VIRUS;

EID: 84999289120     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2016.11.020     Document Type: Article

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