Structure-activity relationships of nucleoside analogues for inhibition of tick-borne encephalitis virus

Antiviral Research

Volumn 133, Issue , 2016, Pages 119-129

  Eyer, Luděk ^a   Šmídková, Markéta ^b   Nencka, Radim ^b   Neča, Jiří ^a   Kastl, Tomáš ^a   Palus, Martin ^a,d   De Clercq, Erik ^c   Růžek, Daniel ^a,d  

^a VETERINARY RESEARCH INSTITUTE   (Czech Republic)

^b INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^d UNIVERSITY OF SOUTH BOHEMIA   (Czech Republic)

Author keywords

Antiviral activity; Cytotoxicity; Nucleoside inhibitor; Structure activity relationship; Tick borne encephalitis

Indexed keywords

2' METHYLADENOSINE; 2' METHYLCYTIDINE; 2' METHYLGUANOSINE; 2' METHYLURIDINE; 2' O METHYLADENOSINE; 2' O METHYLCYTIDINE; 2' O METHYLGUANOSINE; 2' O METHYLURIDINE; 3 DEAZANEPLANOCIN A; 3' DEOXYCYTIDINE; 3' DEOXYGUANOSINE; 3' O METHYLADENOSINE; 3' O METHYLCYTIDINE; 3' O METHYLGUANOSINE; 3' O METHYLURIDINE; 4' AZIDOCYTIDINE; 7 DEAZA 2' METHYLADENOSINE; AZAURIDINE; BALAPIRAVIR; CORDYCEPIN; MERICITABINE; NEPLANOCIN A; NUCLEOSIDE ANALOG; PSI 6206; RIBAVIRIN; RO 9187; SANGIVAMYCIN; SOFOSBUVIR; TOYOCAMYCIN; TUBERCIDIN; UNCLASSIFIED DRUG; ANTIVIRUS AGENT; NUCLEOSIDE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOTOXICITY; EC50; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TICK BORNE ENCEPHALITIS VIRUS; ANIMAL; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; PIG; TICK BORNE ENCEPHALITIS; VIROLOGY; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENCEPHALITIS VIRUSES, TICK-BORNE; ENCEPHALITIS, TICK-BORNE; MOLECULAR STRUCTURE; NUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE; VIRUS REPLICATION;

EID: 84982836748     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2016.07.018     Document Type: Article

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