Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy

Oncotarget

Volumn 7, Issue 48, 2016, Pages 78653-78666

  Crittenden, Marka R ^a,b   Baird, Jason ^a   Friedman, David ^a   Savage, Talicia ^a   Uhde, Lauren ^a   Alice, Alejandro ^a   Cottam, Benjamin ^a   Young, Kristina ^a,b   Newell, Pippa ^a   Nguyen, Cynthia ^a   Bambina, Shelly ^a   Kramer, Gwen ^a   Akporiaye, Emmanuel ^a   Malecka, Anna ^c   Jackson, Andrew ^c   Gough, Michael J ^a  

^a PROVIDENCE PORTLAND MEDICAL CENTER   (United States)

^b Oregon Clinic   (United States)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Apoptosis; Macrophage; Phagocytosis; Radiation; Tumor

Indexed keywords

GAMMA INTERFERON; GROWTH ARREST SPECIFIC PROTEIN 6; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; MERTK PROTEIN; PROTEIN S; PROTEIN TYROSINE KINASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; AZABICYCLO DERIVATIVE; CYTOKINE; HYBRID PROTEIN; MERTK PROTEIN, MOUSE; PROTEIN KINASE MER; SM16 COMPOUND; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER SURVIVAL; COLORECTAL CARCINOMA; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINE RESPONSE; INTRACELLULAR SIGNALING; MACROPHAGE; MOUSE; NONHUMAN; OVERALL SURVIVAL; PREDICTIVE VALUE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIATION FIELD; SURVIVAL ANALYSIS; SURVIVAL PREDICTION; TREATMENT RESPONSE; TUMOR MACROPHAGE; TUMOR RECURRENCE; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; C57BL MOUSE; COCULTURE; DEFICIENCY; ENZYMOLOGY; EXPERIMENTAL NEOPLASM; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; RADIATION RESPONSE; RAW 264.7 CELL LINE; SIGNAL TRANSDUCTION; TIME FACTOR; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; AZABICYCLO COMPOUNDS; C-MER TYROSINE KINASE; CELL LINE, TUMOR; COCULTURE TECHNIQUES; CYTOKINES; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOPLASM RECURRENCE, LOCAL; NEOPLASMS, EXPERIMENTAL; NF-KAPPA B; RAW 264.7 CELLS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84998727461     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.11823     Document Type: Article

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