CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy in prostate cancer

Cancer Research

Volumn 73, Issue 9, 2013, Pages 2782-2794

  Xu, Jingying ^a   Escamilla, Jemima ^a   Mok, Stephen ^a   David, John ^a   Priceman, Saul ^e   West, Brian ^f   Bollag, Gideon ^f   McBride, William ^b   Wu, Lily ^a,c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Departments of Radiation Oncology   (United States)

^c Departments of Urology   (United States)

^d Departments of Pediatrics   (United States)

^e CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^f PLEXXIKON INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1; COLONY STIMULATING FACTOR 1 RECEPTOR; COLONY STIMULATING FACTOR RECEPTOR; PROTEIN ABL1; PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CANCER INFILTRATION; CANCER INHIBITION; CANCER TISSUE; CELL COUNT; CELL NUCLEUS; CONTROLLED STUDY; CSF1 GENE; DNA DAMAGE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG; LYMPH NODE; MACROPHAGE MIGRATION; MALE; MOUSE; MYELOID DERIVED SUPPRESSOR CELL; NONHUMAN; OUTCOME ASSESSMENT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CANCER; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RADIATION RESPONSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPLEEN; SUPPRESSOR CELL; TUMOR ASSOCIATED LEUKOCYTE;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CELL MOVEMENT; CHROMATIN; DNA DAMAGE; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; MYELOID CELLS; NEOPLASM TRANSPLANTATION; PROSTATIC NEOPLASMS; RADIOTHERAPY; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; SIGNAL TRANSDUCTION;

EID: 84877738839     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-3981     Document Type: Article

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