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Volumn 136, Issue 4, 2012, Pages 437-447

Targeting macrophages in the tumour environment to enhance the efficacy of αOX40 therapy

Author keywords

Arginase; Interleukin 12; Interleukin 18; Macrophage; OX40

Indexed keywords

ALPHA OX40 ANTIBODY; ARGINASE; CCL1 CHEMOKINE; CD11B ANTIGEN; CD134 ANTIGEN; CD14 ANTIGEN; CD4 ANTIGEN; CXCL11 CHEMOKINE; CXCL13 CHEMOKINE; CXCL16 CHEMOKINE; CXCL9 CHEMOKINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EOTAXIN 2; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLYCOPROTEIN P 15095; IMMUNOMODULATING AGENT; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 3; NEURONAL NITRIC OXIDE SYNTHASE; RANTES; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84863205440     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2012.03600.x     Document Type: Article
Times cited : (25)

References (51)
  • 1
    • 31544441610 scopus 로고    scopus 로고
    • Distinct role of macrophages in different tumor microenvironments
    • Lewis CE, Pollard JW. Distinct role of macrophages in different tumor microenvironments. Cancer Res 2006; 66:605-12.
    • (2006) Cancer Res , vol.66 , pp. 605-612
    • Lewis, C.E.1    Pollard, J.W.2
  • 3
    • 34248172324 scopus 로고    scopus 로고
    • Altered macrophage differentiation and immune dysfunction in tumor development
    • PMCID: 1857267.
    • Sica A, Bronte V. Altered macrophage differentiation and immune dysfunction in tumor development. J Clin Invest. 2007; 117:1155-66 PMCID: 1857267.
    • (2007) J Clin Invest. , vol.117 , pp. 1155-1166
    • Sica, A.1    Bronte, V.2
  • 4
    • 0028031582 scopus 로고
    • Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2
    • Rosenberg SA, Yannelli JR, Yang JC et al. Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2. J Natl Cancer Inst 1994; 86:1159-66.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1159-1166
    • Rosenberg, S.A.1    Yannelli, J.R.2    Yang, J.C.3
  • 5
    • 0027525986 scopus 로고
    • Adoptive immunotherapy of renal cell carcinoma: studies from the Surgery Branch, National Cancer Institute
    • Linehan WM, Walther MM, Alexander RB, Rosenberg S. Adoptive immunotherapy of renal cell carcinoma: studies from the Surgery Branch, National Cancer Institute. Semin Urol 1993; 11:41-3.
    • (1993) Semin Urol , vol.11 , pp. 41-43
    • Linehan, W.M.1    Walther, M.M.2    Alexander, R.B.3    Rosenberg, S.4
  • 6
    • 17844391297 scopus 로고    scopus 로고
    • Gene therapy to manipulate effector T cell trafficking to tumors for immunotherapy
    • Gough M, Crittenden M, Thanarajasingam U et al. Gene therapy to manipulate effector T cell trafficking to tumors for immunotherapy. J Immunol 2005; 174:5766-73.
    • (2005) J Immunol , vol.174 , pp. 5766-5773
    • Gough, M.1    Crittenden, M.2    Thanarajasingam, U.3
  • 7
    • 31544446571 scopus 로고    scopus 로고
    • + immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • + immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res 2006; 66:1123-31.
    • (2006) Cancer Res , vol.66 , pp. 1123-1131
    • Huang, B.1    Pan, P.Y.2    Li, Q.3
  • 8
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 2004; 10:942-9.
    • (2004) Nat Med , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3
  • 9
    • 38549141719 scopus 로고    scopus 로고
    • IL-10 and the resolution of infections
    • Filippi CM, von Herrath MG. IL-10 and the resolution of infections. J Pathol 2008; 214:224-30.
    • (2008) J Pathol , vol.214 , pp. 224-230
    • Filippi, C.M.1    von Herrath, M.G.2
  • 10
    • 56149103896 scopus 로고    scopus 로고
    • Macrophage polarization in bacterial infections
    • Benoit M, Desnues B, Mege JL. Macrophage polarization in bacterial infections. J Immunol 2008; 181:3733-9.
    • (2008) J Immunol , vol.181 , pp. 3733-3739
    • Benoit, M.1    Desnues, B.2    Mege, J.L.3
  • 11
    • 41149148269 scopus 로고    scopus 로고
    • Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives
    • Rodriguez PC, Ochoa AC. Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives. Immunol Rev 2008; 222:180-91.
    • (2008) Immunol Rev , vol.222 , pp. 180-191
    • Rodriguez, P.C.1    Ochoa, A.C.2
  • 13
    • 38849164304 scopus 로고    scopus 로고
    • Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist
    • Redmond WL, Gough MJ, Charbonneau B, Ratliff TL, Weinberg AD. Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist. J Immunol 2007; 179:7244-53.
    • (2007) J Immunol , vol.179 , pp. 7244-7253
    • Redmond, W.L.1    Gough, M.J.2    Charbonneau, B.3    Ratliff, T.L.4    Weinberg, A.D.5
  • 15
    • 0032534582 scopus 로고    scopus 로고
    • Ox-40 ligand: a potent costimulatory molecule for sustaining primary CD4 T cell responses
    • Gramaglia I, Weinberg AD, Lemon M, Croft M. Ox-40 ligand: a potent costimulatory molecule for sustaining primary CD4 T cell responses. J Immunol 1998; 161:6510-7.
    • (1998) J Immunol , vol.161 , pp. 6510-6517
    • Gramaglia, I.1    Weinberg, A.D.2    Lemon, M.3    Croft, M.4
  • 16
    • 24744454592 scopus 로고    scopus 로고
    • OX40 and Bcl-xL promote the persistence of CD8 T cells to recall tumor-associated antigen
    • Song A, Tang X, Harms KM, Croft M. OX40 and Bcl-xL promote the persistence of CD8 T cells to recall tumor-associated antigen. J Immunol 2005; 175:3534-41.
    • (2005) J Immunol , vol.175 , pp. 3534-3541
    • Song, A.1    Tang, X.2    Harms, K.M.3    Croft, M.4
  • 17
    • 0037354745 scopus 로고    scopus 로고
    • Expression of CD134 and CD134 ligand in lesional and nonlesional psoriatic skin
    • Matsumura Y, Hori T, Nishigori C et al. Expression of CD134 and CD134 ligand in lesional and nonlesional psoriatic skin. Arch Dermatol Res 2003; 294:563-6.
    • (2003) Arch Dermatol Res , vol.294 , pp. 563-566
    • Matsumura, Y.1    Hori, T.2    Nishigori, C.3
  • 18
    • 0033785481 scopus 로고    scopus 로고
    • Contribution of OX40/OX40 ligand interaction to the pathogenesis of rheumatoid arthritis
    • Yoshioka T, Nakajima A, Akiba H et al. Contribution of OX40/OX40 ligand interaction to the pathogenesis of rheumatoid arthritis. Eur J Immunol 2000; 30:2815-23.
    • (2000) Eur J Immunol , vol.30 , pp. 2815-2823
    • Yoshioka, T.1    Nakajima, A.2    Akiba, H.3
  • 19
    • 0033083303 scopus 로고    scopus 로고
    • Blocking OX-40/OX-40 ligand interaction in vitro and in vivo leads to decreased T cell function and amelioration of experimental allergic encephalomyelitis
    • Weinberg AD, Wegmann KW, Funatake C, Whitham RH. Blocking OX-40/OX-40 ligand interaction in vitro and in vivo leads to decreased T cell function and amelioration of experimental allergic encephalomyelitis. J Immunol 1999; 162:1818-26.
    • (1999) J Immunol , vol.162 , pp. 1818-1826
    • Weinberg, A.D.1    Wegmann, K.W.2    Funatake, C.3    Whitham, R.H.4
  • 20
    • 0034651736 scopus 로고    scopus 로고
    • Engagement of the OX-40 receptor in vivo enhances antitumor immunity
    • Weinberg AD, Rivera MM, Prell R et al. Engagement of the OX-40 receptor in vivo enhances antitumor immunity. J Immunol 2000; 164:2160-9.
    • (2000) J Immunol , vol.164 , pp. 2160-2169
    • Weinberg, A.D.1    Rivera, M.M.2    Prell, R.3
  • 21
    • 48549099849 scopus 로고    scopus 로고
    • OX40 agonist therapy enhances CD8 infiltration and decreases immune suppression in the tumor
    • Gough MJ, Ruby CE, Redmond WL, Dhungel B, Brown A, Weinberg AD. OX40 agonist therapy enhances CD8 infiltration and decreases immune suppression in the tumor. Cancer Res 2008; 68:5206-15.
    • (2008) Cancer Res , vol.68 , pp. 5206-5215
    • Gough, M.J.1    Ruby, C.E.2    Redmond, W.L.3    Dhungel, B.4    Brown, A.5    Weinberg, A.D.6
  • 23
    • 0030853610 scopus 로고    scopus 로고
    • Enhanced induction of antitumor T-cell responses by cytotoxic T lymphocyte-associated molecule-4 blockade: the effect is manifested only at the restricted tumor-bearing stages
    • Yang YF, Zou JP, Mu J et al. Enhanced induction of antitumor T-cell responses by cytotoxic T lymphocyte-associated molecule-4 blockade: the effect is manifested only at the restricted tumor-bearing stages. Cancer Res 1997; 57:4036-41.
    • (1997) Cancer Res , vol.57 , pp. 4036-4041
    • Yang, Y.F.1    Zou, J.P.2    Mu, J.3
  • 24
    • 65249117082 scopus 로고    scopus 로고
    • Thymic OX40 expression discriminates cells undergoing strong responses to selection ligands
    • Klinger M, Kim JK, Chmura SA, Barczak A, Erle DJ, Killeen N. Thymic OX40 expression discriminates cells undergoing strong responses to selection ligands. J Immunol 2009; 182:4581-9.
    • (2009) J Immunol , vol.182 , pp. 4581-4589
    • Klinger, M.1    Kim, J.K.2    Chmura, S.A.3    Barczak, A.4    Erle, D.J.5    Killeen, N.6
  • 25
    • 68949105350 scopus 로고    scopus 로고
    • Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking
    • PMCID: 2719063.
    • Kim JK, Klinger M, Benjamin J et al. Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking. PLoS ONE 2009; 4:e6580 PMCID: 2719063.
    • (2009) PLoS ONE , vol.4
    • Kim, J.K.1    Klinger, M.2    Benjamin, J.3
  • 26
  • 27
    • 33846434093 scopus 로고    scopus 로고
    • The terminology issue for myeloid-derived suppressor cells
    • author reply 6. PMCID: 1941787.
    • Gabrilovich DI, Bronte V, Chen SH et al. The terminology issue for myeloid-derived suppressor cells. Cancer Res 2007; 67:425 author reply 6. PMCID: 1941787.
    • (2007) Cancer Res , vol.67 , pp. 425
    • Gabrilovich, D.I.1    Bronte, V.2    Chen, S.H.3
  • 29
    • 78549292810 scopus 로고    scopus 로고
    • A therapeutic OX40 agonist dynamically alters dendritic, endothelial, and T cell subsets within the established tumor microenvironment
    • Pardee AD, McCurry D, Alber S, Hu P, Epstein AL, Storkus WJ. A therapeutic OX40 agonist dynamically alters dendritic, endothelial, and T cell subsets within the established tumor microenvironment. Cancer Res 2010; 70:9041-52.
    • (2010) Cancer Res , vol.70 , pp. 9041-9052
    • Pardee, A.D.1    McCurry, D.2    Alber, S.3    Hu, P.4    Epstein, A.L.5    Storkus, W.J.6
  • 30
    • 1542514775 scopus 로고    scopus 로고
    • Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells
    • Takeda I, Ine S, Killeen N et al. Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells. J Immunol 2004; 172:3580-9.
    • (2004) J Immunol , vol.172 , pp. 3580-3589
    • Takeda, I.1    Ine, S.2    Killeen, N.3
  • 31
    • 33846823024 scopus 로고    scopus 로고
    • Resolution of inflammation: state of the art, definitions and terms
    • Serhan CN, Brain SD, Buckley CD et al. Resolution of inflammation: state of the art, definitions and terms. FASEB J 2007; 21:325-32.
    • (2007) FASEB J , vol.21 , pp. 325-332
    • Serhan, C.N.1    Brain, S.D.2    Buckley, C.D.3
  • 32
    • 30044449982 scopus 로고    scopus 로고
    • Resolution of inflammation: the beginning programs the end
    • Serhan CN, Savill J. Resolution of inflammation: the beginning programs the end. Nat Immunol 2005; 6:1191-7.
    • (2005) Nat Immunol , vol.6 , pp. 1191-1197
    • Serhan, C.N.1    Savill, J.2
  • 34
    • 0036779617 scopus 로고    scopus 로고
    • Anti-inflammatory lipid mediators and insights into the resolution of inflammation
    • Lawrence T, Willoughby DA, Gilroy DW. Anti-inflammatory lipid mediators and insights into the resolution of inflammation. Nat Rev Immunol 2002; 2:787-95.
    • (2002) Nat Rev Immunol , vol.2 , pp. 787-795
    • Lawrence, T.1    Willoughby, D.A.2    Gilroy, D.W.3
  • 35
    • 0037460123 scopus 로고    scopus 로고
    • Macrophages in chronic type 2 inflammation have a novel phenotype characterized by the abundant expression of Ym1 and Fizz1 that can be partly replicated in vitro
    • Nair MG, Cochrane DW, Allen JE. Macrophages in chronic type 2 inflammation have a novel phenotype characterized by the abundant expression of Ym1 and Fizz1 that can be partly replicated in vitro. Immunol Lett 2003; 85:173-80.
    • (2003) Immunol Lett , vol.85 , pp. 173-180
    • Nair, M.G.1    Cochrane, D.W.2    Allen, J.E.3
  • 36
    • 0037884830 scopus 로고    scopus 로고
    • Nitric oxide-independent CTL suppression during tumor progression: association with arginase-producing (M2) myeloid cells
    • Liu Y, Van Ginderachter JA, Brys L, De Baetselier P, Raes G, Geldhof AB. Nitric oxide-independent CTL suppression during tumor progression: association with arginase-producing (M2) myeloid cells. J Immunol 2003; 170:5064-74.
    • (2003) J Immunol , vol.170 , pp. 5064-5074
    • Liu, Y.1    Van Ginderachter, J.A.2    Brys, L.3    De Baetselier, P.4    Raes, G.5    Geldhof, A.B.6
  • 37
    • 4143130091 scopus 로고    scopus 로고
    • Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses
    • Rodriguez PC, Quiceno DG, Zabaleta J et al. Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses. Cancer Res 2004; 64:5839-49.
    • (2004) Cancer Res , vol.64 , pp. 5839-5849
    • Rodriguez, P.C.1    Quiceno, D.G.2    Zabaleta, J.3
  • 38
    • 0041845173 scopus 로고    scopus 로고
    • l-Arginine consumption by macrophages modulates the expression of CD3 zeta chain in T lymphocytes
    • Rodriguez PC, Zea AH, DeSalvo J et al. l-Arginine consumption by macrophages modulates the expression of CD3 zeta chain in T lymphocytes. J Immunol 2003; 171:1232-9.
    • (2003) J Immunol , vol.171 , pp. 1232-1239
    • Rodriguez, P.C.1    Zea, A.H.2    DeSalvo, J.3
  • 40
    • 33847068762 scopus 로고    scopus 로고
    • Mechanism of third signals provided by IL-12 and OX-40R ligation in eliciting therapeutic immunity following dendritic-tumor fusion vaccination
    • Kuriyama H, Watanabe S, Kjaergaard et al. Mechanism of third signals provided by IL-12 and OX-40R ligation in eliciting therapeutic immunity following dendritic-tumor fusion vaccination. Cell Immunol 2006; 243:30-40.
    • (2006) Cell Immunol , vol.243 , pp. 30-40
    • Kuriyama, H.1    Watanabe, S.2    Kjaergaard3
  • 41
    • 33745304780 scopus 로고    scopus 로고
    • IL-18 bridges innate and adaptive immunity through IFN-γ and the CD134 pathway
    • Maxwell JR, Yadav R, Rossi RJ et al. IL-18 bridges innate and adaptive immunity through IFN-γ and the CD134 pathway. J Immunol 2006; 177:234-45.
    • (2006) J Immunol , vol.177 , pp. 234-245
    • Maxwell, J.R.1    Yadav, R.2    Rossi, R.J.3
  • 42
    • 0034663047 scopus 로고    scopus 로고
    • Coadministration of interleukin-18 and interleukin-12 induces a fatal inflammatory response in mice: critical role of natural killer cell interferon-γ production and STAT-mediated signal transduction
    • Carson WE, Dierksheide JE, Jabbour S et al. Coadministration of interleukin-18 and interleukin-12 induces a fatal inflammatory response in mice: critical role of natural killer cell interferon-γ production and STAT-mediated signal transduction. Blood 2000; 96:1465-73.
    • (2000) Blood , vol.96 , pp. 1465-1473
    • Carson, W.E.1    Dierksheide, J.E.2    Jabbour, S.3
  • 43
    • 59449109861 scopus 로고    scopus 로고
    • Secretion of interferon-γ by human macrophages demonstrated at the single-cell level after costimulation with interleukin (IL)-12 plus IL-18
    • PMCID: 2669819.
    • Darwich L, Coma G, Pena R et al. Secretion of interferon-γ by human macrophages demonstrated at the single-cell level after costimulation with interleukin (IL)-12 plus IL-18. Immunology 2009; 126:386-93 PMCID: 2669819.
    • (2009) Immunology , vol.126 , pp. 386-393
    • Darwich, L.1    Coma, G.2    Pena, R.3
  • 44
    • 0021275482 scopus 로고
    • Generation and decay of the immune response to a progressive fibrosarcoma II. Failure to demonstrate postexcision immunity after the onset of T cell-mediated suppression of immunity
    • Bursuker I, North RJ. Generation and decay of the immune response to a progressive fibrosarcoma II. Failure to demonstrate postexcision immunity after the onset of T cell-mediated suppression of immunity. J Exp Med 1984; 159:1312-21.
    • (1984) J Exp Med , vol.159 , pp. 1312-1321
    • Bursuker, I.1    North, R.J.2
  • 46
    • 41849103115 scopus 로고    scopus 로고
    • IFN-γ- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers
    • Zhang B, Karrison T, Rowley DA, Schreiber H. IFN-γ- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers. J Clin Invest 2008; 118:1398-404.
    • (2008) J Clin Invest , vol.118 , pp. 1398-1404
    • Zhang, B.1    Karrison, T.2    Rowley, D.A.3    Schreiber, H.4
  • 47
    • 0016237535 scopus 로고
    • Tumor cytotoxicity in vitro by macrophages from mice infected with Mycobacterium bovis strain BCG
    • Cleveland RP, Meltzer MS, Zbar B. Tumor cytotoxicity in vitro by macrophages from mice infected with Mycobacterium bovis strain BCG. J Natl Cancer Inst 1974; 52:1887-95.
    • (1974) J Natl Cancer Inst , vol.52 , pp. 1887-1895
    • Cleveland, R.P.1    Meltzer, M.S.2    Zbar, B.3
  • 48
    • 78650648668 scopus 로고    scopus 로고
    • CTL induction of tumoricidal nitric oxide production by intratumoral macrophages is critical for tumor elimination
    • Vicetti Miguel RD, Cherpes TL, Watson LJ, McKenna KC. CTL induction of tumoricidal nitric oxide production by intratumoral macrophages is critical for tumor elimination. J Immunol 2010; 185:6706-18.
    • (2010) J Immunol , vol.185 , pp. 6706-6718
    • Vicetti Miguel, R.D.1    Cherpes, T.L.2    Watson, L.J.3    McKenna, K.C.4
  • 49
    • 0032526840 scopus 로고    scopus 로고
    • Murine macrophages secrete interferon γ upon combined stimulation with interleukin (IL)-12 and IL-18: a novel pathway of autocrine macrophage activation
    • Munder M, Mallo M, Eichmann K, Modolell M. Murine macrophages secrete interferon γ upon combined stimulation with interleukin (IL)-12 and IL-18: a novel pathway of autocrine macrophage activation. J Exp Med 1998; 187:2103-8.
    • (1998) J Exp Med , vol.187 , pp. 2103-2108
    • Munder, M.1    Mallo, M.2    Eichmann, K.3    Modolell, M.4
  • 50
    • 42149095015 scopus 로고    scopus 로고
    • IL-12 is required for anti-OX40-mediated CD4 T cell survival
    • Ruby CE, Montler R, Zheng R, Shu S, Weinberg AD. IL-12 is required for anti-OX40-mediated CD4 T cell survival. J Immunol 2008; 180:2140-8.
    • (2008) J Immunol , vol.180 , pp. 2140-2148
    • Ruby, C.E.1    Montler, R.2    Zheng, R.3    Shu, S.4    Weinberg, A.D.5
  • 51
    • 0032522801 scopus 로고    scopus 로고
    • - T cell subsets to express IL-18 receptor and produce IFN-γ in response to IL-18
    • - T cell subsets to express IL-18 receptor and produce IFN-γ in response to IL-18. J Immunol 1998; 160:3759-65.
    • (1998) J Immunol , vol.160 , pp. 3759-3765
    • Tomura, M.1    Maruo, S.2    Mu, J.3


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