-
1
-
-
85049491557
-
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013: A systematic analysis for the Global Burden of Disease Study 2013
-
GBD 2013 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2015;386:2287–323.
-
(2015)
Lancet
, vol.386
, pp. 2287-2323
-
-
-
3
-
-
34548307195
-
Alcohol and cardiovascular health: The razor-sharp double-edged sword
-
O’Keefe JH, Bybee KA, Lavie CJ. Alcohol and cardiovascular health: the razor-sharp double-edged sword. J Am Coll Cardiol 2007;50:1009–14.
-
(2007)
J Am Coll Cardiol
, vol.50
, pp. 1009-1014
-
-
O’Keefe, J.H.1
Bybee, K.A.2
Lavie, C.J.3
-
4
-
-
84892447326
-
The association of pattern of lifetime alcohol use and cause of death in the European Prospective Investigation into Cancer and Nutrition (EPIC) study
-
Bergmann MM, Rehm J, Klipstein-Grobusch K et al. The association of pattern of lifetime alcohol use and cause of death in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Int J Epidemiol 2014;42:1772–90.
-
(2014)
Int J Epidemiol
, vol.42
, pp. 1772-1790
-
-
Bergmann, M.M.1
Rehm, J.2
Klipstein-Grobusch, K.3
-
5
-
-
84904064886
-
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data
-
Holmes MV, Dale CE, Zuccolo L et al. Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ 2014;349:g4164.
-
(2014)
BMJ
, vol.349
, pp. g4164
-
-
Holmes, M.V.1
Dale, C.E.2
Zuccolo, L.3
-
6
-
-
84945191051
-
Effects of initiating moderate alcohol intake on cardiometabolic risk in adults with type 2 diabetes
-
Gepner Y, Golan R, Harman-Boehm I et al. Effects of initiating moderate alcohol intake on cardiometabolic risk in adults with type 2 diabetes. Ann Intern Med 2015;163:569–79.
-
(2015)
Ann Intern Med
, vol.163
, pp. 569-579
-
-
Gepner, Y.1
Golan, R.2
Harman-Boehm, I.3
-
7
-
-
79952066428
-
Effect of alcohol consumption on biological markers associated with risk of coronary heart disease: Systematic review and meta-analysis of interventional studies
-
Brien SE, Ronksley PE, Turner BJ, Mukamal KJ, Ghali WA. Effect of alcohol consumption on biological markers associated with risk of coronary heart disease: systematic review and meta-analysis of interventional studies. BMJ 2011;342:d636.
-
(2011)
BMJ
, vol.342
, pp. d636
-
-
Brien, S.E.1
Ronksley, P.E.2
Turner, B.J.3
Mukamal, K.J.4
Ghali, W.A.5
-
8
-
-
84941584522
-
Exploring causal associations of alcohol with cardiovascular and metabolic risk factors in a Chinese population using Mendelian randomization analysis
-
Taylor AE, Lu F, Carslake D et al. Exploring causal associations of alcohol with cardiovascular and metabolic risk factors in a Chinese population using Mendelian randomization analysis. Sci Rep 2015;5:14005.
-
(2015)
Sci Rep
, vol.5
, pp. 14005
-
-
Taylor, A.E.1
Lu, F.2
Carslake, D.3
-
9
-
-
84951304932
-
Alcohol intake and cardiovascular risk factors: A Mendelian randomisation study
-
Cho Y, Shin S-Y, Won S, Relton CL, Davey Smith G, Shin M-J. Alcohol intake and cardiovascular risk factors: A Mendelian randomisation study. Sci Rep 2015;5:18422.
-
(2015)
Sci Rep
, vol.5
, pp. 18422
-
-
Cho, Y.1
Shin, S.-Y.2
Won, S.3
Relton, C.L.4
Davey Smith, G.5
Shin, M.-J.6
-
10
-
-
84870045994
-
Effects of dalcetrapib in patients with a recent acute coronary syndrome
-
Schwartz GG, Olsson AG, Abt M et al. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med 2012;367:2089–99.
-
(2012)
N Engl J Med
, vol.367
, pp. 2089-2099
-
-
Schwartz, G.G.1
Olsson, A.G.2
Abt, M.3
-
11
-
-
84864845456
-
Plasma HDL cholesterol and risk of myocardial infarction: A mendelian randomisation study
-
Voight BF, Peloso GM, Orho-Melander M et al. Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet 2012;380:572–80.
-
(2012)
Lancet
, vol.380
, pp. 572-580
-
-
Voight, B.F.1
Peloso, G.M.2
Orho-Melander, M.3
-
12
-
-
84884250513
-
Multiethnic meta-analysis of genome-wide association studies in > 100 000 subjects identifies 23 fibrinogen-associated loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease
-
Sabater-Lleal M, Huang J, Chasman D et al. Multiethnic meta-analysis of genome-wide association studies in > 100 000 subjects identifies 23 fibrinogen-associated loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation 2013;128:1310–24.
-
(2013)
Circulation
, vol.128
, pp. 1310-1324
-
-
Sabater-Lleal, M.1
Huang, J.2
Chasman, D.3
-
13
-
-
84891540644
-
Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes
-
Yaghootkar H, Lamina C, Scott R et al. Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes 2013;62:3589–98.
-
(2013)
Diabetes
, vol.62
, pp. 3589-3598
-
-
Yaghootkar, H.1
Lamina, C.2
Scott, R.3
-
14
-
-
84901670702
-
Metabolomic patterns and alcohol consumption in African Americans in the Atherosclerosis Risk in Communities Study
-
Zheng Y, Yu B, Alexander D, Steffen LM, Nettleton JA, Boerwinkle E. Metabolomic patterns and alcohol consumption in African Americans in the Atherosclerosis Risk in Communities Study. Am J Clin Nutr 2014;99:1470–78.
-
(2014)
Am J Clin Nutr
, vol.99
, pp. 1470-1478
-
-
Zheng, Y.1
Yu, B.2
Alexander, D.3
Steffen, L.M.4
Nettleton, J.A.5
Boerwinkle, E.6
-
15
-
-
84880113662
-
Alcohol-induced metabolomic differences in humans
-
Jaremek M, Yu Z, Mangino M et al. Alcohol-induced metabolomic differences in humans. Transl Psychiatry 2013;3:e276.
-
(2013)
Transl Psychiatry
, vol.3
, pp. e276
-
-
Jaremek, M.1
Yu, Z.2
Mangino, M.3
-
16
-
-
84952870164
-
Metabolomic profiling reveals novel biomarkers of alcohol intake and alcohol-induced liver injury in community-dwelling men
-
Harada S, Takebayashi T, Kurihara A et al. Metabolomic profiling reveals novel biomarkers of alcohol intake and alcohol-induced liver injury in community-dwelling men. Environ Health Prev Med 2016;21:18–26.
-
(2016)
Environ Health Prev Med
, vol.21
, pp. 18-26
-
-
Harada, S.1
Takebayashi, T.2
Kurihara, A.3
-
17
-
-
34447127551
-
Alcohol consumption and lipoprotein subclasses in older adults
-
Mukamal KJ, Mackey RH, Kuller LH et al. Alcohol consumption and lipoprotein subclasses in older adults. J Clin Endocrinol Metab 2007;92:2559–66.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 2559-2566
-
-
Mukamal, K.J.1
Mackey, R.H.2
Kuller, L.H.3
-
18
-
-
84929429714
-
Metabolite profiling and cardiovascular event risk: A prospective study of 3 population-based cohorts
-
Würtz P, Havulinna AS, Soininen P et al. Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts. Circulation 2015;131:774–85.
-
(2015)
Circulation
, vol.131
, pp. 774-785
-
-
Würtz, P.1
Havulinna, A.S.2
Soininen, P.3
-
19
-
-
84895429352
-
Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: An observational study of 17,345 persons
-
Fischer K, Kettunen J, Würtz P et al. Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: An observational study of 17,345 persons. PLoS Med 2014;11:e1001606.
-
(2014)
PLoS Med
, vol.11
-
-
Fischer, K.1
Kettunen, J.2
Würtz, P.3
-
20
-
-
84891451520
-
Glycerol and fatty acids in serum predict the development of hyperglycemia and type 2 diabetes in Finnish men
-
Mahendran Y, Cederberg H, Vangipurapu J et al. Glycerol and fatty acids in serum predict the development of hyperglycemia and type 2 diabetes in Finnish men. Diabetes Care 2013;36:3732–38.
-
(2013)
Diabetes Care
, vol.36
, pp. 3732-3738
-
-
Mahendran, Y.1
Cederberg, H.2
Vangipurapu, J.3
-
21
-
-
84863205594
-
Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men
-
Stancakova A, Civelek M, Saleem NK et al. Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men. Diabetes 2012;61:1895–902.
-
(2012)
Diabetes
, vol.61
, pp. 1895-1902
-
-
Stancakova, A.1
Civelek, M.2
Saleem, N.K.3
-
22
-
-
84864384899
-
High-throughput quantification of circulating metabolites improves prediction of sub-clinical atherosclerosis
-
Würtz P, Raiko JR, Magnussen CG et al. High-throughput quantification of circulating metabolites improves prediction of sub-clinical atherosclerosis. Eur Heart J 2012;33:2307–16.
-
(2012)
Eur Heart J
, vol.33
, pp. 2307-2316
-
-
Würtz, P.1
Raiko, J.R.2
Magnussen, C.G.3
-
23
-
-
9644257052
-
Early life factors and blood pressure at age 31 years in the 1966 northern Finland birth cohort
-
J€arvelin M-R, Sovio U, King V et al. Early life factors and blood pressure at age 31 years in the 1966 northern Finland birth cohort. Hypertension 2004;44:838–46.
-
(2004)
Hypertension
, vol.44
, pp. 838-846
-
-
Jarvelin, M.-R.1
Sovio, U.2
King, V.3
-
24
-
-
84920973132
-
Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change
-
Würtz P, Wang Q, Kangas AJ et al. Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change. PLoS Med 2014;11:e1001765.
-
(2014)
PLoS Med
, vol.11
-
-
Würtz, P.1
Wang, Q.2
Kangas, A.J.3
-
25
-
-
77952721703
-
Thirty-five-year trends in cardiovascular risk factors in Finland
-
Vartiainen E, Laatikainen T, Peltonen M et al. Thirty-five-year trends in cardiovascular risk factors in Finland. Int J Epidemiol 2010;39:504–18.
-
(2010)
Int J Epidemiol
, vol.39
, pp. 504-518
-
-
Vartiainen, E.1
Laatikainen, T.2
Peltonen, M.3
-
26
-
-
67349272290
-
Alcohol consumption is directly associated with carotid intima–media thickness in Finnish young adults
-
Juonala M, Viikari JSA, K€ahönen M et al. Alcohol consumption is directly associated with carotid intima–media thickness in Finnish young adults. Atherosclerosis 2009;204:e93–e98.
-
(2009)
Atherosclerosis
, vol.204
, pp. e93-e98
-
-
Juonala, M.1
Viikari, J.S.A.2
Kahönen, M.3
-
27
-
-
0031459035
-
Determinants of gamma-glutamyltransferase: Positive interaction with alcohol and body mass index, negative association with coffee
-
Poikolainen K, Vartiainen E. Determinants of gamma-glutamyltransferase: positive interaction with alcohol and body mass index, negative association with coffee. Am J Epidemiol 1997;146:1019–24.
-
(1997)
Am J Epidemiol
, vol.146
, pp. 1019-1024
-
-
Poikolainen, K.1
Vartiainen, E.2
-
28
-
-
84924533418
-
Quantitative serum nuclear magnetic resonance metabolomics in cardiovascular epidemiology and genetics
-
Soininen P, Kangas AJ, Würtz P, Suna T, Ala-Korpela M. Quantitative serum nuclear magnetic resonance metabolomics in cardiovascular epidemiology and genetics. Circ Cardiovasc Genet 2015;8:192–206.
-
(2015)
Circ Cardiovasc Genet
, vol.8
, pp. 192-206
-
-
Soininen, P.1
Kangas, A.J.2
Würtz, P.3
Suna, T.4
Ala-Korpela, M.5
-
29
-
-
84872685787
-
Long-term leisure-time physical activity and serum metabolome
-
Kujala UM, M€akinen V-P, Heinonen I et al. Long-term leisure-time physical activity and serum metabolome. Circulation 2013;127:340–48.
-
(2013)
Circulation
, vol.127
, pp. 340-348
-
-
Kujala, U.M.1
Makinen, V.-P.2
Heinonen, I.3
-
30
-
-
70349324702
-
High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism
-
Soininen P, Kangas AJ, Würtz P et al. High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism. Analyst 2009;134:1781.
-
(2009)
Analyst
, vol.134
, pp. 1781
-
-
Soininen, P.1
Kangas, A.J.2
Würtz, P.3
-
31
-
-
84962271039
-
Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
-
Kettunen J, Demirkan A, Würtz P et al. Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA. Nat Commun 2016;7:11122.
-
(2016)
Nat Commun
, vol.7
, pp. 11122
-
-
Kettunen, J.1
Demirkan, A.2
Würtz, P.3
-
32
-
-
84861234604
-
Effects of ethanol intake on lipoproteins
-
Brinton EA. Effects of ethanol intake on lipoproteins. Curr Atheroscler Rep 24;4:108–14.
-
Curr Atheroscler Rep
, vol.24
, Issue.4
, pp. 108-114
-
-
Brinton, E.A.1
-
33
-
-
61849110301
-
Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women
-
Mora S, Otvos JD, Rifai N, Rosenson RS, Buring JE, Ridker PM. Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women. Circulation 2009;119:931–39.
-
(2009)
Circulation
, vol.119
, pp. 931-939
-
-
Mora, S.1
Otvos, J.D.2
Rifai, N.3
Rosenson, R.S.4
Buring, J.E.5
Ridker, P.M.6
-
34
-
-
84887058576
-
Common variants associated with plasma triglycerides and risk for coronary artery disease
-
Do R, Willer CJ, Schmidt EM et al. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013;45:1345–52.
-
(2013)
Nat Genet
, vol.45
, pp. 1345-1352
-
-
Do, R.1
Willer, C.J.2
Schmidt, E.M.3
-
35
-
-
84875672652
-
Metabolic and biochemical effects of low-to-moderate alcohol consumption
-
Whitfield JB, Heath AC, Madden PAF, Pergadia ML, Montgomery GW, Martin NG. Metabolic and biochemical effects of low-to-moderate alcohol consumption. Alcoholism Clin Exp Res 2013;37:575–86.
-
(2013)
Alcoholism Clin Exp Res
, vol.37
, pp. 575-586
-
-
Whitfield, J.B.1
Heath, A.C.2
Madden, P.A.F.3
Pergadia, M.L.4
Montgomery, G.W.5
Martin, N.G.6
-
36
-
-
77949906149
-
Alcohol intake, myocardial infarction, biochemical risk factors, and alcohol de-hydrogenase genotypes
-
Tolstrup JS, Gronbaek M, Nordestgaard BG. Alcohol intake, myocardial infarction, biochemical risk factors, and alcohol de-hydrogenase genotypes. Circ Cardiovasc Genet 2009;2:507–14.
-
(2009)
Circ Cardiovasc Genet
, vol.2
, pp. 507-514
-
-
Tolstrup, J.S.1
Gronbaek, M.2
Nordestgaard, B.G.3
-
37
-
-
84927693238
-
Circulating omega-6 polyunsaturated fatty acids and total and cause-specific mortality: The Cardiovascular Health Study
-
Wu JHY, Lemaitre RN, King IB et al. Circulating omega-6 polyunsaturated fatty acids and total and cause-specific mortality: the Cardiovascular Health Study. Circulation 2014;130:1245–53.
-
(2014)
Circulation
, vol.130
, pp. 1245-1253
-
-
Wu, J.H.Y.1
Lemaitre, R.N.2
King, I.B.3
-
39
-
-
84906317616
-
Elevated oleic acid serum concentrations in patients suffering from alcohol dependence
-
Teubert A, Thome J, Büttner A, Richter J, Irmisch G. Elevated oleic acid serum concentrations in patients suffering from alcohol dependence. J Mol Psychiatry 2013;1:13.
-
(2013)
J Mol Psychiatry
, vol.1
, pp. 13
-
-
Teubert, A.1
Thome, J.2
Büttner, A.3
Richter, J.4
Irmisch, G.5
-
40
-
-
84860756406
-
Metabolite profiling identifies pathways associated with metabolic risk in humans
-
Cheng S, Rhee EP, Larson MG, et al. Metabolite profiling identifies pathways associated with metabolic risk in humans. Circulation 2012;125:2222–2231.
-
(2012)
Circulation
, vol.125
, pp. 2222-2231
-
-
Cheng, S.1
Rhee, E.P.2
Larson, M.G.3
-
41
-
-
84879882627
-
Toward new biomarkers of cardiometabolic diseases
-
Roberts LD, Gerszten RE. Toward new biomarkers of cardiometabolic diseases. Cell Metab 2013;18:43–50.
-
(2013)
Cell Metab
, vol.18
, pp. 43-50
-
-
Roberts, L.D.1
Gerszten, R.E.2
-
42
-
-
83755178091
-
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of a-ketoglutarate to citrate to support cell growth and viability
-
Wise DR, Ward PS, Shay JES et al. Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of a-ketoglutarate to citrate to support cell growth and viability. Proc Natl Acad Sci U S A 2011;108:19611–16.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 19611-19616
-
-
Wise, D.R.1
Ward, P.S.2
Shay, J.E.S.3
-
43
-
-
84883497454
-
Glutamine and cancer: Cell biology, physiology, and clinical opportunities
-
Hensley CT, Wasti AT, DeBerardinis RJ. Glutamine and cancer: cell biology, physiology, and clinical opportunities. J Clin Invest 2013;123:3678–3684.
-
(2013)
J Clin Invest
, vol.123
, pp. 3678-3684
-
-
Hensley, C.T.1
Wasti, A.T.2
DeBerardinis, R.J.3
|