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Volumn 3, Issue , 2013, Pages

Alcohol-induced metabolomic differences in humans

Author keywords

alcohol; alcoholism; biomarkers; gender; lipids; metabolomics

Indexed keywords

ACYLCARNITINE; ETHER LIPID; HIGH DENSITY LIPOPROTEIN; LYSOPHOSPHATIDYLCHOLINE; PHOSPHATIDYLCHOLINE; SPHINGOMYELIN; TRIACYLGLYCEROL; ALCOHOL; SPHINGOLIPID;

EID: 84880113662     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2013.55     Document Type: Article
Times cited : (79)

References (71)
  • 6
    • 0024351763 scopus 로고
    • Carbohydrate deficient transferrin: A marker for alcohol abuse
    • Kapur A, Wild G, Milford-Ward A, Triger DR. Carbohydrate deficient transferrin: a marker for alcohol abuse. BMJ 1989; 299: 427-431.
    • (1989) BMJ , vol.299 , pp. 427-431
    • Kapur, A.1    Wild, G.2    Milford-Ward, A.3    Triger, D.R.4
  • 7
    • 27744530929 scopus 로고    scopus 로고
    • Biomarkers for alcohol use and abuse: A summary
    • Peterson K. Biomarkers for alcohol use and abuse-a summary. Alcohol Res Health 2004; 28: 30-37. (Pubitemid 41595218)
    • (2004) Alcohol Research and Health , vol.28 , Issue.1 , pp. 30-37
    • Peterson, K.1
  • 9
    • 0036007687 scopus 로고    scopus 로고
    • Metabolomics - The link between genotypes and phenotypes
    • Fiehn O. Metabolomics-the link between genotypes and phenotypes. Plant Mol Biol 2002; 48: 155-171.
    • (2002) Plant Mol Biol , vol.48 , pp. 155-171
    • Fiehn, O.1
  • 14
    • 23844467739 scopus 로고    scopus 로고
    • KORA - A research platform for population based health research
    • Holle R, Happich M, Lowel H, Wichmann HE. KORA-a research platform for population based health research. Gesundheitswesen 2005; 67(Suppl 1): S19-S25.
    • (2005) Gesundheitswesen , vol.67 , Issue.SUPPL. 1
    • Holle, R.1    Happich, M.2    Lowel, H.3    Wichmann, H.E.4
  • 16
    • 23844472247 scopus 로고    scopus 로고
    • KORA-gen-resource for population genetics, controls and a broad spectrum of disease phenotypes
    • Wichmann HE, Gieger C, Illig T. KORA-gen-resource for population genetics, controls and a broad spectrum of disease phenotypes. Gesundheitswesen 2005; 67(Suppl 1): S26-S30.
    • (2005) Gesundheitswesen , vol.67 , Issue.SUPPL. 1
    • Wichmann, H.E.1    Gieger, C.2    Illig, T.3
  • 18
    • 84874417316 scopus 로고    scopus 로고
    • Effects of smoking and smoking cessation on human serum metabolite profile: Results from the KORA cohort study
    • Xu T, Holzapfel C, Dong X, Bader E, Yu Z, Prehn C et al. Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study. BMC Med 2013; 11: 60.
    • (2013) BMC Med , vol.11 , pp. 60
    • Xu, T.1    Holzapfel, C.2    Dong, X.3    Bader, E.4    Yu, Z.5    Prehn, C.6
  • 22
    • 57649167545 scopus 로고    scopus 로고
    • Metabolic profiling reveals distinct variations linked to nicotine consumption in humans-first results from the KORA study
    • Wang-Sattler R, Yu Y, Mittelstrass K, Lattka E, Altmaier E, Gieger C et al. Metabolic profiling reveals distinct variations linked to nicotine consumption in humans-first results from the KORA study. PLoS One 2008; 3: e3863.
    • (2008) PLoS One , vol.3
    • Wang-Sattler, R.1    Yu, Y.2    Mittelstrass, K.3    Lattka, E.4    Altmaier, E.5    Gieger, C.6
  • 24
    • 84862992788 scopus 로고    scopus 로고
    • Body fat free mass is associated with the serum metabolite profile in a population-based study
    • Jourdan C, Petersen AK, Gieger C, Doring A, Illig T, Wang-Sattler R et al. Body fat free mass is associated with the serum metabolite profile in a population-based study. PLoS One 2012; 7: e40009.
    • (2012) PLoS One , vol.7
    • Jourdan, C.1    Petersen, A.K.2    Gieger, C.3    Doring, A.4    Illig, T.5    Wang-Sattler, R.6
  • 25
    • 77953695390 scopus 로고    scopus 로고
    • Serum branched-chain amino acid to histidine ratio: A novel metabolomic biomarker of knee osteoarthritis
    • Zhai G, Wang-Sattler R, Hart DJ, Arden NK, Hakim AJ, Illig T et al. Serum branched-chain amino acid to histidine ratio: a novel metabolomic biomarker of knee osteoarthritis. Ann Rheum Dis 2010; 69:1227-1231.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1227-1231
    • Zhai, G.1    Wang-Sattler, R.2    Hart, D.J.3    Arden, N.K.4    Hakim, A.J.5    Illig, T.6
  • 27
    • 84855875727 scopus 로고    scopus 로고
    • Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics
    • Römisch-Margl W, Prehn C, Bogumil R, Röhring C, Suhre K, Adamski J. Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics. Metabolomics 2011; 8:133-142.
    • (2011) Metabolomics , vol.8 , pp. 133-142
    • Römisch-Margl, W.1    Prehn, C.2    Bogumil, R.3    Röhring, C.4    Suhre, K.5    Adamski, J.6
  • 29
    • 79953732420 scopus 로고    scopus 로고
    • Groothuis-Oudshoorn K. mice: Multivariate Imputation by Chained Equations in R
    • van Buuren S, Groothuis-Oudshoorn K. mice: Multivariate Imputation by Chained Equations in R. J Stat Software 2011; 45:1-67.
    • (2011) J Stat Software , vol.45 , pp. 1-67
    • Van Buuren, S.1
  • 30
    • 0000541109 scopus 로고
    • An extension of Shapiro and Wilks W test for normality to large samples
    • Royston P. An extension of Shapiro and Wilks W test for normality to large samples. Appl Stat 1982; 31:115-124.
    • (1982) Appl Stat , vol.31 , pp. 115-124
    • Royston, P.1
  • 31
    • 84950618101 scopus 로고
    • Constructing confidence sets using rank statistics
    • Bauer DF. Constructing confidence sets using rank statistics. J Am Stat Assoc 1972; 67: 687-690.
    • (1972) J Am Stat Assoc , vol.67 , pp. 687-690
    • Bauer, D.F.1
  • 32
    • 26444477556 scopus 로고    scopus 로고
    • 2nd edn. Chapter 3.5.1. Fisher's Exact Test for 2 x 2 Tables. Wiley: New York, NY, USA
    • Agresti A. Categorical Data Analysis. 2nd edn. Chapter 3.5.1. Fisher's Exact Test for 2 x 2 Tables. Wiley: New York, NY, USA, 2002, pp 91-101.
    • (2002) Categorical Data Analysis , pp. 91-101
    • Agresti, A.1
  • 33
    • 0002585592 scopus 로고
    • Generalized linear models
    • Chambers JM, Hastie TJ (eds) Wadsworth & Brooks/Cole: Pacific Grove, CA, USA
    • Hastie TJ, Pregibon D. Generalized linear models. In: Chambers JM, Hastie TJ (eds). Statistical Models in S. Wadsworth & Brooks/Cole: Pacific Grove, CA, USA, 1992.
    • (1992) Statistical Models in S
    • Hastie, T.J.1    Pregibon, D.2
  • 34
    • 0035478854 scopus 로고    scopus 로고
    • Random forests
    • DOI 10.1023/A:1010933404324
    • Breiman L. Random forests. Machine Learn 2001; 45: 5-32. (Pubitemid 32933532)
    • (2001) Machine Learning , vol.45 , Issue.1 , pp. 5-32
    • Breiman, L.1
  • 35
    • 62749184862 scopus 로고    scopus 로고
    • Roles and regulation of secretory and lysosomal acid sphingomyelinase
    • Jenkins RW, Canals D, Hannun YA. Roles and regulation of secretory and lysosomal acid sphingomyelinase. Cell Signal 2009; 21: 836-846.
    • (2009) Cell Signal , vol.21 , pp. 836-846
    • Jenkins, R.W.1    Canals, D.2    Hannun, Y.A.3
  • 36
    • 0033662390 scopus 로고    scopus 로고
    • Activation of neutral sphingomyelinase participates in ethanol-induced apoptosis in Hep G2 cells
    • Liu JJ, Wang JY, Hertervig E, Cheng Y, Nilsson A, Duan RD. Activation of neutral sphingomyelinase participates in ethanol-induced apoptosis in Hep G2 cells. Alcohol Alcohol 2000; 35: 569-573.
    • (2000) Alcohol Alcohol , vol.35 , pp. 569-573
    • Liu, J.J.1    Wang, J.Y.2    Hertervig, E.3    Cheng, Y.4    Nilsson, A.5    Duan, R.D.6
  • 38
  • 40
    • 24144486191 scopus 로고    scopus 로고
    • Ethanol-induced changes in the content of triglycerides, ceramides, and glucosylceramides in cultured neurons
    • DOI 10.1097/01.alc.0000175011.22307.61
    • Saito M, Saito M, Cooper TB, Vadasz C. Ethanol-induced changes in the content of triglycerides, ceramides, and glucosylceramides in cultured neurons. Alcohol Clin Exp Res 2005; 29:1374-1383. (Pubitemid 41243361)
    • (2005) Alcoholism: Clinical and Experimental Research , vol.29 , Issue.8 , pp. 1374-1383
    • Saito, M.1    Saito, M.2    Cooper, T.B.3    Vadasz, C.4
  • 41
    • 67349084190 scopus 로고    scopus 로고
    • Effects of ethanol and lipopolysaccharide on the sphingomyelin cycle in rat hepatocytes
    • Viktorov AV, Yurkiv VA. Effects of ethanol and lipopolysaccharide on the sphingomyelin cycle in rat hepatocytes. Bull Exp Biol Med 2008; 146: 753-755.
    • (2008) Bull Exp Biol Med , vol.146 , pp. 753-755
    • Viktorov, A.V.1    Yurkiv, V.A.2
  • 42
    • 74049095218 scopus 로고    scopus 로고
    • Ncreased acid sphingomyelinase activity in peripheral blood cells of acutely intoxicated patients with alcohol dependence
    • Reichel M, Greiner E, Richter-Schmidinger T, Yedibela O, Tripal P, Jacobi A et al. ncreased acid sphingomyelinase activity in peripheral blood cells of acutely intoxicated patients with alcohol dependence. Alcohol Clin Exp Res 2010; 34: 46-50.
    • (2010) Alcohol Clin Exp Res , vol.34 , pp. 46-50
    • Reichel, M.1    Greiner, E.2    Richter-Schmidinger, T.3    Yedibela, O.4    Tripal, P.5    Jacobi, A.6
  • 43
    • 70249089999 scopus 로고    scopus 로고
    • Preliminary evaluation of phosphatidylethanol and alcohol consumption in patients with liver disease and hypertension
    • Stewart SH, Reuben A, Brzezinski WA, Koch DG, Basile J, Randall PK etal. Preliminary evaluation of phosphatidylethanol and alcohol consumption in patients with liver disease and hypertension. Alcohol Alcohol 2009; 44: 464-467.
    • (2009) Alcohol Alcohol , vol.44 , pp. 464-467
    • Stewart, S.H.1    Reuben, A.2    Brzezinski, W.A.3    Koch, D.G.4    Basile, J.5    Randall, P.K.6
  • 44
    • 0023106038 scopus 로고
    • Formation of phosphatidylethanol in rat brain by phospholipase D
    • DOI 10.1016/0006-291X(87)91507-5
    • Gustavsson L, Alling C. Formation of phosphatidylethanol in rat brain by phospholipase D. Biochem Biophys Res Commun 1987; 142: 958-963. (Pubitemid 17021126)
    • (1987) Biochemical and Biophysical Research Communications , vol.142 , Issue.3 , pp. 958-963
    • Gustavsson, L.1    Alling, C.2
  • 45
    • 0023229006 scopus 로고
    • Phosphatidylethanol formation via transphosphatidylation by rat brain synaptosomal phospholipase D
    • DOI 10.1111/j.1471-4159.1987.tb05707.x
    • Kobayashi M, Kanfer JN. Phosphatidylethanol formation viatransphosphatidylation by rat brain synaptosomal phospholipase D. J Neurochem 1987; 48:1597-1603. (Pubitemid 17068749)
    • (1987) Journal of Neurochemistry , vol.48 , Issue.5 , pp. 1597-1603
    • Kobayashi, M.1    Kanfer, J.N.2
  • 47
    • 67650081281 scopus 로고    scopus 로고
    • Molecular species of the alcohol biomarker phosphatidylethanol in human blood measured by LC-MS
    • Helander A, Zheng Y. Molecular species of the alcohol biomarker phosphatidylethanol in human blood measured by LC-MS. Clin Chem 2009; 55: 1395-1405.
    • (2009) Clin Chem , vol.55 , pp. 1395-1405
    • Helander, A.1    Zheng, Y.2
  • 48
    • 80054847239 scopus 로고    scopus 로고
    • Quantitative profiling of phosphatidylethanol molecular species in human blood by liquid chromatography high resolution mass spectrometry
    • Nalesso A, Viel G, Cecchetto G, Mioni D, Pessa G, Favretto D et al. Quantitative profiling of phosphatidylethanol molecular species in human blood by liquid chromatography high resolution mass spectrometry. J Chromatogr A 2011; 1218: 8423-8431.
    • (2011) J Chromatogr A , vol.1218 , pp. 8423-8431
    • Nalesso, A.1    Viel, G.2    Cecchetto, G.3    Mioni, D.4    Pessa, G.5    Favretto, D.6
  • 49
    • 0033983832 scopus 로고    scopus 로고
    • Characterization of plasma unsaturated lysophosphatidylcholines in human and rat
    • DOI 10.1042/0264-6021:3450061
    • Croset M, Brossard N, Polette A, Lagarde M. Characterization of plasma unsaturated lysophosphatidylcholines in human and rat. Biochem J 2000; 345(Pt 1): 61-67. (Pubitemid 30060104)
    • (2000) Biochemical Journal , vol.345 , Issue.1 , pp. 61-67
    • Croset, M.1    Brossard, N.2    Polette, A.3    Lagarde, M.4
  • 50
    • 0018797112 scopus 로고
    • Cytolytic and membrane-perturbing properties of lysophosphatidylcholine
    • Weltzien HU. Cytolytic and membrane-perturbing properties of lysophosphatidylcholine. Biochim Biophys Acta 1979; 559: 259-287.
    • (1979) Biochim Biophys Acta , vol.559 , pp. 259-287
    • Weltzien, H.U.1
  • 51
    • 37549004312 scopus 로고    scopus 로고
    • Role of lysophosphatidylcholine (LPC) in atherosclerosis
    • Matsumoto T, Kobayashi T, Kamata K. Role of lysophosphatidylcholine (LPC) in atherosclerosis. Curr Med Chem 2007; 14: 3209-3220.
    • (2007) Curr Med Chem , vol.14 , pp. 3209-3220
    • Matsumoto, T.1    Kobayashi, T.2    Kamata, K.3
  • 52
    • 0035960594 scopus 로고    scopus 로고
    • + channel function
    • Wang J, Wang H, Han H, Zhang Y, Yang B, Nattel S et al. Phospholipid metabolite 1-palmitoyl-lysophosphatidylcholine enhances human ether-a-go-go-related gene (HERG) K(+) channel function. Circulation 2001; 104: 2645-2648. (Pubitemid 33108127)
    • (2001) Circulation , vol.104 , Issue.22 , pp. 2645-2648
    • Wang, J.1    Wang, H.2    Han, H.3    Zhang, Y.4    Yang, B.5    Nattel, S.6    Wang, Z.7
  • 53
    • 77949498424 scopus 로고    scopus 로고
    • Plasma levels of lecithin:cholesterol acyltransferase and risk of future coronary artery disease in apparently healthy men and women: A prospective case-control analysis nested in the EPIC-Norfolk population study
    • Holleboom AG, Kuivenhoven JA, Vergeer M, Hovingh GK, van Miert JN, Wareham NJ et al. Plasma levels of lecithin:cholesterol acyltransferase and risk of future coronary artery disease in apparently healthy men and women: a prospective case-control analysis nested in the EPIC-Norfolk population study. J Lipid Res 2010; 51: 416-421.
    • (2010) J Lipid Res , vol.51 , pp. 416-421
    • Holleboom, A.G.1    Kuivenhoven, J.A.2    Vergeer, M.3    Hovingh, G.K.4    Van Miert, J.N.5    Wareham, N.J.6
  • 54
    • 0037365489 scopus 로고    scopus 로고
    • Plasma concentrations of LPL and LCAT are in putative association with females and alcohol use which are independent negative risk factors for coronary atherosclerosis among Japanese
    • DOI 10.1016/S0009-8981(03)00021-4
    • Goto A, Sasai K, Suzuki S, Fukutomi T, Ito S, Matsushita T et al. Plasma concentrations of LPL and LCAT are in putative association with females and alcohol use which are independent negative risk factors for coronary atherosclerosis among Japanese. Clin Chim Acta 2003; 329: 69-76. (Pubitemid 36183483)
    • (2003) Clinica Chimica Acta , vol.329 , Issue.1-2 , pp. 69-76
    • Goto, A.1    Sasai, K.2    Suzuki, S.3    Fukutomi, T.4    Ito, S.5    Matsushita, T.6    Okamoto, M.7    Suzuki, T.8    Itoh, M.9    Okumura-Noji, K.10    Yokoyama, S.11
  • 55
    • 31344464596 scopus 로고    scopus 로고
    • Role of cytochrome P450 in phospholipase A2- and arachidonic acid-mediated cytotoxicity
    • DOI 10.1016/j.freeradbiomed.2005.10.044, PII S0891584905006398
    • Caro AA, Cederbaum AI. Role of cytochrome P450 in phospholipase A2-and arachidonic acid-mediated cytotoxicity. Free Radic Biol Med 2006; 40: 364-375. (Pubitemid 43139672)
    • (2006) Free Radical Biology and Medicine , vol.40 , Issue.3 , pp. 364-375
    • Caro, A.A.1    Cederbaum, A.I.2
  • 57
    • 0035060506 scopus 로고    scopus 로고
    • Fatty acid ethyl esters in liver and adipose tissues as postmortem markers for ethanol intake
    • Salem RO, Refaai MA, Cluette-Brown JE, Russo JW, Laposata M. Fatty acid ethyl esters in liver and adipose tissues as postmortem markers for ethanol intake. Clin Chem 2001; 47: 722-725. (Pubitemid 32275816)
    • (2001) Clinical Chemistry , vol.47 , Issue.4 , pp. 722-725
    • Salem, R.O.1    Refaai, M.A.2    Cluette-Brown, J.E.3    Russo, J.W.4    Laposata, M.5
  • 58
    • 0035124967 scopus 로고    scopus 로고
    • Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles
    • DOI 10.1136/gut.48.2.198
    • Hopkins MJ, Sharp R, Macfarlane GT. Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles. Gut 2001; 48: 198-205. (Pubitemid 32141843)
    • (2001) Gut , vol.48 , Issue.2 , pp. 198-205
    • Hopkins, M.J.1    Sharp, R.2    Macfarlane, G.T.3
  • 59
    • 0032918589 scopus 로고    scopus 로고
    • Pentadecanoic acid in serum as a marker for intake of milk fat: Relations between intake of milk fat and metabolic risk factors
    • Smedman AE, Gustafsson IB, Berglund LG, Vessby BO. Pentadecanoic acid in serum as a marker for intake of milk fat: relations between intake of milk fat and metabolic risk factors. Am J Clin Nutr 1999; 69: 22-29. (Pubitemid 29031247)
    • (1999) American Journal of Clinical Nutrition , vol.69 , Issue.1 , pp. 22-29
    • Smedman, A.E.M.1    Gustafsson, I.-B.2    Berglund, L.G.T.3    Vessby, B.O.H.4
  • 60
    • 0026217162 scopus 로고
    • Synthesis and biohydrogenation of fatty acids by ruminal microorganisms in vitro
    • Wu Z, Palmquist DL. Synthesis and biohydrogenation of fatty acids by ruminal microorganisms in vitro. J Dairy Sci 1991; 74: 3035-3046.
    • (1991) J Dairy Sci , vol.74 , pp. 3035-3046
    • Wu, Z.1    Palmquist, D.L.2
  • 62
    • 17044364699 scopus 로고    scopus 로고
    • Food and nutrient intake, anthropometric measurements and smoking according to alcohol consumption in the EPIC Heidelberg study
    • DOI 10.1159/000084173
    • Ruf T, Nagel G, Altenburg HP, Miller AB, Thorand B. Food and nutrient intake, anthropometric measurements and smoking according to alcohol consumption in the EPIC Heidelberg study. Ann Nutr Metab 2005; 49: 16-25. (Pubitemid 41094829)
    • (2005) Annals of Nutrition and Metabolism , vol.49 , Issue.1 , pp. 16-25
    • Ruf, T.1    Nagel, G.2    Altenburg, H.-P.3    Miller, A.B.4    Thorand, B.5
  • 63
    • 0034862315 scopus 로고    scopus 로고
    • Do eating habits differ according to alcohol consumption? Results of a study of the French cohort of the European Prospective Investigation into Cancer and Nutrition (E3N-EPIC)
    • Kesse E, Clavel-Chapelon F, Slimani N, van Liere M. Do eating habits differ according to alcohol consumption? Results of a study of the French cohort of the European Prospective Investigation into Cancer and Nutrition (E3N-EPIC). Am J Clin Nutr 2001; 74: 322-327. (Pubitemid 32802017)
    • (2001) American Journal of Clinical Nutrition , vol.74 , Issue.3 , pp. 322-327
    • Kesse, E.1    Clavel-Chapelon, F.2    Slimani, N.3    Van Liere, M.4
  • 64
    • 0035102918 scopus 로고    scopus 로고
    • Plasmalogens: Biosynthesis and functions
    • DOI 10.1016/S0163-7827(01)00003-0, PII S0163782701000030
    • Nagan N, Zoeller RA. Plasmalogens: biosynthesis and functions. Prog Lipid Res 2001; 40: 199-229. (Pubitemid 32220187)
    • (2001) Progress in Lipid Research , vol.40 , Issue.3 , pp. 199-229
    • Nagan, N.1    Zoeller, R.A.2
  • 65
    • 0028944870 scopus 로고
    • Platelet-activating factor: The biosynthetic and catabolic enzymes
    • Snyder F. Platelet-activating factor: the biosynthetic and catabolic enzymes. Biochem J 1995; 305(Pt 3): 689-705.
    • (1995) Biochem J , vol.305 , Issue.PART 3 , pp. 689-705
    • Snyder, F.1
  • 67
    • 0023683702 scopus 로고
    • Platelet thromboxane formation capacity after ethanol withdrawal in chronic alcoholics
    • Hillbom M, Neiman J. Platelet thromboxane formation capacity after ethanol withdrawal in chronic alcoholics. Haemostasis 1988; 18: 170-178.
    • (1988) Haemostasis , vol.18 , pp. 170-178
    • Hillbom, M.1    Neiman, J.2
  • 68
    • 0022512588 scopus 로고
    • Platelet function defects in chronic alcoholism
    • Mikhailidis DP, Jenkins WJ, Barradas MA, Jeremy JY, Dandona P. Platelet function defects in chronic alcoholism. Br Med J (Clin Res Ed) 1986; 293: 715-718. (Pubitemid 16025283)
    • (1986) British Medical Journal , vol.293 , Issue.6549 , pp. 715-718
    • Mikhailidis, D.P.1    Barradas, M.A.2    Jeremy, J.Y.3
  • 69
    • 24044492904 scopus 로고    scopus 로고
    • Effects of alcohol on hemostasis
    • Salem RO, Laposata M. Effects of alcohol on hemostasis. Am J Clin Pathol 2005; 123(Suppl): S96-105.
    • (2005) Am J Clin Pathol , vol.123 , Issue.SUPPL.
    • Salem, R.O.1    Laposata, M.2
  • 70
    • 0032724388 scopus 로고    scopus 로고
    • The risk of acute major upper gastrointestinal bleeding among users of aspirin and ibuprofen at various levels of alcohol consumption
    • Kaufman DW, Kelly JP, Wiholm BE, Laszlo A, Sheehan JE, Koff RS et al. The risk of acute major upper gastrointestinal bleeding among users of aspirin and ibuprofen at various levels of alcohol consumption. Am J Gastroenterol 1999; 94: 3189-3196.
    • (1999) Am J Gastroenterol , vol.94 , pp. 3189-3196
    • Kaufman, D.W.1    Kelly, J.P.2    Wiholm, B.E.3    Laszlo, A.4    Sheehan, J.E.5    Koff, R.S.6
  • 71
    • 79961151703 scopus 로고    scopus 로고
    • Association between markers of fatty liver disease and impaired glucose regulation in men and women from the general population: The KORA-F4-study
    • Ruckert IM, Heier M, Rathmann W, Baumeister SE, Doring A, Meisinger C. Association between markers of fatty liver disease and impaired glucose regulation in men and women from the general population: the KORA-F4-study. PLoS One 2011; 6: e22932.
    • (2011) PLoS One , vol.6
    • Ruckert, I.M.1    Heier, M.2    Rathmann, W.3    Baumeister, S.E.4    Doring, A.5    Meisinger, C.6


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