Augmenter of liver regeneration gene therapy using a Novel Minicircle DNA vector alleviates liver fibrosis in rats

Human Gene Therapy

Volumn 27, Issue 11, 2016, Pages 880-891

  Wu, Xin ^a,b   Liu, Guangze ^b   Mu, Mao ^a,b   Peng, Yuting ^a,b   Li, Xiumei ^b   Deng, Lisi ^c   Zhang, Zhenwei ^b   Chen, Meijuan ^b   You, Song ^a   Kong, Xiangping ^b  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b Department of Oncology 458th Hospital of PLA   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

minicircle DNA vector, high level expression, augmenter of liver regeneration (ALR), gene therapy, liver fibrosis, hydrodynamics based transfection (HBT)

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; MINICIRCLE DNA; PLASMID DNA; PLATELET DERIVED GROWTH FACTOR BB; TRANSFORMING GROWTH FACTOR BETA1; CIRCULAR DNA; DNA BINDING PROTEIN; MLL2 PROTEIN, HUMAN; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DNA VECTOR; GENE EXPRESSION; GENE THERAPY; HUMAN; HUMAN CELL; HYDRODYNAMICS BASED TRANSFECTION; LIVER FIBROSIS; LIVER REGENERATION; MALE; NONHUMAN; RAT; STELLATE CELL; ADMINISTRATION AND DOSAGE; ANIMAL; CYTOLOGY; GENE VECTOR; GENETICS; HEPATIC STELLATE CELL; LIVER CIRRHOSIS; SPRAGUE DAWLEY RAT;

ANIMALS; DNA, CIRCULAR; DNA-BINDING PROTEINS; GENETIC THERAPY; GENETIC VECTORS; HEPATIC STELLATE CELLS; LIVER CIRRHOSIS; LIVER REGENERATION; MALE; NEOPLASM PROTEINS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84997236581     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2016.006     Document Type: Article

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