Repression of cytochrome P450 activity in human hepatocytes in vitro by a novel hepatotrophic factor, augmenter of liver regeneration

Journal of Pharmacology and Experimental Therapeutics

Volumn 316, Issue 2, 2006, Pages 822-829

  Thasler, Wolfgang E ^a,b   Dayoub, Rania ^a   Mühlbauer, Marcus ^a   Hellerbrand, Claus ^a   Singer, Thomas ^c   Gräbe, Anja ^a   Jauch, Karl Walter ^b   Schlitt, Hans Jürgen ^a   Weiss, Thomas S ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTANE RECEPTOR; AROMATIC HYDROCARBON; AUGMENTER OF LIVER REGENERATION; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; GLUCURONOSYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PREGNANE X RECEPTOR; RECEPTOR; SCATTER FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME REPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; LIVER METABOLISM; LIVER REGENERATION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RNA ANALYSIS; WESTERN BLOTTING;

CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; CYTOCHROME REDUCTASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HEPATOCYTES; HUMANS; RECOMBINANT PROTEINS; TIME FACTORS;

EID: 31144440344     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.094201     Document Type: Article

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