메뉴 건너뛰기




Volumn 39, Issue 2, 2017, Pages 99-111

Dendritic cells in central nervous system autoimmunity

Author keywords

Central nervous system; Dendritic cells; Experimental autoimmune encephalomyelitis; Multiple sclerosis; T helper cells

Indexed keywords

ADAPTIVE IMMUNITY; ANTIGEN PRESENTATION; AUTOIMMUNITY; CENTRAL NERVOUS SYSTEM; CROSS PRESENTATION; DENDRITIC CELL; DISEASE MODEL; HUMAN; IMMUNOSURVEILLANCE; INNATE IMMUNITY; LYMPHOCYTE FUNCTION; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; REVIEW; SENSORY NERVE; STEADY STATE; T CELL RESPONSE; T LYMPHOCYTE; ANIMAL; ANIMAL MODEL; ANTIGEN PRESENTING CELL; CLASSIFICATION; DRUG DEVELOPMENT; DRUG EFFECTS; GENETICS; HELPER CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; INFLAMMATION; LYMPHOID TISSUE; METABOLISM; MOUSE; MYELIN SHEATH; PATHOLOGY; PHENOTYPE; T LYMPHOCYTE SUBPOPULATION;

EID: 84997208452     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-016-0608-7     Document Type: Review
Times cited : (36)

References (140)
  • 1
    • 0015619335 scopus 로고
    • Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution
    • COI: 1:STN:280:DyaE3s7ntFejsw%3D%3D, PID: 4573839
    • Steinman RM, Steinman RM, Cohn ZA (1973) Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J Exp Med 137:1142–1162. doi:10.1084/jem.137.5.1142
    • (1973) J Exp Med , vol.137 , pp. 1142-1162
    • Steinman, R.M.1    Steinman, R.M.2    Cohn, Z.A.3
  • 2
    • 34447120188 scopus 로고    scopus 로고
    • HLA-DR15 haplotype and multiple sclerosis: a HuGE review
    • PID: 17329717
    • Schmidt H, Schmidt H, Schmidt H et al (2007) HLA-DR15 haplotype and multiple sclerosis: a HuGE review. Am J Epidemiol 165:1097–1109. doi:10.1093/aje/kwk118
    • (2007) Am J Epidemiol , vol.165 , pp. 1097-1109
    • Schmidt, H.1    Schmidt, H.2    Schmidt, H.3
  • 3
    • 80051684615 scopus 로고    scopus 로고
    • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
    • International Multiple Sclerosis Genetics Consortium, Wellcome Trust Case Control Consortium 2, Sawcer S et al (2011) Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 476:214–219. doi:10.1038/nature10251
    • (2011) Nature , vol.476 , pp. 214-219
    • Sawcer, S.1
  • 4
    • 0034278725 scopus 로고    scopus 로고
    • Dendritic cell regulation of TH1-TH2 development
    • COI: 1:CAS:528:DC%2BD3cXmsVyitbc%3D, PID: 10973276
    • Moser M, Murphy KM (2000) Dendritic cell regulation of TH1-TH2 development. Nat Immunol 1:199–205. doi:10.1038/79734
    • (2000) Nat Immunol , vol.1 , pp. 199-205
    • Moser, M.1    Murphy, K.M.2
  • 5
    • 0033546053 scopus 로고    scopus 로고
    • The nature of the principal type 1 interferon-producing cells in human blood
    • COI: 1:CAS:528:DyaK1MXjvFSqsbg%3D
    • Siegal FP, Kadowaki N, Shodell M et al (1999) The nature of the principal type 1 interferon-producing cells in human blood. Science (New York, NY) 284:1835–1837
    • (1999) Science (New York, NY) , vol.284 , pp. 1835-1837
    • Siegal, F.P.1    Kadowaki, N.2    Shodell, M.3
  • 6
    • 0032773794 scopus 로고    scopus 로고
    • Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon
    • COI: 1:CAS:528:DyaK1MXltVyjsbk%3D, PID: 10426316
    • Cella M, Jarrossay D, Facchetti F et al (1999) Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon. Nat Med 5:919–923. doi:10.1038/11360
    • (1999) Nat Med , vol.5 , pp. 919-923
    • Cella, M.1    Jarrossay, D.2    Facchetti, F.3
  • 7
    • 84875528275 scopus 로고    scopus 로고
    • The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting
    • COI: 1:CAS:528:DC%2BC3sXnsFClsbg%3D, PID: 23516985
    • Merad M, Sathe P, Helft J et al (2013) The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. Annu Rev Immunol 31:563–604. doi:10.1146/annurev-immunol-020711-074950
    • (2013) Annu Rev Immunol , vol.31 , pp. 563-604
    • Merad, M.1    Sathe, P.2    Helft, J.3
  • 8
    • 84905107360 scopus 로고    scopus 로고
    • Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny
    • COI: 1:CAS:528:DC%2BC2cXhtFygsr%2FI, PID: 25033907
    • Guilliams M, Ginhoux F, Jakubzick C et al (2014) Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny. Nat Rev Immunol 14:571–578. doi:10.1038/nri3712
    • (2014) Nat Rev Immunol , vol.14 , pp. 571-578
    • Guilliams, M.1    Ginhoux, F.2    Jakubzick, C.3
  • 9
    • 84880838451 scopus 로고    scopus 로고
    • Origin of monocytes and macrophages in a committed progenitor
    • COI: 1:CAS:528:DC%2BC3sXhtVaku7%2FO, PID: 23812096
    • Hettinger J, Richards DM, Hansson J et al (2013) Origin of monocytes and macrophages in a committed progenitor. Nat Immunol 14:821–830. doi:10.1038/ni.2638
    • (2013) Nat Immunol , vol.14 , pp. 821-830
    • Hettinger, J.1    Richards, D.M.2    Hansson, J.3
  • 10
    • 34547788180 scopus 로고    scopus 로고
    • A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
    • COI: 1:CAS:528:DC%2BD2sXptVyjs7k%3D, PID: 17620361
    • Coombes JL, Siddiqui KRR, Arancibia-Cárcamo CV et al (2007) A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med 204:1757–1764. doi:10.1084/jem.20070590
    • (2007) J Exp Med , vol.204 , pp. 1757-1764
    • Coombes, J.L.1    Siddiqui, K.R.R.2    Arancibia-Cárcamo, C.V.3
  • 11
    • 84883172356 scopus 로고    scopus 로고
    • Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens
    • COI: 1:CAS:528:DC%2BC3sXht1WhsLjP, PID: 23913046
    • Satpathy AT, Briseño CG, Lee JS et al (2013) Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol 14:937–948. doi:10.1038/ni.2679
    • (2013) Nat Immunol , vol.14 , pp. 937-948
    • Satpathy, A.T.1    Briseño, C.G.2    Lee, J.S.3
  • 12
    • 84931394611 scopus 로고    scopus 로고
    • Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow
    • COI: 1:CAS:528:DC%2BC2MXhtFSktLjN, PID: 26054720
    • Schlitzer A, Sivakamasundari V, Chen J et al (2015) Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow. Nat Immunol 16:718–728. doi:10.1038/ni.3200
    • (2015) Nat Immunol , vol.16 , pp. 718-728
    • Schlitzer, A.1    Sivakamasundari, V.2    Chen, J.3
  • 13
    • 84931561466 scopus 로고    scopus 로고
    • Dendritic cells and monocyte-derived cells: two complementary and integrated functional systems
    • COI: 1:CAS:528:DC%2BC2MXot1WntLw%3D, PID: 25957517
    • Schlitzer A, McGovern N, Ginhoux F (2015) Dendritic cells and monocyte-derived cells: two complementary and integrated functional systems. Semin Cell Dev Biol 41:9–22. doi:10.1016/j.semcdb.2015.03.011
    • (2015) Semin Cell Dev Biol , vol.41 , pp. 9-22
    • Schlitzer, A.1    McGovern, N.2    Ginhoux, F.3
  • 14
    • 84969785370 scopus 로고    scopus 로고
    • Transcriptional control of dendritic cell development
    • PID: 26735697
    • Murphy TL, Grajales-Reyes GE, Wu X et al (2016) Transcriptional control of dendritic cell development. Annu Rev Immunol 34:93–119. doi:10.1146/annurev-immunol-032713-120204
    • (2016) Annu Rev Immunol , vol.34 , pp. 93-119
    • Murphy, T.L.1    Grajales-Reyes, G.E.2    Wu, X.3
  • 15
    • 84929661740 scopus 로고    scopus 로고
    • Klf4 expression in conventional dendritic cells is required for T helper 2 cell responses
    • COI: 1:CAS:528:DC%2BC2MXoslCns7w%3D, PID: 25992862
    • Tussiwand R, Everts B, Grajales-Reyes GE et al (2015) Klf4 expression in conventional dendritic cells is required for T helper 2 cell responses. Immunity 42:916–928. doi:10.1016/j.immuni.2015.04.017
    • (2015) Immunity , vol.42 , pp. 916-928
    • Tussiwand, R.1    Everts, B.2    Grajales-Reyes, G.E.3
  • 16
    • 84925465211 scopus 로고    scopus 로고
    • Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
    • PID: 25470051
    • Gomez Perdiguero E, Klapproth K, Schulz C et al (2015) Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors. Nature 518:547–551. doi:10.1038/nature13989
    • (2015) Nature , vol.518 , pp. 547-551
    • Gomez Perdiguero, E.1    Klapproth, K.2    Schulz, C.3
  • 17
    • 67249158956 scopus 로고    scopus 로고
    • Identification of a dendritic cell receptor that couples sensing of necrosis to immunity
    • COI: 1:CAS:528:DC%2BD1MXhvFKjtLs%3D, PID: 19219027
    • Sancho D, Joffre OP, Keller AM et al (2009) Identification of a dendritic cell receptor that couples sensing of necrosis to immunity. Nature 458:899–903. doi:10.1038/nature07750
    • (2009) Nature , vol.458 , pp. 899-903
    • Sancho, D.1    Joffre, O.P.2    Keller, A.M.3
  • 18
    • 84859993076 scopus 로고    scopus 로고
    • The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments
    • COI: 1:CAS:528:DC%2BC38XltF2jtb0%3D, PID: 22483802
    • Zhang J-G, Czabotar PE, Policheni AN et al (2012) The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments. Immunity 36:646–657. doi:10.1016/j.immuni.2012.03.009
    • (2012) Immunity , vol.36 , pp. 646-657
    • Zhang, J.-G.1    Czabotar, P.E.2    Policheni, A.N.3
  • 19
    • 84859957011 scopus 로고    scopus 로고
    • F-actin is an evolutionarily conserved damage-associated molecular pattern recognized by DNGR-1, a receptor for dead cells
    • COI: 1:CAS:528:DC%2BC38XltFyqtLw%3D, PID: 22483800
    • Ahrens S, Zelenay S, Sancho D et al (2012) F-actin is an evolutionarily conserved damage-associated molecular pattern recognized by DNGR-1, a receptor for dead cells. Immunity 36:635–645. doi:10.1016/j.immuni.2012.03.008
    • (2012) Immunity , vol.36 , pp. 635-645
    • Ahrens, S.1    Zelenay, S.2    Sancho, D.3
  • 20
    • 84860256323 scopus 로고    scopus 로고
    • The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice
    • COI: 1:CAS:528:DC%2BC38Xmslyqu7c%3D, PID: 22505455
    • Iborra S, Izquierdo HM, Martínez-López M et al (2012) The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice. J Clin Invest 122:1628–1643. doi:10.1172/JCI60660
    • (2012) J Clin Invest , vol.122 , pp. 1628-1643
    • Iborra, S.1    Izquierdo, H.M.2    Martínez-López, M.3
  • 21
    • 84882786445 scopus 로고    scopus 로고
    • Genetic tracing via DNGR-1 expression history defines dendritic cells as a hematopoietic lineage
    • COI: 1:CAS:528:DC%2BC3sXht1yhsL7F, PID: 23953115
    • Schraml BU, van Blijswijk J, Zelenay S et al (2013) Genetic tracing via DNGR-1 expression history defines dendritic cells as a hematopoietic lineage. Cell 154:843–858. doi:10.1016/j.cell.2013.07.014
    • (2013) Cell , vol.154 , pp. 843-858
    • Schraml, B.U.1    van Blijswijk, J.2    Zelenay, S.3
  • 22
    • 84864297838 scopus 로고    scopus 로고
    • Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages
    • COI: 1:CAS:528:DC%2BC38XoslSiu7g%3D, PID: 22615127
    • Satpathy AT, Kc W, Albring JC et al (2012) Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages. J Exp Med 209:1135–1152. doi:10.1084/jem.20120030
    • (2012) J Exp Med , vol.209 , pp. 1135-1152
    • Satpathy, A.T.1    Kc, W.2    Albring, J.C.3
  • 23
    • 84864296761 scopus 로고    scopus 로고
    • Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage
    • COI: 1:CAS:528:DC%2BC38XoslSiu7k%3D, PID: 22615130
    • Meredith MM, Liu K, Darrasse-Jèze G et al (2012) Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage. J Exp Med 209:1153–1165. doi:10.1084/jem.20112675
    • (2012) J Exp Med , vol.209 , pp. 1153-1165
    • Meredith, M.M.1    Liu, K.2    Darrasse-Jèze, G.3
  • 24
    • 84866370825 scopus 로고    scopus 로고
    • Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state
    • COI: 1:CAS:528:DC%2BC38XhtlWns7jI, PID: 22851594
    • Meredith MM, Liu K, Kamphorst AO et al (2012) Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state. J Exp Med 209:1583–1593. doi:10.1084/jem.20121003
    • (2012) J Exp Med , vol.209 , pp. 1583-1593
    • Meredith, M.M.1    Liu, K.2    Kamphorst, A.O.3
  • 25
    • 84878863691 scopus 로고    scopus 로고
    • MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis
    • International Multiple Sclerosis Genetics Consortium, Lill CM, Schjeide B-MM et al (2013) MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis. Brain 136:1778–1782. doi:10.1093/brain/awt101
    • (2013) Brain , vol.136 , pp. 1778-1782
    • Lill, C.M.1    Schjeide, B.-M.M.2
  • 26
    • 84941735780 scopus 로고    scopus 로고
    • The cytokine GM-CSF drives the inflammatory signature of CCR2(+) monocytes and licenses autoimmunity
    • COI: 1:CAS:528:DC%2BC2MXhsVaqsbfJ, PID: 26341401
    • Croxford AL, Lanzinger M, Hartmann FJ et al (2015) The cytokine GM-CSF drives the inflammatory signature of CCR2(+) monocytes and licenses autoimmunity. Immunity 43:502–514. doi:10.1016/j.immuni.2015.08.010
    • (2015) Immunity , vol.43 , pp. 502-514
    • Croxford, A.L.1    Lanzinger, M.2    Hartmann, F.J.3
  • 27
    • 84974715217 scopus 로고    scopus 로고
    • Distinct transcriptional programs control cross-priming in classical and monocyte-derived dendritic cells
    • PID: 27264183
    • Briseño CG, Haldar M, Kretzer NM et al (2016) Distinct transcriptional programs control cross-priming in classical and monocyte-derived dendritic cells. Cell Rep 15:2462–2474. doi:10.1016/j.celrep.2016.05.025
    • (2016) Cell Rep , vol.15 , pp. 2462-2474
    • Briseño, C.G.1    Haldar, M.2    Kretzer, N.M.3
  • 29
    • 84871307366 scopus 로고    scopus 로고
    • CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis
    • COI: 1:CAS:528:DC%2BC38XhsFWhs7zM, PID: 22936024
    • Tamoutounour S, Tamoutounour S, Tamoutounour S et al (2012) CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis. Eur J Immunol 42:3150–3166. doi:10.1002/eji.201242847
    • (2012) Eur J Immunol , vol.42 , pp. 3150-3166
    • Tamoutounour, S.1    Tamoutounour, S.2    Tamoutounour, S.3
  • 30
    • 84934296644 scopus 로고    scopus 로고
    • Microglia versus myeloid cell nomenclature during brain inflammation
    • Greter M, Lelios I, Croxford AL (2015) Microglia versus myeloid cell nomenclature during brain inflammation. Front Immun 6:249. doi:10.3389/fimmu.2015.00249
    • (2015) Front Immun , vol.6 , pp. 249
    • Greter, M.1    Lelios, I.2    Croxford, A.L.3
  • 31
    • 84911016319 scopus 로고    scopus 로고
    • High-dimensional analysis of the murine myeloid cell system
    • COI: 1:CAS:528:DC%2BC2cXhslelsLbK, PID: 25306126
    • Becher B, Schlitzer A, Chen J et al (2014) High-dimensional analysis of the murine myeloid cell system. Nat Immunol 15:1181–1189. doi:10.1038/ni.3006
    • (2014) Nat Immunol , vol.15 , pp. 1181-1189
    • Becher, B.1    Schlitzer, A.2    Chen, J.3
  • 32
    • 65249089638 scopus 로고    scopus 로고
    • In vivo analysis of dendritic cell development and homeostasis
    • COI: 1:CAS:528:DC%2BD1MXksVOltrg%3D
    • Liu K, Victora GD, Schwickert TA et al (2009) In vivo analysis of dendritic cell development and homeostasis. Science (New York, NY) 324:392–397. doi:10.1126/science.1170540
    • (2009) Science (New York, NY) , vol.324 , pp. 392-397
    • Liu, K.1    Victora, G.D.2    Schwickert, T.A.3
  • 33
    • 0036237312 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis induction in naive mice by dendritic cells presenting a self-peptide
    • COI: 1:CAS:528:DC%2BD38XitVWgtbg%3D, PID: 11869358
    • Weir CR, Nicolson K, Bäckström BT (2002) Experimental autoimmune encephalomyelitis induction in naive mice by dendritic cells presenting a self-peptide. Immunol Cell Biol 80:14–20. doi:10.1046/j.1440-1711.2002.01056.x
    • (2002) Immunol Cell Biol , vol.80 , pp. 14-20
    • Weir, C.R.1    Nicolson, K.2    Bäckström, B.T.3
  • 34
    • 77952310536 scopus 로고    scopus 로고
    • GM-CSF-dependent, CD103+ dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization
    • COI: 1:CAS:528:DC%2BC3cXmtFentL0%3D, PID: 20421390
    • King IL, Kroenke MA, Segal BM (2010) GM-CSF-dependent, CD103+ dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization. J Exp Med 207:953–961. doi:10.1084/jem.20091844
    • (2010) J Exp Med , vol.207 , pp. 953-961
    • King, I.L.1    Kroenke, M.A.2    Segal, B.M.3
  • 35
    • 80054754519 scopus 로고    scopus 로고
    • Batf3-dependent CD11b(low/−) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization
    • COI: 1:CAS:528:DC%2BC3MXhsVCku73O, PID: 22065991
    • Edelson BT, Bradstreet TR, Wumesh KC et al (2011) Batf3-dependent CD11b(low/−) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization. PLoS One 6:e25660. doi:10.1371/journal.pone.0025660.s001
    • (2011) PLoS One , vol.6
    • Edelson, B.T.1    Bradstreet, T.R.2    Wumesh, K.C.3
  • 36
    • 84896522891 scopus 로고    scopus 로고
    • GM-CSF-responsive monocyte-derived dendritic cells are pivotal in Th17 pathogenesis
    • COI: 1:CAS:528:DC%2BC2cXivFOru7Y%3D, PID: 24489100
    • Ko H-J, Brady JL, Ryg-Cornejo V et al (2014) GM-CSF-responsive monocyte-derived dendritic cells are pivotal in Th17 pathogenesis. J Immunol 192:2202–2209. doi:10.4049/jimmunol.1302040
    • (2014) J Immunol , vol.192 , pp. 2202-2209
    • Ko, H.-J.1    Brady, J.L.2    Ryg-Cornejo, V.3
  • 37
    • 84942516683 scopus 로고    scopus 로고
    • GM-CSF in neuroinflammation: licensing myeloid cells for tissue damage
    • COI: 1:CAS:528:DC%2BC2MXhsF2kur%2FM, PID: 26431942
    • Croxford AL, Spath S, Becher B (2015) GM-CSF in neuroinflammation: licensing myeloid cells for tissue damage. Trends Immunol 36:651–662. doi:10.1016/j.it.2015.08.004
    • (2015) Trends Immunol , vol.36 , pp. 651-662
    • Croxford, A.L.1    Spath, S.2    Becher, B.3
  • 38
    • 84965188468 scopus 로고
    • Time of appearance of antibodies to brain in the human receiving anti-rabies vaccine
    • COI: 1:STN:280:DyaH1M%2FltFSltg%3D%3D
    • Kirk RC, Ecker EE (1949) Time of appearance of antibodies to brain in the human receiving anti-rabies vaccine. Exp Biol Med 70:734–737. doi:10.3181/00379727-70-17051
    • (1949) Exp Biol Med , vol.70 , pp. 734-737
    • Kirk, R.C.1    Ecker, E.E.2
  • 39
    • 4043144986 scopus 로고    scopus 로고
    • Initiation of immune responses in brain is promoted by local dendritic cells
    • COI: 1:CAS:528:DC%2BD2cXmt1Ols7o%3D, PID: 15294948
    • Karman J, Ling C, Sandor M, Fabry Z (2004) Initiation of immune responses in brain is promoted by local dendritic cells. J Immunol 173:2353–2361. doi:10.4049/jimmunol.173.4.2353
    • (2004) J Immunol , vol.173 , pp. 2353-2361
    • Karman, J.1    Ling, C.2    Sandor, M.3    Fabry, Z.4
  • 40
    • 81855167104 scopus 로고    scopus 로고
    • Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
    • COI: 1:CAS:528:DC%2BC3MXhtlOntbbP, PID: 22031325
    • Berer K, Mues M, Koutrolos M et al (2011) Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature 479:538–541. doi:10.1038/nature10554
    • (2011) Nature , vol.479 , pp. 538-541
    • Berer, K.1    Mues, M.2    Koutrolos, M.3
  • 41
    • 62849102106 scopus 로고    scopus 로고
    • Surgical excision of CNS-draining lymph nodes reduces relapse severity in chronic-relapsing experimental autoimmune encephalomyelitis
    • PID: 19023878
    • Van Zwam M, Huizinga R, Heijmans N et al (2009) Surgical excision of CNS-draining lymph nodes reduces relapse severity in chronic-relapsing experimental autoimmune encephalomyelitis. J Pathol 217:543–551. doi:10.1002/path.2476
    • (2009) J Pathol , vol.217 , pp. 543-551
    • Van Zwam, M.1    Huizinga, R.2    Heijmans, N.3
  • 42
    • 58149294030 scopus 로고    scopus 로고
    • Swift entry of myelin-specific T lymphocytes into the central nervous system in spontaneous autoimmune encephalomyelitis
    • COI: 1:CAS:528:DC%2BD1cXhtFarurzP, PID: 18802067
    • Furtado GC, Marcondes MCG, Latkowski J-A et al (2008) Swift entry of myelin-specific T lymphocytes into the central nervous system in spontaneous autoimmune encephalomyelitis. J Immunol 181:4648–4655
    • (2008) J Immunol , vol.181 , pp. 4648-4655
    • Furtado, G.C.1    Marcondes, M.C.G.2    Latkowski, J.-A.3
  • 43
    • 84865391725 scopus 로고    scopus 로고
    • Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor(+) regulatory T cells
    • COI: 1:CAS:528:DC%2BC38Xht1WrtL%2FF, PID: 22902234
    • Yogev N, Frommer F, Lukas D et al (2012) Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor(+) regulatory T cells. Immunity 37:264–275. doi:10.1016/j.immuni.2012.05.025
    • (2012) Immunity , vol.37 , pp. 264-275
    • Yogev, N.1    Frommer, F.2    Lukas, D.3
  • 44
    • 60549104213 scopus 로고    scopus 로고
    • Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE
    • COI: 1:CAS:528:DC%2BD1MXitVOrt7g%3D, PID: 19050840
    • Van Zwam M, Huizinga R, Melief M-J et al (2009) Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE. J Mol Med 87:273–286. doi:10.1007/s00109-008-0421-4
    • (2009) J Mol Med , vol.87 , pp. 273-286
    • Van Zwam, M.1    Huizinga, R.2    Melief, M.-J.3
  • 45
    • 18644375874 scopus 로고    scopus 로고
    • In vivo depletion of CD11c + dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens
    • COI: 1:CAS:528:DC%2BD38Xms12jsr8%3D, PID: 12196292
    • Jung S, Unutmaz D, Wong P et al (2002) In vivo depletion of CD11c + dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity 17:211–220
    • (2002) Immunity , vol.17 , pp. 211-220
    • Jung, S.1    Unutmaz, D.2    Wong, P.3
  • 46
    • 84867191763 scopus 로고    scopus 로고
    • Conditional DC depletion does not affect priming of encephalitogenic Th cells in EAE
    • COI: 1:CAS:528:DC%2BC38XhtFKlsbjI, PID: 22806332
    • Isaksson M, Lundgren BA, Ahlgren KM et al (2012) Conditional DC depletion does not affect priming of encephalitogenic Th cells in EAE. Eur J Immunol 42:2555–2563. doi:10.1002/eji.201142239
    • (2012) Eur J Immunol , vol.42 , pp. 2555-2563
    • Isaksson, M.1    Lundgren, B.A.2    Ahlgren, K.M.3
  • 47
    • 84994469312 scopus 로고    scopus 로고
    • Dendritic cells tip the balance towards induction of regulatory T cells upon priming in experimental autoimmune encephalomyelitis
    • PID: 27707650
    • Paterka M, Voss JO, Werr J et al (2016) Dendritic cells tip the balance towards induction of regulatory T cells upon priming in experimental autoimmune encephalomyelitis. J Autoimmun. doi:10.1016/j.jaut.2016.09.008
    • (2016) J Autoimmun
    • Paterka, M.1    Voss, J.O.2    Werr, J.3
  • 48
    • 22144444873 scopus 로고    scopus 로고
    • Heterogeneity of thymic dendritic cells
    • COI: 1:CAS:528:DC%2BD2MXmsVWktLk%3D, PID: 15946853
    • Wu L, Shortman K (2005) Heterogeneity of thymic dendritic cells. Semin Immunol 17:304–312. doi:10.1016/j.smim.2005.05.001
    • (2005) Semin Immunol , vol.17 , pp. 304-312
    • Wu, L.1    Shortman, K.2
  • 49
    • 72949104779 scopus 로고    scopus 로고
    • Antigen presentation in the thymus for positive selection and central tolerance induction
    • COI: 1:CAS:528:DC%2BD1MXhsVOhurrM, PID: 19935803
    • Klein L, Hinterberger M, Wirnsberger G, Kyewski B (2009) Antigen presentation in the thymus for positive selection and central tolerance induction. Nat Rev Immunol 9:833–844. doi:10.1038/nri2669
    • (2009) Nat Rev Immunol , vol.9 , pp. 833-844
    • Klein, L.1    Hinterberger, M.2    Wirnsberger, G.3    Kyewski, B.4
  • 50
    • 70350539316 scopus 로고    scopus 로고
    • Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE
    • COI: 1:CAS:528:DC%2BD1MXht1amurbK, PID: 19637225
    • Isaksson M, Ardesjö B, Rönnblom L et al (2009) Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE. Eur J Immunol 39:2925–2935. doi:10.1002/eji.200839179
    • (2009) Eur J Immunol , vol.39 , pp. 2925-2935
    • Isaksson, M.1    Ardesjö, B.2    Rönnblom, L.3
  • 51
    • 77956098825 scopus 로고    scopus 로고
    • MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity
    • COI: 1:CAS:528:DC%2BC3cXhtFensr3K, PID: 20696698
    • Irla M, Küpfer N, Suter T et al (2010) MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity. J Exp Med 207:1891–1905. doi:10.1084/jem.20092627
    • (2010) J Exp Med , vol.207 , pp. 1891-1905
    • Irla, M.1    Küpfer, N.2    Suter, T.3
  • 52
    • 79959541655 scopus 로고    scopus 로고
    • Antigen delivery to plasmacytoid dendritic cells via BST2 induces protective T cell-mediated immunity
    • COI: 1:CAS:528:DC%2BC3MXntVGnt7w%3D, PID: 21555533
    • Loschko J, Schlitzer A, Dudziak D et al (2011) Antigen delivery to plasmacytoid dendritic cells via BST2 induces protective T cell-mediated immunity. J Immunol 186:6718–6725. doi:10.4049/jimmunol.1004029
    • (2011) J Immunol , vol.186 , pp. 6718-6725
    • Loschko, J.1    Schlitzer, A.2    Dudziak, D.3
  • 53
    • 2942523789 scopus 로고    scopus 로고
    • Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo
    • COI: 1:CAS:528:DC%2BD2cXltlKisLk%3D, PID: 15189735
    • Hawiger D, Masilamani RF, Bettelli E et al (2004) Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo. Immunity 20:695–705. doi:10.1016/j.immuni.2004.05.002
    • (2004) Immunity , vol.20 , pp. 695-705
    • Hawiger, D.1    Masilamani, R.F.2    Bettelli, E.3
  • 54
    • 0036715411 scopus 로고    scopus 로고
    • Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?
    • COI: 1:CAS:528:DC%2BD38XmsVekuro%3D, PID: 12200066
    • Lutz MB, Schuler G (2002) Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol 23:445–449
    • (2002) Trends Immunol , vol.23 , pp. 445-449
    • Lutz, M.B.1    Schuler, G.2
  • 55
    • 84886728752 scopus 로고    scopus 로고
    • IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39
    • COI: 1:CAS:528:DC%2BC3sXhtlGltL7I, PID: 23995234
    • Mascanfroni ID, Yeste A, Vieira SM et al (2013) IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. Nat Immunol 14:1054–1063. doi:10.1038/ni.2695
    • (2013) Nat Immunol , vol.14 , pp. 1054-1063
    • Mascanfroni, I.D.1    Yeste, A.2    Vieira, S.M.3
  • 56
    • 84975841205 scopus 로고    scopus 로고
    • Tolerogenic nanoparticles inhibit T cell-mediated autoimmunity through SOCS2
    • PID: 27330188
    • Yeste A, Takenaka MC, Mascanfroni ID et al (2016) Tolerogenic nanoparticles inhibit T cell-mediated autoimmunity through SOCS2. Sci Signal 9:ra61. doi:10.1126/scisignal.aad0612
    • (2016) Sci Signal , vol.9 , pp. ra61
    • Yeste, A.1    Takenaka, M.C.2    Mascanfroni, I.D.3
  • 58
    • 33845628839 scopus 로고    scopus 로고
    • What is immune privilege (not)?
    • COI: 1:CAS:528:DC%2BD2sXhsFCjsA%3D%3D, PID: 17129764
    • Galea I, Bechmann I, Perry VH (2007) What is immune privilege (not)? Trends Immunol 28:12–18. doi:10.1016/j.it.2006.11.004
    • (2007) Trends Immunol , vol.28 , pp. 12-18
    • Galea, I.1    Bechmann, I.2    Perry, V.H.3
  • 59
    • 84983048399 scopus 로고    scopus 로고
    • Multifaceted interactions between adaptive immunity and the central nervous system
    • COI: 1:CAS:528:DC%2BC28XhtlCju73O
    • Kipnis J (2016) Multifaceted interactions between adaptive immunity and the central nervous system. Science (New York, NY) 353:766–771. doi:10.1126/science.aag2638
    • (2016) Science (New York, NY) , vol.353 , pp. 766-771
    • Kipnis, J.1
  • 60
    • 84982121622 scopus 로고    scopus 로고
    • Vascular, glial, and lymphatic immune gateways of the central nervous system
    • COI: 1:CAS:528:DC%2BC28XhtlyjsrvI, PID: 27522506
    • Engelhardt B, Carare RO, Bechmann I et al (2016) Vascular, glial, and lymphatic immune gateways of the central nervous system. Acta Neuropathol 132:317–338. doi:10.1007/s00401-016-1606-5
    • (2016) Acta Neuropathol , vol.132 , pp. 317-338
    • Engelhardt, B.1    Carare, R.O.2    Bechmann, I.3
  • 61
    • 84885775321 scopus 로고    scopus 로고
    • Sleep drives metabolite clearance from the adult brain
    • COI: 1:CAS:528:DC%2BC3sXhs1WltrnN
    • Xie L, Kang H, Xu Q et al (2013) Sleep drives metabolite clearance from the adult brain. Science (New York, NY) 342:373–377. doi:10.1126/science.1241224
    • (2013) Science (New York, NY) , vol.342 , pp. 373-377
    • Xie, L.1    Kang, H.2    Xu, Q.3
  • 62
    • 84865123660 scopus 로고    scopus 로고
    • A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β
    • PID: 22896675
    • Iliff JJ, Wang M, Liao Y et al (2012) A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β. Sci Transl Med 4:147ra111. doi:10.1126/scitranslmed.3003748
    • (2012) Sci Transl Med , vol.4 , pp. 147ra111
    • Iliff, J.J.1    Wang, M.2    Liao, Y.3
  • 63
    • 77954865385 scopus 로고    scopus 로고
    • The function and structure of the cerebrospinal fluid outflow system
    • PID: 20565964
    • Pollay M (2010) The function and structure of the cerebrospinal fluid outflow system. Cerebrospinal Fluid Res 7:9. doi:10.1186/1743-8454-7-9
    • (2010) Cerebrospinal Fluid Res , vol.7 , pp. 9
    • Pollay, M.1
  • 64
    • 0023925232 scopus 로고
    • Functional ultrastructure of cerebrospinal fluid drainage channels in human arachnoid villi
    • COI: 1:STN:280:DyaL1c3jtlajtQ%3D%3D, PID: 3374774
    • Yamashima T (1988) Functional ultrastructure of cerebrospinal fluid drainage channels in human arachnoid villi. Neurosurgery 22:633–641
    • (1988) Neurosurgery , vol.22 , pp. 633-641
    • Yamashima, T.1
  • 65
    • 0017091576 scopus 로고
    • Human spinal arachnoid villi and granulations
    • COI: 1:STN:280:DyaE2s%2FjsV2nsg%3D%3D, PID: 980235
    • Kido DK, Gomez DG, Pavese AM, Potts DG (1976) Human spinal arachnoid villi and granulations. Neuroradiology 11:221–228
    • (1976) Neuroradiology , vol.11 , pp. 221-228
    • Kido, D.K.1    Gomez, D.G.2    Pavese, A.M.3    Potts, D.G.4
  • 66
    • 0022405306 scopus 로고
    • The morphology of cerebrospinal fluid drainage pathways in human arachnoid granulations
    • COI: 1:STN:280:DyaL28%2Fjs1Clsw%3D%3D, PID: 4056901
    • Upton ML, Weller RO (1985) The morphology of cerebrospinal fluid drainage pathways in human arachnoid granulations. J Neurosurg 63:867–875. doi:10.3171/jns.1985.63.6.0867
    • (1985) J Neurosurg , vol.63 , pp. 867-875
    • Upton, M.L.1    Weller, R.O.2
  • 67
    • 0027740941 scopus 로고
    • CSF drains directly from the subarachnoid space into nasal lymphatics in the rat. Anatomy, histology and immunological significance
    • COI: 1:STN:280:DyaK2c7ms12gug%3D%3D, PID: 7510047
    • Kida S, Kida S, Pentazis A et al (1993) CSF drains directly from the subarachnoid space into nasal lymphatics in the rat. Anatomy, histology and immunological significance. Neuropathol Appl Neurobiol 19:480–488. doi:10.1111/j.1365-2990.1993.tb00476.x
    • (1993) Neuropathol Appl Neurobiol , vol.19 , pp. 480-488
    • Kida, S.1    Kida, S.2    Pentazis, A.3
  • 68
    • 33749414503 scopus 로고    scopus 로고
    • Evidence of connections between cerebrospinal fluid and nasal lymphatic vessels in humans, non-human primates and other mammalian species
    • PID: 15679948
    • Johnston M, Zakharov A, Papaiconomou C et al (2004) Evidence of connections between cerebrospinal fluid and nasal lymphatic vessels in humans, non-human primates and other mammalian species. Cerebrospinal Fluid Res 1:2. doi:10.1186/1743-8454-1-2
    • (2004) Cerebrospinal Fluid Res , vol.1 , pp. 2
    • Johnston, M.1    Zakharov, A.2    Papaiconomou, C.3
  • 69
    • 0023182521 scopus 로고
    • Nerve fibres and their terminals of the dura mater encephali of the rat
    • COI: 1:STN:280:DyaL2s7lsVersA%3D%3D, PID: 3826655
    • Andres KH, Düring von M, Muszynski K, Schmidt RF (1987) Nerve fibres and their terminals of the dura mater encephali of the rat. Anat Embryol 175:289–301
    • (1987) Anat Embryol , vol.175 , pp. 289-301
    • Andres, K.H.1    Düring von, M.2    Muszynski, K.3    Schmidt, R.F.4
  • 70
    • 84936871460 scopus 로고    scopus 로고
    • Structural and functional features of central nervous system lymphatic vessels
    • COI: 1:CAS:528:DC%2BC2MXhtFaitrrE, PID: 26030524
    • Louveau A, Smirnov I, Keyes TJ et al (2015) Structural and functional features of central nervous system lymphatic vessels. Nature 523:337–341. doi:10.1038/nature14432
    • (2015) Nature , vol.523 , pp. 337-341
    • Louveau, A.1    Smirnov, I.2    Keyes, T.J.3
  • 71
    • 84942469639 scopus 로고    scopus 로고
    • A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules
    • COI: 1:CAS:528:DC%2BC2MXhtFygtLjL, PID: 26077718
    • Aspelund A, Aspelund A, Antila S et al (2015) A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. J Exp Med 212:991–999. doi:10.1084/jem.20142290
    • (2015) J Exp Med , vol.212 , pp. 991-999
    • Aspelund, A.1    Aspelund, A.2    Antila, S.3
  • 72
    • 59649113879 scopus 로고    scopus 로고
    • Topographic study on nerve-associated lymphatic vessels in the murine craniofacial region by immunohistochemistry and electron microscopy
    • COI: 1:CAS:528:DC%2BD1MXis1aitg%3D%3D, PID: 19129672
    • Furukawa M, Shimoda H, Kajiwara T et al (2008) Topographic study on nerve-associated lymphatic vessels in the murine craniofacial region by immunohistochemistry and electron microscopy. Biomed Res 29:289–296
    • (2008) Biomed Res , vol.29 , pp. 289-296
    • Furukawa, M.1    Shimoda, H.2    Kajiwara, T.3
  • 73
    • 1842409528 scopus 로고    scopus 로고
    • Dynamic properties of lymphatic pathways for the absorption of cerebrospinal fluid
    • COI: 1:STN:280:DyaK1c%2FkvVSitg%3D%3D, PID: 9386783
    • Brinker T, Lüdemann W, Berens von Rautenfeld D, Samii M (1997) Dynamic properties of lymphatic pathways for the absorption of cerebrospinal fluid. Acta Neuropathol 94:493–498
    • (1997) Acta Neuropathol , vol.94 , pp. 493-498
    • Brinker, T.1    Lüdemann, W.2    Berens von Rautenfeld, D.3    Samii, M.4
  • 74
    • 84863495639 scopus 로고    scopus 로고
    • Migration of monocytes after intracerebral injection at entorhinal cortex lesion site
    • COI: 1:CAS:528:DC%2BC38XhtVOrsbzP, PID: 22291210
    • Kaminski M, Bechmann I, Pohland M et al (2012) Migration of monocytes after intracerebral injection at entorhinal cortex lesion site. J Leukoc Biol 92:31–39. doi:10.1189/jlb.0511241
    • (2012) J Leukoc Biol , vol.92 , pp. 31-39
    • Kaminski, M.1    Bechmann, I.2    Pohland, M.3
  • 75
    • 84896752215 scopus 로고    scopus 로고
    • Immune cell trafficking from the brain maintains CNS immune tolerance
    • COI: 1:CAS:528:DC%2BC2cXkt1Wrt70%3D, PID: 24569378
    • Mohammad MG, Tsai VWW, Ruitenberg MJ et al (2014) Immune cell trafficking from the brain maintains CNS immune tolerance. J Clin Invest 124:1228–1241. doi:10.1172/JCI71544
    • (2014) J Clin Invest , vol.124 , pp. 1228-1241
    • Mohammad, M.G.1    Tsai, V.W.W.2    Ruitenberg, M.J.3
  • 76
    • 84963841577 scopus 로고    scopus 로고
    • Origin, fate and dynamics of macrophages at central nervous system interfaces
    • COI: 1:CAS:528:DC%2BC28XmvFOqsbk%3D, PID: 27135602
    • Goldmann T, Wieghofer P, Jordão MJC et al (2016) Origin, fate and dynamics of macrophages at central nervous system interfaces. Nat Immunol 17:797–805. doi:10.1038/ni.3423
    • (2016) Nat Immunol , vol.17 , pp. 797-805
    • Goldmann, T.1    Wieghofer, P.2    Jordão, M.J.C.3
  • 77
    • 79953675959 scopus 로고    scopus 로고
    • CD11c-expressing cells reside in the juxtavascular parenchyma and extend processes into the glia limitans of the mouse nervous system
    • COI: 1:CAS:528:DC%2BC3MXjsVWmtbs%3D, PID: 21076838
    • Prodinger C, Bunse J, Krüger M et al (2011) CD11c-expressing cells reside in the juxtavascular parenchyma and extend processes into the glia limitans of the mouse nervous system. Acta Neuropathol 121:445–458. doi:10.1007/s00401-010-0774-y
    • (2011) Acta Neuropathol , vol.121 , pp. 445-458
    • Prodinger, C.1    Bunse, J.2    Krüger, M.3
  • 78
    • 43749110906 scopus 로고    scopus 로고
    • CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain
    • PID: 18386786
    • Bulloch K, Miller MM, Gal-Toth J et al (2008) CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain. J Comp Neurol 508:687–710. doi:10.1002/cne.21668
    • (2008) J Comp Neurol , vol.508 , pp. 687-710
    • Bulloch, K.1    Miller, M.M.2    Gal-Toth, J.3
  • 79
    • 79961160742 scopus 로고    scopus 로고
    • Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
    • COI: 1:CAS:528:DC%2BC3MXhtVSit7rI, PID: 21788405
    • Anandasabapathy N, Victora GD, Meredith M et al (2011) Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain. J Exp Med 208:1695–1705. doi:10.1084/jem.20102657
    • (2011) J Exp Med , vol.208 , pp. 1695-1705
    • Anandasabapathy, N.1    Victora, G.D.2    Meredith, M.3
  • 80
    • 84875553508 scopus 로고    scopus 로고
    • Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus
    • COI: 1:CAS:528:DC%2BC3sXjvVegtrk%3D, PID: 23477737
    • Shechter R, Miller O, Yovel G et al (2013) Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus. Immunity 38:555–569. doi:10.1016/j.immuni.2013.02.012
    • (2013) Immunity , vol.38 , pp. 555-569
    • Shechter, R.1    Miller, O.2    Yovel, G.3
  • 81
    • 61449227381 scopus 로고    scopus 로고
    • Decrease in the numbers of dendritic cells and CD4+ T cells in cerebral perivascular spaces due to natalizumab
    • del Pilar MM, Cravens PD, Winger R et al (2008) Decrease in the numbers of dendritic cells and CD4+ T cells in cerebral perivascular spaces due to natalizumab. Arch Neurol 65:1596–1603. doi:10.1001/archneur.65.12.noc80051
    • (2008) Arch Neurol , vol.65 , pp. 1596-1603
    • del Pilar, M.M.1    Cravens, P.D.2    Winger, R.3
  • 82
    • 0036270888 scopus 로고    scopus 로고
    • Interferon-beta directly influences monocyte infiltration into the central nervous system
    • COI: 1:CAS:528:DC%2BD38XktFKisrs%3D, PID: 12044977
    • Floris S, Ruuls SR, Wierinckx A et al (2002) Interferon-beta directly influences monocyte infiltration into the central nervous system. J Neuroimmunol 127:69–79. doi:10.1016/S0165-5728(02)00098-X
    • (2002) J Neuroimmunol , vol.127 , pp. 69-79
    • Floris, S.1    Ruuls, S.R.2    Wierinckx, A.3
  • 83
    • 77953642555 scopus 로고    scopus 로고
    • Alpha4beta1 integrin mediates the recruitment of immature dendritic cells across the blood-brain barrier during experimental autoimmune encephalomyelitis
    • COI: 1:CAS:528:DC%2BC3cXmvFejtrY%3D, PID: 20483748
    • Jain P, Coisne C, Enzmann G et al (2010) Alpha4beta1 integrin mediates the recruitment of immature dendritic cells across the blood-brain barrier during experimental autoimmune encephalomyelitis. J Immunol 184:7196–7206. doi:10.4049/jimmunol.0901404
    • (2010) J Immunol , vol.184 , pp. 7196-7206
    • Jain, P.1    Coisne, C.2    Enzmann, G.3
  • 84
    • 0026506799 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin
    • COI: 1:CAS:528:DyaK38Xhslaisbw%3D, PID: 1538783
    • Yednock TA, Cannon C, Fritz LC et al (1992) Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature 356:63–66. doi:10.1038/356063a0
    • (1992) Nature , vol.356 , pp. 63-66
    • Yednock, T.A.1    Cannon, C.2    Fritz, L.C.3
  • 85
    • 84855475637 scopus 로고    scopus 로고
    • Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE
    • COI: 1:CAS:528:DC%2BC3MXhsFOhsbfI, PID: 22025301
    • Rothhammer V, Heink S, Petermann F et al (2011) Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE. J Exp Med 208:2465–2476. doi:10.1084/jem.20110434
    • (2011) J Exp Med , vol.208 , pp. 2465-2476
    • Rothhammer, V.1    Heink, S.2    Petermann, F.3
  • 86
    • 83755184226 scopus 로고    scopus 로고
    • Cutting edge: loss of α4 integrin expression differentially affects the homing of Th1 and Th17 cells
    • COI: 1:CAS:528:DC%2BC3MXhsFOgt7%2FE, PID: 22084440
    • Glatigny S, Duhen R, Oukka M, Bettelli E (2011) Cutting edge: loss of α4 integrin expression differentially affects the homing of Th1 and Th17 cells. J Immunol 187:6176–6179. doi:10.4049/jimmunol.1102515
    • (2011) J Immunol , vol.187 , pp. 6176-6179
    • Glatigny, S.1    Duhen, R.2    Oukka, M.3    Bettelli, E.4
  • 87
    • 33644584352 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis
    • COI: 1:CAS:528:DC%2BD28XitVertL4%3D, PID: 16510744
    • Polman CH, O'connor PW, Havrdova E et al (2006) A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med 354:899–910. doi:10.1056/NEJMoa044397
    • (2006) N Engl J Med , vol.354 , pp. 899-910
    • Polman, C.H.1    O'connor, P.W.2    Havrdova, E.3
  • 88
    • 0023949553 scopus 로고
    • Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo
    • COI: 1:STN:280:DyaL1c%2FpvFGisw%3D%3D
    • Hickey WF, Kimura H (1988) Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. Science (New York, NY) 239:290–292
    • (1988) Science (New York, NY) , vol.239 , pp. 290-292
    • Hickey, W.F.1    Kimura, H.2
  • 89
    • 16244380177 scopus 로고    scopus 로고
    • Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
    • COI: 1:CAS:528:DC%2BD2MXhvVSqsr4%3D, PID: 15735653
    • Greter M, Heppner FL, Lemos MP et al (2005) Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis. Nat Med 11:328–334. doi:10.1038/nm1197
    • (2005) Nat Med , vol.11 , pp. 328-334
    • Greter, M.1    Heppner, F.L.2    Lemos, M.P.3
  • 90
    • 77952982377 scopus 로고    scopus 로고
    • Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation
    • PID: 20424288
    • Hesske L, Vincenzetti C, Heikenwalder M et al (2010) Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation. Brain 133:1637–1654. doi:10.1093/brain/awq081
    • (2010) Brain , vol.133 , pp. 1637-1654
    • Hesske, L.1    Vincenzetti, C.2    Heikenwalder, M.3
  • 91
    • 70449106029 scopus 로고    scopus 로고
    • Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions
    • PID: 19829296
    • Bartholomäus I, Kawakami N, Odoardi F et al (2009) Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions. Nature 462:94–98. doi:10.1038/nature08478
    • (2009) Nature , vol.462 , pp. 94-98
    • Bartholomäus, I.1    Kawakami, N.2    Odoardi, F.3
  • 92
    • 84959020187 scopus 로고    scopus 로고
    • Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid
    • PID: 26863192
    • Schläger C, Körner H, Krueger M et al (2016) Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid. Nature 530:349–353. doi:10.1038/nature16939
    • (2016) Nature , vol.530 , pp. 349-353
    • Schläger, C.1    Körner, H.2    Krueger, M.3
  • 93
    • 16244417773 scopus 로고    scopus 로고
    • Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
    • COI: 1:CAS:528:DC%2BD2MXhvVSqsrs%3D, PID: 15735651
    • Mcmahon EJ, Bailey SL, Castenada CV et al (2005) Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis. Nat Med 11:335–339. doi:10.1038/nm1202
    • (2005) Nat Med , vol.11 , pp. 335-339
    • Mcmahon, E.J.1    Bailey, S.L.2    Castenada, C.V.3
  • 94
    • 33846472053 scopus 로고    scopus 로고
    • CNS myeloid DCs presenting endogenous myelin peptides “preferentially” polarize CD4+ T(H)-17 cells in relapsing EAE
    • COI: 1:CAS:528:DC%2BD2sXnt1KitQ%3D%3D, PID: 17206145
    • Bailey SL, Schreiner B, Mcmahon EJ, Miller SD (2007) CNS myeloid DCs presenting endogenous myelin peptides “preferentially” polarize CD4+ T(H)-17 cells in relapsing EAE. Nat Immunol 8:172–180. doi:10.1038/ni1430
    • (2007) Nat Immunol , vol.8 , pp. 172-180
    • Bailey, S.L.1    Schreiner, B.2    Mcmahon, E.J.3    Miller, S.D.4
  • 95
    • 39749173780 scopus 로고    scopus 로고
    • The blood-brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells
    • PID: 18156156
    • Ifergan I, Kebir H, Bernard M et al (2008) The blood-brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells. Brain 131:785–799. doi:10.1093/brain/awm295
    • (2008) Brain , vol.131 , pp. 785-799
    • Ifergan, I.1    Kebir, H.2    Bernard, M.3
  • 96
    • 65149093082 scopus 로고    scopus 로고
    • Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease
    • COI: 1:CAS:528:DC%2BD1MXksFWqsLY%3D, PID: 19196868
    • King IL, Dickendesher TL, Segal BM (2009) Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease. Blood 113:3190–3197. doi:10.1182/blood-2008-07-168575
    • (2009) Blood , vol.113 , pp. 3190-3197
    • King, I.L.1    Dickendesher, T.L.2    Segal, B.M.3
  • 97
    • 71549167047 scopus 로고    scopus 로고
    • CCR2 + Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system
    • PID: 19531531
    • Mildner A, Mack M, Schmidt H et al (2009) CCR2 + Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system. Brain 132:2487–2500. doi:10.1093/brain/awp144
    • (2009) Brain , vol.132 , pp. 2487-2500
    • Mildner, A.1    Mack, M.2    Schmidt, H.3
  • 98
    • 78149438403 scopus 로고    scopus 로고
    • Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice
    • PID: 21060874
    • Saederup N, Cardona AE, Croft K et al (2010) Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice. PLoS One 5:e13693. doi:10.1371/journal.pone.0013693
    • (2010) PLoS One , vol.5
    • Saederup, N.1    Cardona, A.E.2    Croft, K.3
  • 99
    • 84905116959 scopus 로고    scopus 로고
    • Differential roles of microglia and monocytes in the inflamed central nervous system
    • COI: 1:CAS:528:DC%2BC2cXht1KrtrnL, PID: 25002752
    • Yamasaki R, Lu H, Butovsky O et al (2014) Differential roles of microglia and monocytes in the inflamed central nervous system. J Exp Med 211:1533–1549. doi:10.1084/jem.20132477
    • (2014) J Exp Med , vol.211 , pp. 1533-1549
    • Yamasaki, R.1    Lu, H.2    Butovsky, O.3
  • 100
    • 72649106903 scopus 로고    scopus 로고
    • A type I interferon signature in monocytes is associated with poor response to interferon-beta in multiple sclerosis
    • COI: 1:STN:280:DC%2BD1Mfhs1Kmug%3D%3D, PID: 19741051
    • Comabella M, Lunemann JD, Rio J et al (2009) A type I interferon signature in monocytes is associated with poor response to interferon-beta in multiple sclerosis. Brain 132:3353–3365. doi:10.1093/brain/awp228
    • (2009) Brain , vol.132 , pp. 3353-3365
    • Comabella, M.1    Lunemann, J.D.2    Rio, J.3
  • 101
    • 0032080850 scopus 로고    scopus 로고
    • Type I IFNs inhibit human dendritic cell IL-12 production and Th1 cell development
    • COI: 1:CAS:528:DyaK1cXjtVCnu74%3D, PID: 9574532
    • McRae BL, Semnani RT, Hayes MP, Van Seventer GA (1998) Type I IFNs inhibit human dendritic cell IL-12 production and Th1 cell development. J Immunol 160:4298–4304
    • (1998) J Immunol , vol.160 , pp. 4298-4304
    • McRae, B.L.1    Semnani, R.T.2    Hayes, M.P.3    Van Seventer, G.A.4
  • 102
    • 0034954034 scopus 로고    scopus 로고
    • Interferons alpha and beta as immune regulators—a new look
    • COI: 1:CAS:528:DC%2BD3MXkvFSltr0%3D, PID: 11420036
    • Biron CA (2001) Interferons alpha and beta as immune regulators—a new look. Immunity 14:661–664
    • (2001) Immunity , vol.14 , pp. 661-664
    • Biron, C.A.1
  • 103
    • 33846871508 scopus 로고    scopus 로고
    • Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-alpha/beta on antigen cross-presentation
    • COI: 1:CAS:528:DC%2BD2sXjtFert7k%3D, PID: 17018853
    • Longman RS, Braun D, Pellegrini S et al (2007) Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-alpha/beta on antigen cross-presentation. Blood 109:1113–1122. doi:10.1182/blood-2006-05-023465
    • (2007) Blood , vol.109 , pp. 1113-1122
    • Longman, R.S.1    Braun, D.2    Pellegrini, S.3
  • 104
    • 0034944385 scopus 로고    scopus 로고
    • Type I interferons and IL-12: convergence and cross-regulation among mediators of cellular immunity
    • COI: 1:CAS:528:DC%2BD3MXlsVCltro%3D, PID: 11449355
    • Byrnes AA, Ma X, Cuomo P et al (2001) Type I interferons and IL-12: convergence and cross-regulation among mediators of cellular immunity. Eur J Immunol 31:2026–2034. doi:10.1002/1521-4141(200107)31:760;2026::AID-IMMU202662;3.0.CO;2-U
    • (2001) Eur J Immunol , vol.31 , pp. 2026-2034
    • Byrnes, A.A.1    Ma, X.2    Cuomo, P.3
  • 105
    • 84946088757 scopus 로고    scopus 로고
    • Differential effects of IFN-β on IL-12, IL-23, and IL-10 expression in TLR-stimulated dendritic cells
    • COI: 1:CAS:528:DC%2BC28XksVems74%3D, PID: 26059829
    • Yen J-H, Kong W, Hooper KM et al (2015) Differential effects of IFN-β on IL-12, IL-23, and IL-10 expression in TLR-stimulated dendritic cells. J Leukoc Biol 98:689–702. doi:10.1189/jlb.3HI0914-453R
    • (2015) J Leukoc Biol , vol.98 , pp. 689-702
    • Yen, J.-H.1    Kong, W.2    Hooper, K.M.3
  • 106
    • 0026094306 scopus 로고
    • Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes
    • De Waal MR, Abrams J, Bennett B et al (1991) Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 174:1209–1220
    • (1991) J Exp Med , vol.174 , pp. 1209-1220
    • De Waal, M.R.1    Abrams, J.2    Bennett, B.3
  • 107
    • 0029962451 scopus 로고    scopus 로고
    • Negative feedback mechanism suppresses interleukin-12 production by antigen-presenting cells interacting with T helper 2 cells
    • COI: 1:CAS:528:DyaK28XhvVGnt7k%3D, PID: 8605930
    • Hino A, Nariuchi H (1996) Negative feedback mechanism suppresses interleukin-12 production by antigen-presenting cells interacting with T helper 2 cells. Eur J Immunol 26:623–628. doi:10.1002/eji.1830260318
    • (1996) Eur J Immunol , vol.26 , pp. 623-628
    • Hino, A.1    Nariuchi, H.2
  • 108
    • 84865772924 scopus 로고    scopus 로고
    • Type I and III interferons enhance IL-10R expression on human monocytes and macrophages, resulting in IL-10-mediated suppression of TLR-induced IL-12
    • COI: 1:CAS:528:DC%2BC38XhtVWhu7%2FO, PID: 22685028
    • Liu B-S, Janssen HLA, Boonstra A (2012) Type I and III interferons enhance IL-10R expression on human monocytes and macrophages, resulting in IL-10-mediated suppression of TLR-induced IL-12. Eur J Immunol 42:2431–2440. doi:10.1002/eji.201142360
    • (2012) Eur J Immunol , vol.42 , pp. 2431-2440
    • Liu, B.-S.1    Janssen, H.L.A.2    Boonstra, A.3
  • 109
    • 77951634161 scopus 로고    scopus 로고
    • IFN-beta inhibits dendritic cell migration through STAT-1-mediated transcriptional suppression of CCR7 and matrix metalloproteinase 9
    • COI: 1:CAS:528:DC%2BC3cXjs1Wrt7g%3D, PID: 20190134
    • Yen J-H, Kong W, Ganea D (2010) IFN-beta inhibits dendritic cell migration through STAT-1-mediated transcriptional suppression of CCR7 and matrix metalloproteinase 9. J Immunol 184:3478–3486. doi:10.4049/jimmunol.0902542
    • (2010) J Immunol , vol.184 , pp. 3478-3486
    • Yen, J.-H.1    Kong, W.2    Ganea, D.3
  • 110
    • 33646233989 scopus 로고    scopus 로고
    • Impaired maturation and altered regulatory function of plasmacytoid dendritic cells in multiple sclerosis
    • PID: 16513684
    • Stasiolek M, Bayas A, Kruse N et al (2006) Impaired maturation and altered regulatory function of plasmacytoid dendritic cells in multiple sclerosis. Brain 129:1293–1305. doi:10.1093/brain/awl043
    • (2006) Brain , vol.129 , pp. 1293-1305
    • Stasiolek, M.1    Bayas, A.2    Kruse, N.3
  • 111
    • 43249104826 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells in multiple sclerosis: intracerebral recruitment and impaired maturation in response to interferon-beta
    • COI: 1:CAS:528:DC%2BD1cXmsFehtbo%3D, PID: 18431257
    • Lande R, Gafa V, Serafini B et al (2008) Plasmacytoid dendritic cells in multiple sclerosis: intracerebral recruitment and impaired maturation in response to interferon-beta. J Neuropathol Exp Neurol 67:388–401. doi:10.1097/NEN.0b013e31816fc975
    • (2008) J Neuropathol Exp Neurol , vol.67 , pp. 388-401
    • Lande, R.1    Gafa, V.2    Serafini, B.3
  • 112
    • 34547699396 scopus 로고    scopus 로고
    • Type II monocytes modulate T cell-mediated central nervous system autoimmune disease
    • COI: 1:CAS:528:DC%2BD2sXos1Cjsbc%3D, PID: 17676050
    • Weber MS, Prodhomme T, Youssef S et al (2007) Type II monocytes modulate T cell-mediated central nervous system autoimmune disease. Nat Med 13:935–943. doi:10.1038/nm1620
    • (2007) Nat Med , vol.13 , pp. 935-943
    • Weber, M.S.1    Prodhomme, T.2    Youssef, S.3
  • 113
    • 84959496129 scopus 로고    scopus 로고
    • Cutaneous adverse events in multiple sclerosis patients treated with daclizumab
    • COI: 1:CAS:528:DC%2BC28XjslCksb8%3D, PID: 26843560
    • Cortese I, Ohayon J, Fenton K et al (2016) Cutaneous adverse events in multiple sclerosis patients treated with daclizumab. Neurology 86:847–855. doi:10.1212/WNL.0000000000002417
    • (2016) Neurology , vol.86 , pp. 847-855
    • Cortese, I.1    Ohayon, J.2    Fenton, K.3
  • 114
    • 79955700857 scopus 로고    scopus 로고
    • A role for interleukin-2 trans-presentation in dendritic cell-mediated T cell activation in humans, as revealed by daclizumab therapy
    • COI: 1:CAS:528:DC%2BC3MXlsVGlurg%3D, PID: 21532597
    • Wuest SC, Edwan JH, Martin JF et al (2011) A role for interleukin-2 trans-presentation in dendritic cell-mediated T cell activation in humans, as revealed by daclizumab therapy. Nat Med 17:604–609. doi:10.1038/nm.2365
    • (2011) Nat Med , vol.17 , pp. 604-609
    • Wuest, S.C.1    Edwan, J.H.2    Martin, J.F.3
  • 115
    • 64149087952 scopus 로고    scopus 로고
    • alpha4-integrin antagonism with natalizumab: effects and adverse effects
    • PID: 19300961
    • Stüve O, Gold R, Chan A et al (2008) alpha4-integrin antagonism with natalizumab: effects and adverse effects. J Neurol 255(Suppl 6):58–65. doi:10.1007/s00415-008-6011-0
    • (2008) J Neurol , vol.255 , pp. 58-65
    • Stüve, O.1    Gold, R.2    Chan, A.3
  • 116
    • 84906568560 scopus 로고    scopus 로고
    • VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells
    • COI: 1:CAS:528:DC%2BC2cXhsVKgt7rE, PID: 25135296
    • Schneider-Hohendorf T, Rossaint J, Mohan H et al (2014) VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells. J Exp Med 211:1833–1846. doi:10.1084/jem.20140540
    • (2014) J Exp Med , vol.211 , pp. 1833-1846
    • Schneider-Hohendorf, T.1    Rossaint, J.2    Mohan, H.3
  • 117
    • 33646347610 scopus 로고    scopus 로고
    • Immune surveillance in multiple sclerosis patients treated with natalizumab
    • PID: 16634029
    • Stüve O, Marra CM, Jerome KR et al (2006) Immune surveillance in multiple sclerosis patients treated with natalizumab. Ann Neurol 59:743–747. doi:10.1002/ana.20858
    • (2006) Ann Neurol , vol.59 , pp. 743-747
    • Stüve, O.1    Marra, C.M.2    Jerome, K.R.3
  • 118
    • 34447275920 scopus 로고    scopus 로고
    • Notch-RBP-J signaling controls the homeostasis of CD8-dendritic cells in the spleen
    • COI: 1:CAS:528:DC%2BD2sXnslyls78%3D, PID: 17591855
    • Caton ML, Smith-Raska MR, Reizis B (2007) Notch-RBP-J signaling controls the homeostasis of CD8-dendritic cells in the spleen. J Exp Med 204:1653–1664. doi:10.1084/jem.20062648
    • (2007) J Exp Med , vol.204 , pp. 1653-1664
    • Caton, M.L.1    Smith-Raska, M.R.2    Reizis, B.3
  • 119
    • 84903516068 scopus 로고    scopus 로고
    • Comparative analysis of the efficiency and specificity of myeloid-cre deleting strains using ROSA-EYFP reporter mice
    • COI: 1:CAS:528:DC%2BC2cXpslahs7c%3D, PID: 24857755
    • Abram CL, Roberge GL, Hu Y, Lowell CA (2014) Comparative analysis of the efficiency and specificity of myeloid-cre deleting strains using ROSA-EYFP reporter mice. J Immunol Methods 408:89–100. doi:10.1016/j.jim.2014.05.009
    • (2014) J Immunol Methods , vol.408 , pp. 89-100
    • Abram, C.L.1    Roberge, G.L.2    Hu, Y.3    Lowell, C.A.4
  • 120
    • 82755190623 scopus 로고    scopus 로고
    • Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells
    • COI: 1:CAS:528:DC%2BC3MXhs1eitLfJ, PID: 22084093
    • Baschant U, Frappart L, Rauchhaus U et al (2011) Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells. Proc Natl Acad Sci U S A 108:19317–19322. doi:10.1073/pnas.1105857108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 19317-19322
    • Baschant, U.1    Frappart, L.2    Rauchhaus, U.3
  • 121
    • 34248577055 scopus 로고    scopus 로고
    • Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity
    • COI: 1:CAS:528:DC%2BD2sXmt1ajsL8%3D, PID: 17509906
    • Stranges PB, Watson J, Cooper CJ et al (2007) Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity. Immunity 26:629–641. doi:10.1016/j.immuni.2007.03.016
    • (2007) Immunity , vol.26 , pp. 629-641
    • Stranges, P.B.1    Watson, J.2    Cooper, C.J.3
  • 122
    • 63449108301 scopus 로고    scopus 로고
    • Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity
    • COI: 1:CAS:528:DC%2BD1MXjsVaisb8%3D, PID: 19237601
    • Ohnmacht C, Pullner A, King SBS et al (2009) Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. J Exp Med 206:549–559. doi:10.1084/jem.20082394
    • (2009) J Exp Med , vol.206 , pp. 549-559
    • Ohnmacht, C.1    Pullner, A.2    King, S.B.S.3
  • 123
    • 84963537474 scopus 로고    scopus 로고
    • Inducible targeting of cDCs and their subsets in vivo
    • COI: 1:CAS:528:DC%2BC28XmtFCiu7k%3D, PID: 27073171
    • Loschko J, Rieke GJ, Schreiber HA et al (2016) Inducible targeting of cDCs and their subsets in vivo. J Immunol Methods 434:32–38. doi:10.1016/j.jim.2016.04.004
    • (2016) J Immunol Methods , vol.434 , pp. 32-38
    • Loschko, J.1    Rieke, G.J.2    Schreiber, H.A.3
  • 124
    • 85011725843 scopus 로고    scopus 로고
    • Absence of MHC class II on cDCs results in microbialdependent intestinal in ammation
    • jem.20160062
    • Loschko J, Schreiber HA, Rieke GJ et al (2016) Absence of MHC class II on cDCs results in microbialdependent intestinal in ammation. J Exp Med. doi:10.4049/jimmunol.176.4.2465jem.20160062
    • (2016) J Exp Med
    • Loschko, J.1    Schreiber, H.A.2    Rieke, G.J.3
  • 125
    • 78650178928 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cell ablation impacts early interferon responses and antiviral NK and CD8(+) T cell accrual
    • COI: 1:CAS:528:DC%2BC3cXhsFyisLvO, PID: 21130004
    • Swiecki M, Gilfillan S, Vermi W et al (2010) Plasmacytoid dendritic cell ablation impacts early interferon responses and antiviral NK and CD8(+) T cell accrual. Immunity 33:955–966. doi:10.1016/j.immuni.2010.11.020
    • (2010) Immunity , vol.33 , pp. 955-966
    • Swiecki, M.1    Gilfillan, S.2    Vermi, W.3
  • 126
    • 84899518537 scopus 로고    scopus 로고
    • Cell depletion in mice that express diphtheria toxin receptor under the control of SiglecH encompasses more than plasmacytoid dendritic cells
    • COI: 1:CAS:528:DC%2BC2cXmsVGqsLw%3D, PID: 24683186
    • Swiecki M, Wang Y, Riboldi E et al (2014) Cell depletion in mice that express diphtheria toxin receptor under the control of SiglecH encompasses more than plasmacytoid dendritic cells. J Immunol 192:4409–4416. doi:10.4049/jimmunol.1303135
    • (2014) J Immunol , vol.192 , pp. 4409-4416
    • Swiecki, M.1    Wang, Y.2    Riboldi, E.3
  • 127
    • 0033177995 scopus 로고    scopus 로고
    • Conditional gene targeting in macrophages and granulocytes using LysMcre mice
    • COI: 1:CAS:528:DyaK1MXnsFSjtbw%3D, PID: 10621974
    • Clausen BE, Burkhardt C, Reith W et al (1999) Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res 8:265–277
    • (1999) Transgenic Res , vol.8 , pp. 265-277
    • Clausen, B.E.1    Burkhardt, C.2    Reith, W.3
  • 128
    • 84961726923 scopus 로고    scopus 로고
    • Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis
    • COI: 1:CAS:528:DC%2BC28XkvVCiu74%3D, PID: 27005831
    • Ohta T, Sugiyama M, Hemmi H et al (2016) Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis. Sci Rep 6:23505. doi:10.1038/srep23505
    • (2016) Sci Rep , vol.6 , pp. 23505
    • Ohta, T.1    Sugiyama, M.2    Hemmi, H.3
  • 129
    • 84934291436 scopus 로고    scopus 로고
    • Fate mapping of dendritic cells
    • Poltorak MP, Schraml BU (2015) Fate mapping of dendritic cells. Front Immun. doi:10.3389/fimmu.2015.00199
    • (2015) Front Immun
    • Poltorak, M.P.1    Schraml, B.U.2
  • 130
    • 84872434125 scopus 로고    scopus 로고
    • Advantages and limitations of mouse models to deplete dendritic cells
    • PID: 23322690
    • van Blijswijk J, Schraml BU, Reis E, Sousa C (2013) Advantages and limitations of mouse models to deplete dendritic cells. Eur J Immunol 43:22–26. doi:10.1002/eji.201243022
    • (2013) Eur J Immunol , vol.43 , pp. 22-26
    • van Blijswijk, J.1    Schraml, B.U.2    Reis, E.3    Sousa, C.4
  • 131
    • 33644836881 scopus 로고    scopus 로고
    • Fms-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain
    • COI: 1:CAS:528:DC%2BD28XitVSkurY%3D, PID: 16517725
    • Curtin JF, King GD, Barcia C et al (2006) Fms-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain. J Immunol 176:3566–3577
    • (2006) J Immunol , vol.176 , pp. 3566-3577
    • Curtin, J.F.1    King, G.D.2    Barcia, C.3
  • 132
    • 45549095991 scopus 로고    scopus 로고
    • Cutting edge: central nervous system plasmacytoid dendritic cells regulate the severity of relapsing experimental autoimmune encephalomyelitis
    • COI: 1:CAS:528:DC%2BD1cXltlCkt78%3D, PID: 18453561
    • Bailey-Bucktrout SL, Caulkins SC, Goings G et al (2008) Cutting edge: central nervous system plasmacytoid dendritic cells regulate the severity of relapsing experimental autoimmune encephalomyelitis. J Immunol 180:6457–6461
    • (2008) J Immunol , vol.180 , pp. 6457-6461
    • Bailey-Bucktrout, S.L.1    Caulkins, S.C.2    Goings, G.3
  • 133
    • 84866559134 scopus 로고    scopus 로고
    • A sphingosine-1-phosphate receptor 1-directed agonist reduces central nervous system inflammation in a plasmacytoid dendritic cell-dependent manner
    • COI: 1:CAS:528:DC%2BC38XhtlOmurjO, PID: 22933630
    • Galicia-Rosas G, Pikor N, Schwartz JA et al (2012) A sphingosine-1-phosphate receptor 1-directed agonist reduces central nervous system inflammation in a plasmacytoid dendritic cell-dependent manner. J Immunol 189:3700–3706. doi:10.4049/jimmunol.1102261
    • (2012) J Immunol , vol.189 , pp. 3700-3706
    • Galicia-Rosas, G.1    Pikor, N.2    Schwartz, J.A.3
  • 134
    • 84957436679 scopus 로고    scopus 로고
    • pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation
    • PID: 26341385
    • Duraes FV, Lippens C, Steinbach K et al (2015) pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation. J Autoimmun 67:8–18. doi:10.1016/j.jaut.2015.08.014
    • (2015) J Autoimmun , vol.67 , pp. 8-18
    • Duraes, F.V.1    Lippens, C.2    Steinbach, K.3
  • 135
    • 84943581188 scopus 로고    scopus 로고
    • DNGR-1(+) dendritic cells are located in meningeal membrane and choroid plexus of the noninjured brain
    • PID: 26184558
    • Quintana E, Fernández A, Velasco P et al (2015) DNGR-1(+) dendritic cells are located in meningeal membrane and choroid plexus of the noninjured brain. Glia 63:2231–2248. doi:10.1002/glia.22889
    • (2015) Glia , vol.63 , pp. 2231-2248
    • Quintana, E.1    Fernández, A.2    Velasco, P.3
  • 136
    • 84975299080 scopus 로고    scopus 로고
    • A case of mistaken identity: CD11c-eYFP(+) cells in the normal mouse brain parenchyma and neural retina display the phenotype of microglia, not dendritic cells
    • PID: 27189804
    • Dando SJ, Naranjo Golborne C, Chinnery HR et al (2016) A case of mistaken identity: CD11c-eYFP(+) cells in the normal mouse brain parenchyma and neural retina display the phenotype of microglia, not dendritic cells. Glia 64:1331–1349. doi:10.1002/glia.23005
    • (2016) Glia , vol.64 , pp. 1331-1349
    • Dando, S.J.1    Naranjo Golborne, C.2    Chinnery, H.R.3
  • 137
    • 84860004408 scopus 로고    scopus 로고
    • Viral-induced encephalitis initiates distinct and functional CD103+ CD11b+ brain dendritic cell populations within the olfactory bulb
    • PID: 22474352
    • D’Agostino PM, Kwak C, Vecchiarelli HA et al (2012) Viral-induced encephalitis initiates distinct and functional CD103+ CD11b+ brain dendritic cell populations within the olfactory bulb. Proc Natl Acad Sci U S A 109:6175–6180. doi:10.1073/pnas.1203941109
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 6175-6180
    • D’Agostino, P.M.1    Kwak, C.2    Vecchiarelli, H.A.3
  • 138
    • 84863632660 scopus 로고    scopus 로고
    • Follicular dendritic cells emerge from ubiquitous perivascular precursors
    • COI: 1:CAS:528:DC%2BC38XpvFGitr0%3D, PID: 22770220
    • Krautler NJ, Kana V, Kranich J et al (2012) Follicular dendritic cells emerge from ubiquitous perivascular precursors. Cell 150:194–206. doi:10.1016/j.cell.2012.05.032
    • (2012) Cell , vol.150 , pp. 194-206
    • Krautler, N.J.1    Kana, V.2    Kranich, J.3
  • 139
    • 34249700046 scopus 로고    scopus 로고
    • Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology
    • PID: 17438020
    • Magliozzi R, Howell O, Vora A et al (2007) Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain 130:1089–1104. doi:10.1093/brain/awm038
    • (2007) Brain , vol.130 , pp. 1089-1104
    • Magliozzi, R.1    Howell, O.2    Vora, A.3
  • 140
    • 84963613008 scopus 로고    scopus 로고
    • Integration of Th17- and Lymphotoxin-derived signals initiates meningeal-resident stromal cell remodeling to propagate neuroinflammation
    • COI: 1:CAS:528:DC%2BC2MXitVajtLbF, PID: 26682987
    • Pikor NB, Astarita JL, Summers-Deluca L et al (2015) Integration of Th17- and Lymphotoxin-derived signals initiates meningeal-resident stromal cell remodeling to propagate neuroinflammation. Immunity 43:1160–1173. doi:10.1016/j.immuni.2015.11.010
    • (2015) Immunity , vol.43 , pp. 1160-1173
    • Pikor, N.B.1    Astarita, J.L.2    Summers-Deluca, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.