메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR; GAMMA CHEMOKINE; XC CHEMOKINE RECEPTOR 1, MOUSE; XCL1 PROTEIN, MOUSE;

EID: 84961726923     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep23505     Document Type: Article
Times cited : (97)

References (53)
  • 1
    • 84921786777 scopus 로고    scopus 로고
    • Regional specialization within the intestinal immune system
    • Mowat, A. M. & Agace, W. W. Regional specialization within the intestinal immune system. Nat. Rev. Immunol. 14, 667-685 (2014).
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 667-685
    • Mowat, A.M.1    Agace, W.W.2
  • 3
    • 84897053496 scopus 로고    scopus 로고
    • Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis
    • Mortha, A. et al. Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis. Science 343, 1249-1288 (2014).
    • (2014) Science , vol.343 , pp. 1249-1288
    • Mortha, A.1
  • 4
    • 77349124883 scopus 로고    scopus 로고
    • Origin and development of dendritic cells
    • Liu, K. & Nussenzweig, M. C. Origin and development of dendritic cells. Immunol. Rev. 234, 45-54 (2010).
    • (2010) Immunol. Rev. , vol.234 , pp. 45-54
    • Liu, K.1    Nussenzweig, M.C.2
  • 5
    • 84875528275 scopus 로고    scopus 로고
    • The dendritic cell lineage: Ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting
    • Merad, M., Sathe, P., Helft, J., Miller, J. & Mortha, A. The dendritic cell lineage: Ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. Annu. Rev. Immunol. 31, 563-604 (2013).
    • (2013) Annu. Rev. Immunol. , vol.31 , pp. 563-604
    • Merad, M.1    Sathe, P.2    Helft, J.3    Miller, J.4    Mortha, A.5
  • 6
    • 34547757390 scopus 로고    scopus 로고
    • Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
    • Sun, C. M. et al. Small intestine lamina propria dendritic cells promote De novo generation of Foxp3 T reg cells via retinoic acid. J. Exp. Med. 204, 1775-1785 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 1775-1785
    • Sun, C.M.1
  • 7
    • 34547788180 scopus 로고    scopus 로고
    • A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGFbeta and retinoic acid-dependent mechanism
    • Coombes, J. L. et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGFbeta and retinoic acid-dependent mechanism. J. Exp. Med. 204, 1757-1764 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 1757-1764
    • Coombes, J.L.1
  • 8
    • 84878167904 scopus 로고    scopus 로고
    • IRF4 transcription-factor-dependent CD103(+ )CD11b(+ ) dendritic cells drive mucosal T helper 17 cell differentiation
    • Persson, E. K. et al. IRF4 transcription-factor-dependent CD103(+ )CD11b(+ ) dendritic cells drive mucosal T helper 17 cell differentiation. Immunity 38, 958-969 (2013).
    • (2013) Immunity , vol.38 , pp. 958-969
    • Persson, E.K.1
  • 9
    • 84878191150 scopus 로고    scopus 로고
    • IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses
    • Schlitzer, A. et al. IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses. Immunity 38, 970-983 (2013).
    • (2013) Immunity , vol.38 , pp. 970-983
    • Schlitzer, A.1
  • 10
    • 84885447087 scopus 로고    scopus 로고
    • Intestinal lamina propria dendritic cells maintain T cell homeostasis but do not affect commensalism
    • Welty, N. E. et al. Intestinal lamina propria dendritic cells maintain T cell homeostasis but do not affect commensalism. J. Exp. Med. 210, 2011-2024 (2013).
    • (2013) J. Exp. Med. , vol.210 , pp. 2011-2024
    • Welty, N.E.1
  • 11
    • 79960513242 scopus 로고    scopus 로고
    • Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization
    • Denning, T. L. et al. Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization. J. Immunol. 187, 733-747 (2011).
    • (2011) J. Immunol. , vol.187 , pp. 733-747
    • Denning, T.L.1
  • 12
    • 84859452120 scopus 로고    scopus 로고
    • Intestinal CX3C chemokine receptor 1(high) (CX3CR1(high)) myeloid cells prevent T-cell-dependent colitis
    • Kayama, H. et al. Intestinal CX3C chemokine receptor 1(high) (CX3CR1(high)) myeloid cells prevent T-cell-dependent colitis. Proc. Natl. Acad. Sci. USA 109, 5010-5015 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 5010-5015
    • Kayama, H.1
  • 13
    • 84874207519 scopus 로고    scopus 로고
    • Expression of xcr1 characterizes the batf3-dependent lineage of dendritic cells capable of antigen cross-presentation
    • Bachem, A. et al. Expression of XCR1 Characterizes the Batf3-Dependent Lineage of Dendritic Cells Capable of Antigen Cross-Presentation. Front. Immunol. 3, 214 (2012).
    • (2012) Front. Immunol. , vol.3 , pp. 214
    • Bachem, A.1
  • 14
    • 84905651006 scopus 로고    scopus 로고
    • Ontogenic, phenotypic, and functional characterization of xcr1(+ ) dendritic cells leads to a consistent classification of intestinal dendritic cells based on the expression of xcr1 and sirpalpha
    • Becker, M. et al. Ontogenic, Phenotypic, and Functional Characterization of XCR1(+ ) Dendritic Cells Leads to a Consistent Classification of Intestinal Dendritic Cells Based on the Expression of XCR1 and SIRPalpha. Front. Immunol. 5, 326 (2014).
    • (2014) Front. Immunol. , vol.5 , pp. 326
    • Becker, M.1
  • 15
    • 70449518424 scopus 로고    scopus 로고
    • Selective expression of the chemokine receptor XCR1 on cross-presenting dendritic cells determines cooperation with CD8+ T cells
    • Dorner, B. G. et al. Selective expression of the chemokine receptor XCR1 on cross-presenting dendritic cells determines cooperation with CD8+ T cells. Immunity 31, 823-833 (2009).
    • (2009) Immunity , vol.31 , pp. 823-833
    • Dorner, B.G.1
  • 16
    • 84879109606 scopus 로고    scopus 로고
    • Critical roles of a dendritic cell subset expressing a chemokine receptor XCR1
    • Yamazaki, C. et al. Critical roles of a dendritic cell subset expressing a chemokine receptor, XCR1. J. Immunol. 190, 6071-6082 (2013).
    • (2013) J. Immunol. , vol.190 , pp. 6071-6082
    • Yamazaki, C.1
  • 17
    • 77349100571 scopus 로고    scopus 로고
    • The CD8+ dendritic cell subset
    • Shortman, K. & Heath, W. R. The CD8+ dendritic cell subset. Immunol. Rev. 234, 18-31 (2010).
    • (2010) Immunol. Rev. , vol.234 , pp. 18-31
    • Shortman, K.1    Heath, W.R.2
  • 18
    • 84879689439 scopus 로고    scopus 로고
    • Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks
    • Murphy, T. L., Tussiwand, R. & Murphy, K. M. Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks. Nat. Rev. Immunol. 13, 499-509 (2013).
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 499-509
    • Murphy, T.L.1    Tussiwand, R.2    Murphy, K.M.3
  • 19
    • 41349119601 scopus 로고    scopus 로고
    • The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse
    • Tailor, P., Tamura, T., Morse, H. C. 3rd & Ozato, K. The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse. Blood 111, 1942-1945 (2008).
    • (2008) Blood , vol.111 , pp. 1942-1945
    • Tailor, P.1    Tamura, T.2    Morse, H.C.3    Ozato, K.4
  • 20
    • 56449097442 scopus 로고    scopus 로고
    • Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity
    • Hildner, K. et al. Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity. Science 322, 1097-1100 (2008).
    • (2008) Science , vol.322 , pp. 1097-1100
    • Hildner, K.1
  • 21
    • 84901415239 scopus 로고    scopus 로고
    • Complementary diversification of dendritic cells and innate lymphoid cells
    • Briseno, C. G., Murphy, T. L. & Murphy, K. M. Complementary diversification of dendritic cells and innate lymphoid cells. Curr. Opin. Immunol. 29, 69-78 (2014).
    • (2014) Curr. Opin. Immunol. , vol.29 , pp. 69-78
    • Briseno, C.G.1    Murphy, T.L.2    Murphy, K.M.3
  • 22
    • 77953522371 scopus 로고    scopus 로고
    • Superior antigen cross-presentation and XCR1 expression define human CD11c+ CD141+ cells as homologues of mouse CD8+ dendritic cells
    • Bachem, A. et al. Superior antigen cross-presentation and XCR1 expression define human CD11c+ CD141+ cells as homologues of mouse CD8+ dendritic cells. J. Exp. Med. 207, 1273-1281 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 1273-1281
    • Bachem, A.1
  • 23
    • 77953506509 scopus 로고    scopus 로고
    • The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cells
    • Crozat, K. et al. The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cells. J. Exp. Med. 207, 1283-1292 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 1283-1292
    • Crozat, K.1
  • 24
    • 84864293006 scopus 로고    scopus 로고
    • Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells
    • Haniffa, M. et al. Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells. Immunity 37, 60-73 (2012).
    • (2012) Immunity , vol.37 , pp. 60-73
    • Haniffa, M.1
  • 25
    • 0034144269 scopus 로고    scopus 로고
    • Chemokines: A new classification system and their role in immunity
    • Zlotnik, A. & Yoshie, O. Chemokines: A new classification system and their role in immunity. Immunity 12, 121-127 (2000).
    • (2000) Immunity , vol.12 , pp. 121-127
    • Zlotnik, A.1    Yoshie, O.2
  • 26
    • 79951715831 scopus 로고    scopus 로고
    • Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development
    • Lei, Y. et al. Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development. J. Exp. Med. 208, 383-394 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 383-394
    • Lei, Y.1
  • 27
    • 79959664629 scopus 로고    scopus 로고
    • The light and dark sides of intestinal intraepithelial lymphocytes
    • Cheroutre, H., Lambolez, F. & Mucida, D. The light and dark sides of intestinal intraepithelial lymphocytes. Nat. Rev. Immunol. 11, 445-456 (2011).
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 445-456
    • Cheroutre, H.1    Lambolez, F.2    Mucida, D.3
  • 28
    • 53849098346 scopus 로고    scopus 로고
    • T-cell recruitment to the intestinal mucosa
    • Agace, W. W. T-cell recruitment to the intestinal mucosa. Trends Immunol. 29, 514-522 (2008).
    • (2008) Trends Immunol. , vol.29 , pp. 514-522
    • Agace, W.W.1
  • 29
    • 0035525789 scopus 로고    scopus 로고
    • Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T-and B-cell development and a reduction in T-cell receptor gammadelta(+ ) gut intraepithelial lymphocytes
    • Wurbel, M. A. et al. Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T-and B-cell development and a reduction in T-cell receptor gammadelta(+ ) gut intraepithelial lymphocytes. Blood 98, 2626-2632 (2001).
    • (2001) Blood , vol.98 , pp. 2626-2632
    • Wurbel, M.A.1
  • 30
    • 85027952412 scopus 로고    scopus 로고
    • Transcriptional reprogramming of mature CD4(+ ) helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes
    • Mucida, D. et al. Transcriptional reprogramming of mature CD4(+ ) helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes. Nat. Immunol. 14, 281-289 (2013).
    • (2013) Nat. Immunol. , vol.14 , pp. 281-289
    • Mucida, D.1
  • 31
    • 85027933013 scopus 로고    scopus 로고
    • Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4(+ ) T cell immunity
    • Reis, B. S., Rogoz, A., Costa-Pinto, F. A., Taniuchi, I. & Mucida, D. Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4(+ ) T cell immunity. Nat. Immunol. 14, 271-280 (2013).
    • (2013) Nat. Immunol. , vol.14 , pp. 271-280
    • Reis, B.S.1    Rogoz, A.2    Costa-Pinto, F.A.3    Taniuchi, I.4    Mucida, D.5
  • 32
    • 84867899425 scopus 로고    scopus 로고
    • Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells
    • 1721
    • Weiss, J. M. et al. Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells. J. Exp. Med. 209, 1723-1742, S1721 (2012).
    • (2012) J. Exp. Med. , vol.209 , pp. 1723-1742
    • Weiss, J.M.1
  • 33
    • 77349093593 scopus 로고    scopus 로고
    • Defining dendritic cells by conditional and constitutive cell ablation
    • Bar-On, L. & Jung, S. Defining dendritic cells by conditional and constitutive cell ablation. Immunol. Rev. 234, 76-89 (2010).
    • (2010) Immunol. Rev. , vol.234 , pp. 76-89
    • Bar-On, L.1    Jung, S.2
  • 34
    • 77349083495 scopus 로고    scopus 로고
    • Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells
    • Edelson, B. T. et al. Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells. J. Exp. Med. 207, 823-836 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 823-836
    • Edelson, B.T.1
  • 35
    • 84961687508 scopus 로고    scopus 로고
    • Intestinal CD103+ CD11b- dendritic cells restrain colitis via IFN-?-induced anti-inflammatory response in epithelial cells
    • [Epub ahead of print]
    • Muzaki A. R. et al. Intestinal CD103+ CD11b- dendritic cells restrain colitis via IFN-?-induced anti-inflammatory response in epithelial cells. Mucosal Immunol. [Epub ahead of print]
    • Mucosal Immunol.
    • Muzaki, A.R.1
  • 36
    • 0033214348 scopus 로고    scopus 로고
    • CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
    • Forster, R. et al. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99, 23-33 (1999).
    • (1999) Cell , vol.99 , pp. 23-33
    • Forster, R.1
  • 37
    • 0028006855 scopus 로고
    • Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice
    • Dieleman, L. A. et al. Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice. Gastroenterology 107, 1643-1652 (1994).
    • (1994) Gastroenterology , vol.107 , pp. 1643-1652
    • Dieleman, L.A.1
  • 38
    • 0037195101 scopus 로고    scopus 로고
    • Protection of the intestinal mucosa by intraepithelial gamma delta T cells
    • Chen, Y., Chou, K., Fuchs, E., Havran, W. L. & Boismenu, R. Protection of the intestinal mucosa by intraepithelial gamma delta T cells. Proc. Natl. Acad. Sci. USA 99, 14338-14343 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 14338-14343
    • Chen, Y.1    Chou, K.2    Fuchs, E.3    Havran, W.L.4    Boismenu, R.5
  • 39
    • 0037965755 scopus 로고    scopus 로고
    • An important regulatory role for CD4+ CD8 alpha alpha T cells in the intestinal epithelial layer in the prevention of inflammatory bowel disease
    • Das, G. et al. An important regulatory role for CD4+ CD8 alpha alpha T cells in the intestinal epithelial layer in the prevention of inflammatory bowel disease. Proc. Natl. Acad. Sci. USA 100, 5324-5329 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 5324-5329
    • Das, G.1
  • 40
    • 33845903050 scopus 로고    scopus 로고
    • Aggravation of intestinal inflammation by depletion/deficiency of gammadelta T cells in different types of IBD animal models
    • Kuhl, A. A. et al. Aggravation of intestinal inflammation by depletion/deficiency of gammadelta T cells in different types of IBD animal models. J. Leukoc. Biol. 81, 168-175 (2007).
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 168-175
    • Kuhl, A.A.1
  • 41
    • 80155164160 scopus 로고    scopus 로고
    • Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation
    • Li, Y. et al. Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation. Cell 147, 629-640 (2011).
    • (2011) Cell , vol.147 , pp. 629-640
    • Li, Y.1
  • 42
    • 0242494273 scopus 로고    scopus 로고
    • Role of gamma delta T cells in the inflammatory response of experimental colitis mice
    • Tsuchiya, T. et al. Role of gamma delta T cells in the inflammatory response of experimental colitis mice. J. Immunol. 171, 5507-5513 (2003).
    • (2003) J. Immunol. , vol.171 , pp. 5507-5513
    • Tsuchiya, T.1
  • 43
    • 84867884822 scopus 로고    scopus 로고
    • Compensatory dendritic cell development mediated by BATF-IRF interactions
    • Tussiwand, R. et al. Compensatory dendritic cell development mediated by BATF-IRF interactions. Nature 490, 502-507 (2012).
    • (2012) Nature , vol.490 , pp. 502-507
    • Tussiwand, R.1
  • 44
    • 33846798312 scopus 로고    scopus 로고
    • Intraepithelial lymphocytes: Their shared and divergent immunological behaviors in the small and large intestine
    • Kunisawa, J., Takahashi, I. & Kiyono, H. Intraepithelial lymphocytes: Their shared and divergent immunological behaviors in the small and large intestine. Immunol. Rev. 215, 136-153 (2007).
    • (2007) Immunol. Rev. , vol.215 , pp. 136-153
    • Kunisawa, J.1    Takahashi, I.2    Kiyono, H.3
  • 45
    • 84886832604 scopus 로고    scopus 로고
    • Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes
    • Jiang, W. et al. Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes. J. Exp. Med. 210, 2465-2476 (2013).
    • (2013) J. Exp. Med. , vol.210 , pp. 2465-2476
    • Jiang, W.1
  • 46
    • 84894107663 scopus 로고    scopus 로고
    • Oral tolerance can be established via gap junction transfer of fed antigens from CX3CR1(+ ) macrophages to CD103(+ ) dendritic cells
    • Mazzini, E., Massimiliano, L., Penna, G. & Rescigno, M. Oral tolerance can be established via gap junction transfer of fed antigens from CX3CR1(+ ) macrophages to CD103(+ ) dendritic cells. Immunity 40, 248-261 (2014).
    • (2014) Immunity , vol.40 , pp. 248-261
    • Mazzini, E.1    Massimiliano, L.2    Penna, G.3    Rescigno, M.4
  • 47
    • 19344361971 scopus 로고    scopus 로고
    • TGF-{beta}-dependent CD103 expression by CD8(+ ) T cells promotes selective destruction of the host intestinal epithelium during graft-versus-host disease
    • El-Asady, R. et al. TGF-{beta}-dependent CD103 expression by CD8(+ ) T cells promotes selective destruction of the host intestinal epithelium during graft-versus-host disease. J. Exp. Med. 201, 1647-1657 (2005).
    • (2005) J. Exp. Med. , vol.201 , pp. 1647-1657
    • El-Asady, R.1
  • 48
    • 0033151953 scopus 로고    scopus 로고
    • Mucosal T lymphocyte numbers are selectively reduced in integrin alpha e (CD103)-deficient mice
    • Schon, M. P. et al. Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice. J. Immunol. 162, 6641-6649 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 6641-6649
    • Schon, M.P.1
  • 49
    • 79952921526 scopus 로고    scopus 로고
    • Control of the development of CD8alphaalpha+ intestinal intraepithelial lymphocytes by TGF-beta
    • Konkel, J. E. et al. Control of the development of CD8alphaalpha+ intestinal intraepithelial lymphocytes by TGF-beta. Nat. Immunol. 12, 312-319 (2011).
    • (2011) Nat. Immunol. , vol.12 , pp. 312-319
    • Konkel, J.E.1
  • 50
    • 70049098070 scopus 로고    scopus 로고
    • Origin of the lamina propria dendritic cell network
    • Bogunovic, M. et al. Origin of the lamina propria dendritic cell network. Immunity 31, 513-525 (2009).
    • (2009) Immunity , vol.31 , pp. 513-525
    • Bogunovic, M.1
  • 51
    • 33746860835 scopus 로고    scopus 로고
    • An improved mouse line for Cre-induced cell ablation due to diphtheria toxin A, expressed from the Rosa26 locus
    • Brockschnieder, D., Pechmann, Y., Sonnenberg-Riethmacher, E. & Riethmacher, D. An improved mouse line for Cre-induced cell ablation due to diphtheria toxin A, expressed from the Rosa26 locus. Genesis 44, 322-327 (2006).
    • (2006) Genesis , vol.44 , pp. 322-327
    • Brockschnieder, D.1    Pechmann, Y.2    Sonnenberg-Riethmacher, E.3    Riethmacher, D.4
  • 52
    • 0031577470 scopus 로고    scopus 로고
    • A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission
    • Sakai, K. & Miyazaki, J. A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission. Biochem. Biophys. Res. Commun. 237, 318-324 (1997).
    • (1997) Biochem. Biophys. Res. Commun. , vol.237 , pp. 318-324
    • Sakai, K.1    Miyazaki, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.