Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells

Developmental Cell

Volumn 39, Issue 4, 2016, Pages 491-507

  Li, Guang ^a   Xu, Adele ^a   Sim, Sopheak ^a   Priest, James R ^a   Tian, Xueying ^b   Khan, Tooba ^c   Quertermous, Thomas ^a   Zhou, Bin ^b   Tsao, Philip S ^a,c   Quake, Stephen R ^a,d   Wu, Sean M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d Stanford University   (United States)

Author keywords

cardiac development; cardiomyocyte; congenital heart disease; Nkx2 5; single cell RNA sequencing

Indexed keywords

SMALL CYTOPLASMIC RNA; TRANSCRIPTION FACTOR NKX2.5; BIOLOGICAL MARKER; CRE RECOMBINASE; INTEGRASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; CELL LINEAGE; CELL SUBPOPULATION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EMBRYO; EMBRYO CELL; EMBRYO PATTERN FORMATION; EMBRYONIC CARDIAC CELL; GENE EXPRESSION PROFILING; GENE MAPPING; HEART DEVELOPMENT; HEART VENTRICLE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RNA SEQUENCE; TRANSCRIPTOMICS; ALGORITHM; ANIMAL; BIOLOGICAL MODEL; CARDIAC MUSCLE; CELL SEPARATION; CYTOLOGY; EMBRYOID BODY; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENETICS; HEART; MAMMALIAN EMBRYO; METABOLISM; POLYMERASE CHAIN REACTION; REPRODUCIBILITY; SEQUENCE ANALYSIS; SINGLE CELL ANALYSIS;

ALGORITHMS; ANIMALS; BIOMARKERS; CELL LINEAGE; CELL SEPARATION; EMBRYO, MAMMALIAN; EMBRYOID BODIES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; INTEGRASES; MICE; MODELS, BIOLOGICAL; MYOCARDIUM; MYOCYTES, CARDIAC; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; SEQUENCE ANALYSIS, RNA; SINGLE-CELL ANALYSIS;

EID: 84997080388     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2016.10.014     Document Type: Article

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