메뉴 건너뛰기




Volumn 7, Issue 45, 2016, Pages 74380-74392

Erratum: Discovery and clinical introduction of first-in-class imipridone onc201 (Oncotarget. (2016) 7 (74380-74392) DOI: 10.18632/oncotarget.11814);Discovery and clinical introduction of first-in-class imipridone ONC201

(32)  Allen, Joshua E a   Kline, C Leah B b   Prabhu, Varun V a   Wagner, Jessica b   Ishizawa, Jo c   Madhukar, Neel d   Lev, Avital b   Baumeister, Marie b   Zhou, Lanlan b   Lulla, Amriti b   Stogniew, Martin a   Schalop, Lee a   Benes, Cyril e,f   Kaufman, Howard L g   Pottorf, Richard S h   Rao Nallaganchu, B h   Olson, Gary L h   Al Mulla, Fahd i   Duvic, Madeleine c   Wu, Gen Sheng j   more..


Author keywords

ATF4; DRD2; Integrated stress response; ONC201; TIC10

Indexed keywords

7 BENZYL 4 (2 METHYLBENZYL) 1,2,6,7,8,9 HEXAHYDROIMIDAZO[1,2 A]PYRIDO[3,4 E]PYRIMIDIN 5(AH)ONE; ANTINEOPLASTIC AGENT; AZACITIDINE; BEVACIZUMAB; BORTEZOMIB; CYTARABINE; DACARBAZINE; DEATH RECEPTOR 5; DOCETAXEL; FLUOROURACIL; GEMCITABINE; HYDROXYUREA; IBRUTINIB; MITOGEN ACTIVATED PROTEIN KINASE; NAVITOCLAX; PACLITAXEL; PROTEIN KINASE B; PYRIMIDINE DERIVATIVE; SORAFENIB; TEMOZOLOMIDE; TRANSCRIPTION FACTOR FKHRL1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; VENETOCLAX; FUSED HETEROCYCLIC RINGS; TIC10 COMPOUND;

EID: 84995802992     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/ONCOTARGET.28012     Document Type: Erratum
Times cited : (111)

References (47)
  • 2
    • 84929149021 scopus 로고    scopus 로고
    • Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway
    • Allen JE, Krigsfeld G, Patel L, Mayes PA, Dicker DT, Wu GS, El-Deiry WS. Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway. Mol Cancer. 2015; 14: 99. doi: 10.1186/s12943-015-0346-9.
    • (2015) Mol Cancer , vol.14 , pp. 99
    • Allen, J.E.1    Krigsfeld, G.2    Patel, L.3    Mayes, P.A.4    Dicker, D.T.5    Wu, G.S.6    El-Deiry, W.S.7
  • 3
    • 65449152836 scopus 로고    scopus 로고
    • Following TRAIL's path in the immune system
    • Falschlehner C, Schaefer U, Walczak H. Following TRAIL's path in the immune system. Immunology. 2009; 127: 145-54. doi: 10.1111/j.1365-2567.2009.03058.x.
    • (2009) Immunology , vol.127 , pp. 145-154
    • Falschlehner, C.1    Schaefer, U.2    Walczak, H.3
  • 4
    • 0037033005 scopus 로고    scopus 로고
    • FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer
    • Modur V, Nagarajan R, Evers BM, Milbrandt J. FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer. J Biol Chem. 2002; 277: 47928-37. doi: 10.1074/jbc.M207509200.
    • (2002) J Biol Chem , vol.277 , pp. 47928-47937
    • Modur, V.1    Nagarajan, R.2    Evers, B.M.3    Milbrandt, J.4
  • 5
    • 11144294668 scopus 로고    scopus 로고
    • From worm to human: bioinformatics approaches to identify FOXO target genes
    • Xuan Z, Zhang MQ. From worm to human: bioinformatics approaches to identify FOXO target genes. Mech Ageing Dev. 2005; 126: 209-15. doi: 10.1016/j.mad.2004.09.021.
    • (2005) Mech Ageing Dev , vol.126 , pp. 209-215
    • Xuan, Z.1    Zhang, M.Q.2
  • 8
    • 84959077995 scopus 로고    scopus 로고
    • ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2alpha kinases
    • Kline CL, Van den Heuvel AP, Allen JE, Prabhu VV, Dicker DT, El-Deiry WS. ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2alpha kinases. Sci Signal. 2016; 9: ra18. doi: 10.1126/scisignal.aac4374.
    • (2016) Sci Signal , vol.9
    • Kline, C.L.1    Van den Heuvel, A.P.2    Allen, J.E.3    Prabhu, V.V.4    Dicker, D.T.5    El-Deiry, W.S.6
  • 11
    • 21344453520 scopus 로고    scopus 로고
    • Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein
    • Yoshida T, Shiraishi T, Nakata S, Horinaka M, Wakada M, Mizutani Y, Miki T, Sakai T. Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein. Cancer Res. 2005; 65: 5662-7. doi: 10.1158/0008-5472.CAN-05-0693.
    • (2005) Cancer Res , vol.65 , pp. 5662-5667
    • Yoshida, T.1    Shiraishi, T.2    Nakata, S.3    Horinaka, M.4    Wakada, M.5    Mizutani, Y.6    Miki, T.7    Sakai, T.8
  • 12
    • 54749084254 scopus 로고    scopus 로고
    • Coupling of endoplasmic reticulum stress to CDDO-Me-induced up-regulation of death receptor 5 via a CHOP-dependent mechanism involving JNK activation
    • Zou W, Yue P, Khuri FR, Sun SY. Coupling of endoplasmic reticulum stress to CDDO-Me-induced up-regulation of death receptor 5 via a CHOP-dependent mechanism involving JNK activation. Cancer Res. 2008; 68: 7484-92. doi: 10.1158/0008-5472.CAN-08-1318.
    • (2008) Cancer Res , vol.68 , pp. 7484-7492
    • Zou, W.1    Yue, P.2    Khuri, F.R.3    Sun, S.Y.4
  • 14
    • 84959104620 scopus 로고    scopus 로고
    • ONC201: Stressing tumors to death
    • Endo Greer Y, Lipkowitz S. ONC201: Stressing tumors to death. Sci Signal. 2016; 9: fs1. doi: 10.1126/scisignal. aad7955.
    • (2016) Sci Signal , vol.9
    • Endo Greer, Y.1    Lipkowitz, S.2
  • 15
    • 17144417669 scopus 로고    scopus 로고
    • TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
    • Ohoka N, Yoshii S, Hattori T, Onozaki K, Hayashi H. TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death. EMBO J. 2005; 24: 1243-55. doi: 10.1038/sj.emboj.7600596.
    • (2005) EMBO J , vol.24 , pp. 1243-1255
    • Ohoka, N.1    Yoshii, S.2    Hattori, T.3    Onozaki, K.4    Hayashi, H.5
  • 16
    • 0038242819 scopus 로고    scopus 로고
    • TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver
    • Du K, Herzig S, Kulkarni RN, Montminy M. TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science. 2003; 300: 1574-7. doi: 10.1126/science.1079817.
    • (2003) Science , vol.300 , pp. 1574-1577
    • Du, K.1    Herzig, S.2    Kulkarni, R.N.3    Montminy, M.4
  • 19
    • 84897419234 scopus 로고    scopus 로고
    • Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma
    • Li J, Zhu S, Kozono D, Ng K, Futalan D, Shen Y, Akers JC, Steed T, Kushwaha D, Schlabach M, Carter BS, Kwon CH, Furnari F, et al. Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma. Oncotarget. 2014; 5: 882-93. doi: 10.18632/oncotarget.1801.
    • (2014) Oncotarget , vol.5 , pp. 882-893
    • Li, J.1    Zhu, S.2    Kozono, D.3    Ng, K.4    Futalan, D.5    Shen, Y.6    Akers, J.C.7    Steed, T.8    Kushwaha, D.9    Schlabach, M.10    Carter, B.S.11    Kwon, C.H.12    Furnari, F.13
  • 20
    • 33748622833 scopus 로고    scopus 로고
    • Dopamine targets cycling B cells independent of receptors/transporter for oxidative attack: Implications for non-Hodgkin's lymphoma
    • Meredith EJ, Holder MJ, Rosen A, Lee AD, Dyer MJ, Barnes NM, Gordon J. Dopamine targets cycling B cells independent of receptors/transporter for oxidative attack: Implications for non-Hodgkin's lymphoma. Proc Natl Acad Sci U S A. 2006; 103: 13485-90. doi: 10.1073/pnas.0605993103.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 13485-13490
    • Meredith, E.J.1    Holder, M.J.2    Rosen, A.3    Lee, A.D.4    Dyer, M.J.5    Barnes, N.M.6    Gordon, J.7
  • 21
    • 78650845707 scopus 로고    scopus 로고
    • G protein-coupled receptors: novel targets for drug discovery in cancer
    • Lappano R, Maggiolini M. G protein-coupled receptors: novel targets for drug discovery in cancer. Nat Rev Drug Discov. 2011; 10: 47-60. doi: 10.1038/nrd3320.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 47-60
    • Lappano, R.1    Maggiolini, M.2
  • 22
    • 77955643939 scopus 로고    scopus 로고
    • Role of endoplasmic reticulum stress in alpha-TEA mediated TRAIL/DR5 death receptor dependent apoptosis
    • Tiwary R, Yu W, Li J, Park SK, Sanders BG, Kline K. Role of endoplasmic reticulum stress in alpha-TEA mediated TRAIL/DR5 death receptor dependent apoptosis. PLoS One. 2010; 5: e11865. doi: 10.1371/journal.pone.0011865.
    • (2010) PLoS One , vol.5
    • Tiwary, R.1    Yu, W.2    Li, J.3    Park, S.K.4    Sanders, B.G.5    Kline, K.6
  • 23
    • 84995798408 scopus 로고    scopus 로고
    • TRAIL pathway inducer ONC201/TIC10 primes multiple myeloma cells (MM) for apoptosis by downregulating X-linked inhibitor of apoptosis
    • Kline CL, Lulla AR, Dicker DT, Allen JE, El-Deiry WS. TRAIL pathway inducer ONC201/TIC10 primes multiple myeloma cells (MM) for apoptosis by downregulating X-linked inhibitor of apoptosis. Cancer Res. 2015; 75: 2942. doi: doi: 10.1158/1538-7445.AM2015-2942.
    • (2015) Cancer Res , vol.75 , pp. 2942
    • Kline, C.L.1    Lulla, A.R.2    Dicker, D.T.3    Allen, J.E.4    El-Deiry, W.S.5
  • 24
    • 84943811613 scopus 로고    scopus 로고
    • ONC201 induces cell death in pediatric non-Hodgkin's lymphoma cells
    • Talekar MK, Allen JE, Dicker DT, El-Deiry WS. ONC201 induces cell death in pediatric non-Hodgkin's lymphoma cells. Cell Cycle. 2015; 14: 2422-8. doi: 10.1080/15384101.2015.1054086.
    • (2015) Cell Cycle , vol.14 , pp. 2422-2428
    • Talekar, M.K.1    Allen, J.E.2    Dicker, D.T.3    El-Deiry, W.S.4
  • 26
    • 84995762609 scopus 로고    scopus 로고
    • ONC201 Induces Apoptosis in Cutaneous T-Cell Lymphoma Cells through a Mechanism That Involves the Integrated Stress Response and Inactivation of Jak/Stat Signaling
    • Duvic M, Zhang X, Ni X, Langridge T, Tarapore R, Allen JE. ONC201 Induces Apoptosis in Cutaneous T-Cell Lymphoma Cells through a Mechanism That Involves the Integrated Stress Response and Inactivation of Jak/Stat Signaling. Blood. 2015; 126: 4011.
    • (2015) Blood , vol.126 , pp. 4011
    • Duvic, M.1    Zhang, X.2    Ni, X.3    Langridge, T.4    Tarapore, R.5    Allen, J.E.6
  • 27
    • 84915818510 scopus 로고    scopus 로고
    • Deregulation in STAT signaling is important for cutaneous T-cell lymphoma (CTCL) pathogenesis and cancer progression
    • Netchiporouk E, Litvinov IV, Moreau L, Gilbert M, Sasseville D, Duvic M. Deregulation in STAT signaling is important for cutaneous T-cell lymphoma (CTCL) pathogenesis and cancer progression. Cell Cycle. 2014; 13: 3331-5. doi: 10.4161/15384101.2014.965061.
    • (2014) Cell Cycle , vol.13 , pp. 3331-3335
    • Netchiporouk, E.1    Litvinov, I.V.2    Moreau, L.3    Gilbert, M.4    Sasseville, D.5    Duvic, M.6
  • 31
    • 84929220565 scopus 로고    scopus 로고
    • Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem-like Cells in an Akt/Foxo3a/TRAIL-Dependent Manner
    • Prabhu VV, Allen JE, Dicker DT, El-Deiry WS. Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem-like Cells in an Akt/Foxo3a/TRAIL-Dependent Manner. Cancer Res. 2015; 75: 1423-32. doi: 10.1158/0008-5472.CAN-13-3451.
    • (2015) Cancer Res , vol.75 , pp. 1423-1432
    • Prabhu, V.V.1    Allen, J.E.2    Dicker, D.T.3    El-Deiry, W.S.4
  • 32
    • 84940467163 scopus 로고    scopus 로고
    • Cancer stem cells: a potential target for cancer therapy
    • Qiu H, Fang X, Luo Q, Ouyang G. Cancer stem cells: a potential target for cancer therapy. Cell Mol Life Sci. 2015; 72: 3411-24. doi: 10.1007/s00018-015-1920-4.
    • (2015) Cell Mol Life Sci , vol.72 , pp. 3411-3424
    • Qiu, H.1    Fang, X.2    Luo, Q.3    Ouyang, G.4
  • 33
    • 79952370202 scopus 로고    scopus 로고
    • The cancer stem cell: premises, promises and challenges
    • Clevers H. The cancer stem cell: premises, promises and challenges. Nat Med. 2011; 17: 313-9. doi: 10.1038/nm.2304.
    • (2011) Nat Med , vol.17 , pp. 313-319
    • Clevers, H.1
  • 35
    • 84946866494 scopus 로고    scopus 로고
    • TIC10/ONC201 synergizes with Bcl-2/Bcl-xL inhibition in glioblastoma by suppression of Mcl-1 and its binding partners in vitro and in vivo
    • Karpel-Massler G, Ba M, Shu C, Halatsch ME, Westhoff MA, Bruce JN, Canoll P, Siegelin MD. TIC10/ONC201 synergizes with Bcl-2/Bcl-xL inhibition in glioblastoma by suppression of Mcl-1 and its binding partners in vitro and in vivo. Oncotarget. 2015; 6: 36456-71. doi: 10.18632/oncotarget.5505.
    • (2015) Oncotarget , vol.6 , pp. 36456-36471
    • Karpel-Massler, G.1    Ba, M.2    Shu, C.3    Halatsch, M.E.4    Westhoff, M.A.5    Bruce, J.N.6    Canoll, P.7    Siegelin, M.D.8
  • 36
    • 84957883015 scopus 로고    scopus 로고
    • First-In-Class Small Molecule ONC201 Induces DR5 and Cell Death in Tumor but Not Normal Cells to Provide a Wide Therapeutic Index as an Anti-Cancer Agent
    • Allen JE, Crowder R, El-Deiry WS. First-In-Class Small Molecule ONC201 Induces DR5 and Cell Death in Tumor but Not Normal Cells to Provide a Wide Therapeutic Index as an Anti-Cancer Agent. PLoS One. 2015; 10: e0143082. doi: 10.1371/journal.pone.0143082.
    • (2015) PLoS One , vol.10
    • Allen, J.E.1    Crowder, R.2    El-Deiry, W.S.3
  • 37
    • 1542685203 scopus 로고    scopus 로고
    • Anti-liver cancer activity of TNF-related apoptosis-inducing ligand gene and its bystander effects
    • He C, Lao WF, Hu XT, Xu XM, Xu J, Fang BL. Anti-liver cancer activity of TNF-related apoptosis-inducing ligand gene and its bystander effects. World J Gastroenterol. 2004; 10: 654-9.
    • (2004) World J Gastroenterol , vol.10 , pp. 654-659
    • He, C.1    Lao, W.F.2    Hu, X.T.3    Xu, X.M.4    Xu, J.5    Fang, B.L.6
  • 38
    • 0043130148 scopus 로고    scopus 로고
    • Cell to cell contact required for bystander effect of the TNF-related apoptosis-inducing ligand (TRAIL) gene
    • Huang X, Lin T, Gu J, Zhang L, Roth JA, Liu J, Fang B. Cell to cell contact required for bystander effect of the TNF-related apoptosis-inducing ligand (TRAIL) gene. Int J Oncol. 2003; 22: 1241-5.
    • (2003) Int J Oncol , vol.22 , pp. 1241-1245
    • Huang, X.1    Lin, T.2    Gu, J.3    Zhang, L.4    Roth, J.A.5    Liu, J.6    Fang, B.7
  • 39
    • 0035870294 scopus 로고    scopus 로고
    • Antitumor activity and bystander effects of the tumor necrosis factor-related apoptosisinducing ligand (TRAIL) gene
    • Kagawa S, He C, Gu J, Koch P, Rha SJ, Roth JA, Curley SA, Stephens LC, Fang B. Antitumor activity and bystander effects of the tumor necrosis factor-related apoptosisinducing ligand (TRAIL) gene. Cancer Res. 2001; 61: 3330-8.
    • (2001) Cancer Res , vol.61 , pp. 3330-3338
    • Kagawa, S.1    He, C.2    Gu, J.3    Koch, P.4    Rha, S.J.5    Roth, J.A.6    Curley, S.A.7    Stephens, L.C.8    Fang, B.9
  • 40
    • 84929220564 scopus 로고    scopus 로고
    • Genetic and Pharmacological Screens Converge in Identifying FLIP, BCL2, and IAP Proteins as Key Regulators of Sensitivity to the TRAIL-Inducing Anticancer Agent ONC201/TIC10
    • Allen JE, Prabhu VV, Talekar M, van den Heuvel AP, Lim B, Dicker DT, Fritz JL, Beck A, El-Deiry WS. Genetic and Pharmacological Screens Converge in Identifying FLIP, BCL2, and IAP Proteins as Key Regulators of Sensitivity to the TRAIL-Inducing Anticancer Agent ONC201/TIC10. Cancer Res. 2015; 75: 1668-74. doi: 10.1158/0008-5472. CAN-14-2356.
    • (2015) Cancer Res , vol.75 , pp. 1668-1674
    • Allen, J.E.1    Prabhu, V.V.2    Talekar, M.3    van den Heuvel, A.P.4    Lim, B.5    Dicker, D.T.6    Fritz, J.L.7    Beck, A.8    El-Deiry, W.S.9
  • 41
    • 84973137572 scopus 로고    scopus 로고
    • The preclinical evaluation of TIC10/ONC201 as an anti-pancreatic cancer agent
    • Zhang Q, Wang H, Ran L, Zhang Z, Jiang R. The preclinical evaluation of TIC10/ONC201 as an anti-pancreatic cancer agent. Biochem Biophys Res Commun. 2016; 476: 260-6. doi: 10.1016/j.bbrc.2016.05.106.
    • (2016) Biochem Biophys Res Commun , vol.476 , pp. 260-266
    • Zhang, Q.1    Wang, H.2    Ran, L.3    Zhang, Z.4    Jiang, R.5
  • 46
    • 34548409572 scopus 로고    scopus 로고
    • Clinical impact of bortezomib in frontline regimens for patients with multiple myeloma
    • Manochakian R, Miller KC, Chanan-Khan AA. Clinical impact of bortezomib in frontline regimens for patients with multiple myeloma. Oncologist. 2007; 12: 978-90. doi: 10.1634/theoncologist.12-8-978.
    • (2007) Oncologist , vol.12 , pp. 978-990
    • Manochakian, R.1    Miller, K.C.2    Chanan-Khan, A.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.