메뉴 건너뛰기




Volumn 14, Issue 15, 2015, Pages 2422-2428

ONC201 induces cell death in pediatric non- Hodgkin’s lymphoma cells

Author keywords

Cancer; Lymphoma; NHL; ONC201; TIC10; TRAIL

Indexed keywords

ANTINEOPLASTIC AGENT; BENDAMUSTINE; BIOLOGICAL MARKER; BORTEZOMIB; CYTARABINE; DEATH RECEPTOR 5; DOXORUBICIN; ONC 201; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; FUSED HETEROCYCLIC RINGS; TIC10 COMPOUND; TNFRSF21 PROTEIN, HUMAN; TNFSF10 PROTEIN, HUMAN; TUMOR MARKER; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 84943811613     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.1080/15384101.2015.1054086     Document Type: Article
Times cited : (27)

References (34)
  • 1
    • 77950624688 scopus 로고    scopus 로고
    • The World Health Organization (WHO) classification of tumors of the hematopoietic and lymphoid tissues: An overview with emphasis on the myeloid neoplasms
    • PMID: 19857474
    • Vardiman JW. The World Health Organization (WHO) classification of tumors of the hematopoietic and lymphoid tissues: an overview with emphasis on the myeloid neoplasms. Chem Biol Interact 2010; 184: 16-20; PMID: 19857474; http://dx. doi. org/10. 1016/j. cbi. 2009. 10. 009.
    • (2010) Chem Biol Interact , vol.184 , pp. 16-20
    • Vardiman, J.W.1
  • 2
    • 0034656999 scopus 로고    scopus 로고
    • The annual report to the nation on the status of cancer, 1973-1997, with a special section on colorectal cancer
    • PMID: 10820364
    • Ries LA, Wingo PA, Miller DS, Howe HL, Weir HK, Rosenberg HM, Vernon SW, Cronin K, Edwards BK. The annual report to the nation on the status of cancer, 1973-1997, with a special section on colorectal cancer. Cancer 2000; 88: 2398-424; PMID: 10820364; http://dx. doi. org/10. 1002/(SICI)1097-0142(20000515)88: 10%3 c2398:: AID-CNCR26%3e3. 0. CO; 2-I.
    • (2000) Cancer , vol.88 , pp. 2398-2424
    • Ries, L.A.1    Wingo, P.A.2    Miller, D.S.3    Howe, H.L.4    Weir, H.K.5    Rosenberg, H.M.6    Vernon, S.W.7    Cronin, K.8    Edwards, B.K.9
  • 3
    • 0030576183 scopus 로고    scopus 로고
    • Non-Hodgkin's lymphoma in childhood
    • PMID: 8606720
    • Sandlund JT, Downing JR, Crist WM. Non-Hodgkin's lymphoma in childhood. N Engl J Med 1996; 334: 1238-48; PMID: 8606720; http://dx. doi. org/10. 1056/NEJM199605093341906.
    • (1996) N Engl J Med , vol.334 , pp. 1238-1248
    • Sandlund, J.T.1    Downing, J.R.2    Crist, W.M.3
  • 4
    • 0036467427 scopus 로고    scopus 로고
    • Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
    • Cretney E, Takeda K, Yagita H, Glaccum M, Peschon JJ, Smyth MJ. Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice. J Immunol 2002; 168: 1356-61; http://dx. doi. org/10. 4049/jimmunol. 168. 3. 1356.
    • (2002) J Immunol , vol.168 , pp. 1356-1361
    • Cretney, E.1    Takeda, K.2    Yagita, H.3    Glaccum, M.4    Peschon, J.J.5    Smyth, M.J.6
  • 5
    • 65449152836 scopus 로고    scopus 로고
    • Following TRAIL's path in the immune system
    • PMID: 19476510
    • Falschlehner C, Schaefer U, Walczak H. Following TRAIL's path in the immune system. Immunology 2009; 127: 145-54; PMID: 19476510; http://dx. doi. org/10. 1111/j. 1365-2567. 2009. 03058. x.
    • (2009) Immunology , vol.127 , pp. 145-154
    • Falschlehner, C.1    Schaefer, U.2    Walczak, H.3
  • 6
    • 84872479262 scopus 로고    scopus 로고
    • Caspase-8 regulation of TRAIL-mediated cell death
    • PMID: 23070000
    • Crowder RN, El-Deiry WS. Caspase-8 regulation of TRAIL-mediated cell death. Exp Oncol 2012; 34: 160-4; PMID: 23070000.
    • (2012) Exp Oncol , vol.34 , pp. 160-164
    • Crowder, R.N.1    El-Deiry, W.S.2
  • 7
    • 24944458177 scopus 로고    scopus 로고
    • Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: Induction of apoptosis and enhancement of doxorubicin-and bortezomib-induced cell death
    • PMID: 16098063
    • Georgakis GV, Li Y, Humphreys R, Andreeff M, O'Brien S, Younes M, Carbone A, Albert V, Younes A. Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: induction of apoptosis and enhancement of doxorubicin-and bortezomib-induced cell death. Br J Haematol 2005; 130: 501-10; PMID: 16098063; http://dx. doi. org/10. 1111/j. 1365-2141. 2005. 05656. x.
    • (2005) Br J Haematol , vol.130 , pp. 501-510
    • Georgakis, G.V.1    Li, Y.2    Humphreys, R.3    Andreeff, M.4    O'Brien, S.5    Younes, M.6    Carbone, A.7    Albert, V.8    Younes, A.9
  • 9
    • 0346792725 scopus 로고    scopus 로고
    • TRAIL and apoptosis induction by TNF-family death receptors
    • PMID: 14634624
    • Wang S, El-Deiry WS. TRAIL and apoptosis induction by TNF-family death receptors. Oncogene 2003; 22: 8628-33; PMID: 14634624; http://dx. doi. org/10. 1038/sj. onc. 1207232.
    • (2003) Oncogene , vol.22 , pp. 8628-8633
    • Wang, S.1    El-Deiry, W.S.2
  • 10
    • 72449129475 scopus 로고    scopus 로고
    • Tumor Necrosis Factor-related apoptosis-inducing ligand (TRAIL) Receptor-1 and Receptor-2 agonists for cancer therapy
    • PMID: 19857186
    • Fox NL, Humphreys R, Luster TA, Klein J, Gallant G. Tumor Necrosis Factor-related apoptosis-inducing ligand (TRAIL) Receptor-1 and Receptor-2 agonists for cancer therapy. Expert Opin Biol Ther 2010; 10: 1-18; PMID: 19857186; http://dx. doi. org/10. 1517/14712590903319656.
    • (2010) Expert Opin Biol Ther , vol.10 , pp. 1-18
    • Fox, N.L.1    Humphreys, R.2    Luster, T.A.3    Klein, J.4    Gallant, G.5
  • 11
    • 77957045066 scopus 로고    scopus 로고
    • TRAIL receptor signaling and therapeutics
    • PMID: 20819019
    • Abdulghani J, El-Deiry WS. TRAIL receptor signaling and therapeutics. Exp Opin Ther Targets 2010; 14: 1091-108; PMID: 20819019; http://dx. doi. org/10. 1517/14728222. 2010. 519701.
    • (2010) Exp Opin Ther Targets , vol.14 , pp. 1091-1108
    • Abdulghani, J.1    El-Deiry, W.S.2
  • 12
    • 37049008917 scopus 로고    scopus 로고
    • Cooperation of the proapoptotic receptor agonist rhApo2L/TRAIL with the CD20 antibody rituximab against non-Hodgkin lymphoma xenografts
    • PMID: 17724141
    • Daniel D, Yang B, Lawrence DA, Totpal K, Balter I, Lee WP, Gogineni A, Cole MJ, Yee SF, Ross S, et al. Cooperation of the proapoptotic receptor agonist rhApo2L/TRAIL with the CD20 antibody rituximab against non-Hodgkin lymphoma xenografts. Blood 2007; 110: 4037-46; PMID: 17724141; http://dx. doi. org/10. 1182/blood-2007-02-076075.
    • (2007) Blood , vol.110 , pp. 4037-4046
    • Daniel, D.1    Yang, B.2    Lawrence, D.A.3    Totpal, K.4    Balter, I.5    Lee, W.P.6    Gogineni, A.7    Cole, M.J.8    Yee, S.F.9    Ross, S.10
  • 13
    • 0038007343 scopus 로고    scopus 로고
    • Regulation of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Burkitt's lymphoma cell lines
    • PMID: 12823346
    • Mouzakiti A, Packham G. Regulation of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Burkitt's lymphoma cell lines. Br J Haematol 2003; 122: 61-9; PMID: 12823346; http://dx. doi. org/10. 1046/j. 1365-2141. 2003. 04424. x.
    • (2003) Br J Haematol , vol.122 , pp. 61-69
    • Mouzakiti, A.1    Packham, G.2
  • 14
    • 0038622950 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas apoptosis in Burkitt's lymphomas with loss of multiple pro-apoptotic proteins
    • PMID: 12604406
    • Hussain A, Doucet JP, Gutierrez M, Ahmad M, Al-Hussein K, Capello D, Gaidano G, Bhatia K. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas apoptosis in Burkitt's lymphomas with loss of multiple pro-apoptotic proteins. Haematologica 2003; 88: 167-75; PMID: 12604406.
    • (2003) Haematologica , vol.88 , pp. 167-175
    • Hussain, A.1    Doucet, J.P.2    Gutierrez, M.3    Ahmad, M.4    Al-Hussein, K.5    Capello, D.6    Gaidano, G.7    Bhatia, K.8
  • 15
    • 0346157294 scopus 로고    scopus 로고
    • Induction of apoptosis in experimental human B cell lymphomas by conditional TRAIL-expressing T cells
    • PMID: 14647152
    • Ucur E, Mattern J, Wenger T, Okouoyo S, Schroth A, Debatin KM, Herr I. Induction of apoptosis in experimental human B cell lymphomas by conditional TRAIL-expressing T cells. Br J Cancer 2003; 89: 2155-62; PMID: 14647152; http://dx. doi. org/10. 1038/sj. bjc. 6601407.
    • (2003) Br J Cancer , vol.89 , pp. 2155-2162
    • Ucur, E.1    Mattern, J.2    Wenger, T.3    Okouoyo, S.4    Schroth, A.5    Debatin, K.M.6    Herr, I.7
  • 16
    • 84877941438 scopus 로고    scopus 로고
    • TRAIL-based therapeutic approaches for the treatment of pediatric malignancies
    • PMID: 23458616
    • Gasparini C, Vecchi Brumatti L, Monasta L, Zauli G. TRAIL-based therapeutic approaches for the treatment of pediatric malignancies. Curr Med Chem 2013; 20: 2254-71; PMID: 23458616; http://dx. doi. org/10. 2174/0929867311320170009.
    • (2013) Curr Med Chem , vol.20 , pp. 2254-2271
    • Gasparini, C.1    Vecchi Brumatti, L.2    Monasta, L.3    Zauli, G.4
  • 18
    • 77649157880 scopus 로고    scopus 로고
    • Development of immunohistochemistry assays to assess GALNT14 and FUT3/6 in clinical trials of dulanermin and drozitumab
    • PMID: 20179215
    • Stern HM, Padilla M, Wagner K, Amler L, Ashkenazi A. Development of immunohistochemistry assays to assess GALNT14 and FUT3/6 in clinical trials of dulanermin and drozitumab. Clin Cancer Res 2010; 16: 1587-96; PMID: 20179215; http://dx. doi. org/10. 1158/1078-0432. CCR-09-3108.
    • (2010) Clin Cancer Res , vol.16 , pp. 1587-1596
    • Stern, H.M.1    Padilla, M.2    Wagner, K.3    Amler, L.4    Ashkenazi, A.5
  • 22
    • 84874051647 scopus 로고    scopus 로고
    • Dual inactivation of Akt and ERK by TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction, and potent antitumor effects
    • PMID: 23390247
    • Allen JE, Krigsfeld G, Mayes PA, Patel L, Dicker DT, Patel AS, Dolloff NG, Messaris E, Scata KA, Wang W, et al. Dual inactivation of Akt and ERK by TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction, and potent antitumor effects. Sci Transl Med 2013; 5: 171ra17; PMID: 23390247; http://dx. doi. org/10. 1126/scitranslmed. 3004828.
    • (2013) Sci Transl Med , vol.5 , pp. 17
    • Allen, J.E.1    Krigsfeld, G.2    Mayes, P.A.3    Patel, L.4    Dicker, D.T.5    Patel, A.S.6    Dolloff, N.G.7    Messaris, E.8    Scata, K.A.9    Wang, W.10
  • 23
    • 84929220565 scopus 로고    scopus 로고
    • Small molecule ONC201/TIC10 targets chemotherapy-resistant colorectal cancer stem-like cells in an Akt/Foxo3a/TRAIL-dependent manner
    • Prabhu VV, Allen JE, Dicker DT, El-Deiry WS. Small molecule ONC201/TIC10 targets chemotherapy-resistant colorectal cancer stem-like cells in an Akt/Foxo3a/TRAIL-dependent manner. Cancer Res 2015; 75 (7): 1423-32; http://dx. doi. org/10. 1158/0008-5472. CAN-13-3451.
    • (2015) Cancer Res , vol.75 , Issue.7 , pp. 1423-1432
    • Prabhu, V.V.1    Allen, J.E.2    Dicker, D.T.3    El-Deiry, W.S.4
  • 24
    • 84892403042 scopus 로고    scopus 로고
    • The issue of low doses in radiation therapy and impact on radiation-induced secondary malignancies
    • PMID: 24257106
    • Chargari C, Cosset JM. [The issue of low doses in radiation therapy and impact on radiation-induced secondary malignancies]. Bull Cancer 2013; 100: 1333-42; PMID: 24257106.
    • (2013) Bull Cancer , vol.100 , pp. 1333-1342
    • Chargari, C.1    Cosset, J.M.2
  • 25
    • 84892669436 scopus 로고    scopus 로고
    • Controversies in the role of radiotherapy in the treatment of pediatric Hodgkin lymphoma
    • PMID: 23975267
    • Henry M, Savasan S. Controversies in the role of radiotherapy in the treatment of pediatric Hodgkin lymphoma. Ind J Pediatr 2013; 80: 863-9; PMID: 23975267; http://dx. doi. org/10. 1007/s12098-013-1106-8.
    • (2013) Ind J Pediatr , vol.80 , pp. 863-869
    • Henry, M.1    Savasan, S.2
  • 26
    • 4544242734 scopus 로고    scopus 로고
    • Death induction by recombinant nativeTRAIL and its prevention by a caspase 9 inhibitor in primary human esophageal epithelial cells
    • PMID: 15226295
    • Kim SH, Kim K, Kwagh JG, Dicker DT, Herlyn M, Rustgi AK, Chen Y, El-Deiry WS. Death induction by recombinant nativeTRAIL and its prevention by a caspase 9 inhibitor in primary human esophageal epithelial cells. J Biol Chem 2004; 279: 40044-52; PMID: 15226295; http://dx. doi. org/10. 1074/jbc. M404541200.
    • (2004) J Biol Chem , vol.279 , pp. 40044-40052
    • Kim, S.H.1    Kim, K.2    Kwagh, J.G.3    Dicker, D.T.4    Herlyn, M.5    Rustgi, A.K.6    Chen, Y.7    El-Deiry, W.S.8
  • 27
    • 84929220564 scopus 로고    scopus 로고
    • Genetic and pharmacological screens converge in identifying FLIP, BCL2 and IAP proteins as key regulators of sensitivity to the TRAIL-inducing anti-cancer agent ONC201/TIC10
    • Allen JE, Prabhu VV, Talekar M, van den Heuvel P, Lim B, Dicker DT, Fritz JL, Beck A, El-Deiry WS. Genetic and pharmacological screens converge in identifying FLIP, BCL2 and IAP proteins as key regulators of sensitivity to the TRAIL-inducing anti-cancer agent ONC201/TIC10. Cancer Res 2015; 75(8): 1668-74; http://dx. doi. org/10. 1158/0008-5472. CAN-14-2356.
    • (2015) Cancer Res , vol.75 , Issue.8 , pp. 1668-1674
    • Allen, J.E.1    Prabhu, V.V.2    Talekar, M.3    van den Heuvel, P.4    Lim, B.5    Dicker, D.T.6    Fritz, J.L.7    Beck, A.8    El-Deiry, W.S.9
  • 28
    • 0035839844 scopus 로고    scopus 로고
    • Translocations involving c-myc and c-myc function
    • PMID: 11607812
    • Boxer LM, Dang CV. Translocations involving c-myc and c-myc function. Oncogene 2001; 20: 5595-610; PMID: 11607812; http://dx. doi. org/10. 1038/sj. onc. 1204595.
    • (2001) Oncogene , vol.20 , pp. 5595-5610
    • Boxer, L.M.1    Dang, C.V.2
  • 29
    • 0037044731 scopus 로고    scopus 로고
    • c-Myc augments the apoptotic activity of cytosolic death receptor signaling proteins by engaging the mitochondrial apoptotic pathway
    • PMID: 12202489
    • Klefstrom J, Verschuren EW, Evan G. c-Myc augments the apoptotic activity of cytosolic death receptor signaling proteins by engaging the mitochondrial apoptotic pathway. J Biol Chem 2002; 277: 43224-32; PMID: 12202489; http://dx. doi. org/10. 1074/jbc. M206967200.
    • (2002) J Biol Chem , vol.277 , pp. 43224-43232
    • Klefstrom, J.1    Verschuren, E.W.2    Evan, G.3
  • 30
    • 4544253226 scopus 로고    scopus 로고
    • Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity
    • PMID: 15367674
    • Ricci MS, Jin Z, Dews M, Yu D, Thomas-Tikhonenko A, Dicker DT, El-Deiry WS. Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity. Mol Cell Biol 2004; 24: 8541-55; PMID: 15367674; http://dx. doi. org/10. 1128/MCB. 24. 19. 8541-8555. 2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 8541-8555
    • Ricci, M.S.1    Jin, Z.2    Dews, M.3    Yu, D.4    Thomas-Tikhonenko, A.5    Dicker, D.T.6    El-Deiry, W.S.7
  • 31
    • 0034306997 scopus 로고    scopus 로고
    • Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
    • PMID: 11018017
    • Sears R, Nuckolls F, Haura E, Taya Y, Tamai K, Nevins JR. Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Devel 2000; 14: 2501-14; PMID: 11018017; http://dx. doi. org/10. 1101/gad. 836800.
    • (2000) Genes Devel , vol.14 , pp. 2501-2514
    • Sears, R.1    Nuckolls, F.2    Haura, E.3    Taya, Y.4    Tamai, K.5    Nevins, J.R.6
  • 34
    • 74049159135 scopus 로고    scopus 로고
    • Combined effect of TNF-related apoptosis induced ligand and Ara-C in inducing apoptosis of HL-60 cells and its mechanism
    • Rao J, Zhang RY, Chen Y, Chen GA, Xiao CJ. [Combined effect of TNF-related apoptosis induced ligand and Ara-C in inducing apoptosis of HL-60 cells and its mechanism]. Zhongguo Shi Yan Xue Ye Xue Za Xhi 2008; 16: 510-5.
    • (2008) Zhongguo Shi Yan Xue Ye Xue Za Xhi , vol.16 , pp. 510-515
    • Rao, J.1    Zhang, R.Y.2    Chen, Y.3    Chen, G.A.4    Xiao, C.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.