Hypoxia-Inducible Factor-1α Mediates Increased Sympathoexcitation via Glutamatergic N-Methyl-d-Aspartate Receptors in the Paraventricular Nucleus of Rats with Chronic Heart Failure

Circulation: Heart Failure

Volumn 9, Issue 11, 2016, Pages

  Sharma, Neeru M ^a   Cunningham, Craig J ^a   Zheng, Hong ^a   Liu, Xuefei ^a   Patel, Kaushik P ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Hypoxia Inducible factor 1; myocardial ischemia; NMDA receptors; paraventricular nucleus

Indexed keywords

AMINO ACID RECEPTOR STIMULATING AGENT; HIF1A PROTEIN, RAT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYLASPARTIC ACID; NR1 NMDA RECEPTOR;

ADRENERGIC SYSTEM; ANIMAL; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CHRONIC DISEASE; DISEASE EXACERBATION; DISEASE MODEL; DRUG EFFECT; GENETICS; HEART FAILURE; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; HYPOXIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; METABOLISM; NERVE CELL; PATHOPHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; UPREGULATION;

ANIMALS; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; EXCITATORY AMINO ACID AGONISTS; HEART FAILURE; HYPOXIA; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; IN VITRO TECHNIQUES; MALE; N-METHYLASPARTATE; NEURONS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; SYMPATHETIC NERVOUS SYSTEM; UP-REGULATION;

EID: 84995777853     PISSN: 19413289     EISSN: 19413297     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.116.003423     Document Type: Article

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