Systemic TNF-α produces acute cognitive dysfunction and exaggerated sickness behavior when superimposed upon progressive neurodegeneration

Brain, Behavior, and Immunity

Volumn 59, Issue , 2017, Pages 233-244

  Hennessy, Edel ^a   Gormley, Shane ^a   Lopez Rodriguez, Ana Belen ^a   Murray, Caoimhe ^a   Murray, Carol ^a   Cunningham, Colm ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Behavior; Delirium; Dementia; Microglia; Sickness; Systemic inflammation; TNF

Indexed keywords

INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; RECOMBINANT TUMOR NECROSIS FACTOR; TAU PROTEIN; TUMOR NECROSIS FACTOR; CCL2 PROTEIN, MOUSE; CYTOKINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEGENERATION; BRAIN FUNCTION; BRAIN HOMOGENATE; COGNITIVE DEFECT; CONTROLLED STUDY; DEGENERATIVE DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC TRANSCRIPTION; HIPPOCAMPUS; HYPOTHALAMUS; HYPOTHERMIA; ILLNESS BEHAVIOR; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL NECROSIS; NERVOUS SYSTEM INFLAMMATION; NEUROPATHOLOGY; NONHUMAN; PHYSICAL INACTIVITY; PRION DISEASE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RNA TRANSLATION; SYNAPTIC TRANSMISSION; T-MAZE TEST; WEIGHT REDUCTION; WORKING MEMORY; ANIMAL; BLOOD; C57BL MOUSE; CHEMICALLY INDUCED; COMPLICATION; DRUG EFFECT; METABOLISM; MOTOR ACTIVITY; NERVE DEGENERATION; PSYCHOLOGY; PSYCHOMOTOR PERFORMANCE; SHORT TERM MEMORY;

ANIMALS; CHEMOKINE CCL2; COGNITIVE DYSFUNCTION; CYTOKINES; FEMALE; HIPPOCAMPUS; HYPOTHALAMUS; ILLNESS BEHAVIOR; MEMORY, SHORT-TERM; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; NERVE DEGENERATION; PRION DISEASES; PSYCHOMOTOR PERFORMANCE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84995614789     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2016.09.011     Document Type: Article

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