The AMP analog AICAR modulates the Treg/Th17 axis through enhancement of fatty acid oxidation

FASEB Journal

Volumn 30, Issue 11, 2016, Pages 3800-3809

  Gualdoni, Guido A ^a   Mayer, Katharina A ^a   Göschl, Lisa ^a,b   Boucheron, Nicole ^a   Ellmeier, Wilfried ^a   Zlabinger, Gerhard J ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

AMPK; Immunometabolism; Regulatory T cell; T cell; Th cell differentiation

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; DEOXYGLUCOSE; FATTY ACID; INTERLEUKIN 2; METFORMIN; 5 AMINO 4 IMIDAZOLECARBOXAMIDE; ADENOSINE PHOSPHATE; AICA RIBONUCLEOTIDE; ANTIDIABETIC AGENT; RIBONUCLEOTIDE;

ANIMAL CELL; ARTICLE; CELL EXPANSION; CELL FUNCTION; CELL LINE; CELL METABOLISM; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; FEMALE; IMMUNOMODULATION; IMMUNOSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; MITOCHONDRIAL BIOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; TH17 CELL; ANALOGS AND DERIVATIVES; ANIMAL; CELL CYCLE; CELL PROLIFERATION; DRUG EFFECTS; LIPID METABOLISM; METABOLISM; OXIDATION REDUCTION REACTION;

ADENOSINE MONOPHOSPHATE; AMINOIMIDAZOLE CARBOXAMIDE; ANIMALS; CELL CYCLE; CELL PROLIFERATION; FATTY ACIDS; HYPOGLYCEMIC AGENTS; INTERLEUKIN-2; LIPID METABOLISM; METABOLIC NETWORKS AND PATHWAYS; METFORMIN; OXIDATION-REDUCTION; RIBONUCLEOTIDES; T-LYMPHOCYTES, REGULATORY; TH17 CELLS;

EID: 84995554140     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.201600522R     Document Type: Article

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