Genetic and biochemical insights into the itaconate pathway of Ustilago maydis enable enhanced production

Metabolic Engineering

Volumn 38, Issue , 2016, Pages 427-435

  Geiser, Elena ^a,c   Przybilla, Sandra K ^a   Engel, Meike ^a   Kleineberg, Wiebke ^a,c   Büttner, Linda ^b   Sarikaya, Eda ^a   Hartog, Tim den ^a   Klankermayer, Jürgen ^a   Leitner, Walter ^a   Bölker, Michael ^b   Blank, Lars M ^a   Wierckx, Nick ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

2 hydroxyparaconate; Aspergillus terreus; Itaconate; Metabolic engineering; P450 monooxygenase; Secondary metabolites; Ustilago maydis

Indexed keywords

ASPERGILLUS; BIOTECHNOLOGY; FERMENTATION; GENES; METABOLIC ENGINEERING;

2-HYDROXYPARACONATE; ASPERGILLUS TERREUS; ITACONATE; MONOOXYGENASES; SECONDARY METABOLITES; USTILAGO MAYDIS;

METABOLITES;

2 HYDROXYPARACONATE; ACID; CYTOCHROME P450; CYTOCHROME P450 MONOOXYGENASE; ITACONIC ACID; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; CYTOCHROME P450 FAMILY 3; GAMMA BUTYROLACTONE; PARACONIC ACID; SUCCINIC ACID DERIVATIVE;

ARTICLE; BIOCHEMICAL ANALYSIS; BIOTECHNOLOGICAL PRODUCTION; CONTROLLED STUDY; CYP3 GENE; FED BATCH FERMENTATION; FUNGAL BIOMASS; FUNGAL GENE; FUNGAL STRAIN; FUNGUS CULTURE; GENE CLUSTER; GENE OVEREXPRESSION; NONHUMAN; PRIORITY JOURNAL; RIA1 GENE; USTILAGO MAYDIS; WILD TYPE; ANALOGS AND DERIVATIVES; BIOSYNTHESIS; CLASSIFICATION; GENE EXPRESSION REGULATION; GENETIC ENHANCEMENT; GENETICS; ISOLATION AND PURIFICATION; METABOLIC ENGINEERING; METABOLISM; PHYSIOLOGY; PROCEDURES; UPREGULATION; USTILAGO;

4-BUTYROLACTONE; BIOSYNTHETIC PATHWAYS; CYTOCHROME P450 FAMILY 3; GENE EXPRESSION REGULATION, FUNGAL; GENETIC ENHANCEMENT; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; SUCCINATES; UP-REGULATION; USTILAGO;

EID: 84995503664     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2016.10.006     Document Type: Article

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