Disruption of phacA, an Aspergillus nidulans gene encoding a novel cytochrome P450 monooxygenase catalyzing phenylacetate 2-hydroxylation, results in penicillin overproduction

Journal of Biological Chemistry

Volumn 274, Issue 21, 1999, Pages 14545-14550

  Mingot, José Manuel ^a   Peñalva, Miguel Angel ^a   Fernández Cañón, José Manuel ^a,b  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYPHENYLACETIC ACID; COMPLEMENTARY DNA; CYTOCHROME P450 ISOENZYME; HOMOGENTISIC ACID; PENICILLIN G; PHENYLACETIC ACID; PHENYLACETIC ACID DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ARTICLE; ASPERGILLUS NIDULANS; CATABOLISM; GENE DISRUPTION; GENETIC TRANSCRIPTION; HYDROXYLATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PENICILLIUM CHRYSOGENUM; PRIORITY JOURNAL;

ASPERGILLUS NIDULANS; CYTOCHROME P-450 ENZYME SYSTEM; FUNGAL PROTEINS; GENE EXPRESSION; HYDROXYLATION; MICROSOMES; MOLECULAR SEQUENCE DATA; OXYGENASES; PENICILLINS; PHENOTYPE; PHENYLACETATES;

EID: 0040559975     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.21.14545     Document Type: Article

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