Crystal structure of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida, a fumarase class II type cycloisomerase: Enzyme evolution in parallel pathways

Biochemistry

Volumn 43, Issue 32, 2004, Pages 10424-10434

  Yang, Jian ^a,c   Wang, Yi ^a,d   Woolridge, Elisa M ^a   Arora, Vandana ^a   Petsko, Gregory A ^a   Kozarich, John W ^b   Ringe, Dagmar ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b ACTIVX BIOSCIENCES INC   (United States)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

^d Experimental Station   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CRYSTAL STRUCTURE; ENZYMES; MICROORGANISMS; MONOMERS;

CHARGE RELAYS; HOMOTETRAMERS;

BIOCHEMISTRY;

ADENYLOSUCCINATE LYASE; FUMARATE HYDRATASE; ISOMERASE; MUCONIC ACID;

ADDITION REACTION; ARTICLE; BACILLUS; CRYSTAL STRUCTURE; ELIMINATION REACTION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STRUCTURE; LACTONIZATION; NEUROSPORA CRASSA; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS PUTIDA; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; EVOLUTION; FUMARATE HYDRATASE; INTRAMOLECULAR LYASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NEUROSPORA CRASSA; PROTEIN CONFORMATION; PSEUDOMONAS PUTIDA; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

EUKARYOTA; NEGIBACTERIA; NEUROSPORA; NEUROSPORA CRASSA; PROKARYOTA; PSEUDOMONAS; PSEUDOMONAS PUTIDA;

EID: 4043057880     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi036205c     Document Type: Article

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