Curcumin represses NLRP3 inflammasome activation via TLR4/MyD88/NF-κB and P2X7R signaling in PMA-induced macrophages

Frontiers in Pharmacology

Volumn 7, Issue OCT, 2016, Pages

  Kong, Fanqi ^a   Ye, Bozhi ^a   Cao, Jiatian ^b   Cai, Xueli ^a   Lin, Lu ^a   Huang, Shanjun ^a   Huang, Weijian ^a   Huang, Zhouqing ^a  

^a THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^b SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

Curcumin; Macrophages; NLRP3 inflammasome; P2X7R; TLR4 MyD88 NF

Indexed keywords

CRYOPYRIN; CURCUMIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MYELOID DIFFERENTIATION FACTOR 88; PHORBOL 13 ACETATE 12 MYRISTATE; PURINERGIC P2X7 RECEPTOR; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA;

APOPTOSIS; ARTICLE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; MACROPHAGE; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; UPREGULATION;

EID: 84995467656     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2016.00369     Document Type: Article

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