NLRP3 Inflammasome Mediates Aldosterone-Induced Vascular Damage

Circulation

Volumn 134, Issue 23, 2016, Pages 1866-1880

  Bruder Nascimento, Thiago ^a   Ferreira, Nathanne S ^a   Zanotto, Camila Z ^a   Ramalho, Fernanda ^a   Pequeno, Isabela O ^a   Olivon, Vania C ^a   Neves, Karla B ^a   Alves Lopes, Rheure ^a   Campos, Eduardo ^a   Silva, Carlos Alberto A ^b   Fazan, Rubens ^b   Carlos, Daniela ^c   Mestriner, Fabiola L ^a   Prado, Douglas ^a   Pereira, Felipe V ^d   Braga, Tarcio ^d   Luiz, Joao Paulo M ^a   Cau, Stefany B ^d   Elias, Paula C ^a   Moreira, Ayrton C ^a   Câmara, Niels O ^a   Zamboni, Dario S ^a   Alves Filho, Jose Carlos ^a   Tostes, Rita C ^a   more..

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Department of Physiology ^*  (Brazil)

^c Division of Endocrinology   (Brazil)

^d FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

aldosterone; immunology; inflammasomes; inflammation

Indexed keywords

ALDOSTERONE; CRYOPYRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; REACTIVE OXYGEN METABOLITE; ACETYLCHOLINE; ICAM1 PROTEIN, MOUSE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1 RECEPTOR; NIGERICIN; NLRP3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL INJURY; BONE MARROW DERIVED MACROPHAGE; CHIMERA; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; HYPERALDOSTERONISM; HYPERTENSION; IMMUNOCOMPETENT CELL; IN VITRO STUDY; INFLAMMATION; MALE; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; BLOOD; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; C57BL MOUSE; CHEMICALLY INDUCED; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; MACROPHAGE; MESENTERIC ARTERY; METABOLISM; PHYSIOLOGY; VASCULAR DISEASE;

ACETYLCHOLINE; ALDOSTERONE; ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CASPASE 1; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MALE; MESENTERIC ARTERIES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; NIGERICIN; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; REACTIVE OXYGEN SPECIES; RECEPTORS, INTERLEUKIN-1; SIGNAL TRANSDUCTION; VASCULAR DISEASES;

EID: 84994574757     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.116.024369     Document Type: Article

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