Biodistribution of antibody-MS2 viral capsid conjugates in breast cancer models

Molecular Pharmaceutics

Volumn 13, Issue 11, 2016, Pages 3764-3772

  Aanei, Ioana L ^a,b   Elsohly, Adel M ^a   Farkas, Michelle E ^a   Netirojjanakul, Chawita ^a   Regan, Melanie ^c   Taylor Murphy, Stephanie ^c   O'Neil, James P ^b   Seo, Youngho ^c   Francis, Matthew B ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

antibody targeting; bacteriophage MS2; bioconjugation; PET imaging; tumor targeting

Indexed keywords

ANTIBODY CONJUGATE; COPPER 64; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; ANTIBODY; CAPSID PROTEIN; NANOPARTICLE;

ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BREAST CANCER; CANCER CELL; CIRCULATION TIME; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONJUGATE; CONTROLLED STUDY; DRUG EFFICACY; DRUG TARGETING; ENTEROBACTERIA PHAGE MS2; EX VIVO STUDY; IMMUNOGENICITY; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; MOUSE; NANOIMAGING; NANOPHARMACEUTICS; NONHUMAN; OXIDATIVE COUPLING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SCINTILLATION COUNTING; TUMOR XENOGRAFT; VIRUS CAPSID; VIRUS LIKE AGENT; ANIMAL; BAGG ALBINO MOUSE; BREAST TUMOR; CHEMISTRY; CONFOCAL MICROSCOPY; FEMALE; FLOW CYTOMETRY; HUMAN; LEVIVIRUS; MCF-7 CELL LINE; METABOLISM; NUDE MOUSE; POSITRON EMISSION TOMOGRAPHY-COMPUTED TOMOGRAPHY;

ANIMALS; ANTIBODIES; BREAST NEOPLASMS; CAPSID; CAPSID PROTEINS; FEMALE; FLOW CYTOMETRY; HUMANS; LEVIVIRUS; MCF-7 CELLS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROSCOPY, CONFOCAL; NANOPARTICLES; POSITRON EMISSION TOMOGRAPHY COMPUTED TOMOGRAPHY;

EID: 84994537848     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.6b00566     Document Type: Article

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