메뉴 건너뛰기




Volumn 26, Issue 21, 2016, Pages R1161-R1166

Exploring Novel Methods for Modulating Tumor Blood Vessels in Cancer Treatment

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; HUMAN; NEOPLASM; PATHOLOGY; PATHOPHYSIOLOGY;

EID: 84994414361     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2016.09.043     Document Type: Review
Times cited : (86)

References (50)
  • 1
    • 33947732977 scopus 로고    scopus 로고
    • Angiogenesis: an organizing principle for drug discovery?
    • 1 Folkman, J., Angiogenesis: an organizing principle for drug discovery?. Nat. Rev. Drug Discov. 6 (2007), 273–286.
    • (2007) Nat. Rev. Drug Discov. , vol.6 , pp. 273-286
    • Folkman, J.1
  • 2
    • 77953988924 scopus 로고    scopus 로고
    • Targeting the tumour vasculature: insights from physiological angiogenesis
    • 2 Chung, A.S., Lee, J., Ferrara, N., Targeting the tumour vasculature: insights from physiological angiogenesis. Nat. Rev. Cancer 10 (2010), 505–514.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 505-514
    • Chung, A.S.1    Lee, J.2    Ferrara, N.3
  • 3
    • 72949119124 scopus 로고    scopus 로고
    • Integrins in cancer: biological implications and therapeutic opportunities
    • 3 Desgrosellier, J.S., Cheresh, D.A., Integrins in cancer: biological implications and therapeutic opportunities. Nat. Rev. Cancer 10 (2010), 9–22.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 9-22
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 4
    • 85013312416 scopus 로고
    • Tumor angiogenesis: therapeutic implications
    • 4 Folkman, J., Tumor angiogenesis: therapeutic implications. New Engl. J. Med. 285 (1971), 1182–1186.
    • (1971) New Engl. J. Med. , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 5
    • 69249100970 scopus 로고    scopus 로고
    • Current perspective: bevacizumab in colorectal cancer–a time for reappraisal?
    • 5 Okines, A., Cunningham, D., Current perspective: bevacizumab in colorectal cancer–a time for reappraisal?. Eur. J. Cancer 45 (2009), 2452–2461.
    • (2009) Eur. J. Cancer , vol.45 , pp. 2452-2461
    • Okines, A.1    Cunningham, D.2
  • 6
    • 34248173883 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200
    • 6 Giantonio, B.J., Catalano, P.J., Meropol, N.J., O'Dwyer, P.J., Mitchell, E.P., Alberts, S.R., Schwartz, M.A., Benson, A.B. 3rd, Cooperative, Eastern, Oncology Group Study, E., Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J. Clin. Oncol. 25 (2007), 1539–1544.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 1539-1544
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3    O'Dwyer, P.J.4    Mitchell, E.P.5    Alberts, S.R.6    Schwartz, M.A.7    Benson, A.B.8    Cooperative, E.9    Oncology Group Study, E.10
  • 7
    • 84903901969 scopus 로고    scopus 로고
    • Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions
    • 7 Vasudev, N.S., Reynolds, A.R., Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions. Angiogenesis 17 (2014), 471–494.
    • (2014) Angiogenesis , vol.17 , pp. 471-494
    • Vasudev, N.S.1    Reynolds, A.R.2
  • 8
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to anti-angiogenic therapy
    • 8 Bergers, G., Hanahan, D., Modes of resistance to anti-angiogenic therapy. Nat. Rev. Cancer 8 (2008), 592–603.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 9
    • 60649087564 scopus 로고    scopus 로고
    • Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
    • 9 Ebos, J.M., Lee, C.R., Cruz-Munoz, W., Bjarnason, G.A., Christensen, J.G., Kerbel, R.S., Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 15 (2009), 232–239.
    • (2009) Cancer Cell , vol.15 , pp. 232-239
    • Ebos, J.M.1    Lee, C.R.2    Cruz-Munoz, W.3    Bjarnason, G.A.4    Christensen, J.G.5    Kerbel, R.S.6
  • 11
    • 84912096468 scopus 로고    scopus 로고
    • Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia
    • 11 Jain, R.K., Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia. Cancer Cell 26 (2014), 605–622.
    • (2014) Cancer Cell , vol.26 , pp. 605-622
    • Jain, R.K.1
  • 12
    • 79957894276 scopus 로고    scopus 로고
    • Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
    • 12 Carmeliet, P., Jain, R.K., Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases. Nat. Rev. Drug Discov. 10 (2011), 417–427.
    • (2011) Nat. Rev. Drug Discov. , vol.10 , pp. 417-427
    • Carmeliet, P.1    Jain, R.K.2
  • 15
    • 14544280657 scopus 로고    scopus 로고
    • Vascular normalization: study examines how antiangiogenesis therapies work
    • 15 Webb, T., Vascular normalization: study examines how antiangiogenesis therapies work. J. Natl. Cancer Inst. 97 (2005), 336–337.
    • (2005) J. Natl. Cancer Inst. , vol.97 , pp. 336-337
    • Webb, T.1
  • 16
    • 43249095919 scopus 로고    scopus 로고
    • Tumor angiogenesis
    • 16 Kerbel, R.S., Tumor angiogenesis. New Engl. J. Med. 358 (2008), 2039–2049.
    • (2008) New Engl. J. Med. , vol.358 , pp. 2039-2049
    • Kerbel, R.S.1
  • 17
    • 84888328750 scopus 로고    scopus 로고
    • VEGF targets the tumour cell
    • 17 Goel, H.L., Mercurio, A.M., VEGF targets the tumour cell. Nat. Rev. Cancer 13 (2013), 871–882.
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 871-882
    • Goel, H.L.1    Mercurio, A.M.2
  • 18
    • 0036941610 scopus 로고    scopus 로고
    • The interaction of Neuropilin-1 and Neuropilin-2 with tyrosine-kinase receptors for VEGF
    • 18 Neufeld, G., Kessler, O., Herzog, Y., The interaction of Neuropilin-1 and Neuropilin-2 with tyrosine-kinase receptors for VEGF. Adv. Exp. Med. Biol. 515 (2002), 81–90.
    • (2002) Adv. Exp. Med. Biol. , vol.515 , pp. 81-90
    • Neufeld, G.1    Kessler, O.2    Herzog, Y.3
  • 19
    • 2442621619 scopus 로고    scopus 로고
    • Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
    • 19 Ferrara, N., Hillan, K.J., Gerber, H.P., Novotny, W., Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat. Rev. Drug Discov. 3 (2004), 391–400.
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 391-400
    • Ferrara, N.1    Hillan, K.J.2    Gerber, H.P.3    Novotny, W.4
  • 20
    • 84875699061 scopus 로고    scopus 로고
    • Strategies for improving the clinical benefit of antiangiogenic drug based therapies for breast cancer
    • 20 Kerbel, R.S., Strategies for improving the clinical benefit of antiangiogenic drug based therapies for breast cancer. J. Mammary Gland Biol. Neoplasia 17 (2012), 229–239.
    • (2012) J. Mammary Gland Biol. Neoplasia , vol.17 , pp. 229-239
    • Kerbel, R.S.1
  • 25
    • 84942103126 scopus 로고    scopus 로고
    • Angiogenesis revisited: an overlooked role of endothelial cell metabolism in vessel sprouting
    • 25 Vandekeere, S., Dewerchin, M., Carmeliet, P., Angiogenesis revisited: an overlooked role of endothelial cell metabolism in vessel sprouting. Microcirculation 22 (2015), 509–517.
    • (2015) Microcirculation , vol.22 , pp. 509-517
    • Vandekeere, S.1    Dewerchin, M.2    Carmeliet, P.3
  • 26
    • 84935082524 scopus 로고    scopus 로고
    • Endothelial cell metabolism in normal and diseased vasculature
    • 26 Eelen, G., de Zeeuw, P., Simons, M., Carmeliet, P., Endothelial cell metabolism in normal and diseased vasculature. Circ. Res. 116 (2015), 1231–1244.
    • (2015) Circ. Res. , vol.116 , pp. 1231-1244
    • Eelen, G.1    de Zeeuw, P.2    Simons, M.3    Carmeliet, P.4
  • 27
    • 85069238583 scopus 로고    scopus 로고
    • Endothelial cell metabolism: parallels and divergences with cancer cell metabolism
    • 27 Verdegem, D., Moens, S., Stapor, P., Carmeliet, P., Endothelial cell metabolism: parallels and divergences with cancer cell metabolism. Cancer Metab., 2, 2014, 19.
    • (2014) Cancer Metab. , vol.2 , pp. 19
    • Verdegem, D.1    Moens, S.2    Stapor, P.3    Carmeliet, P.4
  • 29
    • 30944446883 scopus 로고    scopus 로고
    • Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nature clinical practice
    • 29 Jain, R.K., Duda, D.G., Clark, J.W., Loeffler, J.S., Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nature clinical practice. Oncology 3 (2006), 24–40.
    • (2006) Oncology , vol.3 , pp. 24-40
    • Jain, R.K.1    Duda, D.G.2    Clark, J.W.3    Loeffler, J.S.4
  • 31
    • 78651461701 scopus 로고    scopus 로고
    • HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF
    • 31 Rolny, C., Mazzone, M., Tugues, S., Laoui, D., Johansson, I., Coulon, C., Squadrito, M.L., Segura, I., Li, X., Knevels, E., et al. HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF. Cancer Cell 19 (2011), 31–44.
    • (2011) Cancer Cell , vol.19 , pp. 31-44
    • Rolny, C.1    Mazzone, M.2    Tugues, S.3    Laoui, D.4    Johansson, I.5    Coulon, C.6    Squadrito, M.L.7    Segura, I.8    Li, X.9    Knevels, E.10
  • 32
    • 84855424339 scopus 로고    scopus 로고
    • Modulation of the tumor microvasculature by phosphoinositide-3 kinase inhibition increases doxorubicin delivery in vivo
    • 32 Qayum, N., Im, J., Stratford, M.R., Bernhard, E.J., McKenna, W.G., Muschel, R.J., Modulation of the tumor microvasculature by phosphoinositide-3 kinase inhibition increases doxorubicin delivery in vivo. Clin. Cancer. Res. 18 (2012), 161–169.
    • (2012) Clin. Cancer. Res. , vol.18 , pp. 161-169
    • Qayum, N.1    Im, J.2    Stratford, M.R.3    Bernhard, E.J.4    McKenna, W.G.5    Muschel, R.J.6
  • 34
    • 84901236251 scopus 로고    scopus 로고
    • Direct endothelial junction restoration results in significant tumor vascular normalization and metastasis inhibition in mice
    • 34 Agrawal, V., Maharjan, S., Kim, K., Kim, N.J., Son, J., Lee, K., Choi, H.J., Rho, S.S., Ahn, S., Won, M.H., et al. Direct endothelial junction restoration results in significant tumor vascular normalization and metastasis inhibition in mice. Oncotarget 5 (2014), 2761–2777.
    • (2014) Oncotarget , vol.5 , pp. 2761-2777
    • Agrawal, V.1    Maharjan, S.2    Kim, K.3    Kim, N.J.4    Son, J.5    Lee, K.6    Choi, H.J.7    Rho, S.S.8    Ahn, S.9    Won, M.H.10
  • 37
    • 40249089741 scopus 로고    scopus 로고
    • Provascular strategy: targeting functional adaptations of mature blood vessels in tumors to selectively influence the tumor vascular reactivity and improve cancer treatment
    • 37 Sonveaux, P., Provascular strategy: targeting functional adaptations of mature blood vessels in tumors to selectively influence the tumor vascular reactivity and improve cancer treatment. Radiother. Oncol. 86 (2008), 300–313.
    • (2008) Radiother. Oncol. , vol.86 , pp. 300-313
    • Sonveaux, P.1
  • 38
    • 0024427505 scopus 로고
    • Modification of tumour response by calcium antagonists in the SCVII/St tumour implanted at two different sites
    • 38 Wood, P.J., Hirst, D.G., Modification of tumour response by calcium antagonists in the SCVII/St tumour implanted at two different sites. Int. J. Radiat. Biol. 56 (1989), 355–367.
    • (1989) Int. J. Radiat. Biol. , vol.56 , pp. 355-367
    • Wood, P.J.1    Hirst, D.G.2
  • 39
    • 0020445088 scopus 로고
    • Effect of verapamil on malignant tissue blood flow in SMT-2A tumor-bearing rats
    • 39 Kaelin, W.G. Jr., Shrivastav, S., Shand, D.G., Jirtle, R.L., Effect of verapamil on malignant tissue blood flow in SMT-2A tumor-bearing rats. Cancer Res. 42 (1982), 3944–3949.
    • (1982) Cancer Res. , vol.42 , pp. 3944-3949
    • Kaelin, W.G.1    Shrivastav, S.2    Shand, D.G.3    Jirtle, R.L.4
  • 40
    • 0038235998 scopus 로고    scopus 로고
    • Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines
    • 40 Bergman, A.M., Pinedo, H.M., Talianidis, I., Veerman, G., Loves, W.J., van der Wilt, C.L., Peters, G.J., Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines. Br. J. Cancer 88 (2003), 1963–1970.
    • (2003) Br. J. Cancer , vol.88 , pp. 1963-1970
    • Bergman, A.M.1    Pinedo, H.M.2    Talianidis, I.3    Veerman, G.4    Loves, W.J.5    van der Wilt, C.L.6    Peters, G.J.7
  • 41
    • 0026720690 scopus 로고
    • Low-dose verapamil in middle-aged and elderly patients with angina pectoris: no evidence of increased susceptibility to the cardiac effects
    • 41 Ahmed, J.H., Elliott, H.L., Meredith, P.A., Reid, J.L., Low-dose verapamil in middle-aged and elderly patients with angina pectoris: no evidence of increased susceptibility to the cardiac effects. Cardiovasc. Drugs Ther. 6 (1992), 153–158.
    • (1992) Cardiovasc. Drugs Ther. , vol.6 , pp. 153-158
    • Ahmed, J.H.1    Elliott, H.L.2    Meredith, P.A.3    Reid, J.L.4
  • 43
    • 61649116978 scopus 로고    scopus 로고
    • Cilengitide induces cellular detachment and apoptosis in endothelial and glioma cells mediated by inhibition of FAK/src/AKT pathway
    • 43 Oliveira-Ferrer, L., Hauschild, J., Fiedler, W., Bokemeyer, C., Nippgen, J., Celik, I., Schuch, G., Cilengitide induces cellular detachment and apoptosis in endothelial and glioma cells mediated by inhibition of FAK/src/AKT pathway. J. Exp. Clin. Cancer Res., 27, 2008, 86.
    • (2008) J. Exp. Clin. Cancer Res. , vol.27 , pp. 86
    • Oliveira-Ferrer, L.1    Hauschild, J.2    Fiedler, W.3    Bokemeyer, C.4    Nippgen, J.5    Celik, I.6    Schuch, G.7
  • 44
    • 84908563697 scopus 로고    scopus 로고
    • Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial
    • 44 Stupp, R., Hegi, M.E., Gorlia, T., Erridge, S.C., Perry, J., Hong, Y.K., Aldape, K.D., Lhermitte, B., Pietsch, T., Grujicic, D., et al. Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol. 15 (2014), 1100–1108.
    • (2014) Lancet Oncol. , vol.15 , pp. 1100-1108
    • Stupp, R.1    Hegi, M.E.2    Gorlia, T.3    Erridge, S.C.4    Perry, J.5    Hong, Y.K.6    Aldape, K.D.7    Lhermitte, B.8    Pietsch, T.9    Grujicic, D.10
  • 46
    • 0036462584 scopus 로고    scopus 로고
    • Determinants of resistance to 2’,2’-difluorodeoxycytidine (gemcitabine)
    • 46 Bergman, A.M., Pinedo, H.M., Peters, G.J., Determinants of resistance to 2’,2’-difluorodeoxycytidine (gemcitabine). Drug Resis. Updates 5 (2002), 19–33.
    • (2002) Drug Resis. Updates , vol.5 , pp. 19-33
    • Bergman, A.M.1    Pinedo, H.M.2    Peters, G.J.3
  • 47
    • 0029967966 scopus 로고    scopus 로고
    • Forced expression of cytidine deaminase confers resistance to cytosine arabinoside and gemcitabine
    • 47 Neff, T., Blau, C.A., Forced expression of cytidine deaminase confers resistance to cytosine arabinoside and gemcitabine. Exp. Hematol. 24 (1996), 1340–1346.
    • (1996) Exp. Hematol. , vol.24 , pp. 1340-1346
    • Neff, T.1    Blau, C.A.2
  • 48
    • 84920933145 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor therapy in breast cancer: game over?
    • 48 Sledge, G.W., Anti-vascular endothelial growth factor therapy in breast cancer: game over?. J. Clin. Oncol. 33 (2015), 133–135.
    • (2015) J. Clin. Oncol. , vol.33 , pp. 133-135
    • Sledge, G.W.1
  • 49
    • 3042548695 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts
    • 49 Inai, T., Mancuso, M., Hashizume, H., Baffert, F., Haskell, A., Baluk, P., Hu-Lowe, D.D., Shalinsky, D.R., Thurston, G., Yancopoulos, G.D., et al. Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts. Am. J. Pathol. 165 (2004), 35–52.
    • (2004) Am. J. Pathol. , vol.165 , pp. 35-52
    • Inai, T.1    Mancuso, M.2    Hashizume, H.3    Baffert, F.4    Haskell, A.5    Baluk, P.6    Hu-Lowe, D.D.7    Shalinsky, D.R.8    Thurston, G.9    Yancopoulos, G.D.10
  • 50
    • 0031946469 scopus 로고    scopus 로고
    • Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factor
    • 50 Pham, C.D., Roberts, T.P., van Bruggen, N., Melnyk, O., Mann, J., Ferrara, N., Cohen, R.L., Brasch, R.C., Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factor. Cancer Invest. 16 (1998), 225–230.
    • (1998) Cancer Invest. , vol.16 , pp. 225-230
    • Pham, C.D.1    Roberts, T.P.2    van Bruggen, N.3    Melnyk, O.4    Mann, J.5    Ferrara, N.6    Cohen, R.L.7    Brasch, R.C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.