-
1
-
-
84920919864
-
Primary results of ROSE/TRIO-12, a randomized, placebo-controlled phase III trial evaluating the addition of ramucirumab to first-line docetaxel chemotherapy in metastatic breast cancer
-
Mackey JR, Ramos-Vazquez M, Lipatov O, et al: Primary results of ROSE/TRIO-12, a randomized, placebo-controlled phase III trial evaluating the addition of ramucirumab to first-line docetaxel chemotherapy in metastatic breast cancer. J Clin Oncol 33:141-148, 2015.
-
(2015)
J Clin Oncol
, vol.33
, pp. 141-148
-
-
Mackey, J.R.1
Ramos-Vazquez, M.2
Lipatov, O.3
-
2
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K, Wang M, Gralow J, et al: Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 357:2666-2676, 2007.
-
(2007)
N Engl J Med
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
-
3
-
-
77954700380
-
Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
-
Miles DW, Chan A, Dirix LY, et al: Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer. J Clin Oncol 28:3239-3247, 2010.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3239-3247
-
-
Miles, D.W.1
Chan, A.2
Dirix, L.Y.3
-
4
-
-
79953874259
-
RIBBON-1: Tandomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer
-
Robert NJ, Dieras V, Glaspy J, et al: TIBBON-1: Tandomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer. J Clin Oncol 29:1252-1260, 2011.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1252-1260
-
-
Robert, N.J.1
Dieras, V.2
Glaspy, J.3
-
5
-
-
33747481634
-
VEGF-targeting therapy for breast cancer
-
Sledge GW Jr: VEGF-targeting therapy for breast cancer. J Mammary Gland Biol Neoplasia 10:319-323, 2005.
-
(2005)
J Mammary Gland Biol Neoplasia
, vol.10
, pp. 319-323
-
-
Sledge, G.W.1
-
6
-
-
0036240896
-
Angiogenesis and antiangiogenic therapy
-
Sledge GW Jr, Miller KD: Angiogenesis and antiangiogenic therapy. Curr Probl Cancer 26:1-60, 2002.
-
(2002)
Curr Probl Cancer
, vol.26
, pp. 1-60
-
-
Sledge, G.W.1
Miller, K.D.2
-
7
-
-
0035870297
-
The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors
-
Sweeney CJ, Miller KD, Sissons SE, et al: The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors. Cancer Res 61:3369-3372, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 3369-3372
-
-
Sweeney, C.J.1
Miller, K.D.2
Sissons, S.E.3
-
8
-
-
0032930199
-
Paclitaxel (Taxol): An inhibitor of angiogenesis in a highly vascularized transgenic breast cancer
-
Lau DH, Xue L, Young LJ, et al: Paclitaxel (Taxol): An inhibitor of angiogenesis in a highly vascularized transgenic breast cancer. Cancer Biother Radiopharm 14:31-36, 1999.
-
(1999)
Cancer Biother Radiopharm
, vol.14
, pp. 31-36
-
-
Lau, D.H.1
Xue, L.2
Young, L.J.3
-
9
-
-
84887029479
-
First-line bevacizumab in combination with chemotherapy for HER2-negative metastatic breast cancer: Pooled and subgroup analyses of data from 2447 patients
-
Miles DW, Diéras V, Cortés J, et al: First-line bevacizumab in combination with chemotherapy for HER2-negative metastatic breast cancer: Pooled and subgroup analyses of data from 2447 patients. Ann Oncol 24:2773-2780, 2013.
-
(2013)
Ann Oncol
, vol.24
, pp. 2773-2780
-
-
Miles, D.W.1
Diéras, V.2
Cortés, J.3
-
10
-
-
84920917423
-
Bevacizumab (Bv) in the adjuvant treatment of HER2-negative breast cancer: Final results from Eastern Cooperative Oncology Group E5103
-
Miller K, O'Neill A, Dang C, et al: Bevacizumab (Bv) in the adjuvant treatment of HER2-negative breast cancer: Final results from Eastern Cooperative Oncology Group E5103. J Clin Oncol 32:5s, 2014 (suppl; abstr 500).
-
(2014)
J Clin Oncol
, vol.32
, Issue.5
-
-
Miller, K.1
O'Neill, A.2
Dang, C.3
-
11
-
-
84920930760
-
-
San Antonio Breast Cancer Symposium, San Antonio, TX, December 10-14
-
Slamon D, Swain S, Buyse M, et al: Primary results from BETH, a phase 3 controlled study of adjuvant chemotherapy and trastuzumab bevacizumab in patients with HER2-positive, node-positive or high risk node-negative breast cancer. San Antonio Breast Cancer Symposium, San Antonio, TX, December 10-14, 2013, pp S1-03.
-
(2013)
Primary Results from BETH, a Phase 3 Controlled Study of Adjuvant Chemotherapy and Trastuzumab Bevacizumab in Patients with HER2-positive, Node-positive or High Risk Node-negative Breast Cancer
, pp. S1-03
-
-
Slamon, D.1
Swain, S.2
Buyse, M.3
-
12
-
-
84883050174
-
Adjuvant bevacizumab-containing therapy in triple-negative breast cancer (BEATRICE): Primary results of a randomised, phase 3 trial
-
Cameron D, Brown J, Dent R, et al: Adjuvant bevacizumab-containing therapy in triple-negative breast cancer (BEATRICE): Primary results of a randomised, phase 3 trial. Lancet Oncol 14:933-942, 2013.
-
(2013)
Lancet Oncol
, vol.14
, pp. 933-942
-
-
Cameron, D.1
Brown, J.2
Dent, R.3
-
13
-
-
80051713290
-
Sunitinib plus paclitaxel versus bevacizumab plus paclitaxel for first-line treatment of patients with advanced breast cancer: A phase III, randomized, open-label trial
-
Robert NJ, Saleh MN, Paul D, et al: Sunitinib plus paclitaxel versus bevacizumab plus paclitaxel for first-line treatment of patients with advanced breast cancer: A phase III, randomized, open-label trial. Clin Breast Cancer 11:82-92, 2011.
-
(2011)
Clin Breast Cancer
, vol.11
, pp. 82-92
-
-
Robert, N.J.1
Saleh, M.N.2
Paul, D.3
-
14
-
-
84860625265
-
First-line treatment of advanced breast cancer with sunitinib in combination with docetaxel versus docetaxel alone: Tesults of a prospective, randomized phase III study
-
Bergh J, Bondarenko IM, Lichinitser MR, et al: First-line treatment of advanced breast cancer with sunitinib in combination with docetaxel versus docetaxel alone: Tesults of a prospective, randomized phase III study. J Clin Oncol 30:921-929, 2012.
-
(2012)
J Clin Oncol
, vol.30
, pp. 921-929
-
-
Bergh, J.1
Bondarenko, I.M.2
Lichinitser, M.R.3
-
15
-
-
84884126500
-
Phase III trial of sunitinib in combination with capecitabine versus capecitabine monotherapy for the treatment of patients with pretreated metastatic breast cancer
-
Crown JP, Diéras V, Staroslawska E, et al: Phase III trial of sunitinib in combination with capecitabine versus capecitabine monotherapy for the treatment of patients with pretreated metastatic breast cancer. J Clin Oncol 31:2870-2878, 2013.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2870-2878
-
-
Crown, J.P.1
Diéras, V.2
Staroslawska, E.3
-
16
-
-
77951296573
-
Phase III randomized trial of sunitinib versus capecitabine in patients with previously treated HER2-negative advanced breast cancer
-
Barrios CH, Liu MC, Lee SC, et al: Phase III randomized trial of sunitinib versus capecitabine in patients with previously treated HER2-negative advanced breast cancer. Breast Cancer Res Treat 121:121-131, 2010.
-
(2010)
Breast Cancer Res Treat
, vol.121
, pp. 121-131
-
-
Barrios, C.H.1
Liu, M.C.2
Lee, S.C.3
-
17
-
-
84892852372
-
Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): An international, randomised, multicentre, placebo-controlled, phase 3 trial
-
Fuchs CS, Tomasek J, Yong CJ, et al: Tamucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): An international, randomised, multicentre, placebo-controlled, phase 3 trial. Lancet 383:31-39, 2014.
-
(2014)
Lancet
, vol.383
, pp. 31-39
-
-
Fuchs, C.S.1
Tomasek, J.2
Yong, C.J.3
-
18
-
-
79959304867
-
Anti-vascular endothelial growth factor therapy for breast cancer: Can we pick the winners?
-
Schneider BP, Sledge GW Jr: Anti-vascular endothelial growth factor therapy for breast cancer: Can we pick the winners? J Clin Oncol 29:2444-2447, 2011.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2444-2447
-
-
Schneider, B.P.1
Sledge, G.W.2
-
19
-
-
53749093040
-
Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100
-
Schneider BP, Wang M, Radovich M, et al: Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100. J Clin Oncol 26:4672-4678, 2008.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4672-4678
-
-
Schneider, B.P.1
Wang, M.2
Radovich, M.3
-
20
-
-
84878979173
-
Predictive biomarkers for bevacizumab: Are we there yet?
-
Maru D, Venook AP, Ellis LM: Predictive biomarkers for bevacizumab: Are we there yet? Clin Cancer Res 19:2824-2827, 2013.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 2824-2827
-
-
Maru, D.1
Venook, A.P.2
Ellis, L.M.3
-
21
-
-
84907591274
-
Genetic variability of VEGF pathway genes in six randomized phase III trials assessing the addition of bevacizumab to standard therapy
-
epub ahead of print on July 11
-
deHaas S, Delmar P, Bansal AT, et al: Genetic variability of VEGF pathway genes in six randomized phase III trials assessing the addition of bevacizumab to standard therapy. Angiogenesis [epub ahead of print on July 11, 2014].
-
(2014)
Angiogenesis
-
-
De Haas, S.1
Delmar, P.2
Bansal, A.T.3
-
22
-
-
84877755368
-
Mechanisms of resistance to anti-angiogenesis therapies
-
Giuliano S, Pagès G: Mechanisms of resistance to anti-angiogenesis therapies. Biochimie 95:1110-1119, 2013.
-
(2013)
Biochimie
, vol.95
, pp. 1110-1119
-
-
Giuliano, S.1
Pagès, G.2
-
23
-
-
0031443206
-
A cancer therapy resistant to resistance
-
Kerbel, RS: A cancer therapy resistant to resistance. Nature 390:335-336, 1997.
-
(1997)
Nature
, vol.390
, pp. 335-336
-
-
Kerbel, R.S.1
-
24
-
-
84873328631
-
Bevacizumab in stage II-III colon cancer: 5-year update of the National Surgical Adjuvant Breast and Bowel Project C-08 trial
-
Allegra CJ, Yothers G, O'Connell MJ, et al: Bevacizumab in stage II-III colon cancer: 5-year update of the National Surgical Adjuvant Breast and Bowel Project C-08 trial. J Clin Oncol 31:359-364, 2013.
-
(2013)
J Clin Oncol
, vol.31
, pp. 359-364
-
-
Allegra, C.J.1
Yothers, G.2
O'Connell, M.J.3
-
25
-
-
84907023733
-
STORM: A phase III randomized, double-blind, placebo-controlled trial of adjuvant sorafenib after resection or ablation to prevent recurrence of hepatocellular carcinoma (HCC)
-
Bruix J, Takayama T, Mazzaferro V, et al: STORM: A phase III randomized, double-blind, placebo-controlled trial of adjuvant sorafenib after resection or ablation to prevent recurrence of hepatocellular carcinoma (HCC). J Clin Oncol 32:256s, 2014 (suppl; abstr 4006).
-
(2014)
J Clin Oncol
, vol.32
, pp. 256s
-
-
Bruix, J.1
Takayama, T.2
Mazzaferro, V.3
-
26
-
-
84901008789
-
Control of the immune response by pro-angiogenic factors
-
Voron T, Marcheteau E, Pernot S, et al: Control of the immune response by pro-angiogenic factors. Front Oncol 4:70, 2014.
-
(2014)
Front Oncol
, vol.4
, pp. 70
-
-
Voron, T.1
Marcheteau, E.2
Pernot, S.3
-
27
-
-
44249093051
-
The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients
-
Osada T, Chong G, Tansik R, et al: The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients. Cancer Immunol Immunother 57:1115-1124, 2008.
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 1115-1124
-
-
Osada, T.1
Chong, G.2
Tansik, R.3
-
28
-
-
79953647522
-
A novel function for programmed death ligand-1 regulation of angiogenesis
-
Jin Y, Chauhan SK, El Annan J, et al: A novel function for programmed death ligand-1 regulation of angiogenesis. Am J Pathol 178:1922-1929, 2011.
-
(2011)
Am J Pathol
, vol.178
, pp. 1922-1929
-
-
Jin, Y.1
Chauhan, S.K.2
El, A.J.3
|