Direct endothelial junction restoration results in significant tumor vascular normalization and metastasis inhibition in mice

Oncotarget

Volumn 5, Issue 9, 2014, Pages 2761-2777

  Agrawal, Vijayendra ^a   Maharjan, Sony ^a   Kim, Kyeojin ^b   Kim, Nam Jung ^c   Son, Jimin ^a   Lee, Keunho ^a   Choi, Hyun Jung ^a   Rho, Seung Sik ^a   Ahn, Sunjoo ^d   Won, Moo Ho ^e   Ha, Sang Jun ^a   Koh, Gou Young ^f   Kim, Young Myeong ^e   Suh, Young Ger ^b   Kwon, Young Guen ^a  

^a Yonsei University   (South Korea)

^b Seoul National University   (South Korea)

^c Kyung Hee University   (South Korea)

^d Korea Research Institute of Chemical Technology   (South Korea)

^e Kangwon National University   (South Korea)

^f Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Epithelial to mesenchymal transition; Hypoxia; Normalization; Sac 1004; Vascular permeability

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; OCCLUDIN; SAC 1004; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; CADHERIN; LEUKOCYTE ANTIGEN; MESSENGER RNA; SAC-1004; SAPONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER STEM CELL; CELL POPULATION; CELL PROLIFERATION; CHEMOSENSITIVITY; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GROWTH INHIBITION; HYPOXIA; LUNG METASTASIS; LYMPH NODE METASTASIS; MALE; METASTASIS INHIBITION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR VOLUME; VASCULAR TUMOR; ANIMAL; C57BL MOUSE; CARCINOMA, LEWIS LUNG; CELL MOTION; DIABETIC RETINOPATHY; DRUG EFFECTS; DRUG SCREENING; ENZYME IMMUNOASSAY; GENETICS; HELA CELL LINE; HUMAN; LUNG NEOPLASMS; MCF 7 CELL LINE; MELANOMA, EXPERIMENTAL; METABOLISM; NEOVASCULARIZATION, PATHOLOGIC; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECONDARY; TUMOR CELL CULTURE; VASCULAR ENDOTHELIUM; VASCULARIZATION; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD; APOPTOSIS; BLOTTING, WESTERN; CADHERINS; CARCINOMA, LEWIS LUNG; CELL MOVEMENT; CELL PROLIFERATION; DIABETIC RETINOPATHY; ENDOTHELIUM, VASCULAR; EPITHELIAL-MESENCHYMAL TRANSITION; HELA CELLS; HUMANS; IMMUNOENZYME TECHNIQUES; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; MCF-7 CELLS; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PATHOLOGIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SAPONINS; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84901236251     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1942     Document Type: Article

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