메뉴 건너뛰기




Volumn 39, Issue 11, 2016, Pages 1896-1901

Effect of serotonin transporter 5-HTTLPR polymorphism on gastrointestinal intolerance to metformin: A GoDARTS study

Author keywords

[No Author keywords available]

Indexed keywords

METFORMIN; ORGANIC CATION TRANSPORTER 1; SEROTONIN TRANSPORTER; ANTIDIABETIC AGENT; OCTAMER TRANSCRIPTION FACTOR 1; POU2F1 PROTEIN, HUMAN; SLC6A4 PROTEIN, HUMAN;

EID: 84994225731     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc16-0706     Document Type: Conference Paper
Times cited : (43)

References (29)
  • 1
    • 84919999219 scopus 로고    scopus 로고
    • Management of hyperglycemia in type 2 diabetes, 2015: A patient-centered approach: Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes
    • Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycemia in type 2 diabetes, 2015: A patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2015; 38:140-149
    • (2015) Diabetes Care , vol.38 , pp. 140-149
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3
  • 2
    • 0033578476 scopus 로고    scopus 로고
    • Pharmacologic therapy for type 2 diabetes mellitus
    • DeFronzo RA. Pharmacologic therapy for type 2 diabetes mellitus. Ann Intern Med 1999;131:281-303
    • (1999) Ann Intern Med , vol.131 , pp. 281-303
    • DeFronzo, R.A.1
  • 3
    • 0033973138 scopus 로고    scopus 로고
    • Effects of metformin on intestinal 5-hydroxytryptamine (5-HT) release and on 5-HT3 receptors
    • Cubeddu LX, Bönisch H,Göthert M, et al. Effects of metformin on intestinal 5-hydroxytryptamine (5-HT) release and on 5-HT3 receptors. Naunyn Schmiedebergs Arch Pharmacol 2000;361:85-91
    • (2000) Naunyn Schmiedebergs Arch Pharmacol , vol.361 , pp. 85-91
    • Cubeddu, L.X.1    Bönisch, H.2    Göthert, M.3
  • 4
    • 0345268644 scopus 로고    scopus 로고
    • Differential effects of metformin on bile salt absorption from the jejunum and ileum
    • Carter D, Howlett HC, Wiernsperger NF, Bailey CJ. Differential effects of metformin on bile salt absorption from the jejunum and ileum. Diabetes Obes Metab 2003;5:120-125
    • (2003) Diabetes Obes Metab , vol.5 , pp. 120-125
    • Carter, D.1    Howlett, H.C.2    Wiernsperger, N.F.3    Bailey, C.J.4
  • 5
    • 0035097211 scopus 로고    scopus 로고
    • Effect of metformin on glucagon-like peptide 1 (GLP-1) and leptin levels in obese nondiabetic subjects
    • Mannucci E, Ognibene A, Cremasco F, et al. Effect of metformin on glucagon-like peptide 1 (GLP-1) and leptin levels in obese nondiabetic subjects. Diabetes Care 2001;24:489-494
    • (2001) Diabetes Care , vol.24 , pp. 489-494
    • Mannucci, E.1    Ognibene, A.2    Cremasco, F.3
  • 6
    • 84949772416 scopus 로고    scopus 로고
    • Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
    • Forslund K, Hildebrand F, Nielsen T, et al.; MetaHIT consortium. Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. Nature 2015;528: 262-266
    • (2015) Nature , vol.528 , pp. 262-266
    • MetaHIT consortium1    Forslund, K.2    Hildebrand, F.3    Nielsen, T.4
  • 7
    • 0028158709 scopus 로고
    • Accumulation of metformin by tissues of the normal and diabetic mouse
    • Wilcock C, Bailey CJ. Accumulation of metformin by tissues of the normal and diabetic mouse. Xenobiotica 1994;24:49-57
    • (1994) Xenobiotica , vol.24 , pp. 49-57
    • Wilcock, C.1    Bailey, C.J.2
  • 8
    • 84964693539 scopus 로고    scopus 로고
    • Association of organic cation transporter 1 with intolerance to metformin in type 2 diabetes: A GoDARTS Study
    • Dujic T, Zhou K, Donnelly LA, Tavendale R, Palmer CN, Pearson ER. Association of organic cation transporter 1 with intolerance to metformin in type 2 diabetes: A GoDARTS Study. Diabetes 2015;64:1786-1793
    • (2015) Diabetes , vol.64 , pp. 1786-1793
    • Dujic, T.1    Zhou, K.2    Donnelly, L.A.3    Tavendale, R.4    Palmer, C.N.5    Pearson, E.R.6
  • 9
    • 27744454598 scopus 로고    scopus 로고
    • Drug specificity and intestinal membrane localization of human organic cation transporters (OCT)
    • Müller J, Lips KS, Metzner L, Neubert RH, Koepsell H, Brandsch M. Drug specificity and intestinal membrane localization of human organic cation transporters (OCT). Biochem Pharmacol 2005;70:1851-1860
    • (2005) Biochem Pharmacol , vol.70 , pp. 1851-1860
    • Müller, J.1    Lips, K.S.2    Metzner, L.3    Neubert, R.H.4    Koepsell, H.5    Brandsch, M.6
  • 10
    • 84880597876 scopus 로고    scopus 로고
    • Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes
    • Han TK, Everett RS, Proctor WR, et al. Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes. Mol Pharmacol 2013;84:182-189
    • (2013) Mol Pharmacol , vol.84 , pp. 182-189
    • Han, T.K.1    Everett, R.S.2    Proctor, W.R.3
  • 11
    • 84921464438 scopus 로고    scopus 로고
    • Four cation-selective transporters contribute to apical uptake and accumulation of metformin in Caco-2 cell monolayers
    • Han TK, Proctor WR, Costales CL, Cai H, Everett RS, Thakker DR. Four cation-selective transporters contribute to apical uptake and accumulation of metformin in Caco-2 cell monolayers. J Pharmacol Exp Ther 2015;352: 519-528
    • (2015) J Pharmacol Exp Ther , vol.352 , pp. 519-528
    • Han, T.K.1    Proctor, W.R.2    Costales, C.L.3    Cai, H.4    Everett, R.S.5    Thakker, D.R.6
  • 12
    • 84942502698 scopus 로고    scopus 로고
    • Prediction and validation of enzyme and transporter offtargets for metformin
    • Yee SW, Lin L, Merski M, et al. Prediction and validation of enzyme and transporter offtargets for metformin. J Pharmacokinet Pharmacodyn 2015;42:463-475
    • (2015) J Pharmacokinet Pharmacodyn , vol.42 , pp. 463-475
    • Yee, S.W.1    Lin, L.2    Merski, M.3
  • 13
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • Lesch KP, Bengel D, Heils A, et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 1996;274:1527-1531
    • (1996) Science , vol.274 , pp. 1527-1531
    • Lesch, K.P.1    Bengel, D.2    Heils, A.3
  • 14
    • 33646072813 scopus 로고    scopus 로고
    • Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder
    • Hu XZ, Lipsky RH, Zhu G, et al. Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Hum Genet 2006;78:815-826
    • (2006) Am J Hum Genet , vol.78 , pp. 815-826
    • Hu, X.Z.1    Lipsky, R.H.2    Zhu, G.3
  • 15
    • 84863455522 scopus 로고    scopus 로고
    • Prediction of serotonin transporter promoter polymorphismgenotypes from single nucleotide polymorphism arrays using machine learning methods
    • Lu AT, Bakker S, Janson E, Cichon S, Cantor RM, Ophoff RA. Prediction of serotonin transporter promoter polymorphismgenotypes from single nucleotide polymorphism arrays using machine learning methods. Psychiatr Genet 2012;22:182-188
    • (2012) Psychiatr Genet , vol.22 , pp. 182-188
    • Lu, A.T.1    Bakker, S.2    Janson, E.3    Cichon, S.4    Cantor, R.M.5    Ophoff, R.A.6
  • 16
    • 84961136385 scopus 로고    scopus 로고
    • Organic cation transporter 1 variants and gastrointestinal side effects ofmetformin in patients with Type 2 diabetes
    • Dujic T, Causevic A, Bego T, et al. Organic cation transporter 1 variants and gastrointestinal side effects ofmetformin in patients with Type 2 diabetes. Diabet Med 2016;33:511-514
    • (2016) Diabet Med , vol.33 , pp. 511-514
    • Dujic, T.1    Causevic, A.2    Bego, T.3
  • 17
    • 84893663496 scopus 로고    scopus 로고
    • The serotonin transporter gene polymorphism (5-HTTLPR) and irritable bowel syndrome: A meta-analysis of 25 studies
    • Zhang ZF, Duan ZJ,Wang LX, Yang D, Zhao G, Zhang L. The serotonin transporter gene polymorphism (5-HTTLPR) and irritable bowel syndrome: A meta-analysis of 25 studies. BMC Gastroenterol 2014;14:23
    • (2014) BMC Gastroenterol , vol.14 , pp. 23
    • Zhang, Z.F.1    Duan, Z.J.2    Wang, L.X.3    Yang, D.4    Zhao, G.5    Zhang, L.6
  • 18
    • 84897025156 scopus 로고    scopus 로고
    • SLC6A4 polymorphism, population genetics, and psychiatric traits
    • Gelernter J. SLC6A4 polymorphism, population genetics, and psychiatric traits. Hum Genet 2014;133:459-461
    • (2014) Hum Genet , vol.133 , pp. 459-461
    • Gelernter, J.1
  • 19
  • 20
    • 77951844279 scopus 로고    scopus 로고
    • Review and metaanalysis of antidepressant pharmacogenetic findings in major depressive disorder
    • Kato M, Serretti A. Review and metaanalysis of antidepressant pharmacogenetic findings in major depressive disorder. Mol Psychiatry 2010;15:473-500
    • (2010) Mol Psychiatry , vol.15 , pp. 473-500
    • Kato, M.1    Serretti, A.2
  • 21
    • 84881479285 scopus 로고    scopus 로고
    • Serotonin signalling in the gut-functions, dysfunctions and therapeutic targets
    • Mawe GM, Hoffman JM. Serotonin signalling in the gut-functions, dysfunctions and therapeutic targets. Nat Rev Gastroenterol Hepatol 2013;10:473-486
    • (2013) Nat Rev Gastroenterol Hepatol , vol.10 , pp. 473-486
    • Mawe, G.M.1    Hoffman, J.M.2
  • 22
    • 84901051205 scopus 로고    scopus 로고
    • Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake
    • Boxberger KH, Hagenbuch B, Lampe JN. Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake. Drug Metab Dispos 2014;42:990-995
    • (2014) Drug Metab Dispos , vol.42 , pp. 990-995
    • Boxberger, K.H.1    Hagenbuch, B.2    Lampe, J.N.3
  • 23
    • 34047170808 scopus 로고    scopus 로고
    • Regional distribution of solute carrier mRNA expression along the human intestinal tract
    • Meier Y, Eloranta JJ, Darimont J, et al. Regional distribution of solute carrier mRNA expression along the human intestinal tract. Drug Metab Dispos 2007;35:590-594
    • (2007) Drug Metab Dispos , vol.35 , pp. 590-594
    • Meier, Y.1    Eloranta, J.J.2    Darimont, J.3
  • 24
    • 47949130628 scopus 로고    scopus 로고
    • Mechanisms underlying saturable intestinal absorption of metformin
    • Proctor WR, Bourdet DL, Thakker DR. Mechanisms underlying saturable intestinal absorption of metformin. Drug Metab Dispos 2008;36:1650-1658
    • (2008) Drug Metab Dispos , vol.36 , pp. 1650-1658
    • Proctor, W.R.1    Bourdet, D.L.2    Thakker, D.R.3
  • 25
    • 34347374871 scopus 로고    scopus 로고
    • Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression
    • Hu XZ, Rush AJ, Charney D, et al. Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression. Arch Gen Psychiatry 2007;64:783-792
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 783-792
    • Hu, X.Z.1    Rush, A.J.2    Charney, D.3
  • 26
    • 33745866929 scopus 로고    scopus 로고
    • Recent advances on the importance of the serotonin transporter SERT in the rat intestine
    • Martel F. Recent advances on the importance of the serotonin transporter SERT in the rat intestine. Pharmacol Res 2006;54:73-76
    • (2006) Pharmacol Res , vol.54 , pp. 73-76
    • Martel, F.1
  • 27
    • 65549122835 scopus 로고    scopus 로고
    • Pharmacogenetics of antidepressant response: An update
    • Drago A, De Ronchi D, Serretti A. Pharmacogenetics of antidepressant response: an update. Hum Genomics 2009;3:257-274
    • (2009) Hum Genomics , vol.3 , pp. 257-274
    • Drago, A.1    De Ronchi, D.2    Serretti, A.3
  • 28
    • 0029885161 scopus 로고    scopus 로고
    • Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract
    • Wade PR, Chen J, Jaffe B, Kassem IS, Blakely RD, Gershon MD. Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract. J Neurosci 1996;16:2352-2364
    • (1996) J Neurosci , vol.16 , pp. 2352-2364
    • Wade, P.R.1    Chen, J.2    Jaffe, B.3    Kassem, I.S.4    Blakely, R.D.5    Gershon, M.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.