-
1
-
-
84949024194
-
ATM Localization and Heterochromatin Repair Depend on Direct Interaction of the 53BP1-BRCT2 Domain with γH2AX
-
Baldock, R.A., Day, M., Wilkinson, O.J., Cloney, R., Jeggo, P.A., Oliver, A.W., Watts, F.Z., Pearl, L.H., ATM Localization and Heterochromatin Repair Depend on Direct Interaction of the 53BP1-BRCT2 Domain with γH2AX. Cell Rep. 13 (2015), 2081–2089.
-
(2015)
Cell Rep.
, vol.13
, pp. 2081-2089
-
-
Baldock, R.A.1
Day, M.2
Wilkinson, O.J.3
Cloney, R.4
Jeggo, P.A.5
Oliver, A.W.6
Watts, F.Z.7
Pearl, L.H.8
-
2
-
-
79955502009
-
Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1
-
Bothmer, A., Robbiani, D.F., Di Virgilio, M., Bunting, S.F., Klein, I.A., Feldhahn, N., Barlow, J., Chen, H.-T., Bosque, D., Callen, E., et al. Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1. Mol. Cell 42 (2011), 319–329.
-
(2011)
Mol. Cell
, vol.42
, pp. 319-329
-
-
Bothmer, A.1
Robbiani, D.F.2
Di Virgilio, M.3
Bunting, S.F.4
Klein, I.A.5
Feldhahn, N.6
Barlow, J.7
Chen, H.-T.8
Bosque, D.9
Callen, E.10
-
3
-
-
33845666681
-
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
-
Botuyan, M.V., Lee, J., Ward, I.M., Kim, J.-E., Thompson, J.R., Chen, J., Mer, G., Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 127 (2006), 1361–1373.
-
(2006)
Cell
, vol.127
, pp. 1361-1373
-
-
Botuyan, M.V.1
Lee, J.2
Ward, I.M.3
Kim, J.-E.4
Thompson, J.R.5
Chen, J.6
Mer, G.7
-
4
-
-
77953291328
-
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
-
Bouwman, P., Aly, A., Escandell, J.M., Pieterse, M., Bartkova, J., van der Gulden, H., Hiddingh, S., Thanasoula, M., Kulkarni, A., Yang, Q., et al. 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat. Struct. Mol. Biol. 17 (2010), 688–695.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 688-695
-
-
Bouwman, P.1
Aly, A.2
Escandell, J.M.3
Pieterse, M.4
Bartkova, J.5
van der Gulden, H.6
Hiddingh, S.7
Thanasoula, M.8
Kulkarni, A.9
Yang, Q.10
-
5
-
-
31544457877
-
p53 ubiquitination: Mdm2 and beyond
-
Brooks, C.L., Gu, W., p53 ubiquitination: Mdm2 and beyond. Mol. Cell 21 (2006), 307–315.
-
(2006)
Mol. Cell
, vol.21
, pp. 307-315
-
-
Brooks, C.L.1
Gu, W.2
-
6
-
-
33646343474
-
An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors
-
Brummelkamp, T.R., Fabius, A.W.M., Mullenders, J., Madiredjo, M., Velds, A., Kerkhoven, R.M., Bernards, R., Beijersbergen, R.L., An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors. Nat. Chem. Biol. 2 (2006), 202–206.
-
(2006)
Nat. Chem. Biol.
, vol.2
, pp. 202-206
-
-
Brummelkamp, T.R.1
Fabius, A.W.M.2
Mullenders, J.3
Madiredjo, M.4
Velds, A.5
Kerkhoven, R.M.6
Bernards, R.7
Beijersbergen, R.L.8
-
7
-
-
77950958141
-
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
-
Bunting, S.F., Callén, E., Wong, N., Chen, H.-T., Polato, F., Gunn, A., Bothmer, A., Feldhahn, N., Fernandez-Capetillo, O., Cao, L., et al. 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell 141 (2010), 243–254.
-
(2010)
Cell
, vol.141
, pp. 243-254
-
-
Bunting, S.F.1
Callén, E.2
Wong, N.3
Chen, H.-T.4
Polato, F.5
Gunn, A.6
Bothmer, A.7
Feldhahn, N.8
Fernandez-Capetillo, O.9
Cao, L.10
-
8
-
-
84878893538
-
53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions
-
Callen, E., Di Virgilio, M., Kruhlak, M.J., Nieto-Soler, M., Wong, N., Chen, H.-T., Faryabi, R.B., Polato, F., Santos, M., Starnes, L.M., et al. 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions. Cell 153 (2013), 1266–1280.
-
(2013)
Cell
, vol.153
, pp. 1266-1280
-
-
Callen, E.1
Di Virgilio, M.2
Kruhlak, M.J.3
Nieto-Soler, M.4
Wong, N.5
Chen, H.-T.6
Faryabi, R.B.7
Polato, F.8
Santos, M.9
Starnes, L.M.10
-
9
-
-
84905638808
-
Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor
-
Carr, S.M., Munro, S., Zalmas, L.-P., Fedorov, O., Johansson, C., Krojer, T., Sagum, C.A., Bedford, M.T., Oppermann, U., La Thangue, N.B., Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor. Proc. Natl. Acad. Sci. USA 111 (2014), 11341–11346.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 11341-11346
-
-
Carr, S.M.1
Munro, S.2
Zalmas, L.-P.3
Fedorov, O.4
Johansson, C.5
Krojer, T.6
Sagum, C.A.7
Bedford, M.T.8
Oppermann, U.9
La Thangue, N.B.10
-
10
-
-
78149284014
-
TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint
-
Cescutti, R., Negrini, S., Kohzaki, M., Halazonetis, T.D., TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint. EMBO J. 29 (2010), 3723–3732.
-
(2010)
EMBO J.
, vol.29
, pp. 3723-3732
-
-
Cescutti, R.1
Negrini, S.2
Kohzaki, M.3
Halazonetis, T.D.4
-
11
-
-
84865364870
-
Playing the end game: DNA double-strand break repair pathway choice
-
Chapman, J.R., Taylor, M.R.G., Boulton, S.J., Playing the end game: DNA double-strand break repair pathway choice. Mol. Cell 47 (2012), 497–510.
-
(2012)
Mol. Cell
, vol.47
, pp. 497-510
-
-
Chapman, J.R.1
Taylor, M.R.G.2
Boulton, S.J.3
-
12
-
-
84876855215
-
RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection
-
Chapman, J.R., Barral, P., Vannier, J.-B., Borel, V., Steger, M., Tomas-Loba, A., Sartori, A.A., Adams, I.R., Batista, F.D., Boulton, S.J., RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection. Mol. Cell 49 (2013), 858–871.
-
(2013)
Mol. Cell
, vol.49
, pp. 858-871
-
-
Chapman, J.R.1
Barral, P.2
Vannier, J.-B.3
Borel, V.4
Steger, M.5
Tomas-Loba, A.6
Sartori, A.A.7
Adams, I.R.8
Batista, F.D.9
Boulton, S.J.10
-
13
-
-
1842431904
-
Tumour suppression: disruption of HAUSP gene stabilizes p53
-
Cummins, J.M., Rago, C., Kohli, M., Kinzler, K.W., Lengauer, C., Vogelstein, B., Tumour suppression: disruption of HAUSP gene stabilizes p53. Nature 428 (2004), 1–486.
-
(2004)
Nature
, vol.428
, pp. 1-486
-
-
Cummins, J.M.1
Rago, C.2
Kohli, M.3
Kinzler, K.W.4
Lengauer, C.5
Vogelstein, B.6
-
14
-
-
0037099666
-
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor
-
Derbyshire, D.J., Basu, B.P., Serpell, L.C., Joo, W.S., Date, T., Iwabuchi, K., Doherty, A.J., Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor. EMBO J. 21 (2002), 3863–3872.
-
(2002)
EMBO J.
, vol.21
, pp. 3863-3872
-
-
Derbyshire, D.J.1
Basu, B.P.2
Serpell, L.C.3
Joo, W.S.4
Date, T.5
Iwabuchi, K.6
Doherty, A.J.7
-
15
-
-
84873526612
-
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching
-
Di Virgilio, M., Callen, E., Yamane, A., Zhang, W., Jankovic, M., Gitlin, A.D., Feldhahn, N., Resch, W., Oliveira, T.Y., Chait, B.T., et al. Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching. Science 339 (2013), 711–715.
-
(2013)
Science
, vol.339
, pp. 711-715
-
-
Di Virgilio, M.1
Callen, E.2
Yamane, A.3
Zhang, W.4
Jankovic, M.5
Gitlin, A.D.6
Feldhahn, N.7
Resch, W.8
Oliveira, T.Y.9
Chait, B.T.10
-
16
-
-
57049124828
-
53BP1 facilitates long-range DNA end-joining during V(D)J recombination
-
Difilippantonio, S., Gapud, E., Wong, N., Huang, C.-Y., Mahowald, G., Chen, H.-T., Kruhlak, M.J., Callen, E., Livak, F., Nussenzweig, M.C., et al. 53BP1 facilitates long-range DNA end-joining during V(D)J recombination. Nature 456 (2008), 529–533.
-
(2008)
Nature
, vol.456
, pp. 529-533
-
-
Difilippantonio, S.1
Gapud, E.2
Wong, N.3
Huang, C.-Y.4
Mahowald, G.5
Chen, H.-T.6
Kruhlak, M.J.7
Callen, E.8
Livak, F.9
Nussenzweig, M.C.10
-
17
-
-
34250847654
-
CDK8 is a stimulus-specific positive coregulator of p53 target genes
-
Donner, A.J., Szostek, S., Hoover, J.M., Espinosa, J.M., CDK8 is a stimulus-specific positive coregulator of p53 target genes. Mol. Cell 27 (2007), 121–133.
-
(2007)
Mol. Cell
, vol.27
, pp. 121-133
-
-
Donner, A.J.1
Szostek, S.2
Hoover, J.M.3
Espinosa, J.M.4
-
18
-
-
0028220204
-
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
-
Dulić, V., Kaufmann, W.K., Wilson, S.J., Tlsty, T.D., Lees, E., Harper, J.W., Elledge, S.J., Reed, S.I., p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76 (1994), 1013–1023.
-
(1994)
Cell
, vol.76
, pp. 1013-1023
-
-
Dulić, V.1
Kaufmann, W.K.2
Wilson, S.J.3
Tlsty, T.D.4
Lees, E.5
Harper, J.W.6
Elledge, S.J.7
Reed, S.I.8
-
19
-
-
84876877091
-
A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice
-
Escribano-Díaz, C., Orthwein, A., Fradet-Turcotte, A., Xing, M., Young, J.T.F., Tkáč, J., Cook, M.A., Rosebrock, A.P., Munro, M., Canny, M.D., et al. A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice. Mol. Cell 49 (2013), 872–883.
-
(2013)
Mol. Cell
, vol.49
, pp. 872-883
-
-
Escribano-Díaz, C.1
Orthwein, A.2
Fradet-Turcotte, A.3
Xing, M.4
Young, J.T.F.5
Tkáč, J.6
Cook, M.A.7
Rosebrock, A.P.8
Munro, M.9
Canny, M.D.10
-
20
-
-
84879888213
-
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
-
Fradet-Turcotte, A., Canny, M.D., Escribano-Díaz, C., Orthwein, A., Leung, C.C.Y., Huang, H., Landry, M.-C., Kitevski-LeBlanc, J., Noordermeer, S.M., Sicheri, F., Durocher, D., 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark. Nature 499 (2013), 50–54.
-
(2013)
Nature
, vol.499
, pp. 50-54
-
-
Fradet-Turcotte, A.1
Canny, M.D.2
Escribano-Díaz, C.3
Orthwein, A.4
Leung, C.C.Y.5
Huang, H.6
Landry, M.-C.7
Kitevski-LeBlanc, J.8
Noordermeer, S.M.9
Sicheri, F.10
Durocher, D.11
-
21
-
-
34548513035
-
p53 is regulated by the lysine demethylase LSD1
-
Huang, J., Sengupta, R., Espejo, A.B., Lee, M.G., Dorsey, J.A., Richter, M., Opravil, S., Shiekhattar, R., Bedford, M.T., Jenuwein, T., Berger, S.L., p53 is regulated by the lysine demethylase LSD1. Nature 449 (2007), 105–108.
-
(2007)
Nature
, vol.449
, pp. 105-108
-
-
Huang, J.1
Sengupta, R.2
Espejo, A.B.3
Lee, M.G.4
Dorsey, J.A.5
Richter, M.6
Opravil, S.7
Shiekhattar, R.8
Bedford, M.T.9
Jenuwein, T.10
Berger, S.L.11
-
22
-
-
0028242909
-
Two cellular proteins that bind to wild-type but not mutant p53
-
Iwabuchi, K., Bartel, P.L., Li, B., Marraccino, R., Fields, S., Two cellular proteins that bind to wild-type but not mutant p53. Proc. Natl. Acad. Sci. USA 91 (1994), 6098–6102.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 6098-6102
-
-
Iwabuchi, K.1
Bartel, P.L.2
Li, B.3
Marraccino, R.4
Fields, S.5
-
23
-
-
0032475885
-
Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2
-
Iwabuchi, K., Li, B., Massa, H.F., Trask, B.J., Date, T., Fields, S., Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2. J. Biol. Chem. 273 (1998), 26061–26068.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 26061-26068
-
-
Iwabuchi, K.1
Li, B.2
Massa, H.F.3
Trask, B.J.4
Date, T.5
Fields, S.6
-
24
-
-
33746166746
-
53BP1 contributes to survival of cells irradiated with X-ray during G1 without Ku70 or Artemis
-
Iwabuchi, K., Hashimoto, M., Matsui, T., Kurihara, T., Shimizu, H., Adachi, N., Ishiai, M., Yamamoto, K., Tauchi, H., Takata, M., et al. 53BP1 contributes to survival of cells irradiated with X-ray during G1 without Ku70 or Artemis. Genes Cells 11 (2006), 935–948.
-
(2006)
Genes Cells
, vol.11
, pp. 935-948
-
-
Iwabuchi, K.1
Hashimoto, M.2
Matsui, T.3
Kurihara, T.4
Shimizu, H.5
Adachi, N.6
Ishiai, M.7
Yamamoto, K.8
Tauchi, H.9
Takata, M.10
-
25
-
-
0036500691
-
Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure
-
Joo, W.S., Jeffrey, P.D., Cantor, S.B., Finnin, M.S., Livingston, D.M., Pavletich, N.P., Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev. 16 (2002), 583–593.
-
(2002)
Genes Dev.
, vol.16
, pp. 583-593
-
-
Joo, W.S.1
Jeffrey, P.D.2
Cantor, S.B.3
Finnin, M.S.4
Livingston, D.M.5
Pavletich, N.P.6
-
26
-
-
58049203867
-
Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling
-
Kachirskaia, I., Shi, X., Yamaguchi, H., Tanoue, K., Wen, H., Wang, E.W., Appella, E., Gozani, O., Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling. J. Biol. Chem. 283 (2008), 34660–34666.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 34660-34666
-
-
Kachirskaia, I.1
Shi, X.2
Yamaguchi, H.3
Tanoue, K.4
Wen, H.5
Wang, E.W.6
Appella, E.7
Gozani, O.8
-
27
-
-
84941876588
-
Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage response
-
Kleiner, R.E., Verma, P., Molloy, K.R., Chait, B.T., Kapoor, T.M., Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage response. Nat. Chem. Biol. 11 (2015), 807–814.
-
(2015)
Nat. Chem. Biol.
, vol.11
, pp. 807-814
-
-
Kleiner, R.E.1
Verma, P.2
Molloy, K.R.3
Chait, B.T.4
Kapoor, T.M.5
-
28
-
-
84899880562
-
USP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism
-
Knobel, P.A., Belotserkovskaya, R., Galanty, Y., Schmidt, C.K., Jackson, S.P., Stracker, T.H., USP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism. Mol. Cell. Biol. 34 (2014), 2062–2074.
-
(2014)
Mol. Cell. Biol.
, vol.34
, pp. 2062-2074
-
-
Knobel, P.A.1
Belotserkovskaya, R.2
Galanty, Y.3
Schmidt, C.K.4
Jackson, S.P.5
Stracker, T.H.6
-
29
-
-
84903715003
-
Transient activation of p53 in G2 phase is sufficient to induce senescence
-
Krenning, L., Feringa, F.M., Shaltiel, I.A., van den Berg, J., Medema, R.H., Transient activation of p53 in G2 phase is sufficient to induce senescence. Mol. Cell 55 (2014), 59–72.
-
(2014)
Mol. Cell
, vol.55
, pp. 59-72
-
-
Krenning, L.1
Feringa, F.M.2
Shaltiel, I.A.3
van den Berg, J.4
Medema, R.H.5
-
30
-
-
65549120715
-
Modes of p53 regulation
-
Kruse, J.-P., Gu, W., Modes of p53 regulation. Cell 137 (2009), 609–622.
-
(2009)
Cell
, vol.137
, pp. 609-622
-
-
Kruse, J.-P.1
Gu, W.2
-
31
-
-
76349099135
-
53BP1 promotes ATM activity through direct interactions with the MRN complex
-
Lee, J.-H., Goodarzi, A.A., Jeggo, P.A., Paull, T.T., 53BP1 promotes ATM activity through direct interactions with the MRN complex. EMBO J. 29 (2010), 574–585.
-
(2010)
EMBO J.
, vol.29
, pp. 574-585
-
-
Lee, J.-H.1
Goodarzi, A.A.2
Jeggo, P.A.3
Paull, T.T.4
-
32
-
-
0037061508
-
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
-
Li, M., Chen, D., Shiloh, A., Luo, J., Nikolaev, A.Y., Qin, J., Gu, W., Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature 416 (2002), 648–653.
-
(2002)
Nature
, vol.416
, pp. 648-653
-
-
Li, M.1
Chen, D.2
Shiloh, A.3
Luo, J.4
Nikolaev, A.Y.5
Qin, J.6
Gu, W.7
-
33
-
-
1842421376
-
A dynamic role of HAUSP in the p53-Mdm2 pathway
-
Li, M., Brooks, C.L., Kon, N., Gu, W., A dynamic role of HAUSP in the p53-Mdm2 pathway. Mol. Cell 13 (2004), 879–886.
-
(2004)
Mol. Cell
, vol.13
, pp. 879-886
-
-
Li, M.1
Brooks, C.L.2
Kon, N.3
Gu, W.4
-
34
-
-
0031869669
-
No requirement for V(D)J recombination in p53-deficient thymic lymphoma
-
Liao, M.J., Zhang, X.X., Hill, R., Gao, J., Qumsiyeh, M.B., Nichols, W., Van Dyke, T., No requirement for V(D)J recombination in p53-deficient thymic lymphoma. Mol. Cell. Biol. 18 (1998), 3495–3501.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3495-3501
-
-
Liao, M.J.1
Zhang, X.X.2
Hill, R.3
Gao, J.4
Qumsiyeh, M.B.5
Nichols, W.6
Van Dyke, T.7
-
35
-
-
84873458032
-
Role of 53BP1 oligomerization in regulating double-strand break repair
-
Lottersberger, F., Bothmer, A., Robbiani, D.F., Nussenzweig, M.C., de Lange, T., Role of 53BP1 oligomerization in regulating double-strand break repair. Proc. Natl. Acad. Sci. USA 110 (2013), 2146–2151.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 2146-2151
-
-
Lottersberger, F.1
Bothmer, A.2
Robbiani, D.F.3
Nussenzweig, M.C.4
de Lange, T.5
-
36
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe, S.W., Schmitt, E.M., Smith, S.W., Osborne, B.A., Jacks, T., p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362 (1993), 847–849.
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
37
-
-
2442707746
-
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination
-
Manis, J.P., Morales, J.C., Xia, Z., Kutok, J.L., Alt, F.W., Carpenter, P.B., 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination. Nat. Immunol. 5 (2004), 481–487.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 481-487
-
-
Manis, J.P.1
Morales, J.C.2
Xia, Z.3
Kutok, J.L.4
Alt, F.W.5
Carpenter, P.B.6
-
38
-
-
30744471717
-
53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis
-
Morales, J.C., Franco, S., Murphy, M.M., Bassing, C.H., Mills, K.D., Adams, M.M., Walsh, N.C., Manis, J.P., Rassidakis, G.Z., Alt, F.W., Carpenter, P.B., 53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis. Proc. Natl. Acad. Sci. USA 103 (2006), 3310–3315.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 3310-3315
-
-
Morales, J.C.1
Franco, S.2
Murphy, M.M.3
Bassing, C.H.4
Mills, K.D.5
Adams, M.M.6
Walsh, N.C.7
Manis, J.P.8
Rassidakis, G.Z.9
Alt, F.W.10
Carpenter, P.B.11
-
39
-
-
75949122330
-
53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair
-
Noon, A.T., Shibata, A., Rief, N., Löbrich, M., Stewart, G.S., Jeggo, P.A., Goodarzi, A.A., 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair. Nat. Cell Biol. 12 (2010), 177–184.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 177-184
-
-
Noon, A.T.1
Shibata, A.2
Rief, N.3
Löbrich, M.4
Stewart, G.S.5
Jeggo, P.A.6
Goodarzi, A.A.7
-
40
-
-
84883183501
-
Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response
-
Reinhardt, H.C., Yaffe, M.B., Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response. Nat. Rev. Mol. Cell Biol. 14 (2013), 563–580.
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 563-580
-
-
Reinhardt, H.C.1
Yaffe, M.B.2
-
41
-
-
17944379798
-
ASPP proteins specifically stimulate the apoptotic function of p53
-
Samuels-Lev, Y., O'Connor, D.J., Bergamaschi, D., Trigiante, G., Hsieh, J.K., Zhong, S., Campargue, I., Naumovski, L., Crook, T., Lu, X., ASPP proteins specifically stimulate the apoptotic function of p53. Mol. Cell 8 (2001), 781–794.
-
(2001)
Mol. Cell
, vol.8
, pp. 781-794
-
-
Samuels-Lev, Y.1
O'Connor, D.J.2
Bergamaschi, D.3
Trigiante, G.4
Hsieh, J.K.5
Zhong, S.6
Campargue, I.7
Naumovski, L.8
Crook, T.9
Lu, X.10
-
42
-
-
33845270990
-
Regulating the p53 pathway: in vitro hypotheses, in vivo veritas
-
Toledo, F., Wahl, G.M., Regulating the p53 pathway: in vitro hypotheses, in vivo veritas. Nat. Rev. Cancer 6 (2006), 909–923.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 909-923
-
-
Toledo, F.1
Wahl, G.M.2
-
43
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev, L.T., Vu, B.T., Graves, B., Carvajal, D., Podlaski, F., Filipovic, Z., Kong, N., Kammlott, U., Lukacs, C., Klein, C., et al. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 303 (2004), 844–848.
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
-
44
-
-
65349103899
-
Blinded by the Light: The Growing Complexity of p53
-
Vousden, K.H., Prives, C., Blinded by the Light: The Growing Complexity of p53. Cell 137 (2009), 413–431.
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
45
-
-
2542463148
-
53BP1 is required for class switch recombination
-
Ward, I.M., Reina-San-Martin, B., Olaru, A., Minn, K., Tamada, K., Lau, J.S., Cascalho, M., Chen, L., Nussenzweig, A., Livak, F., et al. 53BP1 is required for class switch recombination. J. Cell Biol. 165 (2004), 459–464.
-
(2004)
J. Cell Biol.
, vol.165
, pp. 459-464
-
-
Ward, I.M.1
Reina-San-Martin, B.2
Olaru, A.3
Minn, K.4
Tamada, K.5
Lau, J.S.6
Cascalho, M.7
Chen, L.8
Nussenzweig, A.9
Livak, F.10
-
46
-
-
27644593844
-
53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice
-
Ward, I.M., Difilippantonio, S., Minn, K., Mueller, M.D., Molina, J.R., Yu, X., Frisk, C.S., Ried, T., Nussenzweig, A., Chen, J., 53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice. Mol. Cell. Biol. 25 (2005), 10079–10086.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 10079-10086
-
-
Ward, I.M.1
Difilippantonio, S.2
Minn, K.3
Mueller, M.D.4
Molina, J.R.5
Yu, X.6
Frisk, C.S.7
Ried, T.8
Nussenzweig, A.9
Chen, J.10
-
47
-
-
33846015507
-
The tandem BRCT domain of 53BP1 is not required for its repair function
-
Ward, I., Kim, J.-E., Minn, K., Chini, C.C., Mer, G., Chen, J., The tandem BRCT domain of 53BP1 is not required for its repair function. J. Biol. Chem. 281 (2006), 38472–38477.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 38472-38477
-
-
Ward, I.1
Kim, J.-E.2
Minn, K.3
Chini, C.C.4
Mer, G.5
Chen, J.6
-
48
-
-
59449094470
-
An oligomerized 53BP1 tudor domain suffices for recognition of DNA double-strand breaks
-
Zgheib, O., Pataky, K., Brugger, J., Halazonetis, T.D., An oligomerized 53BP1 tudor domain suffices for recognition of DNA double-strand breaks. Mol. Cell. Biol. 29 (2009), 1050–1058.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 1050-1058
-
-
Zgheib, O.1
Pataky, K.2
Brugger, J.3
Halazonetis, T.D.4
-
49
-
-
33746766974
-
A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response
-
Zhang, D., Zaugg, K., Mak, T.W., Elledge, S.J., A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response. Cell 126 (2006), 529–542.
-
(2006)
Cell
, vol.126
, pp. 529-542
-
-
Zhang, D.1
Zaugg, K.2
Mak, T.W.3
Elledge, S.J.4
-
51
-
-
84873488846
-
53BP1 regulates DSB repair using Rif1 to control 5′ end resection
-
Zimmermann, M., Lottersberger, F., Buonomo, S.B., Sfeir, A., de Lange, T., 53BP1 regulates DSB repair using Rif1 to control 5′ end resection. Science 339 (2013), 700–704.
-
(2013)
Science
, vol.339
, pp. 700-704
-
-
Zimmermann, M.1
Lottersberger, F.2
Buonomo, S.B.3
Sfeir, A.4
de Lange, T.5
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