-
1
-
-
70349859881
-
DNA damage, aging, and cancer
-
Hoeijmakers, J. H. (2009) DNA damage, aging, and cancer. N. Engl. J. Med. 361, 1475-1485
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 1475-1485
-
-
Hoeijmakers, J.H.1
-
2
-
-
78649336706
-
The DNA damage response: Making it safe to play with knives
-
Ciccia, A., and Elledge, S. J. (2010) The DNA damage response: making it safe to play with knives. Mol. Cell 40, 179-204
-
(2010)
Mol. Cell
, vol.40
, pp. 179-204
-
-
Ciccia, A.1
Elledge, S.J.2
-
3
-
-
84906959763
-
CBX8, a novel DNA repair protein, promotes tumorigenesis in human esophageal carcinoma
-
Xiao, W., Ou, C., Qin, J., Xing, F., Sun, Y., Li, Z., and Qiu, J. (2014) CBX8, a novel DNA repair protein, promotes tumorigenesis in human esophageal carcinoma. Int. J. Clin. Exp. Pathol. 7, 4817- 4826
-
(2014)
Int. J. Clin. Exp. Pathol.
, vol.7
, pp. 4817-4826
-
-
Xiao, W.1
Ou, C.2
Qin, J.3
Xing, F.4
Sun, Y.5
Li, Z.6
Qiu, J.7
-
4
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson, S. P., and Bartek, J. (2009) The DNA-damage response in human biology and disease. Nature 461, 1071-1078
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
5
-
-
65149084552
-
Crosstalk between histone modifications during the DNA damage response
-
van Attikum, H., and Gasser, S. M. (2009) Crosstalk between histone modifications during the DNA damage response. Trends Cell Biol. 19, 207-217
-
(2009)
Trends Cell Biol
, vol.19
, pp. 207-217
-
-
Van Attikum, H.1
Gasser, S.M.2
-
6
-
-
80053555789
-
More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance
-
Lukas, J., Lukas, C., and Bartek, J. (2011) More than just a focus: the chromatin response to DNA damage and its role in genome integrity maintenance. Nat Cell Biol. 13, 1161-1169
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1161-1169
-
-
Lukas, J.1
Lukas, C.2
Bartek, J.3
-
7
-
-
43149119233
-
Chromatin-remodelling mechanisms in cancer
-
Lafon-Hughes, L., Di Tomaso, M. V., Méndez-Acuña, L., and Martínez-López, W. (2008) Chromatin-remodelling mechanisms in cancer. Mutat. Res. 658, 191-214
-
(2008)
Mutat. Res.
, vol.658
, pp. 191-214
-
-
Lafon-Hughes, L.1
Di Tomaso, M.V.2
Méndez-Acuña, L.3
Martínez-López, W.4
-
8
-
-
56149091431
-
The role of poly(ADP-ribosyl)ation in epigenetic events
-
Quénet, D., El Ramy, R., Schreiber, V., and Dantzer, F. (2009) The role of poly(ADP-ribosyl)ation in epigenetic events. Int. J.. Biochem. Cell Biol. 41, 60-65
-
(2009)
Int. J.. Biochem. Cell Biol.
, vol.41
, pp. 60-65
-
-
Quénet, D.1
El Ramy, R.2
Schreiber, V.3
Dantzer, F.4
-
9
-
-
66349130703
-
Chromatin dynamics coupled to DNA repair
-
Huertas, D., Sendra, R., and Muñoz, P. (2009) Chromatin dynamics coupled to DNA repair. Epigenetics 4, 31-42
-
(2009)
Epigenetics
, vol.4
, pp. 31-42
-
-
Huertas, D.1
Sendra, R.2
Muñoz, P.3
-
10
-
-
79551562850
-
Chromatin dynamics during repair of chromosomal DNA double-strand breaks
-
Sinha, M., and Peterson, C. L. (2009) Chromatin dynamics during repair of chromosomal DNA double-strand breaks. Epigenomics 1, 371-385
-
(2009)
Epigenomics
, vol.1
, pp. 371-385
-
-
Sinha, M.1
Peterson, C.L.2
-
11
-
-
77953995002
-
Covalent histone modifications: Miswritten, misinterpreted and mis-erased in human cancers
-
Chi, P., Allis, C. D., and Wang, G. G. (2010) Covalent histone modifications: miswritten, misinterpreted and mis-erased in human cancers. Nat. Rev. Cancer 10, 457-469
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 457-469
-
-
Chi, P.1
Allis, C.D.2
Wang, G.G.3
-
12
-
-
79551529513
-
Chromatin dynamics and the repair of DNA double strand breaks
-
Xu, Y., and Price, B. D. (2011) Chromatin dynamics and the repair of DNA double strand breaks. Cell Cycle 10, 261-267
-
(2011)
Cell Cycle
, vol.10
, pp. 261-267
-
-
Xu, Y.1
Price, B.D.2
-
13
-
-
0033198919
-
Poly-(ADP-ribosyl)ation reactions in the regulation of nuclear functions
-
D'Amours, D., Desnoyers, S., D'Silva, I., and Poirier, G. G. (1999) Poly-(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem. J. 342, 249-268
-
(1999)
Biochem. J.
, vol.342
, pp. 249-268
-
-
D'Amours, D.1
Desnoyers, S.2
D'Silva, I.3
Poirier, G.G.4
-
14
-
-
84989874546
-
Role of biomarkers in the development of PARP inhibitors
-
Ganguly, B., Dolfi, S. C., Rodriguez-Rodriguez, L., Ganesan, S., and Hirshfield, K. M. (2016) Role of biomarkers in the development of PARP inhibitors. Biomark Cancer 8, 15-25
-
(2016)
Biomark Cancer
, vol.8
, pp. 15-25
-
-
Ganguly, B.1
Dolfi, S.C.2
Rodriguez-Rodriguez, L.3
Ganesan, S.4
Hirshfield, K.M.5
-
15
-
-
79954560252
-
Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations
-
Dedes, K. J., Wilkerson, P. M., Wetterskog, D., Weigelt, B., Ashworth, A., and Reis-Filho, J. S. (2011) Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations. Cell Cycle 10, 1192-1199
-
(2011)
Cell Cycle
, vol.10
, pp. 1192-1199
-
-
Dedes, K.J.1
Wilkerson, P.M.2
Wetterskog, D.3
Weigelt, B.4
Ashworth, A.5
Reis-Filho, J.S.6
-
16
-
-
38049064044
-
Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins
-
Ahel, I., Ahel, D., Matsusaka, T., Clark, A. J., Pines, J., Boulton, S. J., and West, S. C. (2008) Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins. Nature 451, 81-85
-
(2008)
Nature
, vol.451
, pp. 81-85
-
-
Ahel, I.1
Ahel, D.2
Matsusaka, T.3
Clark, A.J.4
Pines, J.5
Boulton, S.J.6
West, S.C.7
-
17
-
-
58749112769
-
Proteome-wide identification of poly(ADPribose) binding proteins and poly(ADP-ribose)-associated protein complexes
-
Gagné, J. P., Isabelle, M., Lo, K. S., Bourassa, S., Hendzel, M. J., Dawson, V. L., Dawson, T. M., and Poirier, G. G. (2008) Proteome-wide identification of poly(ADPribose) binding proteins and poly(ADP-ribose)-associated protein complexes. Nucleic Acids Res. 36, 6959- 6976
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 6959-6976
-
-
Gagné, J.P.1
Isabelle, M.2
Lo, K.S.3
Bourassa, S.4
Hendzel, M.J.5
Dawson, L.6
Dawson, T.M.7
Poirier, G.G.8
-
18
-
-
69949123856
-
Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1
-
Ahel, D., Horejsí, Z., Wiechens, N., Polo, S. E., Garcia-Wilson, E., Ahel, I., Flynn, H., Skehel, M., West, S. C., Jackson, S. P., Owen-Hughes, T., and Boulton, S. J. (2009) Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. Science 325, 1240-1243
-
(2009)
Science
, vol.325
, pp. 1240-1243
-
-
Ahel, D.1
Horejsí, Z.2
Wiechens, N.3
Polo, S.E.4
Garcia-Wilson, E.5
Ahel, I.6
Flynn, H.7
Skehel, M.8
West, S.C.9
Jackson, S.P.10
Owen-Hughes, T.11
Boulton, S.J.12
-
19
-
-
79956086415
-
BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair
-
Ginjala, V., Nacerddine, K., Kulkarni, A., Oza, J., Hill, S. J., Yao, M., Citterio, E., van Lohuizen, M., and Ganesan, S. (2011) BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair. Mol. Cell. Biol. 31, 1972-1982
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 1972-1982
-
-
Ginjala, V.1
Nacerddine, K.2
Kulkarni, A.3
Oza, J.4
Hill, S.J.5
Yao, M.6
Citterio, E.7
Van Lohuizen, M.8
Ganesan, S.9
-
20
-
-
0033552813
-
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
-
Jacobs, J. J., Kieboom, K., Marino, S., DePinho, R. A., and van Lohuizen, M. (1999) The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 397, 164-168
-
(1999)
Nature
, vol.397
, pp. 164-168
-
-
Jacobs, J.J.1
Kieboom, K.2
Marino, S.3
DePinho, R.A.4
Van Lohuizen, M.5
-
21
-
-
43249118972
-
Polycomb group genes: Keeping stem cell activity in balance
-
Sauvageau, M., and Sauvageau, G. (2008) Polycomb group genes: keeping stem cell activity in balance. PLoS Biol. 6, e113
-
(2008)
PLoS Biol
, vol.6
, pp. e113
-
-
Sauvageau, M.1
Sauvageau, G.2
-
22
-
-
44649200464
-
Polycomb complexes and epigenetic states
-
Schwartz, Y. B., and Pirrotta, V. (2008) Polycomb complexes and epigenetic states. Curr. Opin. Cell Biol. 20, 266-273
-
(2008)
Curr. Opin. Cell Biol.
, vol.20
, pp. 266-273
-
-
Schwartz, Y.B.1
Pirrotta, V.2
-
23
-
-
62049085937
-
Critical role of the Polycomb and Trithorax complexes in the maintenance of CD4 T cell memory
-
Nakayama, T., and Yamashita, M. (2009) Critical role of the Polycomb and Trithorax complexes in the maintenance of CD4 T cell memory. Semin. Immunol. 21, 78-83
-
(2009)
Semin. Immunol.
, vol.21
, pp. 78-83
-
-
Nakayama, T.1
Yamashita, M.2
-
24
-
-
84855493840
-
Cbx proteins help ESCs walk the line between self-renewal and differentiation
-
Camahort, R., and Cowan, C. A. (2012) Cbx proteins help ESCs walk the line between self-renewal and differentiation. Cell Stem Cell 10, 4-6
-
(2012)
Cell Stem Cell
, vol.10
, pp. 4-6
-
-
Camahort, R.1
Cowan, C.A.2
-
25
-
-
84855516244
-
Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells
-
Morey, L., Pascual, G., Cozzuto, L., Roma, G., Wutz, A., Benitah, S. A., and Di Croce, L. (2012) Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells. Cell Stem Cell 10, 47-62
-
(2012)
Cell Stem Cell
, vol.10
, pp. 47-62
-
-
Morey, L.1
Pascual, G.2
Cozzuto, L.3
Roma, G.4
Wutz, A.5
Benitah, S.A.6
Di Croce, L.7
-
26
-
-
84862908896
-
MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation
-
O'Loghlen, A., Muñoz-Cabello, A. M., Gaspar-Maia, A., Wu, H. A., Banito, A., Kunowska, N., Racek, T., Pemberton, H. N., Beolchi, P., Lavial, F., Masui, O., Vermeulen, M., Carroll, T., Graumann, J., Heard, E., et al. (2012) MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation. Cell Stem Cell 10, 33-46
-
(2012)
Cell Stem Cell
, vol.10
, pp. 33-46
-
-
O'Loghlen, A.1
Muñoz-Cabello, A.M.2
Gaspar-Maia, A.3
Wu, H.A.4
Banito, A.5
Kunowska, N.6
Racek, T.7
Pemberton, H.N.8
Beolchi, P.9
Lavial, F.10
Masui, O.11
Vermeulen, M.12
Carroll, T.13
Graumann, J.14
Heard, E.15
-
27
-
-
34247164462
-
Involvement of homologous recombination in carcinogenesis
-
Reliene, R., Bishop, A. J., and Schiestl, R. H. (2007) Involvement of homologous recombination in carcinogenesis. Adv. Genet. 58, 67-87
-
(2007)
Adv. Genet
, vol.58
, pp. 67-87
-
-
Reliene, R.1
Bishop, A.J.2
Schiestl, R.H.3
-
28
-
-
8844265508
-
Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins
-
Ringrose, L., and Paro, R. (2004) Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu. Rev. Genet. 38, 413-443
-
(2004)
Annu. Rev. Genet.
, vol.38
, pp. 413-443
-
-
Ringrose, L.1
Paro, R.2
-
29
-
-
7244234099
-
Role of histone H2A ubiquitination in Polycomb silencing
-
Wang, H., Wang, L., Erdjument-Bromage, H., Vidal, M., Tempst, P., Jones, R. S., and Zhang, Y. (2004) Role of histone H2A ubiquitination in Polycomb silencing. Nature 431, 873-7878
-
(2004)
Nature
, vol.431
, pp. 873-7878
-
-
Wang, H.1
Wang, L.2
Erdjument-Bromage, H.3
Vidal, M.4
Tempst, P.5
Jones, R.S.6
Zhang, Y.7
-
30
-
-
33847084602
-
Genome regulation by polycomb and trithorax proteins
-
Schuettengruber, B., Chourrout, D., Vervoort, M., Leblanc, B., and Cavalli, G. (2007) Genome regulation by polycomb and trithorax proteins. Cell 128, 735-745
-
(2007)
Cell
, vol.128
, pp. 735-745
-
-
Schuettengruber, B.1
Chourrout, D.2
Vervoort, M.3
Leblanc, B.4
Cavalli, G.5
-
31
-
-
42749083114
-
Programming of gene expression by Polycomb group proteins
-
Köhler, C., and Villar, C. B. (2008) Programming of gene expression by Polycomb group proteins. Trends Cell Biol. 18, 236-243
-
(2008)
Trends Cell Biol
, vol.18
, pp. 236-243
-
-
Köhler, C.1
Villar, C.B.2
-
32
-
-
0026098009
-
The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila
-
Paro, R., and Hogness, D. S. (1991) The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila. Proc. Natl. Acad. Sci. U.S.A. 88, 263-267
-
(1991)
Proc. Natl. Acad. Sci. U.S.A.
, vol.88
, pp. 263-267
-
-
Paro, R.1
Hogness, D.S.2
-
33
-
-
78649349810
-
A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
-
Chou, D. M., Adamson, B., Dephoure, N. E., Tan, X., Nottke, A. C., Hurov, K. E., Gygi, S. P., Colaiácovo, M. P., and Elledge, S. J. (2010) A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage. Proc. Natl. Acad. Sci. U.S.A. 107, 18475-18480
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 18475-18480
-
-
Chou, D.M.1
Adamson, B.2
Dephoure, N.E.3
Tan, X.4
Nottke, A.C.5
Hurov, K.E.6
Gygi, S.P.7
Colaiácovo, M.P.8
Elledge, S.J.9
-
34
-
-
0029071015
-
Mechanisms of radiosensitization in iododeoxyuridine-substituted cells. Int
-
Jones, G. D., Ward, J. F., Limoli, C. L., Moyer, D. J., and Aguilera, J. A. (1995) Mechanisms of radiosensitization in iododeoxyuridine-substituted cells. Int. J. Radiat. Biol. 67, 647-653
-
(1995)
J. Radiat. Biol.
, vol.67
, pp. 647-653
-
-
Jones, G.D.1
Ward, J.F.2
Limoli, C.L.3
Moyer, D.J.4
Aguilera, J.A.5
-
35
-
-
74049150799
-
Novel motifs distinguish multiple homologues of Polycomb in vertebrates: Expansion and diversification of the epigenetic toolkit
-
Senthilkumar, R., and Mishra, R. K. (2009) Novel motifs distinguish multiple homologues of Polycomb in vertebrates: expansion and diversification of the epigenetic toolkit. BMC Genomics 10, 549
-
(2009)
BMC Genomics
, vol.10
, pp. 549
-
-
Senthilkumar, R.1
Mishra, R.K.2
-
36
-
-
0035963288
-
The polycomb protein MPc3 interacts with AF9, an MLL fusion partner in t(9; 11)(p22;q23) acute leukemias
-
Hemenway, C. S., de Erkenez, A. C., and Gould, G. C. (2001) The polycomb protein MPc3 interacts with AF9, an MLL fusion partner in t(9; 11)(p22;q23) acute leukemias. Oncogene 20, 3798-3805
-
(2001)
Oncogene
, vol.20
, pp. 3798-3805
-
-
Hemenway, C.S.1
De Erkenez, A.C.2
Gould, G.C.3
-
37
-
-
67649371461
-
DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation
-
Miranda, T. B., Cortez, C. C., Yoo, C. B., Liang, G., Abe, M., Kelly, T. K., Marquez, V. E., and Jones, P. A. (2009) DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation. Mol. Cancer Ther. 8, 1579-1588
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 1579-1588
-
-
Miranda, T.B.1
Cortez, C.C.2
Yoo, C.B.3
Liang, G.4
Abe, M.5
Kelly, T.K.6
Marquez, V.E.7
Jones, P.A.8
-
38
-
-
84870573126
-
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
-
McCabe, M. T., Ott, H. M., Ganji, G., Korenchuk, S., Thompson, C., Van Aller, G. S., Liu, Y., Graves, A. P., Della Pietra, A., 3rd, Diaz, E., LaFrance, L. V., Mellinger, M., Duquenne, C., Tian, X., Kruger, R. G., et al. (2012) EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations. Nature 492, 108-112
-
(2012)
Nature
, vol.492
, pp. 108-112
-
-
McCabe, M.T.1
Ott, H.M.2
Ganji, G.3
Korenchuk, S.4
Thompson, C.5
Van Aller, G.S.6
Liu, Y.7
Graves, A.P.8
Della Pietra, A.9
Diaz, E.10
LaFrance L, V.11
Mellinger, M.12
Duquenne, C.13
Tian, X.14
Kruger, R.G.15
-
39
-
-
0034666145
-
HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties
-
Bárdos, J. I., Saurin, A. J., Tissot, C., Duprez, E., and Freemont, P. S. (2000) HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties. J. Biol. Chem. 275, 28785-28792
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28785-28792
-
-
Bárdos, J.I.1
Saurin, A.J.2
Tissot, C.3
Duprez, E.4
Freemont, P.S.5
-
40
-
-
84879636711
-
Strategies for optimizing the response of cancer and normal tissues to radiation
-
Moding, E. J., Kastan, M. B., and Kirsch, D. G. (2013) Strategies for optimizing the response of cancer and normal tissues to radiation. Nat. Rev. Drug Discovery 12, 526-542
-
(2013)
Nat. Rev. Drug Discovery
, vol.12
, pp. 526-542
-
-
Moding, E.J.1
Kastan, M.B.2
Kirsch, D.G.3
-
41
-
-
84941809696
-
The replication checkpoint prevents two types of fork collapse without regulating replisome stability
-
Dungrawala, H., Rose, K. L., Bhat, K. P., Mohni, K. N., Glick, G. G., Couch, F. B., and Cortez, D. (2015) The replication checkpoint prevents two types of fork collapse without regulating replisome stability. Mol. Cell 59, 998-1010
-
(2015)
Mol. Cell
, vol.59
, pp. 998-1010
-
-
Dungrawala, H.1
Rose, K.L.2
Bhat, K.P.3
Mohni, K.N.4
Glick, G.G.5
Couch, F.B.6
Cortez, D.7
-
42
-
-
38049007502
-
Feedback-regulated poly(ADPribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells
-
Mortusewicz, O., Amé, J. C., Schreiber, V., and Leonhardt, H. (2007) Feedback-regulated poly(ADPribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells. Nucleic Acids Res. 35, 7665-7675
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7665-7675
-
-
Mortusewicz, O.1
Amé, J.C.2
Schreiber, V.3
Leonhardt, H.4
-
43
-
-
38149057387
-
PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites
-
Haince, J. F., McDonald, D., Rodrigue, A., Déry, U., Masson, J. Y., Hendzel, M. J., and Poirier, G. G. (2008) PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites. J. Biol. Chem. 283, 1197-1208
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 1197-1208
-
-
Haince, J.F.1
McDonald, D.2
Rodrigue, A.3
Déry, U.4
Masson, J.Y.5
Hendzel, M.J.6
Poirier, G.G.7
-
44
-
-
21244444665
-
The macro domain is an ADP-ribose, binding module
-
Karras, G. I., Kustatscher, G., Buhecha, H. R., Allen, M. D., Pugieux, C., Sait, F., Bycroft, M., and Ladurner, A. G. (2005) The macro domain is an ADP-ribose, binding module. EMBO J. 24, 1911-1920
-
(2005)
EMBO J
, vol.24
, pp. 1911-1920
-
-
Karras, G.I.1
Kustatscher, G.2
Buhecha, H.R.3
Allen, M.D.4
Pugieux, C.5
Sait, F.6
Bycroft, M.7
Ladurner, A.G.8
-
45
-
-
76349105464
-
Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADPribose)
-
Eustermann, S., Brockmann, C., Mehrotra, P. V., Yang, J. C., Loakes, D., West, S. C., Ahel, I., and Neuhaus, D. (2010) Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADPribose). Nat. Struct. Mol. Biol. 17, 241-243
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 241-243
-
-
Eustermann, S.1
Brockmann, C.2
Mehrotra, P.V.3
Yang, J.C.4
Loakes, D.5
West, S.C.6
Ahel, I.7
Neuhaus, D.8
-
46
-
-
3142600897
-
Molecular cloning, genomic structure, and expression analysis of the mouse transcriptional intermediary factor 1ô gene
-
Yan, K. P., Dollé, P., Mark, M., Lerouge, T., Wendling, O., Chambon, P., and Losson, R. (2004) Molecular cloning, genomic structure, and expression analysis of the mouse transcriptional intermediary factor 1ô gene. Gene 334, 3-13
-
(2004)
Gene
, vol.334
, pp. 3-13
-
-
Yan, K.P.1
Dollé, P.2
Mark, M.3
Lerouge, T.4
Wendling, O.5
Chambon, P.6
Losson, R.7
-
47
-
-
84887503435
-
Tripartite Motif-containing 33 (TRIM33) Protein Functions in the Poly(ADP-ribose) Polymerase (PARP)-dependent DNA Damage Response through Interaction with Amplified in Liver Cancer 1 (ALC1) Protein
-
Kulkarni, A., Oza, J., Yao, M., Sohail, H., Ginjala, V., Tomas-Loba, A., Horejsi, Z., Tan, A. R., Boulton, S. J., and Ganesan, S. (2013) Tripartite Motif-containing 33 (TRIM33) Protein Functions in the Poly(ADP-ribose) Polymerase (PARP)-dependent DNA Damage Response through Interaction with Amplified in Liver Cancer 1 (ALC1) Protein. J. Biol. Chem. 288, 32357-32369
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 32357-32369
-
-
Kulkarni, A.1
Oza, J.2
Yao, M.3
Sohail, H.4
Ginjala, V.5
Tomas-Loba, A.6
Horejsi, Z.7
Tan, A.R.8
Boulton, S.J.9
Ganesan, S.10
-
48
-
-
0029899891
-
Genetic manipulation of genomes with rare-cutting endonucleases
-
Jasin, M. (1996) Genetic manipulation of genomes with rare-cutting endonucleases. Trends Genet. 12, 224-228
-
(1996)
Trends Genet
, vol.12
, pp. 224-228
-
-
Jasin, M.1
-
49
-
-
33745200945
-
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2
-
Xia, B., Sheng, Q., Nakanishi, K., Ohashi, A., Wu, J., Christ, N., Liu, X., Jasin, M., Couch, F. J., and Livingston, D. M. (2006) Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. Mol. Cell 22, 719-729
-
(2006)
Mol. Cell
, vol.22
, pp. 719-729
-
-
Xia, B.1
Sheng, Q.2
Nakanishi, K.3
Ohashi, A.4
Wu, J.5
Christ, N.6
Liu, X.7
Jasin, M.8
Couch, F.J.9
Livingston, D.M.10
-
50
-
-
46249131123
-
Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair
-
Bennardo, N., Cheng, A., Huang, N., and Stark, J. M. (2008) Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet. 4, e1000110
-
(2008)
PLoS Genet
, vol.4
, pp. e1000110
-
-
Bennardo, N.1
Cheng, A.2
Huang, N.3
Stark, J.M.4
-
51
-
-
84919485360
-
Chromatin modifications and DNA repair: Beyond double-strand breaks
-
House, N. C., Koch, M. R., and Freudenreich, C. H. (2014) Chromatin modifications and DNA repair: beyond double-strand breaks. Front. Genet. 5, 296
-
(2014)
Front. Genet.
, vol.5
, pp. 296
-
-
House, N.C.1
Koch, M.R.2
Freudenreich, C.H.3
-
52
-
-
77955381770
-
BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery
-
Facchino, S., Abdouh, M., Chatoo, W., and Bernier, G. (2010) BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery. J. Neurosci. 30, 10096-10111
-
(2010)
J. Neurosci.
, vol.30
, pp. 10096-10111
-
-
Facchino, S.1
Abdouh, M.2
Chatoo, W.3
Bernier, G.4
-
53
-
-
77957748289
-
BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair
-
Ismail, I. H., Andrin, C., McDonald, D., and Hendzel, M. J. (2010) BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair. J. Cell Biol. 191, 45-60
-
(2010)
J. Cell Biol.
, vol.191
, pp. 45-60
-
-
Ismail, I.H.1
Andrin, C.2
McDonald, D.3
Hendzel, M.J.4
-
54
-
-
33645231102
-
Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin
-
Bernstein, E., Duncan, E. M., Masui, O., Gil, J., Heard, E., and Allis, C. D. (2006) Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin. Mol. Cell. Biol. 26, 2560-2569
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 2560-2569
-
-
Bernstein, E.1
Duncan, E.M.2
Masui, O.3
Gil, J.4
Heard, E.5
Allis, C.D.6
-
55
-
-
78650964531
-
Recognition and specificity determinants of the human Cbx chromodomains
-
Kaustov, L., Ouyang, H., Amaya, M., Lemak, A., Nady, N., Duan, S., Wasney, G. A., Li, Z., Vedadi, M., Schapira, M., Min, J., and Arrowsmith, C. H. (2011) Recognition and specificity determinants of the human Cbx chromodomains. J. Biol. Chem. 286, 521-529
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 521-529
-
-
Kaustov, L.1
Ouyang, H.2
Amaya, M.3
Lemak, A.4
Nady, N.5
Duan, S.6
Wasney, G.A.7
Li, Z.8
Vedadi, M.9
Schapira, M.10
Min, J.11
Arrowsmith, C.H.12
-
56
-
-
84863011309
-
PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes
-
Gao, Z., Zhang, J., Bonasio, R., Strino, F., Sawai, A., Parisi, F., Kluger, Y., and Reinberg, D. (2012) PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes. Mol. Cell 45, 344-356
-
(2012)
Mol. Cell
, vol.45
, pp. 344-356
-
-
Gao, Z.1
Zhang, J.2
Bonasio, R.3
Strino, F.4
Sawai, A.5
Parisi, F.6
Kluger, Y.7
Reinberg, D.8
-
57
-
-
84857367297
-
RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3
-
Tavares, L., Dimitrova, E., Oxley, D., Webster, J., Poot, R., Demmers, J., Bezstarosti, K., Taylor, S., Ura, H., Koide, H., Wutz, A., Vidal, M., Elderkin, S., and Brockdorff, N. (2012) RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3. Cell 148, 664- 678
-
(2012)
Cell
, vol.148
, pp. 664-678
-
-
Tavares, L.1
Dimitrova, E.2
Oxley, D.3
Webster, J.4
Poot, R.5
Demmers, J.6
Bezstarosti, K.7
Taylor, S.8
Ura, H.9
Koide, H.10
Wutz, A.11
Vidal, M.12
Elderkin, S.13
Brockdorff, N.14
-
58
-
-
77953720192
-
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks
-
Shanbhag, N. M., Rafalska-Metcalf, I. U., Balane-Bolivar, C., Janicki, S. M., and Greenberg, R. A. (2010) ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks. Cell 141, 970-981
-
(2010)
Cell
, vol.141
, pp. 970-981
-
-
Shanbhag, N.M.1
Rafalska-Metcalf, I.U.2
Balane-Bolivar, C.3
Janicki, S.M.4
Greenberg, R.A.5
-
59
-
-
55949121452
-
Different polycomb group CBX family proteinsassociate with distinct regions of chromatin using nonhomologous protein sequences
-
Vincenz, C., and Kerppola, T. K. (2008) Different polycomb group CBX familyproteinsassociatewithdistinctregionsofchromatinusingnonhomologous protein sequences. Proc. Natl. Acad. Sci. U.S.A. 105, 16572-16577
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 16572-16577
-
-
Vincenz, C.1
Kerppola, T.K.2
-
60
-
-
4444349390
-
Analyzing cell cycle checkpoints after ionizing Radiation
-
Xu, B., and Kastan, M. B. (2004) Analyzing cell cycle checkpoints after ionizing Radiation. Methods Mol Biol. 281, 283-292
-
(2004)
Methods Mol Biol
, vol.281
, pp. 283-292
-
-
Xu, B.1
Kastan, M.B.2
-
61
-
-
34548313955
-
Clonogenic assay of cells in vitro
-
Franken, N. A., Rodermond, H. M., Stap, J., Haveman, J., and van Bree, C. (2006) Clonogenic assay of cells in vitro. Nat. Protoc. 1, 2315-2319
-
(2006)
Nat. Protoc.
, vol.1
, pp. 2315-2319
-
-
Franken, N.A.1
Rodermond, H.M.2
Stap, J.3
Haveman, J.4
Van Bree, C.5
-
62
-
-
0347381286
-
Immunoaffinity purification of mammalian protein complexes
-
Nakatani, Y., and Ogryzko, V. (2003) Immunoaffinity purification of mammalian protein complexes. Methods Enzymol. 370, 430-444
-
(2003)
Methods Enzymol
, vol.370
, pp. 430-444
-
-
Nakatani, Y.1
Ogryzko, V.2
|