메뉴 건너뛰기




Volumn 6, Issue 4, 2008, Pages 678-681

Polycomb group genes: Keeping stem cell activity in balance

Author keywords

[No Author keywords available]

Indexed keywords

POLYCOMB GROUP PROTEIN; REPRESSOR PROTEIN;

EID: 43249118972     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0060113     Document Type: Review
Times cited : (44)

References (31)
  • 1
    • 0037111831 scopus 로고    scopus 로고
    • Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
    • Kuzmichev A, Nishioka K, Erdjument-Bromage H, Tempst P, Reinberg D (2002) Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev 16: 2893-2905.
    • (2002) Genes Dev , vol.16 , pp. 2893-2905
    • Kuzmichev, A.1    Nishioka, K.2    Erdjument-Bromage, H.3    Tempst, P.4    Reinberg, D.5
  • 3
    • 0036340237 scopus 로고    scopus 로고
    • The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans
    • Levine SS, Weiss A, Erdjument-Bromage H, Shao Z, Tempst P, et al. (2002) The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans. Mol Cell Biol 22: 6070-6078.
    • (2002) Mol Cell Biol , vol.22 , pp. 6070-6078
    • Levine, S.S.1    Weiss, A.2    Erdjument-Bromage, H.3    Shao, Z.4    Tempst, P.5
  • 4
    • 8144230178 scopus 로고    scopus 로고
    • Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
    • Pasini D, Bracken AP, Jensen MR, Lazzerini Denchi E, Helin K (2004) Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity. Embo J 23: 4061-4071.
    • (2004) Embo J , vol.23 , pp. 4061-4071
    • Pasini, D.1    Bracken, A.P.2    Jensen, M.R.3    Lazzerini Denchi, E.4    Helin, K.5
  • 5
    • 20144363347 scopus 로고    scopus 로고
    • The murine polycomb group protein Eed is required for global histone H3 lysine-27 methylation
    • Montgomery ND, Yee D, Chen A, Kalantry S, Chamberlain SJ, et al. (2005) The murine polycomb group protein Eed is required for global histone H3 lysine-27 methylation. Curr Biol 15: 942-947.
    • (2005) Curr Biol , vol.15 , pp. 942-947
    • Montgomery, N.D.1    Yee, D.2    Chen, A.3    Kalantry, S.4    Chamberlain, S.J.5
  • 6
    • 33646870495 scopus 로고    scopus 로고
    • Genomewide mapping of Polycomb target genes unravels their roles in cell fate transitions
    • Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K (2006) Genomewide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 20: 1123-1136.
    • (2006) Genes Dev , vol.20 , pp. 1123-1136
    • Bracken, A.P.1    Dietrich, N.2    Pasini, D.3    Hansen, K.H.4    Helin, K.5
  • 7
    • 17644410781 scopus 로고    scopus 로고
    • Nucleosome binding and histone methyltransferase activity of Drosophila PRC2
    • Nekrasov M, Wild B, Muller J (2005) Nucleosome binding and histone methyltransferase activity of Drosophila PRC2. EMBO Rep 6: 348-353.
    • (2005) EMBO Rep , vol.6 , pp. 348-353
    • Nekrasov, M.1    Wild, B.2    Muller, J.3
  • 8
    • 0036830642 scopus 로고    scopus 로고
    • Role of histone H3 lysine 27 methylation in Polycomb-group silencing
    • Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, et al. (2002) Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 298: 1039-1043.
    • (2002) Science , vol.298 , pp. 1039-1043
    • Cao, R.1    Wang, L.2    Wang, H.3    Xia, L.4    Erdjument-Bromage, H.5
  • 9
    • 7244234099 scopus 로고    scopus 로고
    • Role of histone H2A ubiquitination in Polycomb silencing
    • Wang H, Wang L, Erdjument-Bromage H, Vidal M, Tempst P, et al. (2004) Role of histone H2A ubiquitination in Polycomb silencing. Nature 431: 873-878.
    • (2004) Nature , vol.431 , pp. 873-878
    • Wang, H.1    Wang, L.2    Erdjument-Bromage, H.3    Vidal, M.4    Tempst, P.5
  • 10
    • 33750379420 scopus 로고    scopus 로고
    • Polycomb silencers control cell fate, development and cancer
    • Sparmann A, van Lohuizen M (2006) Polycomb silencers control cell fate, development and cancer. Nat Rev Cancer 6: 846-856.
    • (2006) Nat Rev Cancer , vol.6 , pp. 846-856
    • Sparmann, A.1    van Lohuizen, M.2
  • 11
    • 36749089980 scopus 로고    scopus 로고
    • Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells
    • Stock JK, Giadrossi S, Casanova M, Brookes E, Vidal M, et al. (2007) Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells. Nat Cell Biol 9: 1428-1435.
    • (2007) Nat Cell Biol , vol.9 , pp. 1428-1435
    • Stock, J.K.1    Giadrossi, S.2    Casanova, M.3    Brookes, E.4    Vidal, M.5
  • 12
    • 14244266720 scopus 로고    scopus 로고
    • Histone H2A ubiquitination does not preclude histone H1 binding, but it facilitates its association with the nucleosome
    • Jason LJ, Finn RM, Lindsey G, Ausio J (2005) Histone H2A ubiquitination does not preclude histone H1 binding, but it facilitates its association with the nucleosome. J Biol Chem 280: 4975-4982.
    • (2005) J Biol Chem , vol.280 , pp. 4975-4982
    • Jason, L.J.1    Finn, R.M.2    Lindsey, G.3    Ausio, J.4
  • 13
    • 34547730282 scopus 로고    scopus 로고
    • A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation
    • Zhu P, Zhou W, Wang J, Puc J, Ohgi KA, et al. (2007) A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation. Mol Cell 27: 609-621.
    • (2007) Mol Cell , vol.27 , pp. 609-621
    • Zhu, P.1    Zhou, W.2    Wang, J.3    Puc, J.4    Ohgi, K.A.5
  • 14
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, et al. (2006) Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125: 301-313.
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3    Guenther, M.G.4    Levine, S.S.5
  • 15
    • 33646882068 scopus 로고    scopus 로고
    • Polycomb complexes repress developmental regulators in murine embryonic stem cells
    • Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, et al. (2006) Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441: 349-353.
    • (2006) Nature , vol.441 , pp. 349-353
    • Boyer, L.A.1    Plath, K.2    Zeitlinger, J.3    Brambrink, T.4    Medeiros, L.A.5
  • 16
    • 35348850693 scopus 로고    scopus 로고
    • Concise review: Roles of polycomb group proteins in development and disease: A stem cell perspective
    • Rajasekhar VK, Begemann M (2007) Concise review: Roles of polycomb group proteins in development and disease: A stem cell perspective. Stem Cells 25: 2498-2510.
    • (2007) Stem Cells , vol.25 , pp. 2498-2510
    • Rajasekhar, V.K.1    Begemann, M.2
  • 17
    • 0027487387 scopus 로고
    • bmi-1 transgene induces lymphomas and collaborates with myc in tumorigenesis
    • Haupt Y, Bath ML, Harris AW, Adams JM (1993) bmi-1 transgene induces lymphomas and collaborates with myc in tumorigenesis. Oncogene 8: 3161-3164.
    • (1993) Oncogene , vol.8 , pp. 3161-3164
    • Haupt, Y.1    Bath, M.L.2    Harris, A.W.3    Adams, J.M.4
  • 18
    • 0033552813 scopus 로고    scopus 로고
    • The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
    • Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M (1999) The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 397: 164-168.
    • (1999) Nature , vol.397 , pp. 164-168
    • Jacobs, J.J.1    Kieboom, K.2    Marino, S.3    DePinho, R.A.4    van Lohuizen, M.5
  • 19
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J, Sauvageau G (2003) Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423: 255-260.
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 20
    • 0037128662 scopus 로고    scopus 로고
    • Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells
    • Ohta H, Sawada A, Kim JY, Tokimasa S, Nishiguchi S, et al. (2002) Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells. J Exp Med 195: 759-770.
    • (2002) J Exp Med , vol.195 , pp. 759-770
    • Ohta, H.1    Sawada, A.2    Kim, J.Y.3    Tokimasa, S.4    Nishiguchi, S.5
  • 21
    • 18644382388 scopus 로고    scopus 로고
    • The polycomb group protein EZH2 is involved in progression of prostate cancer
    • Varambally S, Dhanasekaran SM, Zhou M, Barrette TR, Kumar-Sinha C, et al. (2002) The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature 419: 624-629.
    • (2002) Nature , vol.419 , pp. 624-629
    • Varambally, S.1    Dhanasekaran, S.M.2    Zhou, M.3    Barrette, T.R.4    Kumar-Sinha, C.5
  • 22
    • 0141816752 scopus 로고    scopus 로고
    • EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
    • Kleer CG, Cao Q, Varambally S, Shen R, Ota I, et al. (2003) EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proc Natl Acad Sci U S A 100: 11606-11611.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 11606-11611
    • Kleer, C.G.1    Cao, Q.2    Varambally, S.3    Shen, R.4    Ota, I.5
  • 23
    • 33344469959 scopus 로고    scopus 로고
    • The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion
    • Kamminga LM, Bystrykh LV, de Boer A, Houwer S, Douma J, et al. (2006) The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. Blood 107: 2170-2179.
    • (2006) Blood , vol.107 , pp. 2170-2179
    • Kamminga, L.M.1    Bystrykh, L.V.2    de Boer, A.3    Houwer, S.4    Douma, J.5
  • 24
    • 0033569427 scopus 로고    scopus 로고
    • Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation
    • Lessard J, Schumacher A, Thorsteinsdottir U, van Lohuizen M, Magnuson T, et al. (1999) Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation. Genes Dev 13: 2691-2703.
    • (1999) Genes Dev , vol.13 , pp. 2691-2703
    • Lessard, J.1    Schumacher, A.2    Thorsteinsdottir, U.3    van Lohuizen, M.4    Magnuson, T.5
  • 25
    • 38349107912 scopus 로고    scopus 로고
    • Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia
    • Sauvageau M, Miller M, Lemieux S, Lessard J, Hebert J, et al. (2008) Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia. Blood 111: 790-799.
    • (2008) Blood , vol.111 , pp. 790-799
    • Sauvageau, M.1    Miller, M.2    Lemieux, S.3    Lessard, J.4    Hebert, J.5
  • 26
    • 0037050254 scopus 로고    scopus 로고
    • The Polycomb-group gene eed regulates thymocyte differentiation and suppresses the development of carcinogen-induced T-cell lymphomas
    • Richie ER, Schumacher A, Angel JM, Holloway M, Rinchik EM, et al. (2002) The Polycomb-group gene eed regulates thymocyte differentiation and suppresses the development of carcinogen-induced T-cell lymphomas. Oncogene 21: 299-306.
    • (2002) Oncogene , vol.21 , pp. 299-306
    • Richie, E.R.1    Schumacher, A.2    Angel, J.M.3    Holloway, M.4    Rinchik, E.M.5
  • 27
    • 43249127096 scopus 로고    scopus 로고
    • Polycomb Repressive Complex 2 (PRC2) restricts hematopoietic stem cell activity
    • doi:10.1371/journal.pbio.0060093
    • Majewski IJ, Blewitt ME, de Graaf CA, McManus EJ, Bahlo M (2008) Polycomb Repressive Complex 2 (PRC2) restricts hematopoietic stem cell activity. PLoS Biol 6(4): e93. doi:10.1371/journal.pbio.0060093
    • (2008) PLoS Biol , vol.6 , Issue.4
    • Majewski, I.J.1    Blewitt, M.E.2    de Graaf, C.A.3    McManus, E.J.4    Bahlo, M.5
  • 28
    • 0035172279 scopus 로고    scopus 로고
    • Lack of the Polycomb-group gene rae28 causes maturation arrest at the early B-cell developmental stage
    • Tokimasa S, Ohta H, Sawada A, Matsuda Y, Kim JY, et al. (2001) Lack of the Polycomb-group gene rae28 causes maturation arrest at the early B-cell developmental stage. Exp Hematol 29: 93-103.
    • (2001) Exp Hematol , vol.29 , pp. 93-103
    • Tokimasa, S.1    Ohta, H.2    Sawada, A.3    Matsuda, Y.4    Kim, J.Y.5
  • 29
    • 0034992693 scopus 로고    scopus 로고
    • Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression
    • Akasaka T, van Lohuizen M, van der Lugt N, Mizutani-Koseki Y, Kanno M, et al. (2001) Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression. Development 128: 1587-1597.
    • (2001) Development , vol.128 , pp. 1587-1597
    • Akasaka, T.1    van Lohuizen, M.2    van der Lugt, N.3    Mizutani-Koseki, Y.4    Kanno, M.5
  • 30
    • 33746640565 scopus 로고    scopus 로고
    • Stem cells primed for action: Polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells
    • Jorgensen HF, Giadrossi S, Casanova M, Endoh M, Koseki H, et al. (2006) Stem cells primed for action: polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells. Cell Cycle 5: 1411-1414.
    • (2006) Cell Cycle , vol.5 , pp. 1411-1414
    • Jorgensen, H.F.1    Giadrossi, S.2    Casanova, M.3    Endoh, M.4    Koseki, H.5
  • 31
    • 1842411320 scopus 로고    scopus 로고
    • Crystal structure of the nucleosome core particle at 2.8 A resolution
    • Luger K, Mader AW, Richmond RK, Sargent DF, Richmond TJ (1997) Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 389: 251-260.
    • (1997) Nature , vol.389 , pp. 251-260
    • Luger, K.1    Mader, A.W.2    Richmond, R.K.3    Sargent, D.F.4    Richmond, T.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.