In vivo evolution of tigecycline-non-susceptible Klebsiella pneumoniae strains in patients: relationship between virulence and resistance

International Journal of Antimicrobial Agents

Volumn 48, Issue 5, 2016, Pages 485-491

  Lin, Yi Tsung ^a,b   Huang, Yi Wei ^b   Huang, Hsin Hui ^b   Yang, Tsuey Ching ^b   Wang, Fu Der ^a,b   Fung, Chang Phone ^c  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c CATHAY GENERAL HOSPITAL   (Taiwan)

Author keywords

Antimicrobial resistance; Efflux pump; Klebsiella pneumoniae; Tigecycline; Virulence

Indexed keywords

TIGECYCLINE; ANTIINFECTIVE AGENT; MINOCYCLINE; VIRULENCE FACTOR;

ACRA GENE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; CONTROLLED STUDY; DNA FINGERPRINTING; DNA SEQUENCE; GENE MUTATION; GENE OVEREXPRESSION; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; MULTILOCUS SEQUENCE TYPING; MUTATIONAL ANALYSIS; NONHUMAN; OQXA GENE; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; RAMA GENE; RARA GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RPSJ GENE; SEQUENCE ANALYSIS; STRAIN IDENTIFICATION; TAIWAN; UPREGULATION; AGED; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CLASSIFICATION; DISEASE MODEL; DRUG EFFECTS; FEMALE; GENETICS; HUMAN; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTIONS; MALE; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MIDDLE AGED; PATHOGENICITY; SURVIVAL ANALYSIS; VIRULENCE;

AGED; ANIMALS; ANTI-BACTERIAL AGENTS; DISEASE MODELS, ANIMAL; DRUG RESISTANCE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; FEMALE; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; MICE, INBRED C57BL; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MINOCYCLINE; MULTILOCUS SEQUENCE TYPING; SURVIVAL ANALYSIS; TAIWAN; VIRULENCE; VIRULENCE FACTORS;

EID: 84994000771     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2016.07.008     Document Type: Article

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