Inhibition of polyamine biosynthesis is a broad-spectrum strategy against RNA viruses

Journal of Virology

Volumn 90, Issue 21, 2016, Pages 9683-9692

  Mounce, Bryan C ^a   Cesaro, Teresa ^a   Moratorio, Gonzalo ^a   Hooikaas, Peter Jan ^a   Yakovleva, Anna ^a   Werneke, Scott W ^a,b   Smith, Everett Clinton ^c   Poirier, Enzo Z ^a,d   Simon Loriere, Etienne ^a   Prot, Matthieu ^a   Tamietti, Carole ^a   Vitry, Sandrine ^a   Volle, Romain ^a,b   Khou, Cécile ^a   Frenkiel, Marie Pascale ^a   Sakuntabhai, Anavaj ^a   Delpeyroux, Francis ^a,b   Pardigon, Nathalie ^a   Flamand, Marie ^a   Barba Spaeth, Giovanna ^a   Lafon, Monique ^a   Denison, Mark R ^c   Albert, Matthew L ^a,b   Vignuzzi, Marco ^a   more..

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EFLORNITHINE; N1,N11 DIETHYLNORSPERMINE; ACYLTRANSFERASE; ANTIVIRUS AGENT; DIAMINE N-ACETYLTRANSFERASE; N(1),N(11)-DIETHYLNORSPERMINE; POLYAMINE; SPERMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; DRUG EFFICACY; EPIDEMIC; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MOUSE MODEL; NONHUMAN; POLYAMINE SYNTHESIS; PRIORITY JOURNAL; RNA VIRUS; VIRUS CELL INTERACTION; VIRUS LOAD; VIRUS REPLICATION; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CELL LINE; CHIKUNGUNYA; CHIKUNGUNYA VIRUS; DRUG EFFECT; EBOLA HEMORRHAGIC FEVER; EBOLAVIRUS; METABOLISM; VIROLOGY; ZIKA FEVER; ZIKA VIRUS;

ACETYLTRANSFERASES; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CHIKUNGUNYA FEVER; CHIKUNGUNYA VIRUS; DISEASE OUTBREAKS; EBOLAVIRUS; EFLORNITHINE; HEMORRHAGIC FEVER, EBOLA; HUMANS; MICE; MICE, INBRED C57BL; POLYAMINES; RNA VIRUSES; SPERMINE; VIRUS REPLICATION; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 84993982760     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01347-16     Document Type: Article

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