Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 40, 2013, Pages 16157-16162

  Scobey, Trevor ^a   Yount, Boyd L ^a   Sims, Amy C ^a   Donaldson, Eric F ^a   Agnihothram, Sudhakar S ^a   Menachery, Vineet D ^a   Graham, Rachel L ^a   Swanstrom, Jesica ^a   Bove, Peter F ^b   Kim, Jeeho D ^b   Grego, Sonia ^c   Randell, Scott H ^b   Baric, Ralph S ^a,b  

^a IL   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c RTI INTERNATIONAL   (United States)

Author keywords

Emerging pathogen; Synthetic genome; Zoonosis

Indexed keywords

COMPLEMENTARY DNA; CONTIG; DIPEPTIDYL PEPTIDASE IV; RED FLUORESCENT PROTEIN; VIRUS GLYCOPROTEIN; VIRUS PROTEIN; VIRUS RNA;

AMINO ACID SEQUENCE; ARTICLE; CLONE; CONTROLLED STUDY; CORONAVIRUS; EPITHELIUM CELL; GENE CLUSTER; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENETIC TRANSFECTION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LUNG ALVEOLUS CELL TYPE 2; LUNG ENDOTHELIUM; LUNG FIBROBLAST; MARKER GENE; MICROVASCULAR ENDOTHELIAL CELL; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MOLECULAR CLONING; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RESPIRATORY EPITHELIUM; REVERSE GENETICS; RNA SYNTHESIS; SEQUENCE ANALYSIS; SEVERE ACUTE RESPIRATORY SYNDROME; TISSUE CULTURE; TISSUE SPECIFICITY; VIRAL GENETICS; VIRAL TROPISM; VIRUS CELL INTERACTION; VIRUS CHARACTERIZATION; VIRUS GENOME; VIRUS MUTATION; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS TRANSCRIPTION; WILD TYPE;

EMERGING PATHOGEN; SYNTHETIC GENOME; ZOONOSIS;

BLOTTING, NORTHERN; BLOTTING, WESTERN; CELLS, CULTURED; COMMUNICABLE DISEASES, EMERGING; CORONAVIRUS; DIPEPTIDYL PEPTIDASE 4; DNA PRIMERS; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION, VIRAL; HUMANS; LUMINESCENT PROTEINS; MIDDLE EAST; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; REAL-TIME POLYMERASE CHAIN REACTION; SEVERE ACUTE RESPIRATORY SYNDROME; SPIKE GLYCOPROTEIN, CORONAVIRUS; VIRUS ATTACHMENT; VIRUS REPLICATION;

EID: 84885038468     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1311542110     Document Type: Article

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