Epistasis between antibiotic resistance mutations and genetic background shape the fitness effect of resistance across species of pseudomonas

Proceedings of the Royal Society B: Biological Sciences

Volumn 283, Issue 1830, 2016, Pages

  Vogwill, T ^a,c   Kojadinovic, M ^a,b   Maclean, R C ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b AIX MARSEILLE UNIVERSITY   (France)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Antibiotic resistance; Fitness costs; Genetic background; Pseudomonas

Indexed keywords

ANTIBIOTIC RESISTANCE; BACTERIUM; ENZYME; EPISTASIS; FITNESS; GENE EXPRESSION; GENETIC ANALYSIS; GENOME; MUTATION; PARALLEL EVOLUTION; PATHOGEN;

BACTERIA (MICROORGANISMS); PSEUDOMONAS;

DNA DIRECTED RNA POLYMERASE; RIFAMPICIN;

ANTIBIOTIC RESISTANCE; DRUG EFFECTS; EPISTASIS; GENE EXPRESSION REGULATION; GENETICS; MUTATION; PHYLOGENY; PSEUDOMONAS;

DNA-DIRECTED RNA POLYMERASES; DRUG RESISTANCE, BACTERIAL; EPISTASIS, GENETIC; GENE EXPRESSION REGULATION, BACTERIAL; MUTATION; PHYLOGENY; PSEUDOMONAS; RIFAMPIN;

EID: 84993980188     PISSN: 09628452     EISSN: 14712954     Source Type: Journal    
DOI: 10.1098/rspb.2016.0151     Document Type: Article

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