Humanizing the protease-activated receptor (PAR) expression profile in mouse platelets by knocking Par1 into the Par3 locus reveals Par1 expression is not tolerated in mouse platelets

PLoS ONE

Volumn 11, Issue 10, 2016, Pages

  French, Shauna L ^a   Paramitha, Antonia C ^a   Moon, Mitchell J ^a   Dickins, Ross A ^a   Hamilton, Justin R ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

PADGEM PROTEIN; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 3; THROMBIN; CELL ADHESION MOLECULE; PARD3 PROTEIN, MOUSE; PROTEINASE ACTIVATED RECEPTOR;

ANIMAL CELL; ARTICLE; CELL LYSATE; CELL SPECIFICITY; CELL STIMULATION; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EXON; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE LOCUS; GENE SILENCING; GENE TARGETING; GENETIC ASSOCIATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; LOSS OF FUNCTION MUTATION; MOLECULAR DYNAMICS; NONHUMAN; PAR1 GENE; PAR3 GENE; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; WESTERN BLOTTING; WHOLE CELL; ANIMAL; GENETICS; METABOLISM; MOUSE;

ANIMALS; BLOOD PLATELETS; CELL ADHESION MOLECULES; GENE EXPRESSION PROFILING; MICE; RECEPTORS, PROTEINASE-ACTIVATED;

EID: 84992758991     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0165565     Document Type: Article

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