The protease-activated receptor 1 possesses a functional and cleavable signal peptide which is necessary for receptor expression

FEBS Letters

Volumn 586, Issue 16, 2012, Pages 2351-2359

  Zampatis, Dimitris E ^a,b   Rutz, Claudia ^a   Furkert, Jens ^a   Schmidt, Antje ^a   Wüstenhagen, Doreen ^c   Kubick, Stefan ^c   Tsopanoglou, Nikos E ^d   Schülein, Ralf ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c FRAUNHOFER INSTITUTE FOR BIOMEDICAL ENGINEERING   (Germany)

^d UNIVERSITY OF PATRAS   (Greece)

Author keywords

G protein coupled receptor; mRNA stability; PAR1; Signal peptide

Indexed keywords

G PROTEIN COUPLED RECEPTOR; MESSENGER RNA; PARSTATIN PEPTIDE; PEPTIDES AND PROTEINS; PROTEINASE ACTIVATED RECEPTOR 1; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; RNA STABILITY;

DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; NUCLEIC ACID CONFORMATION; PEPTIDE FRAGMENTS; PLASMIDS; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, PAR-1; RECEPTORS, G-PROTEIN-COUPLED; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; THROMBIN;

EID: 84864284157     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.05.042     Document Type: Article

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